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All Journal Pharmaciana: Jurnal Kefarmasian Cosmogov: Jurnal Ilmu Pemerintahan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pharmasipha Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Klinik dan Sains Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Journal of Pharmascience
Eka Kumalasari
Akademi Farmasi ISFI Banjarmasin
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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AKTIVITAS ANTIFUNGI EKSTRAK ETANOL BATANG BINAHONG (Anredera cordifolia (Tenore) Steen.) TERHADAP Candida albicans SERTA SKRINING FITOKIMIA Kumalasari, Eka; Sulistyani, Nanik
PHARMACIANA Vol 1, No 2: November 2011
Publisher : PHARMACIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.03 KB)

Abstract

Binahong (Anredera cordifolia (Tenore) Steen.) merupakan tanaman yang secara empiris telah digunakan untuk mengobati beberapa penyakit yang disebabkan jamur.Penelitian ini bertujuan untuk mengetahui aktivitas antifungi ekstrak etanol batang Binahong terhadap C. albicans dan mengetahui kandungan kimia dalam ekstrak etanol batang Binahong. Serbuk batang Binahong diekstraksi dengan metode maserasi menggunakan pelarut etanol 70%.Uji antifungi dilakukan dengan metode dilusi cair dengan berbagai konsentrasi ekstrak (85; 86; 87; 88; 89; 90% b/v). Ekstrak dicampur dengan suspensi jamur dalam media CYG dan diinkubasi pada suhu 37ºC selama 18-24 jam untuk menentukan Kadar Hambat Minimum (KHM). Cairan kultur hasil inkubasi digoreskan pada media SDA (Sabouraud Dextrose Agar) untuk menentukan Kadar Bunuh Minimum (KBM). Uji tabung dan kromatografi lapis tipis dilakukan untuk mengetahui golongan senyawa yang terdapat dalam ekstrak etanol batang Binahong. Hasil penelitian menunjukkan bahwa KHM tidak dapat ditentukan karena ekstrak etanol keruh dan berwarna hijau pekat, sedangkan KBM ekstrak etanol batang Binahong terhadap C. albicans adalah 86% b/v. Hasil uji skrining fitokimia dengan uji tabung dan uji kromatografi lapis tipis menunjukkan bahwa batang Binahong mengandung saponin, flavonoid, dan polifenol.
PENETAPAN KADAR SIKLAMAT DALAM SIRUP MERAH YANG DIJUAL DI BANJARMASIN UTARA Hamidah, Marina; Kumalasari, Eka; Musiam, Siska
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 1, No 1 (2016)
Publisher : Akademi Farmasi ISFI Banjarmasin

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Abstract

Bahan tambahan pangan adalah bahan yang ditambahkan ke dalam makanan untuk mempengaruhi sifat ataupun bentuk makanan. Salah satu bahan tambahan pangan adalah pemanis. Pemanis sintetis yang umumnya digunakan industri makanan maupun minuman adalah siklamat. Penggunaan siklamat yang berlebihan akan menyebabkan tumor dan kanker. Codex Alimentarius Commission (CAC) menetapkan bahwa kadar maksimal siklamat yang dapat dikonsumsi oleh tubuh adalah 500 – 3000 mg/kg berat badan. Oleh karena itu, dalam penelitian ini bertujuan untuk menguji kadar siklamat dalam sirup merah yang dijual di Banjarmasin Utara. Identifikasi siklamat menggunakan metode pengendapan dengan pereaksi HCl 10%, BaCl2 10% dan NaNO2 10%, dan pengujian kadar siklamat dilakukan dengan metode gravimetri. Hasil penelitian menunjukkan 6 sampel dari 15 sampel sirup merah yang dijual di Banjarmasin Utara mengandung pemanis siklamat. Kadar siklamat yang didapatkan pada sampel positif diuji dengan metode gravimetri dan didapatkan hasil berturut-turut adalah 46,21 mg/kg; 71,26 mg/kg; 97,86 mg/kg; 74,82 mg/kg; 84,46 mg/kg; dan 105,24 mg/kg berat badan. Hasil tersebut tidak melebihi ambang batas jika dibandingkan dengan kadar maksimal yang ditetapkan oleh CAC, yaitu 500 – 3000 mg/kg berat badan.Kata kunci:  bahan tambahan pangan, pemanis, siklamat, sirup merah, metode gravimetri
The determination of metal content, microbial contamination and dissolution assessment of the ethanol extract of pasak bumi root Nurani, Laela Hayu; Kumalasari, Eka; Zainab, Zainab; Mursyidi, Achmad; Widyarini, Sitarina; Rohman, Abdul
Pharmaciana Vol 7, No 2 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.452 KB) | DOI: 10.12928/pharmaciana.v7i2.6751

