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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Research Journal of Life Science Jurnal Ilmiah Jophus: Journal of Pharmacy UMUS Medfarm: Jurnal Farmasi dan Kesehatan Jurnal EduHealth Stigma : Jurnal Matematika dan Ilmu Pengetahuan Alam Unipa Jurnal Farmasi Sains dan Praktis Jurnal Bakti Untuk Negeri Jurnal Mahasiswa Ilmu Kesehatan Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Abdimas Indonesia Bencoolen Journal of Pharmacy International Journal Of Public Health International Journal Of Health And Social Behavior Prosiding Seminar Nasional Ilmu Kesehatan dan Keperawatan
Arinda Nur Cahyani
STIKes Ibnu Sina Ajibarang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Penyuluhan DAGUSIBU di Desa Leduk Kecamatan Kembaran Kabupaten Banyumas Iva Rinia Dewi; Arinda Nur Cahyani; Anisa Annastasya
jurnal ABDIMAS Indonesia Vol. 1 No. 1 (2023): Maret: Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jai.v1i1.22

Abstract

Perkembangan ilmu pengetahuan dan teknologi telah merubah pola hidup dan pola pikir masyarakat. Kemudahan informasi juga semakin memudahkan masyarakat dalam mendapatkan obat-obat tersebut. Penggunaan obat yang sudah memasyarakat ini tidak diimbangi dengan kesadaran penggunaannya. Banyak masyarakat memperlakukan obat dengan kurang tepat. Hal tersebut menyebabkan obat tidak bisa berfungsi sebagaimana yang diharapkan. DAGUSIBU adalah prinsip yang harus diterapkan semua orang ketika membeli, menggunakan, menyimpan, serta membuang obat. DAGUSIBU sendiri merupakan bentuk akronim DApatkan, GUnakan, SImpan, dan BUang. Tujuan dari pengabdian masyarakat ini adalah untuk membina kader kesehatan peduli obat di tingkat Desa Ledug Kecamatan Kembaran dan memberikan edukasi kepada masyarakat agar dapat memperoleh, menggunakan, menyimpan dan membuang obat dengan benar sehingga dapat mencegah penggunaan obat yang tidak rasional. Metode yang digunakan dalam dalam pengabdian masyarakat kali ini adalah dengan memberikan penyuluhan dilanjutkan dengan sesi tanya jawab dan juga dilakukan pembagian leaflet agar masyarakat bisa melihat dan membaca kembali garis besat dari materi yang disampaikan. Evaluasi dilakukan dengan cara peserta mengisi kuisioner pretest dan posttest. Berdasarkan hasi pretest dan posttest menunjukan adanya peningkatan pengetahuan ditunjukan dengan hasil posttest yang meningkat. Kegiatan sosialisasi berjalan dengan baik dan lancar dan peserta antusias dalam menyampaikan pertanyaan. Kesimpulan: Dengan adanya penyuluhan tentang DAGUSIBU maka dapat meningkatkan pengetahuan dan kemudian diaplikasikan di lingkungan maupun keluarga.
PENGUATAN PEMAHAMAN PRODUK PANGAN AMAN DAN HALAL BAGI WARGA DESA BESUKI KECAMATAN LUMBIR KABUPATEN Arinda Nur Cahyani; Febia Citraeni Rusdaita; Elsa Nurmala
jurnal ABDIMAS Indonesia Vol. 1 No. 2 (2023): Juni: Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jurai.v1i2.38

Abstract

Food safety and product halalness are important matters and must be fulfilled for both micro industry and macro scale industry producers. One area that has many MSMEs is Besuki Village, Lumbir Banyumas District. The purpose of this community service is to strengthen and increase understanding and knowledge in determining safe and halal food. The method of implementing this activity is the provision of material and discussions which are conducted offline at the Besuki Village Hall. This activity took place on March 18 2023. The evaluation was carried out by giving a pre-test and post-test. The average value between experiencing an increase and after giving the material
ANALISIS KUALITATIF DAN KUANTITATIF BAHAN KIMIA OBAT (BKO) ANTALGIN PADA JAMU PEGAL LINU TIDAK BPOM YANG BEREDAR DI WILAYAH AJIBARANG Pratiwi Ayu; Arinda Nur Cahyani
Jurnal Mahasiswa Ilmu Kesehatan Vol. 1 No. 1 (2023): Januari : Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v1i1.21

