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All Journal Anakes: Jurnal Ilmiah Analis Kesehatan
Nurdiani, Catu Umirestu
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Gambaran Hasil Procalcitonin dan D-Dimer Pada Pasien Covid-19 Di RSUD Budhi Asih Jakarta Timur Permata, Kamilia Gulin; Nurdiani, Catu Umirestu; Nugroho, Heru Purwanto; Susanti, Ellis
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 10 No. 1 (2024): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v10i1.2088

Abstract

The World Health Organization (WHO) declared an epidemic caused by Coronavirus Disease – 19 (Covid-19) on January 9, 2020. The first case was found on December 30, 2019 in Wuhan, China. The virus spreads through droplets. Symptoms of COVID-19 start from shortness of breath, cough and fever. Patients who are confirmed with COVID-19 are then carried out laboratory tests in the form of Procalcitonin (PCT) and D-dimer. This study was conducted using a descriptive method whose data was taken from laboratory examination results for the period April 2022 - May 2023 as many as 54 PCT and D-dimer result data. The results of the frequency distribution examination were based on normal values, normal PCT levels as many as 24 patients (44%) and abnormal PCT levels as many as 30 patients (56%) and normal D-dimer levels as many as 23 patients (43%) and abnormal D-dimer levels as many as 31 patients (57%). The frequency distribution in COVID-19 patients based on gender, male as many as 28 patients (52%) while in women as many as 26 patients (48%).In this conclusion, the frequency distribution of PCT and D-dimer examinations based on gender, men are higher than women. PCT examination is more with abnormal values compared to normal values. D-dimer test results with abnormal values more than normal values. Keyword            : Covid-19, D-dimer, PCT
Gambaran Kadar Elektrolit Darah (Natrium, Kalium, Klorida) Pada Pasien Balita Usia 0-5 Tahun dengan Diare Akut Di RSAB Harapan Kita Jakarta Nurdiani, Catu Umirestu; Sari, Indah Novitha Fitria; Nugroho, Heru Purwanto
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 10 No. 2 (2024): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v10i2.2368

Abstract

Diarrhea is an increase in the frequency of defecation, which is characterized by a stool consistency that is thinner than usual. Viruses, bacteria, and parasites can cause diarrhea. Diarrhea is the second most common cause of death in toddlers. The main cause of death in toddler diarrhea is severe dehydration due to excessive fluid loss. Laboratory tests on diarrhea patients include blood electrolyte tests including sodium, potassium, and chloride. This quantitative research is conducted with secondary data obtained from medical records and then processed. The study was conducted on all 64 patients aged 0-5 years with acute diarrhea at RSAB Harapan Kita. The results showed that based on gender, it was dominated by males with the highest abnormal electrolyte levels in chloride at 34 people (53.13%) with the lowest chloride value of 81 mmol/L and the highest chloride value of 125 mmol/L. Based on age, most diarrhea patients were found to occur in toddlers (1-5 years) with the highest abnormal electrolyte levels in chloride at 29 people (45.31%) with the lowest chloride value of 81 mmol/L and the highest chloride value of 114 mmol. /L. The research that has been carried out can conclude that in patients suffering from diarrhea, the average value of the patient's sodium and potassium levels is normal, while the chloride levels are high. It is hoped that it is important for parents of diarrhea sufferers to always maintain a clean environment to prevent diarrhea and immediately go to the nearest doctor or hospital when the body shows symptoms such as fever and continuous defecation.   Keywords: Diarrhea, Sodium, Potassium, Chloride
Daya Hambat Ekstrak Bunga Kenanga (Cananga odorata) dan Rosella (Hibiscus sabdariffa L.) terhadap Staphylococcus aureus ATCC BAA - 1026, Pseudomonas aeruginosa ATCC 27853 dan Proteus mirabilis ATCC 2593 Zuraida, Zuraida; Nurdiani, Catu Umirestu; Rahayu, Cahyawati; Permana, Atna; Hariutami, Desi
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 11 No. 2 (2025): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v11i2.2960

