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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Media Farmasi JURNAL FARMASIMED (JFM) Amalee: Indonesian Journal of Community Research & Engagement Yumary: Jurnal Pengabdian kepada Masyarakat Journal Of Human And Education (JAHE) Jurnal Kefarmasian Indonesia
Awaluddin, Akbar
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Edukasi Siswa melalui Pengenalan Profesi Apoteker pada Program Kelas Inspirasi di SDN Parinring Makassar Awaluddin, Nurhikma; Awaluddin, Akbar
Amalee: Indonesian Journal of Community Research and Engagement Vol 4 No 1 (2023): Amalee: Indonesian Journal of Community Research and Engagement
Publisher : LP2M INSURI Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/amalee.v4i1.2502

Abstract

Pharmacists are the source of information about drugs, but many people still need to familiarize themselves with the pharmacist profession. This causes problems for children as well as adults who lack knowledge about medicines in children, which can lead to drug abuse. This activity aims to educate elementary school students about the introduction of the pharmacist profession, an introduction to drugs, and to foster curiosity about the pharmacist profession from an early age. This activity was carried out at SD Negeri Parinring, Kec: Manggala, Makassar, with 35 participants from grade 6 elementary school students. The Participatory Rural Appraisal (PRA) model is used in community service activities, promoting community empowerment to participate. The action begins with an introduction to material delivered by pharmacists. After that, sing the pharmacist's jingle, and give questions to test the extent of drug knowledge possessed by elementary school students, the results of this community service, especially at SD Negeri Parinring, Kec. Manggala, Makassar can increase understanding and drug awareness early to minimize unwanted side effects and become an agent of change who can explain the confusion of drug information circulating among students.
Efektivitas Ekstrak Daun Kelor (Moringa oleifera L.) Untuk Ulkus Peptikum Pada Tikus Putih (Rattus norvegicus) Yang Diinduksi Aspirin Indrisari, Maulita; Khairi, Nur; Muslimin, Lukman; Awaluddin, Akbar; Arisah, Arisah
Media Farmasi XXX Vol 19, No 1 (2023)
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar, Kementerian Kesehatan RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v19i1.3292

Abstract

Effectiveness of Moringa Leaf Extract (Moringa oleifera L.) for Peptic Ulcuses In Aspirine-Induced White Rats (Rattus norvegicus)Moringa (Moringa oleifera L). is a plant that is known for its multipurpose, nutrient-dense, and medicinal properties. Moringa leaves contain flavonoid compounds, namely β-sitosterol which can reduce ulcers in the stomach. This research used 15 male white rats divided into 5 groups, namely the normal group, CMC Na (Negative), ranitidine (Positive), and treatment with extract doses of 100 and 300 mg/kg BW. Test animals were induced by aspirin at a dose of 500 mg/kg for 7 days, then given treatment for 7 days, except for the normal group. On the 15th day, all groups were sacrificed, then the gastric organs were visually observed, and the ulcer index was measured. the observations it was found that the administration of the extract at a dose of 300 mg/kgBB decreased the number of ulcers compared to the positive control group (p>0.05). The extract dose of 300 mg/kg BW reduces the number of aspirin-induced ulcer diameters. The results of statistics with Kruskall-Wallis, there was a significant difference after treatment (p<0.05), but there was no significant difference between groups (p>0.05). Ethanol extract of Moringa leaves at a dose of 300 mg/kgBB can be gastroprotective in aspirin-induced male white rats.Keyword: Moringa leaves, gastroprotective, gastric ulcer, aspirinKelor (Moringa oleifera L).merupakan tanaman yang dikenal multi guna, padat akan nutrisi dan bermanfaat sebagai obat. Daun kelor mengandung senyawa flavonoid, yakni β-sitosterol yang dapat mengurangi tukak pada lambung. Penelitian ini menggunakan tikus putih jantan sebanyak 15 ekor yang dibagi dalam 5 kelompok yaitu kelompok normal, Na CMC (Negatif), ranitidine (Positif), dan perlakuan dengan dosis  ekstrak 100 dan 300 mg/kgBB. Hewan uji di induksi aspirin dosis 500 mg/kgBB selama 7 hari, kemudian diberi pengobatan selama 7 hari, kecuali kelompok normal. Pada hari ke-15 semua kelompok dikorbankan kemudian diamati organ lambung secara visual diukur indeks tukak. Dari hasil pengamatan diketahui bahwa pemberian ekstrak dosis 300 mg/kgBB terjadi penurunan jumlah tukak dibandingkan dengan kelompok kontrol positif  (p>0,05). Dosis ekstrak 300 mg/kgBB memberikan efek penurunan jumlah diameter tukak akibat induksi aspirin. Berdasarkan hasil perhitungan dengan Kruskall-Wallis menunjukkan adanya perbedaan yang signifikan setelah perlakuan (p<0,05), namun tidak menunjukkan perbedaan signifikan antar kelompok (p>0,05). Ekstrak etanol daun kelor dengan dosis 300 mg/kgBB memiliki kemampuan sebagai gastroprotektif pada tikus putih  jantan yang diinduksi aspirin.Keyword : Daun kelor, gastroprotektif, tukak lambung, aspirin
Pengaruh Fraksi Daun Asam Jawa (Tamarindus indica L.) terhadap Fungsi Hati dan Ginjal Tikus Diinduksi Parasetamol Rahimah, Sitti; Awaluddin, Akbar; Wahyuddin, Nurzadrina
Jurnal Kefarmasian Indonesia VOLUME 12, NOMOR 2, AGUSTUS 2022
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v0i0.5955

