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All Journal Pharmaciana: Jurnal Kefarmasian Cosmogov: Jurnal Ilmu Pemerintahan Pharmascience Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Manuntung Pharmasipha Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Eka Kumalasari
Akademi Farmasi ISFI Banjarmasin
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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AKTIVITAS ANTIFUNGI EKSTRAK ETANOL BATANG BINAHONG (Anredera cordifolia (Tenore) Steen.) TERHADAP Candida albicans SERTA SKRINING FITOKIMIA Kumalasari, Eka; Sulistyani, Nanik
PHARMACIANA Vol 1, No 2: November 2011
Publisher : PHARMACIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.03 KB)

Abstract

Binahong (Anredera cordifolia (Tenore) Steen.) merupakan tanaman yang secara empiris telah digunakan untuk mengobati beberapa penyakit yang disebabkan jamur.Penelitian ini bertujuan untuk mengetahui aktivitas antifungi ekstrak etanol batang Binahong terhadap C. albicans dan mengetahui kandungan kimia dalam ekstrak etanol batang Binahong. Serbuk batang Binahong diekstraksi dengan metode maserasi menggunakan pelarut etanol 70%.Uji antifungi dilakukan dengan metode dilusi cair dengan berbagai konsentrasi ekstrak (85; 86; 87; 88; 89; 90% b/v). Ekstrak dicampur dengan suspensi jamur dalam media CYG dan diinkubasi pada suhu 37ºC selama 18-24 jam untuk menentukan Kadar Hambat Minimum (KHM). Cairan kultur hasil inkubasi digoreskan pada media SDA (Sabouraud Dextrose Agar) untuk menentukan Kadar Bunuh Minimum (KBM). Uji tabung dan kromatografi lapis tipis dilakukan untuk mengetahui golongan senyawa yang terdapat dalam ekstrak etanol batang Binahong. Hasil penelitian menunjukkan bahwa KHM tidak dapat ditentukan karena ekstrak etanol keruh dan berwarna hijau pekat, sedangkan KBM ekstrak etanol batang Binahong terhadap C. albicans adalah 86% b/v. Hasil uji skrining fitokimia dengan uji tabung dan uji kromatografi lapis tipis menunjukkan bahwa batang Binahong mengandung saponin, flavonoid, dan polifenol.
PENETAPAN KADAR SIKLAMAT DALAM SIRUP MERAH YANG DIJUAL DI BANJARMASIN UTARA Hamidah, Marina; Kumalasari, Eka; Musiam, Siska
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 1, No 1 (2016)
Publisher : Akademi Farmasi ISFI Banjarmasin

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Abstract

Bahan tambahan pangan adalah bahan yang ditambahkan ke dalam makanan untuk mempengaruhi sifat ataupun bentuk makanan. Salah satu bahan tambahan pangan adalah pemanis. Pemanis sintetis yang umumnya digunakan industri makanan maupun minuman adalah siklamat. Penggunaan siklamat yang berlebihan akan menyebabkan tumor dan kanker. Codex Alimentarius Commission (CAC) menetapkan bahwa kadar maksimal siklamat yang dapat dikonsumsi oleh tubuh adalah 500 – 3000 mg/kg berat badan. Oleh karena itu, dalam penelitian ini bertujuan untuk menguji kadar siklamat dalam sirup merah yang dijual di Banjarmasin Utara. Identifikasi siklamat menggunakan metode pengendapan dengan pereaksi HCl 10%, BaCl2 10% dan NaNO2 10%, dan pengujian kadar siklamat dilakukan dengan metode gravimetri. Hasil penelitian menunjukkan 6 sampel dari 15 sampel sirup merah yang dijual di Banjarmasin Utara mengandung pemanis siklamat. Kadar siklamat yang didapatkan pada sampel positif diuji dengan metode gravimetri dan didapatkan hasil berturut-turut adalah 46,21 mg/kg; 71,26 mg/kg; 97,86 mg/kg; 74,82 mg/kg; 84,46 mg/kg; dan 105,24 mg/kg berat badan. Hasil tersebut tidak melebihi ambang batas jika dibandingkan dengan kadar maksimal yang ditetapkan oleh CAC, yaitu 500 – 3000 mg/kg berat badan.Kata kunci:  bahan tambahan pangan, pemanis, siklamat, sirup merah, metode gravimetri
The determination of metal content, microbial contamination and dissolution assessment of the ethanol extract of pasak bumi root Nurani, Laela Hayu; Kumalasari, Eka; Zainab, Zainab; Mursyidi, Achmad; Widyarini, Sitarina; Rohman, Abdul
Pharmaciana Vol 7, No 2 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.452 KB) | DOI: 10.12928/pharmaciana.v7i2.6751

