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GAMBARAN TINGKAT PENGETAHUAN PENGGUNAAN OBAT TRADISIONAL HIPERTENSI PADA PENDERITA HIPERTENSI DI KABUPATEN PELALAWAN PROVINSI RIAU Husnawati, Husnawati; Sastrawati, Atriwida; Pratiwi, Erniza; Laia, Cindy Oktaviana
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.149

Abstract

Traditional medicine is an ingredient or ingredient in the form of plant material, animal material, mineral material, sarian preparation, or a mixture of these materials which have been used. One of the traditional treatments carried out by the community is for the treatment of hypertension. Knowledge is the result of knowing and occurs after someone has sensed a certain object. This study aims to describe the level of knowledge of the use of traditional hypertension drugs in patients with hypertension. The benefits of this study are to know the level of knowledge of hypertension sufferers in using traditional hypertension drugs. The design in this study was an observational study with descriptive methods. The sample was selected using purposive sampling technique. Data collection wasdone by using a questionnaire. Based on the results of the study, it was found that the description of the level of knowledge of respondents in using traditional hypertension medicine was generally categorized as good, namely as many as 77 respondents, the level of knowledge of respondents in the sufficient category as many as 20 respondents and as many as 3 respondents had a low level of knowledge.
POTENSI INTERAKSI OBAT PADA PASIEN PNEUMONIA Sinata, Novia; Pratiwi, Erniza; Rosidi, Fatmarzuqni Putri
Jurnal Farmasi Higea Vol 16, No 1 (2024)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v16i1.503

Abstract

Pneumonia merupakan suatu peradangan akut parenkim pada paru-paru yang disebabkan oleh mikroorganisme meliputi bakteri, virus, jamur dan parasit. Penggunaan beberapa obat dalam terapi pneumonia dapat meningkatkan terjadinya Drug Related Problem salah satunya potensi terjadinya interaksi obat.Tujuan penelitian ini untuk mengetahui potensi interaksi obat pneumonia di Puskesmas Rokan IV Koto Kabupaten Rokan Hulu. Data diperoleh dari rekam medik secara retrospektif dan dianalisis dengan metode observasional secara deskriptif. Sampel yang digunakan dalam penelitian ini adalah 69 data rekam medik pasien pneumonia pada tahun 2020. Penelitian potensi interaksi obat pada pasien pneumonia berdasarkan jenis interaksi obat secara farmakokinetik, farmakodinamik, dan unknown serta berdasarkan severity (tingkat keparahan) terdiri dari major, moderat dan minor. Hasil penelitian menunjukkan bahwa ditemukan adanya potensi interaksi obat pneumonia dengan obat lain sebanyak 118 kasus. Interaksi terdiri dari jenis interaksi farmakokinetik sebesar 11,86%, farmakodinamik sebesar 72,03% dan interaksi unknown sebesar 16,10%. Berdasarkan severity (tingkat keparahan) terdapat pada tingkat keparahan major sebesar 5,08%, moderat sebesar 44,92%, minor sebesar 50,00 %. Kombinasi obat yang banyak berpotensi interaksi adalah azitromisin dengan salbutamol sebesar 25,42% dengan severity (tingkat keparahan) moderat dan jenis interaksi sinergisme farmakodinamik.Kata kunci: Interaksi Obat; Pneumonia; Rekam Medik
Peningkatan Pengetahuan HIV/AIDS di Kalangan Siswa SMA melalui Penyuluhan di SMAN 19 Pekanbaru, Riau: HIV/AIDS Pratiwi, Erniza; Ikhtiarudin, Ihsan; Furi, Mustika; Sari, Seftika; Ramadhan, Fariz Putra; Hidayati, Fika; Rahmi, Helvy; Lestari, Indah; Wahyuni, Indah; Deswinda, Intan Ayu; Shelna, Khafiza; Lestari, Kurnia Dwi; Anggraini, Laurentin Leni; Zahira, Rifka
Inovasi Jurnal Pengabdian Masyarakat Vol 2 No 3 (2024): IJPM - Desember 2024
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/ijpm.596