Abstract

Liver and kidneys play a role in the metabolism and excretion of substances that enter the body, they become targets for toxicity from xenobiotics and other chemicals including drugs. Exogenous antioxidants are needed to overcome and prevent oxidative stress. Fraction of tamarind leaf extract (Tamarindus indica L) has antioxidant activity, it has the potential to protect the body from free radicals. This study aimed to determine the effect of giving tamarind leaf fractions on AST, ALT and creatinine levels in rats (Rattus norvegicus) induced with paracetamol. Experimental animals were divided into 4 groups. Group I was given paracetamol induction (negative control), group II was given the ethyl acetate fraction and induced paracetamol, group III was given the n-hexane fraction and induced paracetamol, and group IV was without treatment (positive control). Statistical analysis using One Way Anova test and LSD (Post Hoc) showed that the ethyl acetate fraction was not significantly different (p-value >0.05) with the positive control group and the n-hexane fraction group, but significantly different from the negative control group (p -value
Edukasi TPS 3R Darul Aman dan Masyarakat dalam Optimasi Pembuatan Pupuk Kompos di Pondok Pesantren Darul Aman, Gombara, Makassar, Sulawesi Selatan Abdul Malik, Fhahri Mubarak; Khairuddin, Khairuddin; Aksa, Rahmad; Awaluddin, Akbar; Hapiwaty, Saldi; Ismail , Ismail; Azwar, Muhammad; Pranata, Andriy
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 3 (2024): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v4i3.2603

Abstract

Purpose: Helping TPS 3R partners to solve the problem of managing waste into compost is efficient and effective. Methodology: carried out at TPS 3R Darul Aman, method of implementing innovation by increasing the quantity and quality of compost using EM4 (effective microorganism) to accelerate the decomposition of organic matter and the ability to provide nutrients for plants. Results: improvement in soil management into compost and compost quality. Community service has been carried out involving TPS3R Darul Aman partners by providing education on making compost. Limitations: No study covers all aspects. Authors are advised to explain research limitations, as well as further studies or future plans. Contribution: The agricultural sector in the use of compost and the lack of TPS3R employees makes the waste management process difficult.
Formulation and Antibacterial Activity Test of Ethanol Extract Gel of Laruna Root (Chromolaena odorata L.) Against Staphylococcus aureus and Propionibacterium acnes St. Rahmadani; Awaluddin, Nurhikma; Awaluddin, Akbar
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2231

Abstract

Background: The formulation of gel preparations from laruna root extract (Chromolaena odorata L.) has been carried out using Na-CMC base accompanied by physical stability tests of the gel preparations. Objectives: to determine the physical stability of the laruna root extract gel preparation and its good concentration against Staphylococcus aureus and Propionibacterium acnes bacteria. Research method: The physical stability of the gel preparation was determined based on observations of changes in color, odor, shape, pH, uniformity, spreadability, and viscosity before and after storage for 6 cycles at temperatures of 4o C and 40oC. The pH test was carried out using a pH meter and viscosity measurements were carried out using a Brokfield viscometer. Results: The results of the study showed that the laruna root extract gel preparation was declared stable in the homogeneity indicator Results: The results showed that the gel preparation of laruna root extract could be said to be stable on homogeneity parameters where there were no solid particles in the preparation. Stable in good spreading power diameter, i.e. formulas 0, I, II, and III have a diameter of no more than 5-7 cm. For the results of measuring the viscosity of the gel preparation of laruna root extract, it is said to be stable because it is not more than 2000-4000 mPaS. For pH measurement, it is said to be stable because it has a pH in accordance with the quality requirements of skin preparations, which is 4.5-8.0. Conclusion: In the antibacterial activity test, a good clear zone result was obtained at a concentration of 0.3%.
Korelasi Antara Kadar Total Flavonoid dan Fenolik dari Ekstrak dan Fraksi Daun Jati Putih (Gmelina Arborea Roxb.) Terhadap Aktivitas Antioksidan: Correlation Between Total Phenolic and Flavonoid Contents of Jati Putih (Gmelina arborea Roxb.) Leaves Extract and Fraction Toward Antioxidant Activity Nur, Syamsu; Sami, Fitriyanti Jumaetri; Awaluddin, Akbar; Afsari, Mutiara Indah Ayu
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 1 (2019): (March 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.042 KB) | DOI: 10.22487/j24428744.2019.v5.i1.12034

