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All Journal Majalah Kedokteran Bandung Berkala Ilmu Kesehatan Kulit dan Kelamin Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Journal of General Procedural Dermatology and Venereology Indonesia Seroja Husada: Jurnal Kesehatan Masyarakat
Asri, Ennesta
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Computer Science & IT Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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A Case of Longitudinal Melanonychia in A Child: Benign or Malignant? Putri, Heffi Anindya; Asri, Ennesta; Anum, Qaira
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 6, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Longitudinal melanonychia (LM) describes a longitudinal brown-to-black band of discoloration affecting a finger, thumb, or toenail. Discoloration of the nails can be a sign of benign or malignant nail disorders. Although nail melanoma rarely occurs in children, health practitioners should be aware of melanonychia. Dermoscopy and histopathology are helpful in the diagnosis. Case Illustration: A case of LM in a thirteen-year-old girl was reported with a complaint of brownish-black discoloration, sometimes painful, on her right thumb since 1 year ago. She had no history of trauma, nail damage, or bleeding tendency. Dermatological examination found a homogeneous brownish-black band on the right thumbnail. Dermoscopy revealed regular, homogeneous black linear pigmentation and pigment through the translucent cuticle and proximal nail fold (pseudo-Hutchinson’s sign). Punch biopsy was done on proximal nail fold reaching nail matrix. Histopathology revealed increased melanocytes, some nests of melanocytes in rete Malpighi, and no atypical cells. She was diagnosed with nail matrix nevus. Five months after the punch biopsy, the nail grew well without onychodystrophy. Discussion: Nail matrix nevus is a benign LM. Diagnosis is based on anamnesis, physical examination, dermoscopy, and histopathology. Dermoscopy of the nails is a useful, quick, non-invasive, and highly effective tool that may help differentiate benign or malign melanonychia. Conclusion: Histopathology is important to determine whether the pigmented lesion is benign or malignant.
Profil Pasien Lupus Eritematosus Kutaneus di Rumah Sakit Umum Pusat Dr M Djamil Padang Periode 2015 - 2020 Tiffany, Begum; Akhyar, Gardenia; Revilla, Gusti; Asri, Ennesta; Tofrizal, Tofrizal; Afriani, Nita
Seroja Husada: Jurnal Kesehatan Masyarakat Vol. 1 No. 6 (2024): Seroja Husada: Jurnal Kesehatan Masyarakat
Publisher : Seroja Husada: Jurnal Kesehatan Masyarakat

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Lupus eritematosus kutaneus (LEK) merupakan salah satu dari jenis penyakit lupus eritematosus (LE) yang merupakan penyakit autoimun dengan variasi klinis luas. Walaupun penyebab lupus jenis manapun belum jelas diketahui, salah satu faktor pencetus yang mungkin jadi penyebab penyakit ini adalah faktor hormon, paparan sinar matahari, dan faktor lainnya. Sama seperti lupus eritematosus lainnya, LEK lebih sering terjadi pada wanita usia subur dibandingkan dengan laki laki dengan manifestasi klinis yang muncul di kulit yang dapat dipicu karena paparan sinar matahari. Hal ini ditambah dengan manifestasi klinis lain selain manifestasi pada kulit yang juga muncul, dapat menimbulkan masalah yang mempengaruhi kualitas hidup penderitanya.Tujuan dari penelitian ini adalah untuk mengetahui profil klinis pasien LEK di RSUP Dr M Djamil Padang periode 2015-2020. Populasi dalam penelitian ini adalah seluruh pasien LEK di RSUP Dr M Djamil Padang periode 2015-2020, dengan total 20 data. Data sekunder berupa rekam medis pasien LEK digunakan dalam penelitian ini, dan disajikan dalam bentuk narasi dan tabel distribusi frekuensi.Hasil penelitian ini diperoleh jumlah penderita LEK di Rumah Sakit Umum Pusat Dr M Djamil Padang tahun 2015 - 2020 adalah sebanyak 17 orang penderita LES dan LEK, dan 3 orang penderita LEK saja dari 354 orang penderita LE. Jumlah pasien LEK perempuan jauh lebih banyak dari pasien laki laki. Distribusi kelompok umur terbanyak adalah berusia 15-24 tahun.
Non-Metallic and Metallic Toxicant Exposures from Personal Care Products in Indonesian Male and Female Medical Students Putra, Alby Dwinanda; Syamsir, Elmatris; Yulistini, Yulistini; Khaira, Fathiyyatul; Asri, Ennesta; Ilmiawati, Cimi
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3254

