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APLIKASI PENGENALAN AKSARA JAWA HANACARAKA BERBASIS AUGMENTED REALITY Susilo, Hendri; Sudargo, Sudargo; Menarianti, Ika
JIPETIK:Jurnal Ilmiah Penelitian Teknologi Informasi & Komputer Vol 2, No 2 (2021): JIPETIK : Jurnal Ilmiah Pendidikan Teknologi Informasi & Komputer
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/jipetik.v2i2.9719

Abstract

Penelitian ini dilatar belakangi karena menurunnya tingkat pemahaman dan kecintaan masyarakat khususnya anak-anak sekolah tehadap salah satu peninggalan budaya yaitu Aksara Jawa, juga media pembelajaran yang masih konvensional yang membuat minat belajar siswa untuk mempelajari Aksara Jawa menurun. Tujuan dari penelitian ini adalah meningkatkan minat belajar siswa Sekolah Dasar terhadap salah satu peninggalan budaya yaitu Aksara Jawa. Media pembelajaran yang dikembangkan penilis berupa aplikasi android yang menggunakan teknologi augmented reality. Augemnted reality merupakan teknologi yang menggabungkan benda maya 2D dan 3D kedalam lingkungan nyata 3 dimensi. Dengan menggunakan teknologi augmented reality diharapkan dapat meningkatkan minat belajar siswa untuk mempelajari Aksara Jawa. Metode pendekatan yang digunakan oleh peneliti adalah Penelitian dan Pengembangan (Research and Development) sedangkan model pengembangan menggunakan Waterfall Model . Target dalam penelitian ini adalah para siswa kelas 3 Sekolah Dasar di SD N 1 Lambur kecamatan Mrebet kabupaten Purbalingga. Pengolahan data diambil dari validasi ahli media, ahli materi, dan angket respon pengguna dengan menggunakan skala likert pada penliaiannya. Hasil validasi ahli media sebesar 81% persentase berikut masuk dalam kriteria “Sangat Layak” untuk digunakan, sedangkan dari validasi ahli materi sebesar 90% persentase berikut masuk dalam kriteria “Sangat Layak” untuk digunakan. Kemudian pengujian terhadap pengguna dilakukan kepada 15 responden, sehingga didapat hasil persentase sebesar 83.06% persentase berikut masuk dalam kriteria “Sangat Layak” untuk digunakan.
A NETWORK META-ANALYSIS: EFFICACY AND SAFETY OF ROTATIONAL ATHERECTOMY, ORBITAL ATHERECTOMY, AND INTRAVASCULAR LITHOTRIPSY COMPARISONS FOR NODULAR CORONARY LESIONS IN PERCUTANEOUS CORONARY INTERVENTION Handayani, Riana; Oktaviono, Yudi Her; Suryawan, I Gde Rurus; Susilo, Hendri; Aziz, Karimah Khitami; Erwan, Nabila Erina
Folia Medica Indonesiana Vol. 61, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Percutaneous Coronary Intervention (PCI) has continued to evolve since its introduction in 1977. Currently, 12% of all PCI procedures for coronary artery stenosis involve Calcified Nodules (CN). CN is defined as nodular calcification that protrudes into the lumen of the coronary artery. In this era, improving the feasibility and success of PCI is essential through the use of advanced techniques, innovative approaches, and specialized devices in coronary interventions. These techniques include Rotational Atherectomy (RA), Orbital Atherectomy (OA), and Intravascular Lithotripsy (IVL). Comparisons of RA, OA, and IVL are still being extensively studied in terms of their effectiveness and safety in treating complex lesions such as CN. Given the high costs of these devices, this Network Meta-Analysis (NMA) was conducted to evaluate and compare the efficacy and safety of RA, OA, and IVL based on recent studies. The primary analysis in this study was performed using MetaInsight V6.1.1, presenting odds ratios (OR) based on a Bayesian Network Meta-Analysis and ranking the interventions according to the Surface Under the Cumulative Ranking Curve (SUCRA). The primary outcomes assessed were efficacy and safety. Efficacy was defined as the procedural success rate, and safety as the overall safety rate of each procedure. Secondary outcomes included periprocedural complications (dissection, perforation, slow flow/no-reflow, cardiac tamponade, and device failure), as well as the incidence of major adverse cardiovascular events (MACE) within 30 days. The analysis revealed a statistically significant difference in efficacy between IVL and RA, favoring IVL (OR 2.66, 95% CrI: 1.27, 6.16). However, no statistically significant differences were observed in other primary or secondary outcomes among RA, OA, and IVL. Based on SUCRA rankings, OA was the most effective in preventing MACE, while RA showed the lowest risk of periprocedural complications. Nevertheless, this network meta-analysis has several limitations due to the uncertainty of the available data. Further research, including randomized controlled trials (RCTs) or larger cohort studies with direct comparisons of all three techniques (closed-loop designs), is warranted to validate these findings.
Beyond solely estrogen: Sex-based differences in platelet biology and antithrombotic response Salma, Zaskia Nafisa; Susilo, Hendri; Wungu, Citrawati Dyah Kencono; Tandecxi, Gabriel; Nugrahani, Annisa Salsabilla Dwi
Heart Science Journal Vol. 7 No. 2 (2026): The Evolving Landscape of Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.02.6

Abstract

Despite increased awareness of sex differences in cardiovascular disease (CVD), disparities in sex-specific platelet biology and antithrombotic studies are still underexplored. Moreover, women are frequently underrepresented in clinical trials, with numerous research initiatives primarily focusing on estrogen while neglecting non-hormonal influences that contribute variations in thrombotic risk and treatment outcomes. We conducted a literature review to examine sex-related differences in platelet biology, such as elevated platelet counts and reactivity in females, along with distinct expression of receptors and signaling molecules. These variations influence responses to antiplatelet medications—including aspirin, P2Y12 inhibitors, and glycoprotein IIb/IIIa inhibitors, and dual antiplatelet therapy—leading to altered effectiveness and a heightened bleeding risk in women. This review emphasizes the importance of non-hormonal factors, such as transcriptomic and proteomic variations, and highlights the growing potential of omics and systems biology in identifying therapeutic targets specific to sex. Incorporating sex as a biological factor in preclinical and clinical research is crucial for enhancing risk assessment and treatment results.