Abstract

Nosocomial infections or healthcare-associated infections (HAIs) are global health problems caused by pathogenic microorganisms, particularly antibiotic-resistant bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, and Proteus mirabilis. The increasing incidence of antibiotic resistance highlights the need to explore alternative antibacterial agents derived from natural products. This study aimed to evaluate the antibacterial activity of kenanga (Cananga odorata) and rosella (Hibiscus sabdariffa L.) flower extracts against Staphylococcus aureus ATCC BAA-1026, Pseudomonas aeruginosa ATCC 27853, and Proteus mirabilis ATCC 2593. The antibacterial activity was assessed in vitro using the disc diffusion method with various extract concentrations. The inhibitory activity of kenanga flower extract at a concentration of 100% showed average inhibition zone diameters of 27.50 mm against Staphylococcus aureus, 26.20 mm against Pseudomonas aeruginosa, and 24.20 mm against Proteus mirabilis. Meanwhile, rosella flower extract at a concentration of 100% produced average inhibition zone diameters of 33.10 mm against Staphylococcus aureus, 28.00 mm against Pseudomonas aeruginosa, and 25.20 mm against Proteus mirabilis. The results indicate that both kenanga and rosella flower extracts exhibit antibacterial activity against all tested bacteria, with inhibitory strength varying according to extract concentration. Rosella extract demonstrated higher inhibitory activity against Staphylococcus aureus, whereas kenanga extract showed significant antibacterial activity against specific test bacteria. In conclusion, kenanga and rosella flower extracts have potential as natural antibacterial alternatives to help control bacterial infections associated with nosocomial infections.   Keywords:  Antibacterial, Cananga odorata, Hibiscus sabdariffa L., Nosocomial infection, Antibiotic                                     resistance
Gambaran Kadar Elektrolit Darah Pada Pasien Diare Akut di Rumah Sakit Tk. II M. Ridwan Meuraksa Jakarta Kamaliyah, Saffanah Hayya; Rahayu, Cahyawati; Nurdiani, Catu Umirestu; Kristianingsih, Yuli; Nugroho, Heru Purwanto
Anakes : Jurnal Ilmiah Analis Kesehatan Vol. 11 No. 2 (2025): ANAKES: Jurnal Ilmiah Analis Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/anakes.v11i2.3164

Abstract

Diarrhea is a major health problem in Indonesia with the risk of dehydration and electrolyte imbalance. Electrolytes play an important role in maintaining the balance of fluids, acids-bases, as well as nerve and muscle function. This study aims to determine the overview of serum electrolyte levels (Na⁺, K⁺, Cl⁻) in patients with acute diarrhea in kindergarten hospitals. II M. Ridwan Meuraksa. This descriptive study used secondary data from the medical records of 157 patients with acute diarrhea. The laboratory examination uses the Ion Selective Electrode (ISE) method. The results showed that hyponatremia occurred in 40.6% of adult patients and 37.7% of elderly patients. Hypokalemia was found in 39.5% of adult patients and 31.1% of elderly patients. Chloride disorders were also significant, with 32.2% hypochloremia and 25% hyperchloremia in adults, and 37.7% hypochloremia and 34.4% hyperchloremia in the elderly. In conclusion, most patients with acute diarrhea experience electrolyte imbalances, especially hyponatremia and hypochloremia. Regular electrolyte checks are necessary in the treatment of diarrhea to prevent complications such as cardiac arrhythmias and kidney dysfunction. Keywords: Acute Diarrhea, Blood Electrolytes, Sodium, Potassium, Chloride.
Co-Authors Ardiansyah, Renaldi Ellis Susanti Hariutami, Desi Kamaliyah, Saffanah Hayya Kristianingsih, Yuli Latifah, Imas Masdianto, Masdianto Mukti, Septiana Widya Nugroho, Heru Purwanto Permana, Atna Permata, Kamilia Gulin Prima Nanda Fauziah Rahayu, Cahyawati Sari, Indah Novitha Fitria Sediarso Sediarso, Sediarso Sugiantari, Nining Tri Mulia Herawati Widhyasih, Retno Martini Zahrawani, Aqilah Qisthi Zuraida Zuraida