Abstract

Penambahan BKO dalam jamu sangat dilarang, karena dapat mengakibatkan efek samping yang berbahaya bagi tubuh, yang sering ditambahkan BKO adalah jamu pegal linu seperti antalgin. Tujuan dari penelitian ini adalah untuk menentukan ada tidaknya kandungan antalgin di dalam jamu pegal linu yang beredar di wilayah ajibarang dan mengetahui berapa kadar antalgin yang terdapat dalam jamu pegal linu. Metode yang digunakan dalam penelitian ini adalah Reaksi Warna dan Kromatografi Lapis Tipis. Hasil Penelitian dari metode Reaksi Warna dari 5 sampel jamu pegal linu dinyatakan negatif mengandung antalgin dengan menggunakan pereaksi FeCL3 dan HCL 0,02N sesuai dengan FI III. Dilihat dari metode reaksi warna yang didapatkan hasil seluruh sampel negatif, dan dilanjutkan menggunakan metode kromatografi lapis tipis dilihat dari nilai Rf maka dinyatakan negatif mengandung bahan kimia obat antalgin.
FORMULASI, EVALUASI DAN UJI STABILITAS FISIK SEDIAAN GEL ANTIOKSIDAN EKSTRAK TALI PUTRI (Cassytha filiformis L) Setiawan, Roby; Masrijal, Camelia Dwi Putri; Hermansyah, Oky; Rahmawati, Suci; Sari, Rose Intan Perma; Cahyani, Arinda Nur
BENCOOLEN JOURNAL OF PHARMACY Vol. 3 No. 1 (2023): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v3i1.27649

Abstract

Tali putri (Cassytha filiformis L) termasuk ke dalam famili lauraceae, yang memiliki aktivitas antioksidan alami. Tanaman ini banyak dijumpai di kawasan pesisir Pantai Panjang Kota Bengkulu. Tujuan penelitiaan ini adalah mendapatkan formula gel antioksidan ekstrak Tali Putri (Cassytha filiformis L) terbaik berdasarkan evaluasi dan uji stabilitasnya. Tumbuahan Tali Putri (Cassytha filiformis L) diekstrak dengan metode maserasi selama 3x24 jam menggunakan pelarut metanol. Penelitian ini menggunakan ekstrak tali putri (Cassytha filiformis L) sebanyak 3%, yang diformulasikan ke dalam 3 formula dengan variasi basis HPMC, yaitu 7% (F1), 10% (F2), dan 15% (F3). Uji evaluasi yang dilakukan yaitu uji homogenitas, uji organoleptis, uji pH, dan uji viskositas. Uji stabilitas fisik menggunakan metode cycling test dilakukan selama 3 hari. Hasil pengujian randemen ekstrak yang diperoleh adalah 2,812%. Uji pH menunjukan gel memiliki pH 6,4 (F1), 6,3 (F2), dan 6,2 (F3). Uji viskositas menunjukan gel memiliki viskositas 2530 cps (F1), 1610 cps (F2), 1920 cps (F3). Uji stabilitas metode cycling test terjadi sineresis di setiap formulasi dengan waktu terlama pada F1. Gel mengandung ekstrak tali putri (Cassytha filiformis L) yang terbaik berdasarkan hasil evaluasi dan uji stabilitas adalah formula 1 (F1).
FORMULASI SEDIAAN PACTH ANTIPIRETIK EKSTRAK ETANOL RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb.) cahyani, arinda Nur; Miranti, Indira Pipit; Dewi, Iva Rinia; Susanto, Adi; ., Ma'rifah
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 13 No 2 (2024): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v13i2.417