Abstract

 The Eurycoma longifoliais bitter therefore, to address this problem, it is prepared in a capsule form. The capsule dosage form  must has  the parameters of good quality, thus expected to increase the potential use of biodiversity and the interest of the community in consuming the medicine from the natural materials. The purpose of this research is to get the capsule product of ethanol extract of the Eurycoma longifolia root of quality through the test of total plate value and yeast yeast contamination, the determination of the metal content of Pb, Hg, Cd and the level of flavonoids released in the capsule dissolution test of ethanol extract Eurycoma longifolia root. The result of this research shows that the dissolution efficiency (DE120) capability of ethanol extract of Eurycoma longifolia root is 81,04±2,38%. Test of heavy metal content in capsule of  of ethanol extract of Eurycoma longifolia root found level of Pb equal to 4,132 ppm and not detected content of Cd and Hg in capsule. This indicates that the capsule meets the requirements set by BPOM RI. Tests for total plate numbers (ALT) and yeast capsule ethanol extract of the E. longifolia root were each obtained data of 70 x 102 colonies / g and 4 x 102 colonies / g. It also shows that the capsules meet the requirements by BPOM RI.
AKTIVITAS ANTIFUNGI EKSTRAK ETANOL BATANG BINAHONG (Anredera cordifolia (Tenore) Steen.) TERHADAP Candida albicans SERTA SKRINING FITOKIMIA Kumalasari, Eka; Sulistyani, Nanik
Pharmaciana Vol 1, No 2 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (143.103 KB) | DOI: 10.12928/pharmaciana.v1i2.524

Abstract

Anredera cordifolia is a plantused as antifungal empirically. This study aims tofind out the antifungal activity of ethanol extract of A. cordifolia stem against C.albicans and to identify the chemical subtance groups of the ethanol extract of A.cordifolia. The A. cordifolia stem was extracted by maceration method using ethanol 70% as solvent. The antifungal assay was done using liquid dilution method with variousconcentrations of (85; 86; 87; 88; 89; 90% w/v). The mixtures of extract and suspensionof C. albicans in CYG (Casein Yeast Glucose) medium and the media were incubated at37ºC for 18-24 hours to determine Minimum Inhibitor Conceration (MIC).Theculturewas streaked on SDA (Sabouraud Dextrose Agar) medium to determineMinimum Fungicidal Conceration (MFC). Chromatographic test and tube test weredone to identify the chemical substances of A. cordifolia extract. The result showed thatthe MIC could not be determined because the extract was brownish and turbid while theMFC of A. cordifolia stem ethanolic extract was 86% w/v. The result of thephytochemical screening with tube test and the thin layer chromatography test showedthat the extract of A. cordifolia stem contained flavonoids, polyphenols, and saponin.
IDENTIFIKASI DAN PENETAPAN KADAR RHODAMIN B DALAM KERUPUK BERWARNA MERAH YANG BEREDAR DI PASAR ANTASARI KOTA BANJARMASIN Kumalasari, Eka
Jurnal Ilmiah Manuntung Vol 1 No 1 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.998 KB) | DOI: 10.51352/jim.v1i1.17