Abstract

Human Immunodefiency Virus (HIV) merupakan kelompok retrovirus yang mempunyai kemampuan dalam menduplikasi, mencetak dan memasukkan materi genetik sehingga menyebabkan Acquired Immunodeficiency Syndrom (AIDS) yang dapat melemahkan sistem kekebalan tubuh seseorang dan merupakan penyebab infeksi ikutan (oportunistik). Remaja adalah masa seseorang atau individu berada pada mobilitas sosial yang paling tinggi dan akan membuka peluang baginya untuk terpapar pada berbagai perubahan sosial, kultural, budaya, fisik maupun psikologis sehingga remaja merupakan kelompok usia yang paling berisiko mengalami penularan HIV/AIDS. Sasaran dari kegiatan ini adalah siswa Sekolah Menengah Atas (SMA) yang berlokasi di SMAN 19 Pekanbaru. Waktu pelaksanaan pengabdian yaitu pada tanggal Rabu, 20 Maret 2024 (08.00 WIB s/d selesai). Pengabdian ini dilakukan dengan cara observasional yang bersifat deskriptif dengan metode pengambilan data secara cross sectional melalui pengisian lembar kuesioner tentang HIV/AIDS. Hasil penelitian menunjukkan berdasarkan data jenis kelamin dari total 61 responden terdapat 34 responden laki-laki dengan perolehan skor pretest sebesar 55,05% dan skor post-test sebesar 78,99%. Kemudian terdapat sebanyak 27 responden perempuan dengan perolehan skor pretest sebesar 55,68% dan skor post-test sebesar 79,99%. Berdasarkan hasil penelitian dan pengabdian masyarakat yang telah dilakukan di SMAN 19 Pekanbaru, penyuluhan HIV/AIDS dapat meningkatkan pengetahuan siswa SMAN 19 Pekanbaru dari kategori tingkat pengetahuan kurang, naik menjadi kategori tingkat pengetahuan tinggi.
EVALUASI SIFAT FISIK SUSPENSI REKONSTITUSI AMOKSISILIN GENERIK BERMEREK DI APOTEK KOTA BANGKINANG Nofriyanti; Agistia, Nesa; Pratiwi, Erniza
Jurnal Farmamedika (Pharmamedika Journal) Vol 9 No 2 (2024): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v9i2.344

Abstract

Penyakit infeksi merupakan masalah kesehatan yang penting, obat andalan untuk mengatasinya adalah antibiotik. Amoksisilin merupakan antibiotik spektrum luas yang banyak digunakan pada infeksi yang disebabkan bakteri. Amoksisilin bersifat sukar larut di dalam air, sehingga dibuat dalam bentuk suspensi rekonstitusi. Penambahan volume cairan rekonstitusi yang tidak tepat dapat mempengaruhi efektivitas kerjanya. Penelitian ini bertujuan untuk mengetahui apakah sifat fisik sediaan suspensi rekonstitusi amoksisilin yang diambil di apotek di kota Bangkinang memenuhi persyaratan sesuai dengan yang tertera di dalam Farmakope Indonesia Edisi VI dan pustaka lainnya. 30 botol suspensi amoksisillin dengan nomor batch yang sama, ditambahkan air sesuai tanda batas yang tertera pada wadah dan kemudian dievaluasi sifat fisiknya, meliputi organoleptis, pH, bobot jenis, viskositas, volume sedimentasi, waktu redispersi dan volume terpindahkan yang diuji selama 7 hari penyimpanan. Diperoleh hasil uji organoleptik, pH, bobot jenis, viskositas, volume sedimentasi dan waktu redispersi yang memenuhi persyaratan selama penyimpanan 7 hari. Akan tetapi pada pegujian volume terpindahkan tidak sesuai dengan persyaratan pada Farmakope Indonesia edisi VI.
ANALISIS RISIKO REAKSI OBAT YANG TIDAK DIKEHENDAKI PADA PASIEN HIPERTENSI GERIATRI DI RSUD ARIFIN ACHMAD PROVINSI RIAU Septi Muharni; Erniza Pratiwi; Yuwanda Iswari
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.224

