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Status 25(OH)D pada Penderita Sindrom Metabolik, Komponen Sindrom Metabolik, dan Orang Dewasa Sehat: 25(OH)D Status in Metabolic Syndrome, Metabolic Syndrome Components, and Healthy Adult Efriwati, Efriwati; Ernawati, Fitrah; Nurjanah, Nunung; Julianti, Elisa Diana; Aji, Galih Kusuma; Sundari, Dian; Retiaty, Fifi; Arifin, Aya Yuriestia
Amerta Nutrition Vol. 8 No. 4 (2024): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v8i4.2024.619-624

Abstract

Background: Vitamin D supplementation to prevent Metabolic Syndrome (MetS) has been widely implemented in developed countries and is now being introduced in developing countries. However, recent studies have shown no association between vitamin D and MetS in adults. Objectives: This study aims to obtain a profile of vitamin D values ​​in adults and explore vitamin D status in MetS patients, MetS components, and healthy adults. Methods: This research design was a cross-sectional study, utilizing both secondary and primary data from the research on the Risk Factors for Non-Communicable Diseases (RF-NCD) longitudinal study in 2021. Serum 25(OH)D levels in 956 adult respondents were determined by Enzyme-linked Immune Assay (ELISA) analysis using Stored Biological Material (SBM) serum from the 2021 RF-NCD longitudinal study. The ANOVA test was used to determine differences in vitamin D levels in various physiological conditions of respondents (MetS, MetS components, and healthy people). Results: A total of 68.5% of respondents had inadequate (deficiency and insufficiency) serum vitamin D levels, with an average of 26.5 ng/mL. The average vitamin D levels between MetS patients, MetS components, and healthy people were not significantly different (p-value>0.05). However, the number or percentage of respondents with 25(OH)D deficiency in the MetS group (12.1%) was higher than other physiological conditions. Conclusions: Most of the respondents in this study have inadequate vitamin D levels. The average vitamin D levels did not differ between physiological conditions. Further studies are needed on other micronutrient factors that affect the incidence of MetS and its components.
Evaluation of Bioactive Compounds, Antioxidant, and Anti-Diabetic Activities in Hexane and Supercritical Carbon Dioxide Extracts of Sweet Potato (Ipomoea batatas L.) Leaves Nasori, Achmad Sofian; Wiguna, Bangkit; Rahayu, Maya Damayanti; Permatasari, Devi; Kazfia, Hananda; Muhamaludin; Rosyidin, Ahmad Khulafaur; Dewi, Rizna Triana; Fu, Minghai; Atmaji, Priyo; Aji, Galih Kusuma
Science and Technology Indonesia Vol. 10 No. 1 (2025): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.1.250-261

Abstract

Sweet potato leaves are a rich source of bioactive compounds with potential health benefits. Advanced methods are being explored to harness these beneficial compounds efficiently. Applying the supercritical carbon dioxide (SCO2) technique, as an environmentally friendly extraction technique, offers many advantages over traditional solvent extraction. This study, therefore, aimed to investigate the effect of SCO2 extraction on the bioactive properties of sweet potato leaves, focusing on antioxidant and anti-diabetic activities. Then, the SCO2 extracts were compared with the hexane extract. A completely random design was used, performing 3 pressures (2000, 3000, and 4000 Psi) and 3 temperatures (40, 50, and 60°C) for the SCO2 extraction. In addition, a maceration using hexane solvent was performed in a shaker for 24 hours. Total polyphenol and flavonoid concentrations were quantified, and gas chromatography-mass spectrometry (GCMS) analyses were used to identify the extracted bioactive compounds. Antioxidant and anti-diabetic activities were also assessed. This yield of SCO2 extraction ranged from 0.49% to 0.89%, which was significantly lower in yield, polyphenol, flavonoid concentration, and antioxidant activity compared to hexane extract (P<0.05). Despite the lower yield, this study observed a higher concentration of bioactive terpenoids such as phytol, caryophyllene oxide, and squalene. In terms of anti-diabetic activity, the extracts at SCO2-specific conditions (4000 Psi 40°C, 3000 Psi 60°C, 3000 Psi 40°C, and 60°C, 2000 Psi 60°C) exhibited potent alpha-glucosidase inhibition, with IC50 values comparable to acarbose, and hexane extract. Dipeptidyl peptidase 4 (DPP4) inhibition was the highest in the hexane extract (p < 0.05), followed by SCO2 extracts. Thus, these findings highlight new possibilities for developing anti-diabetic agents derived from sweet potato leaves using the green SCO2 extraction technique.
EFFECT OF GINGER OLEORESIN CONCENTRATION ON THE ENCAPSULATION PROCESS USING IONIC GELATION Permana, Asep Wawan; Mardiyyah, Annisah; Wiguna, Bangkit; Laksono, Hendrawan; Aji, Galih Kusuma; Mufti, Ayi; Atmaji, Priyo; Muhamaludin; Budiyanto; Kusumasmarawati, Ambar Dwi; Prasetyo, Wegik Dwi; Sulaswatty, Anny; Nasori, Achmad Sofian
Jurnal Teknologi Industri Pertanian Vol. 34 No. 3 (2024): Jurnal Teknologi Industri Pertanian
Publisher : Department of Agroindustrial Technology, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24961/j.tek.ind.pert.2024.34.3.279

