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POTENSI EKSTRAK DAUN TANAMAN KARAMUNTING (Melastoma malabathricum L.) DI DAERAH KALIMANTAN SEBAGAI ANTIBAKTERI Staphylococcus aureus Niah, Rakhmadhan; Baharsyah, Riki Nirwan
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.285 KB)

Abstract

The year 2008 recorded the death toll reached 16,769 soul due to infection. Infection is one of the diseases caused by bacteria or parasites. Staphylococcus aureus is one of the bacteria causes infection of the skin that is often the case in Indonesia. Staphylococcus aureus bacterial infection can be treated naturally, one of the plants that can be utilized is plant karamunting. Plant leaf karamunting (Melastoma malabathricum l.) contain flavonoids and alkaloids that have activity as antibacterial. The purpose of this research is to know the power of drag karamunting folium of extract against the growth of Staphylococcus aureus. In vitro studies were conducted with diffusion agar method. The extraction of leaf maceration method done with karamunting solvent ethanol 96%. Concentration of karamunting folium of extract used are: 25%, 50%, 75%, and 100%. Microbiology research results indicate that karamunting folium of extract have drag against the growth of bacteria Staphylococcus aureus with extract concentration 50% yield of 5.34 mm; the concentration of extract 75% of 9.40 mm; the concentration of extract 100% of 12.43 mm.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KULIT PISANG KEPOK MENTAH SECARA IN VITRO Ariani, Novia; Niah, Rakhmadhan
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.664 KB) | DOI: 10.51352/jim.v5i2.270

Abstract

The incidence of infections in the gastrointestinal tract is increasing every year. Some bacteria that often cause infections in the gastrointestinal tract are Salmonella typhi, which is a bacterium that causes typhoid fever, and Shigella dysenteriae which is a bacterium that causes dysentery. Handling of infection can only be done by using antibiotics. Improper use of antibiotics can lead to resistance, so it is necessary to look for alternative treatments that come from nature to overcome resistance levels. One of them is raw Kepok banana peel (Musa paradisiaca formatypica) which has secondary metabolites such as flavonoids, alkaloids, tannins, and saponins, where these compounds have many antibacterial activities unknown to the public. This research was an experimental research. The extraction method was using the maceration method with 96% ethanol solvent. Antibacterial activity test for Salmonella typhi and Shigella dysenteriae was using diffusion method therefore the wells were divided into 7 treatment groups, namely extract concentration 0.3125%; 0.625%; 1.25%; 2.5%; 5.0%; positive control (Chloramphenicol dose 30 mg / ml for Salmonella typhi, Ciprofloxacin dose 100 mg / ml for Shigella dysenteriae), and negative control (ethanol 96%). The diameter of the inhibitory zone formed was then measured using a caliper. From the results of the research that has been done, it was found that the ethanol extract of raw Kepok banana peel (Musa paradisiaca forma typica) had inhibitory effect on the growth of Salmonella typhi and Shigella dysenteriae bacteria with the highest inhibition zone diameter of 11.36 mm and the lowest 6.45 mm for Salmonella typhi, and the highest inhibition zone for Shigella dysenteriae was 17.99 mm and the lowest was 15.13 mm. The minimum concentration of banana skin ethanol extract which had inhibitory power was 0.3125%.
KEMAMPUAN PENGHAMBATAN RADIKAL BEBAS HAND SANITIZER EKSTRAK METANOL DAUN SEPAT(Mitragynaspeciosa) Niah, Rakhmadhan; Ariani, Novia
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.126 KB) | DOI: 10.51352/jim.v6i1.314

Abstract

Leaves Sepat (Mitragynaspeciosa) is a plant of Kalimantan. These plants are often used traditionally to reduce blood sugar and antibacterial. The effectiveness is related with strong antioxidant activity in flavonoid compounds. Flavonoid compounds work through the mechanism of capturing free radicals, reducing oxidative stress. The purpose of this study was to measure the percentage of free radical inhibition in the hand sanitizer of methanol extract of leaves Sepat (Mitragynaspeciosa). Sample extraction by maceration method using methanol. Qualitative analysis of chemical compounds with certain eluents using Thin Layer Chromatography (TLC). The antioxidant activity test using the DPPH immersion method (1,1-Diphenyl-2-picryl Hidrazil) measured absorption at a wavelength of 517 nm. The largest percentage of free radical inhibition was obtained in a hand sanitizer concentration of 80 ppm, which is 51.07 ppm.
FORMULASI DAN EVALUASI GEL HAND SANITIZER DARI MINYAK ATSIRI BUNGA LILI (Lilium auratum) Febrianti, Dwi Rizki; Kumalasari, Eka; Niah, Rakhmadhan; Ariani, Novia; Supomo, Supomo; Sandi, Dita Ayulia Dwi
Jurnal Pharmascience Vol 11, No 1 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i1.13822

