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All Journal Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Chemistry Proceeding ISETH (International Summit on Science, Technology, and Humanity)
lubis, muhammad fauzan
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Social Sciences Other

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New Insights of Response Surface Methodology Approach in Optimizing Total Phenolic Content of Zanthoxylum acanthopodium DC. Fruit Extracted Using Microwave-Assisted Extraction and the Impact to Antioxidant Activity Sumaiyah, Sumaiyah; Murwanti, Retno; Illian, Didi Nurhadi; Lubis, Muhammad Fauzan; Tampubolon, Keshia
Indonesian Journal of Chemistry Vol 24, No 6 (2024)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.95922

Abstract

Zanthoxylum acanthopodium DC., a unique spice plant from North Sumatra, is rich in beneficial secondary metabolites, particularly phenolic compounds. This study utilized the microwave-assisted extraction method to enhance the extraction of these bioactive compounds. The goal was to determine the optimal extraction conditions, including solvent concentration (X1), microwave power (X2), and extraction time (X3) to maximize the total phenolic content (TPC) of Z. acanthopodium fruit. A Box-Behnken design, part of response surface methodology, was used with three factors at three levels: X1 (50%, 75%, and 100% ethanol in water), X2 (180, 300, and 450 W), and X3 (3, 8.5, and 14 min). The phenolic compounds in the optimized extract were identified using LC-HRMS, and its antioxidant activity was measured using radical scavenging activity assays. The statistical analysis indicated a significant quadratic model (p-value < 0.05), with a high R2 of 86.25%. Optimal conditions for maximum TPC (159.637 ± 5.72 mg GAE/g) were achieved with 50% ethanol, 450 W, and 8.5 min, outperforming conventional extraction methods. Compared to the non-optimized extract, the optimized extract also exhibited strong antioxidant activity, particularly in DPPH radical inhibition. This method successfully optimized TPC in Z. acanthopodium fruit, enhancing its antioxidant properties.
Training and Hedonic Survey Test of Lemon Candy Using Natural Sweetener from Sugarcane Water as an Odors Fadhillah, Nurul; Surbakti, Chemayanti; Lubis, Muhammad Fauzan; Juwita, Nur Aira
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i2.10841

Abstract

Lemon candy is a candy that has a combination of sweet and sour taste. In making lemon candy using several ingredients. One of them is using natural ingredients. Plants that can be used as ingredients for making candy are lemon juice and sugarcane juice. This community service activity involved class XI HKBP Sidorame Private High School students which was based on product innovation in the form of lemon candy with a combination of the two natural ingredients above. The purpose of this activity is to determine the level of preference (hedonic) for a product in the form of lemon candy with a combination of lemon juice and sugarcane juice. The activity begins with making a product in the form of lemon candy from a combination of lemon juice and sugarcane juice. The activity continued with data collection using pre-test, post-test and hedonic test questionnaires. The results of filling out the pre-test showed that SMAS HKBP Sidorame students' knowledge regarding lemon candy was still lacking with the percentage of yes answers to each question namely 100%, 33.33%, 20%, 6.67%, 40%. The results of filling out the post-test showed that SMAS HKBP students' knowledge was very good with the percentage of yes answers to each question namely 100%, 77%, 97%, 93%, 93%. This shows the development and increase in knowledge of SMAS HKBP Sidorame students about lemon candy. The results of the hedonic test survey obtained the highest percentage for shape parameters of 33.33% (very like), color of 43.3% (quite like), aroma of 40% (like very much), hardness of 30% (very like) and taste of 46.67% (very like). These results indicate that SMAS HKBP Sidorame students like the preparation of lemon candy.
Training and Hedonic Survey Tests of Herbal Bath Salt Products with a Combination of Jeringau and Lemon Peel as a Body Relaxant Utami, Nurhafizah; Surbakti, Chemayanti; Lubis, Muhammad Fauzan; Juwita, Nur Aira
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i2.10899

Abstract

Bath salt or better known as bath salt is a product that has recently been growing rapidly. Herbal bath salt itself is still not widely developed by the community. Herbal bath salts can be made from ginger powder and lemon peel which has a distinctive fragrance that can be relaxing for anyone who uses it. This community service activity involved class XI HKBP Sidorame Private High School students based on an innovative herbal bath salt preparation with a combination of ginger and lemon peel. The purpose of this activity is to determine the level of preference (hedonic) for a combination of lemon peel and ginger bath salt preparations. The activity began with the preparation of a combination of lemon peel and ginger bath salt. The activity ended with data collection using pre-test, post-test and hedonic test questionnaires. The results of filling out the pre-test showed that SMAS HKBP Sidorame students' knowledge was still lacking with the proportions for each question namely 23,33%, 6,66%, 10%, 0% and 30%. The results of filling out the post-test showed that the students' knowledge of SMAS HKBP was very good with a proportion of 100% for each question. This shows the development and increase in knowledge of SMAS HKBP Sidorame students about bath salts. The results of the hedonic test survey obtained the largest proportion for shape parameters of 56,66% (very like), color of 50% (like very much), fragrance of 70% (very like), hardness of 46,66% (very like) and ease of use of 63,33% (very like). These results indicate that SMAS HKBP Sidorame students like bath salt product.
The Immunomodulatory Activities of Saurauia vulcani Korth Leaves towards RAW 264.7 cell Rosidah, R; Yuandani, Y; Widjaja, Sri Suryani; Lubis, Muhammad Fauzan; Satria, Denny
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2019: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.1430

Abstract

Saurauia vulcani Korth is an actinidiaceae family plant that is used as traditional medicine by the community. Testing the immunomodulatory effect of Saurauia vulcani Korth extract was done in vitro on RAW cells line by stratified extraction using n-hexane, ethyl asetat, and ethanol solvents. Determination of nitric oxide levels by the griess method and inhibition of gene expression TNF-α, IL6, COX-2, IL-1β, and iNOS by RT-PCR method. Saurauia vulcani Korth extract (NESVL, EAESVL, and EESVL) at a concentration of 25 ug / ml was able to reduce the value of nitric oxide in RAW cells 246.7 and was able to inhibit the expression of genes TNF-α, IL-6, COX-2, IL-1β, and iNOS. Where the density value of each band formed by 1.21 ± 0.005; 1.15 ± 0.005; 0.88 ± 0.003 on TNF-α, 1.23 ± 0.003; 1.64 ± 0.005; 0.55 ± 0.003 on IL-6, 0.38 ± 0.003; 0.55 ± 0.003; 0.38 ± 0.003 on COX-2, 0.18 ± 0.003; 0.04 ± 0.003; 0.03 ± 0.003 on IL-1β, and 0.30 ± 0.003; 0.41 ± 0.003; 0.11 ± 0.005 on iNOS.
Co-Authors Denny Satria, Denny Fadhillah, Nurul Illian, Didi Nurhadi Juwita, Nur Aira Retno Murwanti Rosidah, R Sumaiyah, Sumaiyah Surbakti, Chemayanti Tampubolon, Keshia Utami, Nurhafizah Widjaja, Sri Suryani Yuandani, Y