Abstract

Students can gain various benefits from their daily personal care products. However, the chemicals contained in these products may have adverse health effects. Regardless the inspection performed by regulatory agencies on these products, the products circulating in the market may still contain toxicants thus may jeopardize their safety for use. This study evaluated toxicant ingredients contained in personal care products used by male and female college students. This study was conducted from September to December 2022 on 23 male and 46 female college students of the Faculty of Medicine, Universitas Andalas, Indonesia. Data were collected using a 69-items validated questionnaire. Results were then presented as a distribution of products used categorized by body areas and potentially toxic metallic and non-metallic ingredients identified from their labels. Female college students used at least 10 personal care products, with a median of 19 products. Male students used at least four products and a median of eight products. Investigation on the label of skin, hair, eye, dental and oral, lips, and nail personal care products demonstrated the presence of metallic and non-metallic toxicants. Five metallic toxicants (aluminum, titanium, zinc, copper, and chromium) and 15 non-metallic toxicants (triclosan, talc, fragrance, parabens, butylated hydroxyanisole, butylated hydroxytoluene, diethanolamine, triethanolamine, butylene glycol, propylene glycol, polyethylene glycol, phthalates, benzophenone-3, acetone, and fluoride) were identified. Thus, numerous toxicants are present in marketed personal care products, and females are exposed more than males to these toxicants. Consumers need to be more critical in their choice of personal care products.
The Effect of Alpha Mangostin on The Expression of TGF-β1, SMAD3, Type I Collagen, Proliferation and Migration of Keloid Fibroblasts Asri, Ennesta; Rina Gustia; Indah Indria Sari; Jefrizal Wirman; Yufaz Aidi Mahesa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 1 (2025): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V37.1.2025.41-47

Abstract

Background: Keloid is a process of abnormal collagen thickening during wound healing in skin tissue accompanied by the formation of new blood vessels. Many keloid therapy modalities have been developed but the recurrence rate of those treatment still ranged 1-70%. Herbal plants have been developed for various types of treatment, one of which is for treating keloids. Purpose: The alpha mangostin content in mangosteen peel is known to have antifibrotic properties, further research is needed regarding the administration of alpha mangostin on the process of keloid occurrence. Methods: The investigation was conducted in vitro on phase III keloid fibroblast cells. There were two groups, which divided into the control groups and the treatment groups. The control groups and treatment groups were given alpha mangostin extract in concentrations of 20 μM; the sample of this study was 16. For each group after 24h of the incubation, fibroblast cell proliferation was measured by Microtetrazolium (MTT) assay, fibroblast cell migration was measured by scratch assay, SMAD3 expression was measured after immunocytochemical staining, and type 1 collagen was measured by Enzyme-Linked Immunosorbent Assay (ELISA). The Ethics Committee at the Research Ethics Commission of Faculty of Medicine Andalas University has reviewed this research. Result: Alpha mangostin can reduce the average expression of TGF-β1, SMAD3 expression, type 1 collagen, proliferation, and migration.  . Conclusion: At concentration of 20 μM, alpha mangostin suppressed TGF-β1 expression, SMAD 3, collagen type 1, proliferation, and migration in keloid fibroblast cell.
Community Empowerment of Nagari Salimpek in Developing a Herbal Cosmetic Village Based on Family Medicinal Plants (TOGA) Yenny, Satya Wydya; Gustia, Rina; Rahmatini; Usman, Elly; Asri, Ennesta; Akhyar, Gardenia; Ariani, Tutty; Sari, Mutia; Sari, Indah Indria; Yossy, Vesri; Julia, Dwi Sabtika; Ashar, Miranda; Taria, Sari Almira
Warta Pengabdian Andalas Vol 33 No 1 (2026)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.33.1.67-74.2026

Abstract

Nagari Salimpek in Alahan Panjang, West Sumatra, has a potential for wellness tourism due to its rich biodiversity, especially medicinal and cosmetic plants. However, community awareness in managing Family Medicinal Gardens (TOGA) remain limited, with only three of twenty household groups actively cultivating herbal plants. This condition emphasizes the need for community empowerment to optimize health and economic benefits from local resources. This community service program aimed to enhance local capacity in cultivating and processing TOGA as the basis for developing a Herbal Cosmetic Village. The programme began on 19 July 2025 and was evaluated over six months. Activities included educational sessions on TOGA utilization, training on herbal and cosmetic plant processing, distribution and planting of herbal seeds, and the signing of a Memorandum of Agreement (MoA) with local stakeholders. A pre-test and post-test evaluation involving 31 participants showed significant improvement in knowledge, with understanding of the “herbal center village” concept rising from 29% to 55% and awareness of Nagari Salimpek’s potential increasing from 32% to 77%. Overall, participants gained broader insights into the role of TOGA in health, cosmetics, and economic development. These results highlight the importance of continued education, mentorship, and government support to establish Nagari Salimpek as a model Herbal Cosmetic Village for wellness tourism.
Co-Authors Adiba, Yasmine Shofi Aningdia Afriani, Nita Anum, Qaira Ariani, Tutty Ashar, Miranda Asterina, Asterina Cimi Ilmiawati, Cimi Dwi Sabtika Julia Fathiyyatul Khaira, Fathiyyatul Gardenia Akhyar Gusti Revilla Indah Indria Sari Jefrizal Wirman Putra, Alby Dwinanda Putri, Heffi Anindya Rahmatini . Rina Gustia Sari, Indah Indria sari, Mutia Satya Wydya Yenny Syamsir, Elmatris Taria, Sari Almira Tiffany, Begum Tofrizal Yossy, Vesri Yufaz Aidi Mahesa Yulistini, Yulistini