Abstract

 The Eurycoma longifoliais bitter therefore, to address this problem, it is prepared in a capsule form. The capsule dosage form  must has  the parameters of good quality, thus expected to increase the potential use of biodiversity and the interest of the community in consuming the medicine from the natural materials. The purpose of this research is to get the capsule product of ethanol extract of the Eurycoma longifolia root of quality through the test of total plate value and yeast yeast contamination, the determination of the metal content of Pb, Hg, Cd and the level of flavonoids released in the capsule dissolution test of ethanol extract Eurycoma longifolia root. The result of this research shows that the dissolution efficiency (DE120) capability of ethanol extract of Eurycoma longifolia root is 81,04±2,38%. Test of heavy metal content in capsule of  of ethanol extract of Eurycoma longifolia root found level of Pb equal to 4,132 ppm and not detected content of Cd and Hg in capsule. This indicates that the capsule meets the requirements set by BPOM RI. Tests for total plate numbers (ALT) and yeast capsule ethanol extract of the E. longifolia root were each obtained data of 70 x 102 colonies / g and 4 x 102 colonies / g. It also shows that the capsules meet the requirements by BPOM RI.
AKTIVITAS ANTIFUNGI EKSTRAK ETANOL BATANG BINAHONG (Anredera cordifolia (Tenore) Steen.) TERHADAP Candida albicans SERTA SKRINING FITOKIMIA Kumalasari, Eka; Sulistyani, Nanik
Pharmaciana Vol 1, No 2 (2011): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (143.103 KB) | DOI: 10.12928/pharmaciana.v1i2.524

Abstract

Anredera cordifolia is a plantused as antifungal empirically. This study aims tofind out the antifungal activity of ethanol extract of A. cordifolia stem against C.albicans and to identify the chemical subtance groups of the ethanol extract of A.cordifolia. The A. cordifolia stem was extracted by maceration method using ethanol 70% as solvent. The antifungal assay was done using liquid dilution method with variousconcentrations of (85; 86; 87; 88; 89; 90% w/v). The mixtures of extract and suspensionof C. albicans in CYG (Casein Yeast Glucose) medium and the media were incubated at37ºC for 18-24 hours to determine Minimum Inhibitor Conceration (MIC).Theculturewas streaked on SDA (Sabouraud Dextrose Agar) medium to determineMinimum Fungicidal Conceration (MFC). Chromatographic test and tube test weredone to identify the chemical substances of A. cordifolia extract. The result showed thatthe MIC could not be determined because the extract was brownish and turbid while theMFC of A. cordifolia stem ethanolic extract was 86% w/v. The result of thephytochemical screening with tube test and the thin layer chromatography test showedthat the extract of A. cordifolia stem contained flavonoids, polyphenols, and saponin.
DYNAMICS THE ZONATION POLICY SYSTEM FOR UPPER SECONDARY STUDENT ADMISSIONS IN KAMPAR DISTRICT RIAU PROVINCE Nurman, Nurman; Kumalasari, Eka; Erlina, Erlina; Yuli, Annisa Rahma
CosmoGov: Jurnal Ilmu Pemerintahan Vol 10, No 1 (2024)
Publisher : Department of Government, FISIP, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cosmogov.v10i1.51151

Abstract

The development of information technology has entered various fields. Utilization of information and telecommunications technology in public services. It is no longer something new for developed countries. Apart from that, there is demand from the public for information which requires the Government to provide public services that suit the needs of the community. Policy implementation is one of the stages of public policy, between policy formation and the policy consequences for the communities it influences. If a policy is inappropriate or cannot reduce the problem that is the target of the policy, then the policy will probably fail even if the policy is implemented very well. Meanwhile, a policy that has been planned very well may also fail if the policy is not implemented well by the policy implementers. The aim of this research is to determine the Policy Dynamics of the Zoning System for Admission of High School Students in Kampar Regency, Riau Province. This research uses a qualitative method with stages including preparing a research design, determining the location and research informants, collecting data, analyzing data, presenting data and drawing conclusions. Research findings show that the school and local government cannot confirm zoning boundaries so that prospective new students cannot register and fail to enter the nearest school even though they are in the zone and end up enrolling in private schools which require a lot of education costs.gb777
ANALISIS BIAYA PASIEN COVID-19 DI RUMAH SAKIT X KOTA BANJARMASIN Aisyah, Noor Aisyah; Aisyah, Noor; Norhilaliyah, Norhilaliyah; Wahyuni, Amaliyah; Kumalasari, Eka; Yumassik, Abdul Mahmud; Illahi, Fitrah Shafran
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1936