Abstract

This experiment aims to determine the correlation of total phenolic and flavonoid content of jati putih leaves fraction (Gmelina arborea Roxb.) towards Antioxidant activity . Sample was extracted by maceration method using ethanol 70% to obtain the ethanol extract (EE), followed by liquid-liquid extraction method to obtain fraction of ethyl acetate (EA) and n-Hexane (EH). The phytochemical screening and determination of total phenolic and flavonoid content were done by colorimetric method. Antioxidant activity were done by DPPH, FRAP and ABTS methods. Phytochemical screening showed positive results for flavonoids, phenolic and saponins. The largest total phenolic content was found on EA (11,59 µg/ml ± 0,3 %b/b EAG) and the largest total flavonoid content was on EA (3,88 µg/ml ± 0,02 %b/b EK). The total phenolic and flavonoid content of Jati putih leaves has a correlation with antioxidant activity. The coefficient correlation of activity on reducingDPPH radical was 56,7% (total of phenolic content) and 57,8% (total of flavonoid content) and on iron reduction power in FRAP method was 99,9% (total of phenolics and flavonoids content). The relationship with the activity in reducing radical ABTS obtained coefficient correlation of 57,0% and 58,1% for total phenolic and flavonoids contents, respectively.
Sosialisasi, Edukasi dan Pemberian Obat Cacing untuk Siswa Kelas VI/A di SD Negeri Pannara” Awaluddin, Nurhikma; Thayeb, Andi Meinar Dwirantisari; Hanfirs, Rahmatia; Awaluddin, Akbar
Journal Of Human And Education (JAHE) Vol. 4 No. 2 (2024): Journal Of Human And Education (JAHE)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jh.v4i2.605

Abstract

Penularan penyakit usus yang disebabkan oleh cacing kebanyakan terjadi pada wilayah yang mempunyai iklim subtropis dan tropis yang memiliki iklim basah dimana kurangnya kesadaran pada masyarakatnya akan menjaga kesehatan dan menghiraukan akan sanitasi lingkungan sekitarnya. Penyakit ini dapat disebarkan oleh telur yang ada pada kotoran manusia yang terdapat pada tanah dan air, oleh karena itu kesadaran akan hidup bersih dan saniter sangat berpengaruh, proses atau pola pembuangan tinja sangat sangat berpengaruh juga dalam penyebaran kecacingan ini. Tinggi angka pencemaran tanah oleh Ascaris yang mencapai hingga >70% dapat juga disebabkan oleh kotoran yang dibuang di sembarang tempat seperti di semak-semak atau sekitar rumah dekat dengan tempat tinggal. Peningkatan infeksi cacingan di Indonesia terus meningkat seiring waktu, terutama pada anak-anak. Selain pemerintah, peran guru dan orang tua sangatlah penting untuk memberi pemahaman atau pengetahuan mengenai penyakit cacingan agar lebih disiplin. Adapun tujuan pengabdian masyarakat ini adalah untuk memberikan pemahaman kepada siswa kelas VI/A SD N Pannara tentang bahaya cacingan dan cara pencegahannya serta Pemberian Obat Cacing.
Co-Authors Abdul Malik, Fhahri Mubarak Afsari, Mutiara Indah Ayu Aksa, Rahmad Arisah, Arisah Fitriyanti Jumaetri Sami Hanfirs, Rahmatia Hapiwaty, Saldi Ismail , Ismail Khairi, Nur Khairuddin - Maulita Indrisari, Maulita Muslimin, Lukman Nurhikma Awaluddin Pranata, Andriy RR. Ella Evrita Hestiandari Sitti Rahimah St. Rahmadani Syamsu Nur, Syamsu Thayeb, Andi Meinar Dwirantisari Wahyuddin, Nurzadrina