Article Per Year (5 Year)
p-Index From 2021 - 2026
1.817
P-Index
This Author published in this journals
All Journal Journal of Health Sciences Medical and Health Science Journal Medicra (Journal of Medical Laboratory Science/Technology) Indonesian Journal of Cancer CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Journal of Pharmaceutical and Sciences. Surabaya Biomedical Journal Surabaya Biomedical Journal Indonesian Journal of Global Health Research
Wibowo, Prajogo
Universitas Hang Tuah
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 12 Documents
Search

 1   2 
EFEK QUERCETIN DARI BUAH DELIMA (PUNICA GRANATUM L.) TERHADAP PENURUNAN GLUKOSA DARAH: 58-72 Barkha Agung Priyanto; Prajogo Wibowo
Surabaya Biomedical Journal Vol. 1 No. 1 (2021): September
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v1i1.9

Abstract

Delima (Punica granatum L.) lebih dikenal di beberapa negara sebagai buah Eden, karena rasanya yang enak dan khasiatnya yang bermanfaat bagi kesehatan. Buah delima dan ekstrak buah delima telah terbukti memiliki aktivitas pencegahan dan penghambatan terhadap berbagai penyakit kronis dan mengancam kesehatan atau kehidupan. Diabetes tipe 2 dapat dicegah dan di obati dengan senyawa quercetin.Quercetin merupakan flavonoid paling popular yang banyak terkandung dalam sayuran dan buah-buahan.Flavonoid signifikan menurunkan kadar gula darah, meningkatkan ekspresi GLUT4, dan memperkuat penyerapan glukosa pada permukaan sel otot tulang dengan menstimulasi Adenosin Monofosfat Protein Kinase (AMPK). Untuk mengetahui efek pemberian quercetin terhadap penurunan kadar glukosa dalam darah pada pasien diabetes melitus tipe 2. Penelitian ini menggunakan desain penelitian deskriptif dengan metode studi literatur minimal 15 artikel dari jurnal nasional yang terindeksSINTA dan jurnal internasional yang terindeks Scimago dengan batasan tahun 2015-2020. Kandungan flavonoid dari quercetin memiliki efek pada pasien diabetes melitus tipe 2 dengan menjadi ligan yang mampu memperbaiki reseptor (AMPK, GLUT 4, SIRT1, nuclear factor kappa (NF-kB)) sehingga dapat mengendalikan gen sel adiposa atau transkripsi lainnya yang memengaruhi resistensi insulin pada pasien diabetes tipe 2. Kesimpulan yang saya dapatkan dari hasil penelitian studi literature ini adalah quercetin dapat mempengaruhi dalam penurunan kadar glukosa dalam darah.
The Relationship between Risk Factors and Characteristics of People with Nasopharyngeal Carcinoma Veranika Ekklesia Andita; Muhammad Noer Shoffi; Ketut Tirka Nandaka; Prajogo Wibowo
Indonesian Journal of Global Health Research Vol. 8 No. 3 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i3.1278

Abstract

Nasopharyngeal carcinoma (KNF) is a malignant cancer that originates from the nasopharyngeal epithelium and is one of the leading causes of cancer death in Indonesia. This disease is related to various environmental and genetic risk factors such as salted fish consumption, smoking habits, exposure to wood burning smoke, alcohol consumption, and genetic factors. Exposure to wood burning smoke contains carcinogenic compounds that can cause chronic irritation and DNA mutations in nasopharyngeal epithelial cells. This study aims to determine the relationship between salted fish consumption patterns, smoking habits, exposure to wood burning smoke, alcohol consumption, and genetic factors with the incidence of nasopharyngeal carcinoma at RSPAL dr. Ramelan Surabaya for the period March 2020 to March 2025. Cross-sectional research was carried out at RSPAL dr. Ramelan Surabaya. A total of 49 consisting of 36 patients with nasopharyngeal carcinoma and 13 non-nasopharyngeal carcinoma patients were selected by total sampling. The dependent variable is nasopharyngeal carcinoma. Independent variables were salted fish consumption patterns, exposure to wood burning smoke, smoking habits, alcohol consumption and genetics. Data was collected using questionnaires that had been tested for validity and reliability, and medical records. The data was analyzed by Chi-square test. There was a significant association between exposure to wood burning smoke and the incidence of nasopharyngeal carcinoma (p = 0.036). Meanwhile, salted fish consumption patterns (p = 0.165), smoking habits (p = 0.586), alcohol consumption (p = 0.288), and genetic factors (p = 0.609) showed no meaningful relationship. This shows that exposure to wood burning smoke is the most influential environmental factor on the incidence of KNF at the research site. There was a significant association between exposure to wood burning smoke and the incidence of nasopharyngeal carcinoma, while salted fish consumption patterns, smoking habits, alcohol consumption, and genetic factors did not show a significant relationship.
Co-Authors Anita Carolina Barkha Agung Priyanto Chandra, Eka Narayana Dewi, Lestari Handajani, Fitri Haryati, Tallia Irawati, Ade Ketut Tirka Nandaka Leksodimulyo, Marcella Clarineta Muhammad Noer Shoffi Mutiadesi, Wahyu Prasasti Nanuru, Erika Widianingsih Payangka, Jonathan Pratama A., Ronald Prawesty Diah Utami Purbowo Sintoro, Henry Renata Prameswari Riami Risma Risma, Risma Ulfa, Nadiyah Veranika Ekklesia Andita Verna Biutifasari Vijaya, Ailya Tefanya Yudadi, Redemptus Zenjaya, Kellyn Trycia