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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Penelitian Pendidikan IPA (JPPIPA) Media Farmasi JURNAL FARMASIMED (JFM) Amalee: Indonesian Journal of Community Research & Engagement Yumary: Jurnal Pengabdian kepada Masyarakat Journal Of Human And Education (JAHE) Jurnal Medika: Medika Jurnal Kefarmasian Indonesia
Awaluddin, Akbar
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Edukasi Siswa melalui Pengenalan Profesi Apoteker pada Program Kelas Inspirasi di SDN Parinring Makassar Awaluddin, Nurhikma; Awaluddin, Akbar
Amalee: Indonesian Journal of Community Research and Engagement Vol 4 No 1 (2023): Amalee: Indonesian Journal of Community Research and Engagement
Publisher : LP2M INSURI Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/amalee.v4i1.2502

Abstract

Pharmacists are the source of information about drugs, but many people still need to familiarize themselves with the pharmacist profession. This causes problems for children as well as adults who lack knowledge about medicines in children, which can lead to drug abuse. This activity aims to educate elementary school students about the introduction of the pharmacist profession, an introduction to drugs, and to foster curiosity about the pharmacist profession from an early age. This activity was carried out at SD Negeri Parinring, Kec: Manggala, Makassar, with 35 participants from grade 6 elementary school students. The Participatory Rural Appraisal (PRA) model is used in community service activities, promoting community empowerment to participate. The action begins with an introduction to material delivered by pharmacists. After that, sing the pharmacist's jingle, and give questions to test the extent of drug knowledge possessed by elementary school students, the results of this community service, especially at SD Negeri Parinring, Kec. Manggala, Makassar can increase understanding and drug awareness early to minimize unwanted side effects and become an agent of change who can explain the confusion of drug information circulating among students.
Efektivitas Ekstrak Daun Kelor (Moringa oleifera L.) Untuk Ulkus Peptikum Pada Tikus Putih (Rattus norvegicus) Yang Diinduksi Aspirin Indrisari, Maulita; Khairi, Nur; Muslimin, Lukman; Awaluddin, Akbar; Arisah, Arisah
Media Farmasi XXX Vol 19, No 1 (2023)
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar, Kementerian Kesehatan RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v19i1.3292

Abstract

Effectiveness of Moringa Leaf Extract (Moringa oleifera L.) for Peptic Ulcuses In Aspirine-Induced White Rats (Rattus norvegicus)Moringa (Moringa oleifera L). is a plant that is known for its multipurpose, nutrient-dense, and medicinal properties. Moringa leaves contain flavonoid compounds, namely β-sitosterol which can reduce ulcers in the stomach. This research used 15 male white rats divided into 5 groups, namely the normal group, CMC Na (Negative), ranitidine (Positive), and treatment with extract doses of 100 and 300 mg/kg BW. Test animals were induced by aspirin at a dose of 500 mg/kg for 7 days, then given treatment for 7 days, except for the normal group. On the 15th day, all groups were sacrificed, then the gastric organs were visually observed, and the ulcer index was measured. the observations it was found that the administration of the extract at a dose of 300 mg/kgBB decreased the number of ulcers compared to the positive control group (p>0.05). The extract dose of 300 mg/kg BW reduces the number of aspirin-induced ulcer diameters. The results of statistics with Kruskall-Wallis, there was a significant difference after treatment (p<0.05), but there was no significant difference between groups (p>0.05). Ethanol extract of Moringa leaves at a dose of 300 mg/kgBB can be gastroprotective in aspirin-induced male white rats.Keyword: Moringa leaves, gastroprotective, gastric ulcer, aspirinKelor (Moringa oleifera L).merupakan tanaman yang dikenal multi guna, padat akan nutrisi dan bermanfaat sebagai obat. Daun kelor mengandung senyawa flavonoid, yakni β-sitosterol yang dapat mengurangi tukak pada lambung. Penelitian ini menggunakan tikus putih jantan sebanyak 15 ekor yang dibagi dalam 5 kelompok yaitu kelompok normal, Na CMC (Negatif), ranitidine (Positif), dan perlakuan dengan dosis  ekstrak 100 dan 300 mg/kgBB. Hewan uji di induksi aspirin dosis 500 mg/kgBB selama 7 hari, kemudian diberi pengobatan selama 7 hari, kecuali kelompok normal. Pada hari ke-15 semua kelompok dikorbankan kemudian diamati organ lambung secara visual diukur indeks tukak. Dari hasil pengamatan diketahui bahwa pemberian ekstrak dosis 300 mg/kgBB terjadi penurunan jumlah tukak dibandingkan dengan kelompok kontrol positif  (p>0,05). Dosis ekstrak 300 mg/kgBB memberikan efek penurunan jumlah diameter tukak akibat induksi aspirin. Berdasarkan hasil perhitungan dengan Kruskall-Wallis menunjukkan adanya perbedaan yang signifikan setelah perlakuan (p<0,05), namun tidak menunjukkan perbedaan signifikan antar kelompok (p>0,05). Ekstrak etanol daun kelor dengan dosis 300 mg/kgBB memiliki kemampuan sebagai gastroprotektif pada tikus putih  jantan yang diinduksi aspirin.Keyword : Daun kelor, gastroprotektif, tukak lambung, aspirin
Pengaruh Fraksi Daun Asam Jawa (Tamarindus indica L.) terhadap Fungsi Hati dan Ginjal Tikus Diinduksi Parasetamol Rahimah, Sitti; Awaluddin, Akbar; Wahyuddin, Nurzadrina
Jurnal Kefarmasian Indonesia VOLUME 12, NOMOR 2, AGUSTUS 2022
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v0i0.5955

