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Pengaruh Psikokuratif terhadap Kadar VEGF-c, Kortisol dan Skor HADS Pasien Kanker Serviks Stadium Lanjut Soetrisno, Soetrisno; Sulistyowati, Sri; Tjiang, Rubin Enhui; Wujoso, Hari; Nurinasari, Hafi; Cahyanto, Erindra Budi
JURNAL KESEHATAN REPRODUKSI Vol 7, No 1 (2020)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.50642

Abstract

Background: Cancer diagnosis and therapy that causes chronic stress, its progression to depression  increase cortisol and VEGF-c levels in advanced cervical cancer patientsObjective: To  know the VEGF-c, cortisol and HADS level  in advanced stage cervical cancer patients who get Psychocurative intervention Method : An experimental study of pretest – posttest controle group design in outpatient oncology clinic and ward of Doctor Moewardi General Hospital. Thirty subjects with advanced cervical cancer were randomly divided into 15 patients in the intervention group, and 15 in control. Psycho-curative intervention 4 times a month, 1 time a week, 60 minutes duration. Before and after intervention, each subject of the two groups was examined levels of VEGF-c, cortisol and HADS scores. Data obtained were analyzed by independent t test, Mann Whitney, Pair t and Wilcoxon with the 19th version of SPSS for Windows.Result and Discussion: Average VEGF-c levels before intervention 9006.53 ± 2181.49, after intervention 5631.20 ± 2071.55, p <0.001. The mean cortisol level before intervention was 12.29 ± 4.36, after intervention 6.71 ± 3.88, p <0.001. The mean HADS Anxiety score before intervention was 14.13 ± 3.02, after intervention 8.47 ± 3.07, p <0.001. Mean Depression HADS scores before intervention 13.80 ± 3.21, after intervention 7.20 ± 2.70, p <0.001.Conclusion : VEGF-c levels, cortisol, HADS anxiety scores and depression in patients with advanced cervical cancer decline after psychocurative intervention. Keywords : Psychocurative; VEGF-c; Cortisol; HADS; Cervical cancer
Enhancing Nutrients Knowledge during Pregnancy through Webinars to Prevent Stunting Bachnas, Muhammad Adrianes; Sulistyowati, Sri; Yuliantara, Eric Edwin; Anggraini, Nutria Widya Purna; Prabowo, Wisnu; Respati, Supriyadi Hari; Nurinasari, Hafi; Ridwan, Robert; Astetri, Lini; Yuliani, Saffana Oka; Carissa, Dinda; Alamsyah, Meuthia
Journal of Maternal and Child Health Vol. 7 No. 5 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (36.774 KB) | DOI: 10.26911/thejmch.2022.07.05.05

Abstract

Background: Indonesia still has a high stunting rate, 1.2 million out of 5 million births each year result in stunted baby growth. linear growth in utero, the process can be caused by maternal malnutrition, which can result in intrauterine growth inhibition and low birth weight, and result in stunting. This study aims to analyze the effectiveness of the webinar in improving nutrition knowledge during pregnancy to prevent stunting growth. Subjects and Method: This is a cross sectional study conducted in July, 15th 2022 using the Zoom Meeting webinar platform. Target population are all young POGI and POGI Members who took part in webinars and online conversations using the Zoom Meeting program. This study used random sampling, and sample size are 161. The independent variables of this study was learning via webinars while the dependent variable was nutrient knowledge. Data were analyzed by paired t-test statistical test. Results: There was a significant difference score of knowledge in pregnant women after (Mean= 8.60) compared to before webinars (Mean= 6.52). Conclusion: The result of this study indicates that learning method via webinars increased maternal understanding about optimal nutrient during pregnancy. Keywords: stunting, nutrients, webinar, pregnant women Correspondence: Nutria Widya Purna Anggraini. Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia. Jl. Kolonel Sutarto No. 132 Jebres, Surakarta. Email: nutria_dr@staff.uns.ac.id. Mobile: 08122651819.
Effect of Toxoplasma Infection Dosage on IgG, IgM, Fetus Weight and Body Length, and Necrosis of Placenta and Fetal Heart Nurinasari, Hafi; Sajidan; Purwanto, Bambang; Indarto, Dono; Subekti, Didik T
HAYATI Journal of Biosciences Vol. 31 No. 3 (2024): May 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.3.596-602