Abstract

Demam adalah suatu keadaan dimana terjadi peningkatan suhu tubuh diatas normal, dikatakan demam jika suhu tubuh berada >37,5 OC. Temulawak (Curcuma xanthorrhiza Roxb.) mempunyai kandungan senyawa flavanoid yang telah dikenal memiliki efek antipiretik yang bekerja sebagai inhibitor enzim cyclooxygenase (COX) yang berperan dalam pembentukan prostaglandin. Penelitian ini bertujuan untuk memformulasikan sediaan patch ekstrak rimpang dan menguji efektivitasnya sebagai antipiretik. Jenis penelitian ini adalah ekperimental dengan metode variasi konsentrasi ekstrak rimpang temulawak (F1=0,45 gram; F2= 0,75 gram) serta pengujian efek antipiretik yang dilakukan dalam penelitian ini adalah induksi pepton sebanyak 1 ml secara intraperitoneal pada tikus. Hasil penelitian menunjukan kedua formulasi F1 dan F2 untuk uji organoleptik memiliki warna, bau, dan bentuk yang sama (warna keorange an, bentuk transdermal, dan bau khas temulawak); untuk uji homogenitas, susut pengeringan, ketebalan patch dan uji efektivitas antipiretik patch memenuhi persyaratan. Namun pada uji ketahanan lipatan patch belum memenuhi persyaratan yaitu >200 kali lipatan. Berdasarkan hasil tersebut patch rimpang temulawak belum memenuhi syarat dibuatnya sediaan patch, dikarenakan patch belum memenuhi syarat uji ketahanan lipatan. Uji efektivitas antipiretik diperoleh pada konsentrasi F1 = 0,45 gram ekstrak rimpang temulawak memiliki efektivitas antipiretik sebesar 36,1±0,3 OC dengan presentase penurunan demam sebesar 0,28% pada menit ke-60.
Evaluation of Drug Planning and Procurement Using the ABC-VEN and Reorder Point (ROP) Methods at Belik Public Health Center, Pemalang Regency In 2023 Iva Rinia Dewi; Annas Arfianto; Feri Kanti Rahayu; Arinda Nur Cahyani
International Journal of Public Health Vol. 1 No. 4 (2024): December : International Journal of Public Health
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijph.v1i4.463

Abstract

Community Health Centers (Puskesmas) are facilities established to implement promotive, preventive, curative, and rehabilitative health services by the government, local authorities, and the community. The system of drug planning and procurement plays a pivotal role in determining drug availability and the budget allocation required. This study aims to evaluate the process of drug planning and procurement using a combination of the ABC-VEN and Reorder Point (ROP) methods at the Belik Community Health Center, Pemalang Regency. This research is a descriptive analysis employing a retrospective case study design with data collection from January to December 2023 and supported by interviews. The results show that the ABC-VEN combination analysis identified: AV group (1 item; 0.29%; cost IDR 4,662,000), AE (45 items; 12.86%; IDR 271,578,813), AN (7 items; 2.00%; IDR 65,272,502), BV (7 items; 2.00%; IDR 7,825,526), BE (53 items; 15.14%; IDR 70,352,382), BN (11 items; 3.14%; IDR 15,283,936), CV (19 items; 5.43%; IDR 3,687,488), CE (194 items; 55.43%; IDR 42,690,036), and CN (13 items; 3.71%; IDR 2,779,589). Drugs in groups AN, BN, and CN (Additional group) should be prioritized for reduction; AE, BE, and CE (Main group) are second priority; while AV, BV, and CV (Priority group) must always be available. The highest Reorder Point (ROP) was for Dexamethasone at 64,067 tablets, while the lowest was Betason skin ointment with 0 tubes.
Optimization of Mannitol-Sucrose Mixture in Lozenges Containing Temu Ireng, Curcuma, Sand Ginger, and Ginger Using the SLD Method Arinda Nur Cahyani; Eko Hidayahturrohman Khumaeni; Indira Pipit Miranti; Iva Rinia Dewi; Yosi Soraya
International Journal of Health and Social Behavior Vol. 1 No. 4 (2024): November : International Journal of Health and Social Behavior
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhsb.v1i4.462