Abstract

Crackers are made from tapioca flour batter mixed with flavorings and colorings, still many outstanding crackers that contain ingredients banned dye Rhodamine B. Rhodamine B is a chemical used for red dye in the textile industry and plastic. Rhodamine B can cause cancer, poisoning, lung irritation, sore eyes, and sore throat. This study aims to identify and determination the levels of Rhodamine B in circulating red crackers Antasari market Banjarmasin.The population is that sold in the red crackers that sold in Antasari market Banjarmasin.. The sampling is technique incidental sampling , that is based on chance, so any population by chance met with researchers can be used as a sample. Identification of Rhodamine B was done by Thin Layer Chromatography (TLC) by using the stationary phase silica GF 254 and mobile phase is elution solvent is n-butanol, ethyl acetate, ammonia (10:4:5). Then detected with a UV lamp 254 nm and 366 nm. While for the determination of levels using Vis spectrophotometry at a wavelength of 544 nm.The results showed that the samples of 6 found one sample containing Rhodamine B, namely samples 5 (cassava crackers matches) and obtained values of 7,25 ± 3,8640 levels mg / kg. Based on these results, Rhodamine B still found in crackers that sold in the market Antasari Banjarmasin.
DYNAMICS THE ZONATION POLICY SYSTEM FOR UPPER SECONDARY STUDENT ADMISSIONS IN KAMPAR DISTRICT RIAU PROVINCE Nurman, Nurman; Kumalasari, Eka; Erlina, Erlina; Yuli, Annisa Rahma
CosmoGov: Jurnal Ilmu Pemerintahan Vol 10, No 1 (2024)
Publisher : Department of Government, FISIP, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cosmogov.v10i1.51151

Abstract

The development of information technology has entered various fields. Utilization of information and telecommunications technology in public services. It is no longer something new for developed countries. Apart from that, there is demand from the public for information which requires the Government to provide public services that suit the needs of the community. Policy implementation is one of the stages of public policy, between policy formation and the policy consequences for the communities it influences. If a policy is inappropriate or cannot reduce the problem that is the target of the policy, then the policy will probably fail even if the policy is implemented very well. Meanwhile, a policy that has been planned very well may also fail if the policy is not implemented well by the policy implementers. The aim of this research is to determine the Policy Dynamics of the Zoning System for Admission of High School Students in Kampar Regency, Riau Province. This research uses a qualitative method with stages including preparing a research design, determining the location and research informants, collecting data, analyzing data, presenting data and drawing conclusions. Research findings show that the school and local government cannot confirm zoning boundaries so that prospective new students cannot register and fail to enter the nearest school even though they are in the zone and end up enrolling in private schools which require a lot of education costs.
ANALISIS BIAYA PASIEN COVID-19 DI RUMAH SAKIT X KOTA BANJARMASIN Aisyah, Noor Aisyah; Aisyah, Noor; Norhilaliyah, Norhilaliyah; Wahyuni, Amaliyah; Kumalasari, Eka; Yumassik, Abdul Mahmud; Illahi, Fitrah Shafran
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1936

Abstract

COVID -19 is designated as an infectious disease that causes an outbreak and causes a public health emergency. COVID-19 causes death and absorbs significant disease costs. The research aims to determine the average cost of inpatient COVID-19 patients at hospitals in the city of Banjarmasin. This research is a descriptive non-experimental study using observational research methods, data was taken retrospectively to provide an overview of the costs of COVID-19 patients. The research sample is data on costs for inpatient COVID-19 patients in March-April 2020 at Hospital x Banjarmasin City with a sample size of 347 treatment episodes. The research results show that the average cost for a COVID-19 patient per episode of treatment is IDR 13,095,609. The total cost of all episodes of care for hospitalized COVID-19 patients is IDR 4,544,176,469. The first largest cost component that absorbs the most costs is the cost of drugs and medical materials amounting to IDR 1,236,714,000 per component with an average of IDR 3,564,017 per episode of care (27.215%). The second largest cost component is room costs, namely IDR 781,624,400 with an average cost of IDR 2,252,520 per treatment episode (17.20).
FORMULASI DAN EVALUASI GEL HAND SANITIZER DARI MINYAK ATSIRI BUNGA LILI (Lilium auratum) Febrianti, Dwi Rizki; Kumalasari, Eka; Niah, Rakhmadhan; Ariani, Novia; Supomo, Supomo; Sandi, Dita Ayulia Dwi
Jurnal Pharmascience Vol 11, No 1 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i1.13822