Abstract

COVID -19 is designated as an infectious disease that causes an outbreak and causes a public health emergency. COVID-19 causes death and absorbs significant disease costs. The research aims to determine the average cost of inpatient COVID-19 patients at hospitals in the city of Banjarmasin. This research is a descriptive non-experimental study using observational research methods, data was taken retrospectively to provide an overview of the costs of COVID-19 patients. The research sample is data on costs for inpatient COVID-19 patients in March-April 2020 at Hospital x Banjarmasin City with a sample size of 347 treatment episodes. The research results show that the average cost for a COVID-19 patient per episode of treatment is IDR 13,095,609. The total cost of all episodes of care for hospitalized COVID-19 patients is IDR 4,544,176,469. The first largest cost component that absorbs the most costs is the cost of drugs and medical materials amounting to IDR 1,236,714,000 per component with an average of IDR 3,564,017 per episode of care (27.215%). The second largest cost component is room costs, namely IDR 781,624,400 with an average cost of IDR 2,252,520 per treatment episode (17.20).
PERBANDINGAN PELARUT ETANOL-AIR DALAM PROSES EKSTRAKSI DAUN BAWANG DAYAK (Eleutherine palmifolia Linn) TERHADAP AKTIVITAS ANTIOKSIDAN DENGAN METODE DPPH Kumalasari, Eka; Musiam, Siska
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i3.2290

Abstract

The immune system can be damaged by the presence of free radicals. The formation of free radicals must be prevented by antioxidants. Humanes basically do not have antioxidant reserves in their her body, so that when there is exposure to excessive the radicals then the needs body antioxidant intake from the outside. At present it is encouraged the development of antioxidants derived from plants, which are relatively easier to obtain and safe for humans consumption. Potential to antioxidant plants one of them is dayak onion leaves. Dayak onion leaves are a typical plant Borneo Central used by the Dayak tribe as medicine. To get a high active ingredient in dayak onion leaves, it is necessary to optimize the type of maceration solvent. The types of solvents used are water and ethanol. Testing of antioxidant using activities DPPH (2,2-Diphenyl-1-picrylhydrazyl) as a free radical compound. The maximum wavelength of DPPH in this study is at 519 nm. The highest IC50 value was found on dayak onion leaf extract with water solvent which was 58.62 ppm, with ethanol-water solvent of 33.71 ppm, and the smallest with ethanol solvent of 26.98 ppm. Key: antioxydan, Eleutherine palmifolia of leave, DPPH
Formulasi masker gel peel-off “ELCI” (Eleutherine palmifolia dan Citrus reticulata) sebagai antioksidan Kumalasari, Eka; Prihandiwati, Erna; Nafisa Berliana, Siti; Marta Fransiska, Revita
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/x8hk1p37

Abstract

UV radiation can cause skin damage, including premature aging. Preventing premature aging can be accomplished by the use of cosmetic goods, such as a peel-off gel mask. ELCI is a unique peel-off gel mask with Dayak leek extract (Eleutherine palmifolia) and orange peel extract (Citrus reticulata). These two active compounds have extremely high antioxidant activity. Antioxidants can help prevent aging by reducing ROS generation. The goal of the study is to find the best ELCI peel-off gel mask recipe thatmeets the standards and provides the most synergistic advantages achievable. ELCI is derived from oven-dried plants and extracted utilizing a maceration procedure with 70% ethanol as the solvent. ELCI was divided into three formulae with varying extract compositions for laboratory testing of the preparation's physical qualities. The study found that all ELCI peel-off gel mask compositions passed the physical characteristics test, which included organoleptic, homogeneity, adhesive power, spreadability, pH, dry time, and viscosity. All formulations remained stable during storage after undergoing a 6-cycle cycling test was not significantly different (p>0,05).
FORMULASI DAN EVALUASI FISIK SEDIAAN MASKER CLAY KOMBINASI EKTRAK ETANOL DAUN BAWANG DAYAK DAN KULIT JERUK SIAM Musiam, Siska; Ma'ruf, Muhammad; Kumalasari, Eka
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i3.2298

