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Journal : World Nutrition Journal

Perspective of Soy Formula and Fiber intake among Non-Cow’s Milk Drinker Pediatric Patients; A Survey among Indonesian Health Care Practitioners Basrowi, Ray Wagiu; Wasito, Erika; Sundjaya, Tonny
World Nutrition Journal Vol. 4 No. S1 (2020): Special Issue : Soy Plant-based and Fiber in Children’s Gut Health, Growth & D
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V04.S1.0002

Abstract

Indonesia is one of the highest countries for soy-based product consumption, which the usage also started from early age as breastmilk substitute product, although local regulation and guideline stated that soy-based formula recommended for cow’s milk protein allergy. However, evidences showed that soy-based formula supplemented with fiber in non-cow’s milk drinker could also have health effect to gastrointestinal system. This online survey aimed to explore the perspective of health care practitioners (HCPs) in recommending soy-based formula for non-cow’s milk drinker pediatric patients, as well as identify the required additional ingredient or supplementation, specifically on fiber, in soy-based formula. Majority of respondents (97% of paediatricians (P < 0.001)), (96% of nurses  (P = 0.003)), (99% of midwives (P < 0.001)) recommended soy-based formula as nutritional product toward non-cow’s milk drinker patients. On the added ingredients required, 43% of respondents mentioned that AA and DHA and 31% mentioned that fibre is the ingredient that need to be added to complete the benefits of soy formula. This study concluded that the overall perspective of HCPs showed that soy-based formula is a nutritional product recommended for non-cow’s milk pediatric patients. However, fiber is required to be added to achieve the potential benefits of soy-based formula.
The role of prebiotics and nutrition in early stages for brain and socio-emotional development : A literature review Ramayulis, Rita; Wasito, Erika
World Nutrition Journal Vol. 5 No. S2 (2022): Special Issue : critical aspects of early life nutrition, gut health, and deve
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V05.S2.0004

Abstract

Introduction. The first 1000 days of life is the most crucial period for physical and neuro-emotional development. Since prenatal, the organ development had started and affected by many factors. Healthy neurodevelopment is dependent on socioeconomic, interpersonal and/or family, and nutritional factors. Macro- and micro-nutrients deficiencies may disrupt neurodevelopmental process. Iron, zinc, and iodium has been proven to affect brain development intrauterine and continues after birth. Prebiotics also play a role in neurodevelopmental through brain-gut-axis, but also beneficial on overall health. Methods. Advanced search for relevant literatures in PubMed, Cochrane, and Willey was conducted. After assessing the relevancy and eligibility, articles were selected and critically appraised. Conclusions. Prebiotics supplementation is beneficial in promoting gut health, thus also play a role in immune pathway and influence brain function. Many studies also shown that prebiotics might be used as additional therapy in diseases that related to gut health i.e functional gastrointestinal disorders, obesity, and allergy.
Experts’ Opinion on Immunity and Nutrition to Support Key Cognitive Functions Sekartini, Rini; Surapsari, Juwalita; Oktarina, Molly Dumakuri; Wiguna, Tjhin; Pasiak, Taufiq Fredrik; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie; Wasito, Erika
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0001

Abstract

The interaction of micronutrients and macronutrients has been shown to have a significant impact on children's cognitive development. Furthermore, proper nutrition helps a child's immune system avoid infection and disease, which can impair nutrient absorption and lead to deficiency. Microbiotas in the gut play critical roles in body physiology, including nutrient absorption, infection resistance and immune system development. Furthermore, it is known that the gut microbiota influences immune cell maturation. Finally, these three factors are thought to influence neurogenesis and cognitive development. A virtual meeting was held with five invited experts to gain a better understanding of the relationship between nutritional factors, the immune system and cognitive development.
Evidence on the importance of gut microbiota for the immune system Surapsari, Juwalita; Oktarina, Molly Dumakuri; Sundjaya, Tonny; Wasito, Erika
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0002

Abstract

Vital to the health of the host is maintaining a delicate balance in the immune system by eliminating harmful pathogens while preserving self-tolerance to prevent autoimmunity. By regulating immune homeostasis, the gut microbiota in the gastrointestinal tract provides vital health benefits to its host. It has been demonstrated conclusively that dysbiosis of these gut microbial communities can cause immune dysregulation and autoimmunity. We attempt to examine the relationship between the gut microbiota and the regulation of the innate and adaptive immune homeostasis, which can influence the development of certain disease. This literature review of recently published research and newly discovered scientific information is intended to increase awareness of the importance of maintaining a microbiota balance in the gut for immune health of the host.
Immunity as key factors that influence cognitive development on children Oktarina, Molly Dumakuri; Sekartini, Rini; Wasito, Erika; Kartjito, Melissa Stephanie
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0003

Abstract

Immune cells in the central nervous system (CNS) of the fetus are essential for normal neurodevelopment. Innate immunity-related molecules, including cytokines, toll-like receptors and complement family, are known to be expressed in the brain. Microglia, macrophage-like immune cells that reside in the brain and spinal cord, constitute 80% of all immune cells in the brain, making them the most abundant immune cell type. Acquired immunity-related molecules, such as major histocompatibility complex and antibody receptor, are also known to be expressed in the brain. In addition to this, research has demonstrated that they play important functions in the development of the brain. Neurodevelopmental diseases, including schizophrenia, autism spectrum disorders, autism-like obsessive-compulsive behaviours and social impairment, are characterized by a disruption of a wide variety of processes in the developing brain that depend on the normal function of microglia. Enteric infections and malnutrition in the first two years of life are linked to later cognitive impairment. Multiple studies have shown that bacterial and viral illnesses have direct or indirect impacts on cognitive performance in children. The immune system is in constant communication with the central nervous system and participates in the control of behaviour and a range of other essential neurological activities throughout the lifespan.
The narrative review of recent studies in understanding the relationship between gut (microbiota)-brain axis, nutrition and cognitive function Pasiak, Taufiq Fredrik; Wiguna, Tjhin; Sekartini, Rini; Surapsari, Juwalita; Sundjaya, Tonny; Wasito, Erika; Basrowi, Ray Wagiu; Kartjito, Melissa Stephanie
World Nutrition Journal Vol. 6 No. S2 (2023): Special Issue : expert perspectives on the interconnections between immunity,
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V06.S2.0004

Abstract

The concept of the gut (microbiota)-brain axis, which influences the development and function of the gastrointestinal, immune, neuroendocrine, and metabolic systems, is gaining popularity. Recent animal studies have demonstrated that the gut (microbiota)-brain axis also plays a role in establishing cognitive function. It is known that a disruption in the environment's microbiota balance can increase disease susceptibility in children. Historically, it has been hypothesized that neurodevelopmental disorders are the results of a disruption in children’s health. However, it is becoming clear that the gut microbiota and the central nervous system communicate in both directions, which could explain how microbiota affects cognitive function. Dietary factors also play important role in the central nervous system via the gut (microbiota)-brain axis, demonstrating the importance of nutrition in optimizing cognitive function. This narrative review of recently published studies and current knowledge aims to elucidate the relationship between the gut (microbiota)-brain axis and cognitive function, as well as the variables that may influence it.