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All Journal The Indonesian Biomedical Journal Jurnal Kesehatan Komunitas Amerta Nutrition Majalah Kedokteran Andalas Jurnal Ilmu dan Teknologi Kesehatan Andalas obstetrics and gynecology journal Best Journal (Biology Education, Sains and Technology)
Karmia, Hudila Rifa
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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The Role Of Vitamin D And Calcium In Pre-Eclampsia And The Association With Neonatal Outcomes Fadila, Tara; Yusrawati, Yusrawati; Karmia, Hudila Rifa
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.253-266.2023

Abstract

Introduction: Pre-eclampsia is one of the main causes of maternal and neonatal death in developingcountries. A low vitamin D level can increase the risk of neonatal abnormalities. Clinical studiesreported various complications of low vitamin D levels, such as pre-eclampsia, gestational diabetes,low birthweight, and caesarean section. This study aimed to investigate the role of vitamin D inpregnancy with pre-eclampsia and its association with neonatal outcomes.Methods: This is an observational analytical study uses a cross-sectional approach to investigatevitamin D levels and pre-eclampsia, conducted in General Hospital Dr. M. Djamil Padang from Mei2021 – April 2022. A total of 5 mL blood was withdrawn to analyzed vitamin D. This study has beenapproved by Health Research Ethics Committee Andalas University (Approved number:339/KEPK/2021).Results: There was a significant difference in the levels of 1,25 dihydroxy vitamin D3 between normalpregnancy and pre-eclampsia patients (99,18 vs 72,53 pg/ml; p = 0,033). In the pre-eclampsia patients’first APGAR score, there was a significant difference in the levels of 1,25 dihydroxy vitamin D3 betweennormal, moderate, and severe asphyxia groups (114,19 vs 66,75 vs 74,78 pg/ml; p = 0,025).Conclusion: Measuring early maternal 1,25 dihydroxy vitamin D3 can lower the pre-eclampsia risksand the impact the perinatal outcomes, particularly in determining first Apgar scores.
Characteristics of Advanced Epithelial Ovarian Cancer Patients in Dr. M. Jamil Padang Hospital Azwan, Reyhan Julio; Muhammad, Syammel; Karmia, Hudila Rifa
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.560-568.2024

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Background: Ovarian cancer is a major global health concern, often diagnosed at advanced stages, impacting five-year survival rates. This study examines the demographic and clinical characteristics of 64 patients with advanced epithelial ovarian cancer, shedding light on the disease complexity. Methods: Conducted at General Hospital Dr. M. Djamil Padang, this cross-sectional study analyzed patient data using SPSS. The research, approved by the Health Research Ethics Committee of Andalas University, included detailed demographic and clinical assessments. Results: Predominantly, patients were aged 40-64, exhibited normal BMI, and a significant portion had not given birth. Evaluation of clinical factors, including Peritoneal Cancer Index (PCI) and residual tumor size, provided insights into the cohort's characteristics. Optimal cytoreduction (<1 cm residual tumor) was prevalent, emphasizing the role of surgery in enhancing survival. Conclusion:The study underscores the multifaceted nature of advanced epithelial ovarian  cancer and advocates personalized treatment approaches tailored to individual patient profiles. The findings contribute valuable insights to the existing knowledge, emphasizing the importance of age, BMI, and surgical interventions in influencing outcomes.
Correlation of Maternal Serum 25 Hydroxy Vitamin D with Newborn Anthropometry Iqbal, Muhammad; Yusrawati, Yusrawati; Karmia, Hudila Rifa; Serudji, Joserizal
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.579-585.2024

Abstract

Vitamin D deficiency (VDD) is identified as a public health problem in many countries, and pregnant women have been identified as a high-risk group, among whom the prevalence of VDD ranges between 20 and 40%. Vitamin D deficiency causes essential health problems, not only in the mother but also in the baby, because the mother's vitamin D stores are the primary source of vitamin D for the fetus. During pregnancy, severe vitamin D deficiency in mothers has been associated with biochemical evidence of impaired bone homeostasis, congenital rickets, and bone fractures in newborns. This study aims to determine the correlation between umbilical cord blood 25(OH)D levels in term pregnancy and Neonatal anthropometry. This research is analytical research using a cross-sectional approach. The sample in this study amounted to 40 people. Data analysts use people tests. The results of this study obtained an average umbilical cord serum 25(OH)D level of 14.70 ± 4.93. There was no correlation between umbilical cord blood 25(OH)D levels in term pregnancy and neonate anthropometry (p>0.05). The average level of 25(OH)D is included in the insufficiency category. Therefore, it is necessary to increase vitamin D supplementation during pregnancy.
Co-Authors Abdiana Abdiana, Abdiana Alvarino Alvarino Amizuar, Yulia Fauziah Antonius, Puja Agung Aswiyanti Asri Azwan, Reyhan Julio Basyir, Vaulinne Desmawati Desmawati Dzaky, Aditya Luthfian Eti Yerizel Fadila, Tara Firdawati, Firdawati Fitri Anggraini, Fitri Ginting, Desi Scorpinasari Hardisman Hasmiwati Jamsari Jamsari Malinda Meinapuri Muhammad Iqbal Muhammad, Syammel Noza Hilbertina, Noza Rafika Oktova Ramya Sausan Rauza Sukma Rita Rima Semiarty Risanti, Suci Padma Sari, Asti Marian Syamel Muhammad Wijaya, Caesar Muhammad Yusrawati Yusrawati