Abstract

Minyak atsiri bunga lili (lilium auratum) dapat berpotensi sebagai antibakteri dengan memformulasikan dalam bentuk sediaan gel hand sanitizer. Tujuan penelitian ini adalah untuk menentukan sediaan gel antiseptik (Hand sanitizer) minyak atsiri bunga lili dengan berbagai konsentrasi gelling agent carbopol 940 yang mempunyai sifat fisik yang baik dan memenuhi syarat. Carbopol 940 divariasikan dengan konsentrasi 0,667 % dan 1,334% dari total formula. Penelitian ini menggunakan metode eksperimental. Formula diuji sifat fisiknya, seperti uji organoleptis, pH, homogenitas, daya lekat dan daya sebar. Hasil penelitian menunjukkan dari kedua formula dengan variasi konsentrasi gelling agent carbopol 940 yaitu 0,667 % dan 1,334% memenuhi syarat uji sifat fisik. Didapatkan hasil formula yang mempunyai sifat fisik yang memenuhi standar uji sifat fisik adalah formula II dengan konsentrasi Carbopol 940 1,334%. Kata Kunci : Lilium Auratum, Hand Sanitizer, Carbopol 940, Uji Sifat Fisik, Antibakteri The essential oil of lili (Lilium auratum) can potentially be antibacterial by formulating in the form of hand sanitizer gel preparations. This study is to determine the preparation of antiseptic gel (Hand sanitizer) of lilies essential oil with various concentrations of gelling agent carbophol 940 which has good physical properties and qualifies. Carbophol 940 with a variation in concentration of 0.667% and 1.334% with experimental methods conducted trials on formulations so that a product of hand sanitizer gel preparations of lilies essential oil that has good physical properties and qualifies. The results of the research showed that from the two formulas with variations in the concentration of the gelling agent Carbopol 940, namely 0.667% and 1.334%, it met the requirements. The resulting formula which had good physical properties was formula II with the amount of Carbopol 1.334%.
Aktivitas Baccaurea motleyana Mull.Arg. terhadap Salmonella thypi Febrianti, Dwi Rizki; Aryzki, Saftia; Khadijah, Maulida; Kumalasari, Eka; Niah, Rakhmadhan
Jurnal Pharmascience Vol 11, No 2 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.16498

