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Clinical and Laboratory Characterization of Hemodialysis Patients in Relation to Survival Outcomes at a Tertiary Referral Hospital in Indonesia Sipayung, Elisabeth; Nariata, I Wayan; Yassir; Satyawati, Rumaisah; Wijaya, Surya Oto; Budi, Gesang Setia; Anitha; Rivaldiansyah; Maemun, Siti; Widiantari, Aninda Dinar
Current Internal Medicine Research and Practice Surabaya Journal Vol. 6 No. 2 (2025): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v6i2.70810

Abstract

Introduction: Despite advancements in hemodialysis care, disease progression and outcomes in adults with various comorbidities, particularly in Indonesia’s overburdened tertiary hospitals, remain poorly characterized, limiting tailored care strategies. This study analyzed clinical characteristics and laboratory parameters among hemodialysis patients at Sulianti Saroso Infectious Disease Hospital, Jakarta, Indonesia, with stratification by survival outcomes. Methods: We conducted a retrospective cohort study of adults (>18 years) undergoing hemodialysis at Sulianti Saroso Infectious Disease Hospital between March and July 2024. Using purposive sampling, we analyzed 27 cases with documented laboratory parameters (i.e., blood urea nitrogen (BUN), serum creatinine, and estimated glomerular filtration rate (eGFR)) and clinical outcomes. Associations between outcomes and laboratory/clinical variables were assessed using Fisher’s exact test and logistic regression (p<0.05). Results: Mortality was reported in 25.9% of patients, including one who passed away due to complications related to coronavirus disease 2019 (COVID-19) shortly after being discharged. The leading indication for hemodialysis was hyperuricemia (85.2%), followed by chronic kidney disease. Nearly half of the patients (48.1%) had comorbid diabetes mellitus. Diabetic nephropathy was a key contributor to elevated urea levels. Prevalent complications reported among the patients included sepsis (70.4%) and glomerular disease (40.7%). Conclusion: This study found an association between diabetes mellitus and mortality in chronic kidney disease patients who underwent hemodialysis. Severe uremia, marked by elevated BUN levels, and symptomatic complications such as shortness of breath were observed, indicative of advanced disease progression. Earlier detection and optimized management are necessary to mitigate preventable morbidity in high-risk populations.   Highlights: 1. This study examined undercharacterized hemodialysis patients at an Indonesian tertiary hospital, focusing on high comorbidity burdens and outcomes. 2. Severe kidney disease and high mortality were observed, driven by comorbidities such as diabetes mellitus, hypertension, coronavirus disease 2019 (COVID-19), and infectious diseases (drug-resistant tuberculosis and hepatitis B/C). 3. The findings underscore the importance of optimized risk stratification and early intervention for end-stage renal failure in patients with both communicable and non-communicable disease comorbidities.
Utilization of Sludge from the Sulianti Saroso Hospital Wastewater Treatment Plant as Compost Material Anggraeni, Yeyen; Febrina, Laila; Mulyawati, Ira; Pratiwi, Tiara Zakiyah; Maemun, Siti
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7316

Abstract

Hospital activities generate by-products from the treatment of liquid waste, namely sludge that settles in sedimentation tanks. The sludge produced thus far has been transported by a third party in collaboration with the hospital. This study was conducted to utilize hospital wastewater treatment plant (WWTP) sludge with the aim of determining the moisture content, carbon (C) content, nitrogen (N) content, and C/N ratio in the raw WWTP sludge before and after composting compared to SNI 19-7030-2004 standards. Additionally, the study aimed to identify the average differences in each variation of WWTP sludge and rice husk composition. This research employed an experimental method. The composting process was conducted aerobically with the following variations: 95% WWTP sludge:5% rice husk (A1), 85% WWTP sludge:15% rice husk (A2), 75% WWTP sludge:25% rice husk (A3), and 65% WWTP sludge:35% rice husk (A4), with the addition of EM4 activator 55 ml + 90 ml sugar solution diluted to 300 ml. The preliminary test results for the WWTP sludge showed a moisture content of 68.76%, C content of 28.00%, N content of 14.32%, and C/N ratio of 1.95. From the results of the ANOVA statistical test and Post Hoc Duncan test, it was found that the average variation in WWTP sludge: rice husk composition had a significant difference, with the ideal composition being variation A1 (95% WWTP sludge:5% rice husk).