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Characteristics of Advanced Epithelial Ovarian Cancer Patients in Dr. M. Jamil Padang Hospital Azwan, Reyhan Julio; Muhammad, Syammel; Karmia, Hudila Rifa
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.560-568.2024

Abstract

Background: Ovarian cancer is a major global health concern, often diagnosed at advanced stages, impacting five-year survival rates. This study examines the demographic and clinical characteristics of 64 patients with advanced epithelial ovarian cancer, shedding light on the disease complexity. Methods: Conducted at General Hospital Dr. M. Djamil Padang, this cross-sectional study analyzed patient data using SPSS. The research, approved by the Health Research Ethics Committee of Andalas University, included detailed demographic and clinical assessments. Results: Predominantly, patients were aged 40-64, exhibited normal BMI, and a significant portion had not given birth. Evaluation of clinical factors, including Peritoneal Cancer Index (PCI) and residual tumor size, provided insights into the cohort's characteristics. Optimal cytoreduction (<1 cm residual tumor) was prevalent, emphasizing the role of surgery in enhancing survival. Conclusion:The study underscores the multifaceted nature of advanced epithelial ovarian  cancer and advocates personalized treatment approaches tailored to individual patient profiles. The findings contribute valuable insights to the existing knowledge, emphasizing the importance of age, BMI, and surgical interventions in influencing outcomes.
Correlation of Maternal Serum 25 Hydroxy Vitamin D with Newborn Anthropometry Iqbal, Muhammad; Yusrawati, Yusrawati; Karmia, Hudila Rifa; Serudji, Joserizal
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.579-585.2024

Abstract

Vitamin D deficiency (VDD) is identified as a public health problem in many countries, and pregnant women have been identified as a high-risk group, among whom the prevalence of VDD ranges between 20 and 40%. Vitamin D deficiency causes essential health problems, not only in the mother but also in the baby, because the mother's vitamin D stores are the primary source of vitamin D for the fetus. During pregnancy, severe vitamin D deficiency in mothers has been associated with biochemical evidence of impaired bone homeostasis, congenital rickets, and bone fractures in newborns. This study aims to determine the correlation between umbilical cord blood 25(OH)D levels in term pregnancy and Neonatal anthropometry. This research is analytical research using a cross-sectional approach. The sample in this study amounted to 40 people. Data analysts use people tests. The results of this study obtained an average umbilical cord serum 25(OH)D level of 14.70 ± 4.93. There was no correlation between umbilical cord blood 25(OH)D levels in term pregnancy and neonate anthropometry (p>0.05). The average level of 25(OH)D is included in the insufficiency category. Therefore, it is necessary to increase vitamin D supplementation during pregnancy.
Analysis of Factors Related to the Use of Iud Contraceptives in the Working Area Kristiya, Ikke; Nurhajjah, Siti; Karmia, Hudila Rifa
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.2729

Abstract

The growth of the world's population is increasing day by day, the increase in the number of people also has an impact on the maternal mortality rate (AKI), The factor that causes the increase in population is the lack of people in the use of contraception, especially in the use of long-term contraception, one of which is IUD. The purpose of this study is to find out "Factors Related to the Use of IUD Contraceptives in the Working Area of the Andalas Padang Health Center This type of research is analytical with a Cross Sectional design, which will be carried out from June 2024 to January 2025. A sample of 68 PUS people using IUD contraceptives was taken using propotional random sampling. Data collection was conducted using questionnaires and analyzed using Chi Square and Logistic Regression tests. The results of the study found that the level of knowledge was high (69.1%), positive attitude (79.4%), support for husbands who did not support (60.3%), and support for health workers (75.0%). Based on multivariate results, it was found that the most dominant factor related to the use of IUD contraceptives was the husband's support with the highest OR value of 4,398. The conclusion of this study found that there was a relationship between the level of knowledge, attitude, husband support and health worker support. The most dominant factor is the husband's support. It is hoped that there will be cross-sectoral cooperation and education in the role of husbands to increase the use of IUD contraceptives in PUS.
The Relationship of Age with TNF-α Levels in Pregnancy and Abortion Monika, Cici; Revilla, Gusti; Karmia, Hudila Rifa; Nurhajjah, Siti; Welan, Rahmani
Andalas Obstetrics And Gynecology Journal Vol. 10 No. 1 (2026)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.10.1.97-107.2026

Abstract

Introduction: Tumor Necrosis Factor Alpha (TNF-α) plays a crucial role in the early control of abortion. This increase can be influenced by age. The purpose of this study was to analyze the relationship between age and TNF-α in both normal pregnancies and abortion. Method: The type of research is analytic with a cross sectional design, collecting samples using total sampling technique, resulting in 36 patients who were subsequently assessed for TNF-α levels at the Biomedical Laboratory of Andalas University. The source of research data is secondary data. Data analysis involved the Spearman correlation test, Independent T-test, and Mann-Whitney test. Result: The average gestational age was younger, the average maternal age was older, and the average TNF-α levels were higher in abortion compared to normal pregnancy. The BMI of all patients was normal. There is a significant difference between age in normal pregnancy and abortion (p = 0.001), there is no relationship between age and TNF-α levels in normal pregnancy (p = 0.429), there is no relationship between age and TNF-α levels in abortion (p = 0.862), and there is no difference in TNF-α levels between normal pregnancy and abortion (p = 0.248). Conclusion: there is a significant difference between age in normal pregnancy and abortion.