Abstract

Adverse Drug Reaction (ADR) is every adverse event related to the use of a drug in humans. Geriatrics have a 7 times greater risk of developing ADR. Hypertension is the most common disease suffered by geriatric patients. The purpose of this study was to analyze the risk of ADR occurrence in geriatric hypertension patients and also to analyze the relationship of demographic data with the incidence of ADR. This study was carried out in an observational manner which was descriptive analytic with a cross sectional approach in 88 medical record samples of geriatric hypertension patients in inpatient installations using gerontoNET scores. Based on the ADR risk variable according to the gerontoNET score, there was 1 patient with ≥4 comorbid, 45 patients had heart failure, 5 patients had liver disorders, 19 patients received 6-7 drugs and 37 patients received ≥8 drugs, no patients with ADR history, and 28 patients developed kidney problems. From the results of this study, there are 37 patients who have a high risk of ADR events which are marked by gerontoNET score ≥4. Based on the correlation analysis of gender and age range on ADR risk obtained a weak relationship and no significant correlation (r = 0.116, p = 0.116; r = 0.017, p = 0.847), so that gender and age in geriatric hypertension patients are not related to the risk of ADR.
PEMBERIAN EDUKASI TENTANG CARA MENGATUR OBAT BAGI LANSIA AGAR TETAP SEHAT SELAMA RAMADHAN DI UPT PSTW HUSNUL KHOTIMAH Djohari, Meiriza; Pratiwi, Erniza; Fadhli, Haiyul; Safitri, Devi; Rifani, Mhd; Putri, Sella Hilmalia Nur Al; Sumbarita, Silvia; Rahmatunnur, Siti; Mardianti, Tengku Shella; Muti’ah, Try Hadirah; Azizah, Wahyu; Zamri, Wiedya Alfitrya; Maqfiroh, Wirdarani
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 7 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Juli 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i7.1574

Abstract

Elderly people who undergo regular drug therapy often face problems in adjusting the time they take medication during fasting. This is due to changes in eating schedules during Ramadan. Some medications may require adjustments in dose, frequency, or even formulation so that they continue to work well. The aim of this service is to increase public understanding, especially the elderly, about how to manage medication schedules and doses during fasting. Service activities are carried out using a demonstration and discussion system by giving brochures to the elderly at UPT PSTW Husnul Khotimah. Starting from filling out the questionnaire sheet (pre-test), distribution of brochures, verbal education and ending with filling out a questionnaire sheet (post-test) related to participants' understanding of the information that has been presented. Based on the results, an increase in the average value was obtained pre-test by 41.25% to 72.16% in post-test, and in statistical tests with Paired Sample Test shows a significance value of 0.000, which indicates there is a significant difference between before and after counseling. So it can be concluded that the counseling carried out at UPT PSTW Husnul Khotimah significantly increased the knowledge of the elderly, especially regarding the use of medication during fasting.
Analisis Komparatif Sosiodemografi Terhadap Kepatuhan Penggunaan Antihipertensi Pada Pasien Hipertensi RSUD Puri Husada Tembilahan Husnawati, Husnawati; Pratiwi, Erniza; Syafitri, Yellia; Laia, Cindy Oktaviana; Zulfitri, Reni
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.240

Abstract

Hypertension is a condition where systolic blood pressure increases to more than 140 mmHg and diastolic blood pressure to more than 90 mmHg. Compliance with antihypertensive medication is crucial. Hypertension cannot be cured and must be consistently monitored to prevent complications that can lead to death. One of the factors that can affect the level of medication adherence in patients is the patient's sociodemographics including age, gender, educational level and employment status. The purpose of this study was to analyze the effect of sociodemography on compliance with antihypertensive use in hypertensive patients at Puri Husada Tembilahan Hospital. This research is an observational study with a cross-sectional research design with analytic descriptive method. The sample in this study were patients with a primary diagnosis of hypertension with or without comorbidities who went to the Puri Husada Tembilahan Hospital at the time of the study and met the inclusion criteria. Based on the results of the study it was found that of the 4 sociodemographic aspects studied, namely age, gender, education level and employment status, only education level affected the level of adherence to taking medication in hypertensive patients (P value = 0.000), where respondents with higher education levels had higher levels of higher adherence than respondents with low levels of education.
Formulasi dan Uji Aktivitas Serum Spray Gel Minyak Adas (Feoniculum Vulgare Mill.) terhadap Bakteri Propionibacterium Acnes Agistia, Nesa; ., Nofriyanti; Pratiwi, Erniza; Azizah, Mifza
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2449