Abstract

Liver and kidneys play a role in the metabolism and excretion of substances that enter the body, they become targets for toxicity from xenobiotics and other chemicals including drugs. Exogenous antioxidants are needed to overcome and prevent oxidative stress. Fraction of tamarind leaf extract (Tamarindus indica L) has antioxidant activity, it has the potential to protect the body from free radicals. This study aimed to determine the effect of giving tamarind leaf fractions on AST, ALT and creatinine levels in rats (Rattus norvegicus) induced with paracetamol. Experimental animals were divided into 4 groups. Group I was given paracetamol induction (negative control), group II was given the ethyl acetate fraction and induced paracetamol, group III was given the n-hexane fraction and induced paracetamol, and group IV was without treatment (positive control). Statistical analysis using One Way Anova test and LSD (Post Hoc) showed that the ethyl acetate fraction was not significantly different (p-value >0.05) with the positive control group and the n-hexane fraction group, but significantly different from the negative control group (p -value
Edukasi TPS 3R Darul Aman dan Masyarakat dalam Optimasi Pembuatan Pupuk Kompos di Pondok Pesantren Darul Aman, Gombara, Makassar, Sulawesi Selatan Abdul Malik, Fhahri Mubarak; Khairuddin, Khairuddin; Aksa, Rahmad; Awaluddin, Akbar; Hapiwaty, Saldi; Ismail , Ismail; Azwar, Muhammad; Pranata, Andriy
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 3 (2024): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v4i3.2603

Abstract

Purpose: Helping TPS 3R partners to solve the problem of managing waste into compost is efficient and effective. Methodology: carried out at TPS 3R Darul Aman, method of implementing innovation by increasing the quantity and quality of compost using EM4 (effective microorganism) to accelerate the decomposition of organic matter and the ability to provide nutrients for plants. Results: improvement in soil management into compost and compost quality. Community service has been carried out involving TPS3R Darul Aman partners by providing education on making compost. Limitations: No study covers all aspects. Authors are advised to explain research limitations, as well as further studies or future plans. Contribution: The agricultural sector in the use of compost and the lack of TPS3R employees makes the waste management process difficult.
Formulation and Antibacterial Activity Test of Ethanol Extract Gel of Laruna Root (Chromolaena odorata L.) Against Staphylococcus aureus and Propionibacterium acnes St. Rahmadani; Awaluddin, Nurhikma; Awaluddin, Akbar
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2231

Abstract

Background: The formulation of gel preparations from laruna root extract (Chromolaena odorata L.) has been carried out using Na-CMC base accompanied by physical stability tests of the gel preparations. Objectives: to determine the physical stability of the laruna root extract gel preparation and its good concentration against Staphylococcus aureus and Propionibacterium acnes bacteria. Research method: The physical stability of the gel preparation was determined based on observations of changes in color, odor, shape, pH, uniformity, spreadability, and viscosity before and after storage for 6 cycles at temperatures of 4o C and 40oC. The pH test was carried out using a pH meter and viscosity measurements were carried out using a Brokfield viscometer. Results: The results of the study showed that the laruna root extract gel preparation was declared stable in the homogeneity indicator Results: The results showed that the gel preparation of laruna root extract could be said to be stable on homogeneity parameters where there were no solid particles in the preparation. Stable in good spreading power diameter, i.e. formulas 0, I, II, and III have a diameter of no more than 5-7 cm. For the results of measuring the viscosity of the gel preparation of laruna root extract, it is said to be stable because it is not more than 2000-4000 mPaS. For pH measurement, it is said to be stable because it has a pH in accordance with the quality requirements of skin preparations, which is 4.5-8.0. Conclusion: In the antibacterial activity test, a good clear zone result was obtained at a concentration of 0.3%.
Peran Apoteker Dalam Edukasi Obat Untuk Lansia di Desa Belabori Kab. Gowa Awaluddin, Nurhikma; Basir, Nasrawati; Sadsyam, Sriyanty; Awaluddin, Akbar
Jurnal Medika: Medika Vol. 4 No. 3 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/c3qm7k08