Abstract

Reduced appetite, diarrhea, cough, and joint pain are common health issues. Traditional medicinal plants such as Temu Ireng, Curcuma, Sand Ginger, and Ginger have been used to treat these conditions. This study aims to optimize the formulation of lozenges containing these plants using a combination of mannitol and sucrose as excipients through the SLD (Simple Lattice Design) method. Five formulations with varying ratios of mannitol and sucrose (FI = 75:25, FII = 25:75, FIII = 100:0, FIV = 0:100, FV = 50:50) were prepared using wet granulation. Granule physical properties were evaluated, and the optimum formulation was identified using statistical analysis including normality tests and one-sample t-tests. The results indicated that FI (mannitol 75%, sucrose 25%) provided the most desirable characteristics, with excellent granule flow, compressibility, and uniformity in lozenge quality. This research contributes to the development of herbal lozenges with optimized excipient combinations, enhancing the efficacy and quality of traditional medicine products.
EFEK PEMBERIAN INFUSA KOMBINASI TEMU IRENG, TEMULAWAK, KENCUR DAN JAHE TERHADAP BERAT MENCIT GALUR SWISS-WEBSTER Indira Pipit Miranti; Arinda Nur Cahyani; Eko Hidayaturohman; Ninstar Fathina Rifa
STIGMA: Jurnal Matematika dan Ilmu Pengetahuan Alam Unipa Vol 18 No 01 (2025)
Publisher : Universitas PGRI Adi Buana Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/stigma.8.01.10354.%p

Abstract

Signs that children have difficulty eating and will then trigger malnutrition are very limited nutritional intake and a reduced appetite. Temu ireng, curcuma, sand ginger and ginger rhizomes contain essential oils, curcumin, xanthorizol, gingerol and flavonoids in each plant which can increase body weight and appetite. The purpose of this study was to determine the effect and optimal frequency of infusion combination on body weight and feed consumption of mice. The research was conducted in the Pharmacology Laboratory of STIKes Ibnu Sina Ajibarang. This type of research is true experimental with pre-post-test control design method. 28 male mice were divided into four groups. Group P0 (aquadest), group P1 (½ x dose), group P2 (1x dose) and group P3 (1 ½ x dose). All treatment groups were acclimatized for 7 days, then treated according to the predetermined dose, then observed body weight gain and feed consumption for 28 days. Data analysis was conducted using paired t-test, One Way ANOVA test, and Post-hoc LSD test. The results showed that there was a significant effect on body weight gain in group P2 (p=0.000) and feed consumption in all groups in the first, third and fourth weeks. (p<0,05).   Keywords; Effect, Body Weight, Infusa, Rhizome.
Formulasi Krim Antibakteri Ekstrak Etanol Daun Awar-Awar (Ficus Septica Burm.) Terhadap Bakteri Staphylococcus Aureus Iva Rinia Dewi; Arinda Nur Cahyani; Marcello Ferrel Firmansyah
Prosiding Seminar Nasional Ilmu Kesehatan dan Keperawatan Vol. 1 No. 1 (2024): Juni : Prosiding Seminar Nasional Ilmu Kesehatan dan Keperawatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/prosemnasikk.v1i1.8