Abstract

One of the most prevalent zoonotic illnesses in the world, toxoplasmosis, affects both humans and animals and is caused by the parasite Toxoplasma gondii. The infection will trigger the immune system to increase antibody production. This study aims to determine the dose of toxoplasma that causes necrosis in rats placental and fetal hearts. This study was laboratory experimental research with a Randomized Control Trial (RCT). The study design used a post-test only with a control group design. The Ig G variable obtained from the control group (CG) and treatment group 3 (TG3) is the most significant because the mean value difference was the largest (176.56). The Ig M variable obtained from the control group with treatment group 3 (TG3) is the most significant because the mean value difference is the largest (33.47). The fetus weight variable obtained from the control group with treatment group 3 (TG3) is the most significant because the mean value difference is the largest (2.6). The body length variable obtained from the control group between treatment group 3 (TG3) is the most significant because the mean value difference is the largest (1.26). There was a significant difference in placental tissue necrosis (p = 0.034) and heart (p = 0.025) between the control group (CG) and treatment group 3 (TG3). Therefore, there was a significant difference in Ig G, Ig M, fetus weight, body length, placental tissue necrosis, and fetal heart at the 10³ dose compared to the 102, 101, and normal doses.
EDUKASI GIZI IBU: UPAYA PREVENTIF MENEKAN ANGKA STUNTING DI KABUPATEN SUKOHARJO JAWA TENGAH Nurinasari, Hafi; Anisya Nur Widya; Soetrisno; Selfia Bintariningtyas
Empowerment Journal Vol. 5 No. 1 (2025): Maret
Publisher : Universitas 'Aisyiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30787/empowerment.v5i1.1904

Abstract

Stunting merupakan masalah kesehatan yang menjadi isu prioritas di Indonesia, khususnya di Kabupaten Sukoharjo, dengan prevalensi sebesar 19,8%, melebihi target nasional 14%. Edukasi gizi bagi ibu hamil dan ibu dengan balita menjadi strategi utama dalam pencegahan stunting. Penelitian ini bertujuan untuk mengevaluasi efektivitas program edukasi gizi dalam meningkatkan pemahaman ibu terkait gizi seimbang dan pencegahan stunting dalam 1000 Hari Pertama Kehidupan (HPK). Penelitian ini menggunakan metode pre-eksperimental dengan desain one group pre-test dan post-test yang diolah menggunakan Orange Data Mining dan SPSS 22. Data dikumpulkan dari 37 peserta seminar penyuluhan gizi di Kecamatan Kartasura. Hasil penelitian menunjukkan peningkatan signifikan dalam pemahaman peserta, dengan rata-rata nilai pre-test 58,37 meningkat menjadi 74,05 pada post-test (p<0,05). Hasil ini membuktikan bahwa edukasi gizi yang terstruktur dan interaktif, efektif dalam meningkatkan literasi gizi ibu. Oleh karena itu, diperlukan program edukasi gizi yang berkelanjutan untuk menekan angka stunting dan meningkatkan kualitas kesehatan ibu dan balita
Syphilis in Pregnancy: Education to Increase Knowledge in Reproductive Couples Sulistyowati, Sri; Bachnas, Muhammad Adrianes; Yuliantara, Eric Edwin; Anggraini, Nutria Widya Purna; Respati, Supriyadi Hari; Nurinasari, Hafi; Ridwan, Robert; Astetri, Lini; Nuur, Aliffudin; Pradana, Muhammad Denny Gagah; Khoeronisa, Siti; Rahmawati, Oktantia Dyah
Journal of Maternal and Child Health Vol. 10 No. 4 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2025.10.04.01