Abstract

Penyakit tifus adalah gangguan pada sistem pencernaan yang menyerang bagian usus halus dan terkadang dapat mempengaruhi aliran darah, kantong empedu, limfa, dan hati. Penyebab utama tifus adalah aktivitas bakteri Salmonella thypi, bakteri ini mampu mengontaminasi makanan ataupun minuman yang tidak terjaga sanitasinya. Baccaurea motleyana Mull.Arg memiliki kandungan senyawa antibakteri, diantaranya golongan flavonoid, saponin, dan tanin. Penelitian ini bertujuan untuk membuktikan aktivitas ekstrak daun rambai dalam menghambat S. thypi. Penelitian ini menggunakan metode ekstraksi maserasi dan uji antibakteri menggunakan metode difusi sumuran menggunakan nutrien agar (NA). Ekstraksi dengan maserasi dilakukan menggunakan pelarut etanol 70%. Kelompok perlakuan pada penelitian ini menggunakan seri  konsentrasi ekstrak 10%, 20%, 30%, dan kontrol negatif (water for injection) dengan tiga kali pengulangan. Ukuran diameter zona bening yang terbentuk diukur menggunakan jangka sorong digital. Hasil penelitian menunjukkan bahwa ekstrak daun rambai memiliki efek penghambatan terhadap pertumbuhan bakteri S. thypi. Rerata zona hambat dari ekstrak daun rambai dengan konsentrasi 10%, 20%, dan 30% masing-masing adalah 14,1 mm; 18,8 mm; dan 23,13 mm, sehingga dapat disimpulkan bahwa ekstrak daun B. motleyana memiliki aktivitas terhadap bakteri S. thypi. Kata Kunci: Antibakteri,  Zona Bening, Daun Rambai,  Difusi Padat, Salmonella thypi Typhoid disease is a disorder of the digestive system that attacks parts of the small intestine and can sometimes affect blood flow, gallbladder, lymph, and liver. The main cause of typhus is the activity of Salmonella thypi bacteria, this bacterium is able to contaminate food or drinks that are not maintained sanitation. Baccaurea motleyana Mull.Arg contains antibacterial compounds, including flavonoids, saponins, and tannins. This study aims to prove the activity of rambai leaf extract in inhibiting S. thypi. This study uses the maceration extraction method and antibacterial test using the well diffusion method using agar nutrients (NA). Extraction by maceration is carried out using a 70% ethanol solvent. The treatment group in this study used a series of 10%, 20%, 30% extract concentrations, and negative control (water for injection) with three repetitions. The size of the diameter of the formed clear zone is measured using a digital caliper. The results showed that rambai leaf extract had an inhibitory effect on the growth of S. thypi bacteria. The average inhibition zone of rambai leaf extract with concentrations of 10%, 20%, and 30% was 14.1 mm, respectively; 18.8 mm; and 23.13 mm, so it can be concluded that B. motleyana leaf extract has activity against S. thypi bacteria.
PERBANDINGAN PELARUT ETANOL-AIR DALAM PROSES EKSTRAKSI DAUN BAWANG DAYAK (Eleutherine palmifolia Linn) TERHADAP AKTIVITAS ANTIOKSIDAN DENGAN METODE DPPH Kumalasari, Eka; Musiam, Siska
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i3.2290

Abstract

The immune system can be damaged by the presence of free radicals. The formation of free radicals must be prevented by antioxidants. Humanes basically do not have antioxidant reserves in their her body, so that when there is exposure to excessive the radicals then the needs body antioxidant intake from the outside. At present it is encouraged the development of antioxidants derived from plants, which are relatively easier to obtain and safe for humans consumption. Potential to antioxidant plants one of them is dayak onion leaves. Dayak onion leaves are a typical plant Borneo Central used by the Dayak tribe as medicine. To get a high active ingredient in dayak onion leaves, it is necessary to optimize the type of maceration solvent. The types of solvents used are water and ethanol. Testing of antioxidant using activities DPPH (2,2-Diphenyl-1-picrylhydrazyl) as a free radical compound. The maximum wavelength of DPPH in this study is at 519 nm. The highest IC50 value was found on dayak onion leaf extract with water solvent which was 58.62 ppm, with ethanol-water solvent of 33.71 ppm, and the smallest with ethanol solvent of 26.98 ppm. Key: antioxydan, Eleutherine palmifolia of leave, DPPH
Co-Authors Achmad Mursyidi Aisyah, Noor Aisyah, Noor Aisyah Amelia, Senya Puteri Ariani, Novia Aryzki, Saftia Erlina Erlina Febrianti, Dwi Rizki Hamidah, Marina Illahi, Fitrah Shafran Khadijah, Maulida Laela Hayu Nurani Ma'ruf, Muhammad Mar'uf, Muhammad Marta Fransiska, Revita Muhammad Hafizh Abiyyu Fathin Fawwazi Muhammad Ma'ruf Nafisa Berliana, Siti Nanang Fakhrudin, Nanang Nanik Sulistyani Nayandra, Faizah Niah, Rakhmadhan Norhilaliyah, Norhilaliyah Normilawati Nour Athiroh Abdoes Sjakoer Nurman Nurman Nurul Jadid Mubarokati Prihandiwati, Erna Purnomo, Dimas Kalinggo Rahayu, Mirenne Anik Sri Riski, Akhmad Rohman, Abdul Sandi, Dita Ayulia Dwi Siska Musiam Subagus Wahyuono Supomo Supomo Wahyuni, Amaliyah Widyarini, Sitarina Yuli, Annisa Rahma Yumassik, Abdul Mahmud Zainab Zainab