Abstract

Skin infection is a disease caused by microorganisms, one of which is Staphylococcus aureus bacteria. Treatment of skin infections can be done by using topical antibacterials such as creams. Previous studies have shown that awar-awar leaves have antibacterial activity against S. aureus. The purpose of this study was to determine the awar-awar leaf extract (Ficus septica Burm.) can be formulated as an active substance in cream preparations and to determine the preparation of awar-awar leaf extract cream (Ficus septica Burm.) has antibacterial activity against S. aureus bacteria. This research was conducted at the Microbiology and Pharmaceutical Technology Laboratory of STIKes Ibnu Sina Ajibarang. This type of research is experimental using wells diffusion method with concentration variation (F1=15%; F2=20%; and F3=25%). The positive control used was Gentamicin Cream (Bernofarm) and the negative control used was cream base. Parameters evaluated included antibacterial inhibition zone diameter, cream organoleptic, homogeneity, pH, spreadability, cream type, adhesiveness and cream stability. The results showed that the cream formulation made had met the criteria of the physical examination for cream formulations. The resulting cream formulation was homogeneous, had a pH range of 5 - 6, a spreadability of 5.135 cm to 5.177 cm, an oil-in-water cream type, and cream adhesion ranging from 2.45 seconds - 3.28 seconds. The antibacterial activity of cream formulations against S. aureus in F1, F2, and F3 were 2.46 mm, 3.29 mm, 5.44 mm respectively. Formulations F1 and F2 are classified as weak antibacterial while formulation F3 is classified as moderate antibacterial.
Evaluasi Penggunaan Antibiotik Pada Pasien Penyakit Paru Obstruksi Kronik Eksaserbasi Akut Di Instalasi Rawat Inap RSUD Ajibarang Rofik Kholid; Arinda Nur Cahyani; Dina Aulia
Prosiding Seminar Nasional Ilmu Kesehatan dan Keperawatan Vol. 1 No. 1 (2024): Prosiding Seminar Nasional Ilmu Kesehatan dan Keperawatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/prosemnasikk.v1i1.12

Abstract

Chronic Obstructive Pulmonary Disease is a common, preventable, and treatable disease characterized by persistent respiratory symptoms and airflow limitation due to abnormalities in the airways or alveoli. COPD symptoms include chronic or progressive dyspnea, cough with sputum production and respiratory infections. This study aims to determine the evaluation of antibiotic use in patients with Chronic Obstructive Pulmonary Disease (COPD) at Ajibarang Regional Hospital by examining the parameters of appropriate indication, appropriate drug, appropriate patient, appropriate dose and appropriate route of administration for 64 patients who met the inclusion criteria. This type of research uses a descriptive method with a total sampling technique using medical record data of COPD patients in the inpatient installation at Ajibarang Regional Hospital. The results obtained from this study were that men were more likely to be infected with COPD, with the age group 68 years and over being 37 patients (57.81%) and 60 years being 17 patients (26.56%). The profile of antibiotic use in COPD patients at Ajibarang Regional Hospital in 2022 is that there are seven types of antibiotics including ceftriaxone, azithromycin, cefixime, cefadroxil, levofloxacin, and cafazolin. evaluating the rationality of antibiotic use in patients with acute exacerbation of COPD, it can be concluded that the results of the evaluation of antibiotic use in patients with acute exacerbation of COPD are 100% correct indication, 100% correct drug, 89.06% correct dose, 100% correct patient and 100% correct route of administration . The conclusion of the study was that the most widely used antibiotic was ceftriaxone injection in 15 patients (23.43%). The rational use of antibiotics in COPD patients shows a percentage of 89.06%.
Co-Authors ., Ma'rifah Adi Susanto Adi Susanto Anisa A Anisa Annastasya Anna Nurlativah Annas Arfianto Asmiyenti Djaliasrin Djalil Dewi, Iva Rinia Dina Aulia Dwi Hartanti Dwi Hartanti Dwi Hartanti Dwi Hartanti Eko Hidayahturrohman Khumaeni Eko Hidayaturohman Eko Hidayaturrohman Khumaeni Elsa Nurmala Fadhilah Zahra Nadia Febia Citraeni Febia Citraeni Rusdaita Feri Kanti Rahayu Iswatun Nurhikmah Iva Rinia Dewi Marcello Ferrel Firmansyah Masrijal, Camelia Dwi Putri Miranti, Indira Pipit Ninstar Fathina Rifa Novita Endang Fitriyani Oky Hermansyah Pratiwi Ayu Ratih Widiyanti Rini Dwi Yuliana ROBY SETIAWAN Rofik Kholid Sari, Rose Intan Perma Septiana Liaturrohmah Suci Rahmawati Yosi Soraya Zainal Habib Gunawan Zainur Rahman Hakim