Abstract

Minyak atsiri bunga lili (lilium auratum) dapat berpotensi sebagai antibakteri dengan memformulasikan dalam bentuk sediaan gel hand sanitizer. Tujuan penelitian ini adalah untuk menentukan sediaan gel antiseptik (Hand sanitizer) minyak atsiri bunga lili dengan berbagai konsentrasi gelling agent carbopol 940 yang mempunyai sifat fisik yang baik dan memenuhi syarat. Carbopol 940 divariasikan dengan konsentrasi 0,667 % dan 1,334% dari total formula. Penelitian ini menggunakan metode eksperimental. Formula diuji sifat fisiknya, seperti uji organoleptis, pH, homogenitas, daya lekat dan daya sebar. Hasil penelitian menunjukkan dari kedua formula dengan variasi konsentrasi gelling agent carbopol 940 yaitu 0,667 % dan 1,334% memenuhi syarat uji sifat fisik. Didapatkan hasil formula yang mempunyai sifat fisik yang memenuhi standar uji sifat fisik adalah formula II dengan konsentrasi Carbopol 940 1,334%. Kata Kunci : Lilium Auratum, Hand Sanitizer, Carbopol 940, Uji Sifat Fisik, Antibakteri The essential oil of lili (Lilium auratum) can potentially be antibacterial by formulating in the form of hand sanitizer gel preparations. This study is to determine the preparation of antiseptic gel (Hand sanitizer) of lilies essential oil with various concentrations of gelling agent carbophol 940 which has good physical properties and qualifies. Carbophol 940 with a variation in concentration of 0.667% and 1.334% with experimental methods conducted trials on formulations so that a product of hand sanitizer gel preparations of lilies essential oil that has good physical properties and qualifies. The results of the research showed that from the two formulas with variations in the concentration of the gelling agent Carbopol 940, namely 0.667% and 1.334%, it met the requirements. The resulting formula which had good physical properties was formula II with the amount of Carbopol 1.334%.
Penggunaan Teknologi Tepat Guna Dalam Pengolahan Produk Abon Ikan Di Kelurahan Alalak Utara: Indonesia Prihandiwati, Erna; Niah, Rakhmadhan
Jurnal Pengabdian Kepada Masyarakat (MEDITEG) Vol. 9 No. 2 (2024): Jurnal Pengabdian Kepada Masyarakat (MEDITEG)
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat (P3M) Politeknik Negeri Tanah Laut (Politala)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34128/mediteg.v9i2.282

Abstract

Kelurahan Alalak Utara, Kecamatan Banjarmasin Utara, Kota Banjarmasin, memiliki potensi besar dalam pengembangan produk pangan olahan berbasis ikan, terutama abon ikan, karena keberadaan penggerak tambak ikan di wilayah tersebut. Melimpahnya ikan patin di daerah ini memberikan dampak positif bagi masyarakat, mengingat ikan patin digemari karena harganya yang terjangkau dan cita rasanya yang khas. Kandungan gizi ikan patin, seperti protein (17 gram per 100 gram), lemak (6,5 gram), kalsium, fosfor, zat besi, kalium, beta karoten, dan niasin (vitamin B3), menjadikannya bahan baku yang potensial untuk produk olahan. Namun, pemanfaatan ikan patin sebagai produk olahan, seperti abon ikan, masih perlu dikembangkan. Kurangnya pengetahuan masyarakat terkait pengolahan, pengemasan, dan pemasaran menjadi kendala utama.  Kegiatan Program Pengabdian kepada Masyarakat bertujuan untuk mengembangkan usaha pengolahan abon ikan melalui penerapan teknologi tepat guna dan diversifikasi produk olahan. Metode yang digunakan meliputi pelatihan, pendampingan, dan penerapan teknologi. Hasil kegiatan menunjukkan peningkatan pengetahuan dan keterampilan masyarakat dalam pengolahan abon ikan serta penguatan usaha lokal. Kesimpulan menunjukkan bahwa program ini berkontribusi pada optimalisasi potensi lokal dan pemberdayaan masyarakat melalui inovasi produk olahan ikan.
Aktivitas Baccaurea motleyana Mull.Arg. terhadap Salmonella thypi Febrianti, Dwi Rizki; Aryzki, Saftia; Khadijah, Maulida; Kumalasari, Eka; Niah, Rakhmadhan
Jurnal Pharmascience Vol 11, No 2 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.16498