Abstract

The primary active components in ginger oleoresin are gingerol and shogaol, with gingerol exhibiting significant pharmacological activities such as anti-inflammatory, antioxidant, and analgesic effects. However, gingerol is heat-sensitive and degrades at elevated temperatures, limiting its functional efficacy when consumed. To overcome this limitation, encapsulation of ginger oleoresin was performed to enhance its physical and functional properties and improve its bioavailability. This study utilized the ionotropic gelation method to encapsulate ginger oleoresin, resulting in the formation of beads. Alginate was employed as the encapsulation matrix. The dried beads were characterized using FTIR, SEM, disintegration tests, and encapsulation efficiency was assessed via UV-Vis spectrophotometry. Results demonstrated that alginate beads containing ginger oleoresin could be successfully synthesized using the ionotropic gelation technique, with alginate as the polymer and CaCl2 as the cross-linking agent. Ginger oleoresin concentrations of 0.9%, 0.7%, 0.5%, and 0.3% were tested. The highest encapsulation efficiency, 72.48%, was obtained with a ginger oleoresin concentration of 0.7%. Surface morphology analysis revealed that the alginate beads exhibited a rough, porous texture with visible folds. Furthermore, the dry beads disintegrated within 30 minutes. Keywords: alginate, beads, encapsulation, ginger oleoresin, ionic gelation method
ANALISIS PERBANDINGAN KONSUMSI ENERGI DAN KEBUTUHAN ENERGI PADA PENYANGRAIAN BIJI KAKAO DENGAN SKALA BERBEDA Asmara, Sang Norma Lintang; Prasetyaningtyas, Cikha Ananda; Sari, Anjar Ruspita; Aji, Galih Kusuma; Hermawati, Budi Ariyani
Jurnal Teknologi Pertanian Andalas Vol 28 No 1 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jtpa.28.1.8-15.2024

Abstract

Proses penyangraian biji kakao pada skala laboratorium umumnya menggunakan roaster sederhana dengan bahan bakar LPG dan proses pembalikan biji secara manual. Hal ini menyebabkan kualitas pada biji hasil penyangraian tidak seragam pada tiap batch produksi. Berbeda dengan skala ganda, mesin penyangraian biji kakao sudah menggunakan bahan bakar listrik dan teknologi yang lebih canggih, sehingga dapat lebih mudah menjaga kualitas produk. Penelitian ini bertujuan untuk menganalisis kebutuhan energi dari perbedaan kedua kondisi penyangraian tersebut untuk mengoptimalkan proses produksi cokelat dengan skala yang sesuai. Metode penelitian yang dilakukan adalah melakukan dan mengamati proses penyangraian selama 60 menit. Parameter yang diamati meliputi kadar air, massa biji, dan suhu proses pada kedua skala. Selain itu diamati pula massa LPG yang terpakai untuk skala laboratorium dan daya listrik yang terpakai pada skala pilot. Hasil perhitungan konsumsi energi pada skala laboratorium adalah 5.277,295 kJ/kg dengan total biaya sebesar Rp. 8.437,5/kg. Sedangkan proses penyangraian skala pilot menggunakan listrik memerlukan energi sebesar 1.260 kJ/kg. Biaya listrik yang dikeluarkan jika menggunakan biaya dasar listrik tegangan rendah sebesar Rp1.699,53 per kWh, sehingga biaya listrik yang dikeluarkan kurang lebih sebesar Rp2.141,41/kg. Hasil penelitian menunjukkan bahwa penggunaan mesin sangrai dalam skala pilot lebih murah bila dilakukan produksi massal.
Evaluasi Konsumsi Nasi Sagu terhadap Parameter Gizi dan Biokimia pada Responden dengan Berat Badan Berlebih dan Kegemukan: An Evaluation of Sago-Rice Consumption on Nutritional and Biochemical Parameters in Overweight and Obese Participants Aji, Galih Kusuma; Hariyanto, Bambang; Pangestu, Alit; Kusumasmarawati, Ambar Dwi; Cahyana, Purwa Tri
Amerta Nutrition Vol. 9 No. 4 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i4.2025.576-585

Abstract

Background: Overweight and obesity are conditions caused by overnutrition, where an individual has an excessive nutrient intake. These conditions can lead to blood glucose and lipid problems. Sago rice, rich in resistant starch and fiber, offers a potential solution to this issue. Objectives: This study aimed to investigate the impact of eating sago rice over 4 weeks on the biochemical (glucose, total cholesterol, and triglyceride) and nutritional (body weight, Body Mass Index (BMI), total fat, and visceral fat contents) parameters in overweight and obese participants. Methods: Each participant consumed approximately 200 g of sago rice during lunch for 4 weeks. The researchers measured the participants’ body weight and height, which were then used to calculate their BMI before and after consuming the sago rice. They also performed Bioelectrical Impedance Analyses (BIA) to calculate the participants’ body and visceral fat percentages before and after consumption. The participant’s total cholesterol and triglycerides were also examined before and after the sago-rice consumption using the spectrophotometry method. Results: After 4 weeks of sago-rice consumption, the results highlighted a significant decrease in body weight, BMI, and body fat percentage (p-value<0.05). This study demonstrated that consuming sago rice for 4 weeks could significantly decrease the participants’ total cholesterol levels by approximately 18 mg/dL, from 257.33 mg/dL to 239.48 mg/dL (p-value<0.05). Conversely, the participants’ triglyceride levels increased (p-value<0.05). However, blood glucose concentration was not significantly different (p-value>0.05). Conclusions: Therefore, sago rice consumption can help reduce body weight, BMI, body fat percentage, and total cholesterol levels in overweight and obese individuals.