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Background: Syphilis is believed to be one of the oldest diseases, first discovered in the late 15th century. Indonesian Ministry of Health reported a total of 76,923 new cases in 2020. WHO has set an ambitious target to reduce the incidence by 90% before 2030, in spite of slow global  response.  This number is lower than the number obtained in 2019, which was 4,169 people. Syphilis can be transmitted through sexual contact, blood transfusion, and vertical mother-to-child transmission (MTCT). It is estimated that the risk of transplacental infection ranges from 20-80%, depending on various factors, such as the stage of infection in the mother. This study aimed to assess the effect of counseling in increasing patient knowledge of syphilis cases in pregnancy. Subjects and Method: This was a quasi experiment conducted at obstetrics and gynecology department in Dr. Moewardi Hospital, Surakarta, Central Java, Indonesia, in June 2025. A sample of 84 pregnant women was selected for this study. The independent variable was counselling. The dependent variable was knowledge about Syphilis in pregnancy. Knowledge was tested before and after counselling. The data were examined using independent t test.             Results: The knowledge score of pregnant women about syphilis after the intervention (Mean= 77.14; SD= 13.85) was higher than before (Mean= 56.43; SD= 15.88), and it was statistically significant (p <0.001). Conclusion: The results of this study indicate that this recovery is effective in improving understanding of syphilis cases in pregnancy in obgyn polyclinic patients at Dr. Moewardi Hospital.
EFFECT OF AUTOGENIC TRAINING ON BULLYING-INDUCED ANXIETY IN CHILDREN Milinia, Straerla Atby; Argaheni, S.ST., M.Keb., Niken Bayu; Perestroika, Grhasta Dian; Novika, Revi Gama Hatta; Nurinasari, Hafi
Indonesian Midwifery and Health Sciences Journal Vol. 9 No. 2 (2025): Indonesian Midwifery and Health Sciences Journal, April 2025
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v9i2.2025.234-242

Abstract

Background: Bullying remains a common issue in character education at Islamic boarding schools, often manifesting in verbal and physical forms. Such experiences can cause significant anxiety in victims. One therapeutic option to address this is autogenic training, a relaxation technique aimed at reducing anxiety levels. Purpose: To determine the effect of autogenic training on reducing anxiety caused by bullying among students at Al-Ukhuwah Islamic Boarding School Sukoharjo, Central Java, Indonesia. Methods: This study employed a pre-experimental one-group pretest-posttest design involving 109 female students in grade VII, selected through total sampling. Participants completed the Olweus Bully Victim Questionnaire (OBVQ) and the Depression Anxiety Stress Scale (DASS-42) before the intervention. The autogenic training was conducted in 15-minute sessions, three times over three weeks. After the intervention, participants retook the DASS-42. Data were analyzed using the Wilcoxon test. Results: The Wilcoxon test showed a significant reduction in anxiety levels after autogenic training (p = 0.001). Before the intervention, most participants experienced severe to very severe anxiety; after the intervention, anxiety levels shifted to moderate and severe. Conclusion: Autogenic training effectively reduces anxiety among students who experience bullying. It is recommended as a supportive method to address students' mental health concerns in educational settings.
Impact of COVID-19 Pandemic on Postpartum Contraceptives Method Choice (IUD vs Tubectomy) and Characteristic Aspects: A Retrospective Descriptive Study Asih Anggraeni; Siagian, Grace; Nurinasari, Hafi; Wisdayanti, Syah Rini; Sulistyowati, Sri; Soetrisno
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 1 January 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i1.1966

Abstract

Objective: This study aims to assess the impact of the COVID-19 pandemic on postpartum contraceptive methods. Methods: This retrospective descriptive study was conducted at a single secondary center, utilizing secondary data retrieved from medical records at the Inpatient Installation of Sebelas Maret University Hospital, Surakarta, covering the period from January 2020 to January 2022. Results: Among users of intra-uterine devices (IUDs), 85% were below 35 years old, 65% were primiparous, 67% had a history of previous injectable contraceptive use, 79% received routine antenatal care, and 51% had education below a college level. These individuals were educated about the importance of contraceptive programs during the COVID-19 pandemic. Sixty-six percent of IUD insertions were conducted via vaginal delivery, and 27% had health facilities within less than 1 km. In contrast, tubectomy contraceptive users comprised 106 patients, with the majority (54%) being aged 35 years or older, all being multiparous, and 25% tested positive for COVID-19. Among tubectomy users, 43% had a history of previous injectable contraceptive use, 85% received routine antenatal care, and 54% had education below a college level. Similar to the IUD group, they were educated about the significance of contraceptive programs during the COVID-19 pandemic. Eighty-four percent of tubectomies were performed via cesarean section, and 27% of patients lived within less than 1 km from health facilities. Conclusion: The usage rates of intra-uterine devices and tubectomy for contraceptives remained stable during the COVID-19 pandemic. However, there was a decrease in postpartum in-person visits and mobility, coupled with an increase in hospitalizations.Keywords: contraceptive; family planning; intrauterine device; tubectomy