Abstract

Penyakit tifus adalah gangguan pada sistem pencernaan yang menyerang bagian usus halus dan terkadang dapat mempengaruhi aliran darah, kantong empedu, limfa, dan hati. Penyebab utama tifus adalah aktivitas bakteri Salmonella thypi, bakteri ini mampu mengontaminasi makanan ataupun minuman yang tidak terjaga sanitasinya. Baccaurea motleyana Mull.Arg memiliki kandungan senyawa antibakteri, diantaranya golongan flavonoid, saponin, dan tanin. Penelitian ini bertujuan untuk membuktikan aktivitas ekstrak daun rambai dalam menghambat S. thypi. Penelitian ini menggunakan metode ekstraksi maserasi dan uji antibakteri menggunakan metode difusi sumuran menggunakan nutrien agar (NA). Ekstraksi dengan maserasi dilakukan menggunakan pelarut etanol 70%. Kelompok perlakuan pada penelitian ini menggunakan seri  konsentrasi ekstrak 10%, 20%, 30%, dan kontrol negatif (water for injection) dengan tiga kali pengulangan. Ukuran diameter zona bening yang terbentuk diukur menggunakan jangka sorong digital. Hasil penelitian menunjukkan bahwa ekstrak daun rambai memiliki efek penghambatan terhadap pertumbuhan bakteri S. thypi. Rerata zona hambat dari ekstrak daun rambai dengan konsentrasi 10%, 20%, dan 30% masing-masing adalah 14,1 mm; 18,8 mm; dan 23,13 mm, sehingga dapat disimpulkan bahwa ekstrak daun B. motleyana memiliki aktivitas terhadap bakteri S. thypi. Kata Kunci: Antibakteri,  Zona Bening, Daun Rambai,  Difusi Padat, Salmonella thypi Typhoid disease is a disorder of the digestive system that attacks parts of the small intestine and can sometimes affect blood flow, gallbladder, lymph, and liver. The main cause of typhus is the activity of Salmonella thypi bacteria, this bacterium is able to contaminate food or drinks that are not maintained sanitation. Baccaurea motleyana Mull.Arg contains antibacterial compounds, including flavonoids, saponins, and tannins. This study aims to prove the activity of rambai leaf extract in inhibiting S. thypi. This study uses the maceration extraction method and antibacterial test using the well diffusion method using agar nutrients (NA). Extraction by maceration is carried out using a 70% ethanol solvent. The treatment group in this study used a series of 10%, 20%, 30% extract concentrations, and negative control (water for injection) with three repetitions. The size of the diameter of the formed clear zone is measured using a digital caliper. The results showed that rambai leaf extract had an inhibitory effect on the growth of S. thypi bacteria. The average inhibition zone of rambai leaf extract with concentrations of 10%, 20%, and 30% was 14.1 mm, respectively; 18.8 mm; and 23.13 mm, so it can be concluded that B. motleyana leaf extract has activity against S. thypi bacteria.
FORMULASI DAN EVALUASI FISIK SEDIAAN TABLET NANOPARTIKEL EKSTRAK DAUN DADANGKAK (Hydrolea spinosa L.) Niah, Rakhmadhan; Wahyuono, Subagus; Prihandiwati, Erna
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jdkpqw89

Abstract

The utilization of traditional medicines offers a safer alternative for treatment, particularly regarding side effects and toxicity. One herbal plant known for its antioxidant activity is dadangkak leaves (Hydrolea spinosa L.), containing flavonoids, polyphenols, and tannins. Ethanolic extracts of dadangkak leaves with antioxidant potential need development into tablet dosage forms. This study aims to determine the optimal formula for nanoparticle tablets containing dadangkak leaf extract. The extract was obtained via maceration using 96% technical ethanol, followed by evaporation to produce a thick extract. Nanoparticles were prepared by mixing the extract with 96% technical ethanol, distilled water, a chitosan solution in acetic acid, and a NaTTP solution. Particle size was analyzed using a Particle Size Analyzer (PSA). Tablet formulations involved varying concentrations of Na alginate and Avicel PH 102, using direct compression. Results showed that Na alginate and Avicel PH 102 concentrations affected tablet physical properties. Avicel PH 102 increased hardness and disintegration time, while Na alginate increased friability. Based on evaluations, formula 2 was determined to be the best.
Pemberdayaan Kelompok Budidaya Ikan di Kelurahan Sungai Lulut melalui Teknologi Pembuatan Pakan Herbal Daun Kelor dan Edukasi Ikan sebagai Nutraseutikal Pencegah Stunting: The Driving Force of Fish Farming Group in Sungai Lulut Village through the Technology of Herbal Moringa Leaf Feed Production and Education on Fish as a Nutraceutical to Prevent Stunting Niah, Rakhmadhan; Prihandiwati, Erna; Aisyah, Noor; Dharmaji, Deddy
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 11 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i11.8270