Abstract

Clay masks are a popular cosmetic due to their ability to rejuvenate the skin and detoxify the face. Clay masks can be made by adding dayak onion leaves and Siamese banjar orange peel, known to be rich in natural antioxidants containing various complex secondary metabolites. The aim of this research is to formulate and evaluate a clay mask preparation made from a combination of ethanol extracts of dayak onion leaves and Siamese banjar orange peel. The samples were extracted using the maceration method with 70% ethanol as a solvent. The ethanol extracts were then formulated into clay masks using kaolin as the base material, with ratios of 1:1, 2:1, and 1:2. The organoleptic evaluation showed no changes in color, odor, or texture of the masks during storage. All formulations were homogeneous with an average pH ranging from 5.19 to 5.97. The viscosity test results ranged from 29.14 to 37.05 Pa’s, the average spreadability was 27.12-38.90 mm, and the drying time ranged from 15.21 to 17.58 minutes. It can be concluded that the ethanol extract combination of dayak onion leaves and Siamese banjar orange peel can be formulated into a stable clay mask and all formulations meet the required physical evaluation.
THE IMPACT OF PVA CONCENTRATION ON THE PHYSICAL QUALITY OF THE Eleutherine palmifolia (L.) Merr LEAVES PEEL-OFF GEL MASK Kumalasari, Eka; Prihandiwati, Erna; Ma'ruf, Muhammad; Ariani, Novia; Amelia, Senya Puteri; Fawwazi, Muhammad Hafizh Abiyyu Fathin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 9 No 2 (2024): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v9i2.2277

Abstract

The natives of Central Kalimantan utilize Eleutherine palmifolia (l.) Merr as a traditional medicine to treat various diseases. Eleutherine palmifolia  leaves are rich in flavonoid substances. Eleutherine palmifolia  leaves extract has an IC50 value of 45.33 ppm, indicating significant antioxidant activity. Antioxidants are helpful in reducing the risk of UV radiation-induced skin damage. Eleutherine palmifolia leaves have antioxidant properties that can be used as a peel-off gel mask. Polyvinyl alcohol (PVA) bases come in various formulations for peel-off gel mask that F1 10%, F2 12%, and F3 14%. The concentration of PVA is the most significant element affecting how well peel-off gel masks create films. This study aims to determine the impact of PVA concentration on the physical of the Eleutherine palmifolia  leaves Peel-off gel mask. All formulas are tested for organoleptics, homogeneity, spreadability, pH value, and drying speed. The results showed that all peel-off gel mask compositions pass the physical properties test. A one-way ANOVA statistical analysis reveals a significant variation in the preparations drying speeds (p<0,05).
Co-Authors Achmad Mursyidi Aisyah, Noor Aisyah, Noor Aisyah Amelia, Senya Puteri Ariani, Novia Aryzki, Saftia Danang Prasetyaning Amukti Erlina Erlina Febrianti, Dwi Rizki Hamidah, Marina Illahi, Fitrah Shafran Khadijah, Maulida Laela Hayu Nurani Linda Fitria Wahyuni Ma'ruf, Muhammad Marta Fransiska, Revita Muhammad Hafizh Abiyyu Fathin Fawwazi Muhammad Ma'ruf Nafisa Berliana, Siti Nanang Fakhrudin, Nanang Nanik Sulistyani Nayandra, Faizah Niah, Rakhmadhan Norhilaliyah, Norhilaliyah Normilawati Nour Athiroh Abdoes Sjakoer Nurman Nurul Jadid Mubarokati Prihandiwati, Erna Purnomo, Dimas Kalinggo Rahayu, Mirenne Anik Sri Riski, Akhmad Riza Alfian Rohman, Abdul Sandi, Dita Ayulia Dwi Santoso, Blegoh Iwan Siska Musiam Subagus Wahyuono Supomo Supomo Wahyuni, Amaliyah Widyarini, Sitarina Yuli, Annisa Rahma Yumassik, Abdul Mahmud Zainab Zainab