Abstract

Di Indonesia, populasi usia lanjut terus meningkat seiring dengan tingginya angka harapan hidup. Menurut Badan Pusat Statistik, jumlah penduduk lansia di Indonesia pada tahun 2024 diperkirakan mencapai lebih dari 26 juta orang. Lansia sering kali menghadapi berbagai tantangan kesehatan yang kompleks, termasuk penyakit kronis seperti diabetes, hipertensi, dan gangguan jantung. Selain itu, mereka juga cenderung menggunakan beberapa jenis obat secara bersamaan, yang dikenal sebagai polifarmasi. Polifarmasi dapat meningkatkan risiko terjadinya efek samping, interaksi antar obat, serta kesalahan penggunaan obat, yang semuanya dapat berdampak negatif pada kesehatan lansia. Dalam konteks ini, peran apoteker menjadi sangat vital. Apoteker memiliki pengetahuan mendalam tentang farmakologi, termasuk mekanisme kerja obat, interaksi obat, dan efek samping yang mungkin terjadi. Dengan pengetahuan ini, apoteker dapat memberikan edukasi yang tepat kepada lansia mengenai cara penggunaan obat yang aman dan efektif. Edukasi ini meliputi informasi mengenai dosis yang benar, waktu yang tepat untuk mengonsumsi obat, serta tanda-tanda efek samping yang perlu diwaspadai. Selain itu, apoteker juga dapat membantu lansia dalam memahami pentingnya mematuhi regimen pengobatan yang telah ditentukan oleh dokter, sehingga dapat mencegah komplikasi yang lebih serius. Pemeriksaan kesehatan secara berkala juga merupakan aspek penting dalam pengelolaan kesehatan lansia. Melalui pemeriksaan rutin, masalah kesehatan dapat terdeteksi lebih awal, sehingga penanganan yang tepat dapat dilakukan. Apoteker dapat berkontribusi dalam hal ini dengan mengedukasi masyarakat tentang pentingnya pemeriksaan kesehatan dan bagaimana cara mengakses layanan kesehatan yang ada. Dengan memberikan informasi yang akurat dan mudah dipahami, apoteker dapat memberdayakan lansia untuk mengambil keputusan yang lebih baik terkait kesehatan mereka.
Korelasi Antara Kadar Total Flavonoid dan Fenolik dari Ekstrak dan Fraksi Daun Jati Putih (Gmelina Arborea Roxb.) Terhadap Aktivitas Antioksidan: Correlation Between Total Phenolic and Flavonoid Contents of Jati Putih (Gmelina arborea Roxb.) Leaves Extract and Fraction Toward Antioxidant Activity Nur, Syamsu; Sami, Fitriyanti Jumaetri; Awaluddin, Akbar; Afsari, Mutiara Indah Ayu
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 1 (2019): (March 2019)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.042 KB) | DOI: 10.22487/j24428744.2019.v5.i1.12034