Abstract

The issue "Jaya Makmur" is low quality and quantity of fish production, primarily due to reliance on suboptimal instant feed and insufficient fish utilization to combat stunting in Sungai Lulut. This activity aims to enhance fish production quality and quantity, processing herbal feed from moringa leaves, and educating the community to help reduce stunting. The method of this activity includes socialization, training in producing herbal feed and eco-friendly mixing tools, application of technology, assistance, evaluation, utilization of unused land, and continuous monitoring to enhance production and establish distribution partnerships, all while educating about stunting.The success of this program is reflected in the improvement of partner skills in making natural feed, feed management, and the production of fish-based nuggets and meatballs for complementary feeding (MPASI). The challenge currently faced is that many fish farmers still rely on instant feed, so further efforts are needed to encourage the transition to herbal feed.
UPAYA PENCEGAHAN DAN PENANGAN STUNTING MELALUI EDUKASI DAN PENGOLAHAN PANGAN “PANTING” PATIN CEGAH STUNTING DI DESA TATAH BANGKAL Aisyah, Noor; Riko Nugroho, Muhammad; Putri, Aisya Novrida; Norhalisa; Wandarie, Indah; Andriyani, Novita; Rahma Syari, Aulia; Lathifah, Nor; Dhiya Kamila, Marsa; Niah, Rakhmadhan
Jurnal Bakti untuk Negeri Vol 5 No 1 (2025): Jurnal Bakti Untuk Negeri
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/h37dx678

Abstract

Stunting is a condition of toddlers with short stature, a chronic nutritional problem that usually occurs during the first 1000 days of life (HPK). Stunting is characterized by a toddler's length or height that is not in accordance with their age. The number of stunting in children under the age of five is more common in rural areas compared to urban areas, although in general the prevalence has decreased. This difference is caused by various complex factors, including socio-demographic aspects, economic disparities, and unequal access to health services. This activity aims to increase knowledge and processing of catfish nuggets for pregnant women and mothers whose children are indicated as stunting. The implementation method is carried out through education, socialization and distribution of leaflets related to stunting, processing of catfish nuggets and pre-test and post-test evaluations. The results of the activity showed an increase in participants obtained from 27 participants, namely ... before the presentation of the material to ... after the presentation. It is hoped that this activity will motivate participants to reduce stunting rates in Tatatah Village, Bangkal.
PENINGKATAN KESEHATAN ANAK MELALUI LAYANAN Khitanan: PROGRAM PELAYANAN MASYARAKAT DI DESA CAHAYA BARU KABUPATEN BARITO KUALA INDONESIA Alfiannor, M.; Susilo, Yudi Hardi; Ulfah, Maria; Niah, Rakhmadhan; Aisyah, Noor; Riski, Akhmad; Normilawati, Normilawati; Nurjihan, Lu’lu; Kurniawan, Henny; Wahyudi, Wahyudi; Ma’ruf, Muhammad; Wahyuni, Amaliyah; Ariani, Novia; Fawwazi, Muhammad Hafizh Abiyyu Fathin; Yumassik, Abdul Mahmud; Widodo, Arif Nur; Prihandiwati, Erna; Susanto, Yugo; Rustandi, Tedi
Jurnal Bakti untuk Negeri Vol 5 No 1 (2025): Jurnal Bakti Untuk Negeri
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/zb72hw73

Abstract

Background: Child health is essential for human resource development, especially in communities with limited health services. One preventive measure that can be taken to maintain genital hygiene is circumcision. This preventive measure reduces the risk of urinary tract infections and sexually transmitted diseases. However, to carry out child circumcision independently, there are some financial problems in Cahaya Baru Village, Jejangkit District, Barito Kuala Regency. Methods: This activity involved children from Cahaya Baru Village. Participant screening, health instructions, circumcision procedures carried out by medical professionals, post-procedure medication administration, and medication use instructions were all methods used in the implementation. The Indonesian Red Crescent (BSMI) of South Kalimantan, the Barito Kuala District Health Office, the Jejangkit District Health Center, and the Cahaya Baru Village government were involved in this project. Results and discussion: Forty participants successfully received a safe and controlled circumcision procedure. Before the procedure, all participants underwent a screening process and received health instructions. There were no significant complications post-circumcision, and all participants received pain relievers and antibiotics for healing. In addition, DAGUSIBU training increased community understanding of proper drug use. Active participation of various parties ensured that activities ran smoothly and increased synergy in community-based health services. Conclusion: Mass circumcision activities in Cahaya Baru Village showed that multi-sector collaboration-based programs can improve community access to basic health services. This program was successful thanks to participation, trained medical personnel, and health education. Similar efforts are expected to be carried out sustainably to increase the positive effects on community health welfare.