Abstract

Acne is a prevalent dermatological condition primarily caused by the bacterium Propionibacterium acnes. Antibiotics are used in acne therapy; however, increasing bacterial resistance has been reported in numerous studies. Fennel (Foeniculum vulgare Mill.) essential oil is known to exhibit antibacterial properties, mainly due to its active constituents, anethole and fenchone. This study aimed to develop a pharmaceutically stable serum spray gel formulation containing fennel essential oil and to evaluate its anti-acne activity. Fennel essential oil was formulated into serum spray gel preparations at concentrations of 10%, 15%, and 20%. The formulations were evaluated for organoleptic characteristics, pH, homogeneity, viscosity, flow behavior, adhesiveness, physical stability, spray pattern, and antibacterial activity.The results demonstrated that all serum spray gel formulations exhibited good physical stability, as indicated by acceptable organoleptic properties, homogeneity, pH values, viscosity, flow behavior, adhesiveness, stability, and spray patterns. One-way analysis of variance (ANOVA) revealed a statistically significant difference (p < 0.05) among the formulations in terms of antibacterial activity, as measured by the diameter of the inhibition zones. Post hoc Tukey analysis showed that the 10% fennel essential oil formulation exhibited the highest antibacterial activity, with an inhibition zone diameter of 23.6 mm, which was classified as strong antibacterial activity.
ISOLASI DAN UJI AKTIVITAS DAYA HAMBAT EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP BAKTERI PADA LIDAH Djohari, Meiriza; Putri, Wulandari Yulia; Pratiwi, Erniza
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i3.57

Abstract

Betel nut (Areca catechu L.) is a natural material that has antibacterial activity in treating diseased on teeth, halitosis and can inhibit of dental caries. The objective of this research is type of bacteria based on morphology, the results of bacterial identification tests on the tongue and to determine the effect of the inhibitory power of betel nut ethanol extract (Areca catechu L.) to bacteria of the tongue. Antibacterial activity testing using disc diffusion method with various concentrations of 10%, 20% and 30%. Secondary metabolite contents are alkaloid, terpenoid and flavonoid.The results obtained from the identification test based on the color of bacteria Branhamella catarrhalis, Staphylococcus epidermidis and Straphylococcus aureus. Ethanol extract of areca nut (Areca catechu L.) is better to inhibiting the growth of Staphylococcus epidermidis and Staphylococcus aureus compared to Branhamella catarrhalis. Based on Two Way Anova statistical data on inhibitory zone diameters, there were differences between the concentration groups of 10%, 20% and 30% and there were significant differences in the inhibitory activity of Branhamella catarrhalis bacteria compared to Staphylococcus epidermidis and Straphylococcus aureus bacteria but not significantly different between Staphylococcus epidermidis and Straphylococcus aureus bacteria
Health Related Quality of Life (HRQoL) in Type 2 Diabetes Mellitus Patients Based on Antidiabetic Prescription Patterns Seftika Sari; Erniza Pratiwi; Dinda Farahdilla; MT Ghozali; Indriyati Hadi Sulistyaningrum; Prasojo Pribadi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008444

Abstract

Diabetes mellitus is characterized as a multifaceted metabolic disorder marked by elevated blood sugar levels or hyperglycemia. Among its types, type 2 diabetes mellitus is the most common globally, significantly affecting a large portion of the population. In Indonesia, there has been a notable increase in the prevalence of type 2 diabetes, indicating a rising trend. This condition necessitates continuous care and management since it is incurable, requiring patients to undergo lifelong treatment. The various therapeutic approaches available for managing type 2 diabetes have a significant impact on the quality of life of patients, highlighting the necessity for quality-of-life assessments. The primary objective of this study was to assess the quality of life among individuals diagnosed with type 2 diabetes mellitus. It also aimed to investigate the effects of different patterns of antidiabetic drug prescriptions on the Health-Related Quality of Life (HRQoL), employing the Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) for evaluation. This study was conducted as a quantitative, observational research using a cross-sectional approach and a descriptive analytical method. A total of 99 participants were included through purposive sampling, a non-probability sampling technique. The findings showed that the average quality of life score was 70.56, with 48 participants (48.5%) reported to have a good quality of life and 51 (51.5%) considered to have a poor quality of life. Importantly, significant results (p0.05) were found regarding the positive effects of combining oral antidiabetic drugs with insulin on enhancing the quality of life in individuals with type 2 diabetes, underscoring the influence of medication regimens on patient health outcomes.