Abstract

This experiment aims to determine the correlation of total phenolic and flavonoid content of jati putih leaves fraction (Gmelina arborea Roxb.) towards Antioxidant activity . Sample was extracted by maceration method using ethanol 70% to obtain the ethanol extract (EE), followed by liquid-liquid extraction method to obtain fraction of ethyl acetate (EA) and n-Hexane (EH). The phytochemical screening and determination of total phenolic and flavonoid content were done by colorimetric method. Antioxidant activity were done by DPPH, FRAP and ABTS methods. Phytochemical screening showed positive results for flavonoids, phenolic and saponins. The largest total phenolic content was found on EA (11,59 µg/ml ± 0,3 %b/b EAG) and the largest total flavonoid content was on EA (3,88 µg/ml ± 0,02 %b/b EK). The total phenolic and flavonoid content of Jati putih leaves has a correlation with antioxidant activity. The coefficient correlation of activity on reducingDPPH radical was 56,7% (total of phenolic content) and 57,8% (total of flavonoid content) and on iron reduction power in FRAP method was 99,9% (total of phenolics and flavonoids content). The relationship with the activity in reducing radical ABTS obtained coefficient correlation of 57,0% and 58,1% for total phenolic and flavonoids contents, respectively.
Sosialisasi, Edukasi dan Pemberian Obat Cacing untuk Siswa Kelas VI/A di SD Negeri Pannara” Awaluddin, Nurhikma; Thayeb, Andi Meinar Dwirantisari; Hanfirs, Rahmatia; Awaluddin, Akbar
Journal Of Human And Education (JAHE) Vol. 4 No. 2 (2024): Journal Of Human And Education (JAHE)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jh.v4i2.605

Abstract

Penularan penyakit usus yang disebabkan oleh cacing kebanyakan terjadi pada wilayah yang mempunyai iklim subtropis dan tropis yang memiliki iklim basah dimana kurangnya kesadaran pada masyarakatnya akan menjaga kesehatan dan menghiraukan akan sanitasi lingkungan sekitarnya. Penyakit ini dapat disebarkan oleh telur yang ada pada kotoran manusia yang terdapat pada tanah dan air, oleh karena itu kesadaran akan hidup bersih dan saniter sangat berpengaruh, proses atau pola pembuangan tinja sangat sangat berpengaruh juga dalam penyebaran kecacingan ini. Tinggi angka pencemaran tanah oleh Ascaris yang mencapai hingga >70% dapat juga disebabkan oleh kotoran yang dibuang di sembarang tempat seperti di semak-semak atau sekitar rumah dekat dengan tempat tinggal. Peningkatan infeksi cacingan di Indonesia terus meningkat seiring waktu, terutama pada anak-anak. Selain pemerintah, peran guru dan orang tua sangatlah penting untuk memberi pemahaman atau pengetahuan mengenai penyakit cacingan agar lebih disiplin. Adapun tujuan pengabdian masyarakat ini adalah untuk memberikan pemahaman kepada siswa kelas VI/A SD N Pannara tentang bahaya cacingan dan cara pencegahannya serta Pemberian Obat Cacing.
Evaluasi Penggunaan Antibiotik pada Pasien Anak Infeksi Saluran Akut menggunakan Metode ATC/DDD Fajriansyah; Awaluddin, Akbar; Welly; Zulfahmidah
Jurnal Penelitian Pendidikan IPA Vol 9 No 12 (2023): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i12.6280

Abstract

The use of antibiotics needs to be monitored because it is known that excessive use of antibiotics can increase resistance in the community and this has become a focus both nationally and globally. This study aims to evaluate the use of antibiotics in patients with acute respiratory infection at Hasanuddin University Hospital using the ATC/ DDD analysis method. The research design used a cross-sectional study design with retrospective data collection. The sample in this study was patient medical record data from January-December 2021, taken from total sampling and met the inclusion and exclusion criteria. Descriptive statistics are used to present and analyze data. Evaluation of the use of antibiotics by quantitative methods ATC/DDD (Anatomical Therapeutic Chemical (ATC)/Defined Daily Dose (DDD), DDD/1000/ patient/day. The results showed that the most widely used antibiotic was ampicillin (280 mg) 32.96 DDD/1000 patients/day and the lowest was cefadroxil (150 mg) 1.45 DDD/1000 patients/day. Antibiotics with the highest DDD / 100-patient days value and exceeding the WHO DDD standard were ampicillin antibiotics from the penicillin group with a DDD / 100 patient-day value of 32.96 DDD /100 patient-days.
Co-Authors Abdul Malik, Fhahri Mubarak Afsari, Mutiara Indah Ayu Aksa, Rahmad Arisah, Arisah Fitriyanti Jumaetri Sami Hanfirs, Rahmatia Hapiwaty, Saldi Ismail , Ismail Khairi, Nur Khairuddin - Maulita Indrisari, Maulita Muslimin, Lukman Nasrawati Basir Nurhikma Awaluddin Pranata, Andriy RR. Ella Evrita Hestiandari Sadsyam, Sriyanty Sitti Rahimah, Sitti St. Rahmadani Syamsu Nur, Syamsu Thayeb, Andi Meinar Dwirantisari Wahyuddin, Nurzadrina Welly Zulfahmidah