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All Journal Majalah Obstetri dan Ginekologi Majalah Kesehatan FKUB Molecular and Cellular Biomedical Sciences (MCBS) Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Klinik dan Riset Kesehatan Kreasi: Jurnal Inovasi dan Pengabdian Kepada Masyaraka Jurnal Info Kesehatan
Dewi, Rose Khasana
Department Of Anatomical Pathology, Brawijaya University, Malang, East Java, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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The Effect of Flavonoids of Phaleria macrocarpa Fruit Extract on Aortic Diameter Mice Menopause Model Khoirinda, Ani; Fadilah, R. A. Rahmawati Nurul; Sutrisno, Sutrisno; Irwanto, Yahya; Dewi, R. A. Rose Khasana
JURNAL INFO KESEHATAN Vol 22 No 2 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss2.1554

Abstract

Menopause is a phase experienced by women with an age range of 45-55 years. Menopause is a condition where menstruation stops for a minimum of 12 consecutive months due to the decline in ovarian function, leading to a reduction in estrogen levels. A decrease in estrogen can lead to impaired fat metabolism resulting in atherosclerosis. This study aimed to illustrate the influence of flavonoid extract derived from Phaleria Macrocarpa on the enlargement of the aorta's diameter of mice with a menopause condition. The method of this study is a genuine experimental laboratory setting with a research design of a Randomized Post Test Only Control Group setting. Using 32 female mice divided into 6 groups: K- (without ovariectomy and flavonoid extract Phaleria Macrocarpa), K + (ovariectomy without treatment), P1 (ovariectomy + dose 3.75 mg/mice/day), P2 (ovariectomy + dose 7.5 mg/mice/day), P3 (ovariectomy + dose 11.25 mg/mice/day), and P4 (ovariectomy + dose 15 mg/mice/day). Administration of flavonoid extract Phaleria Macrocarpa was carried out for 14 days. Data analysis using statistical analysis. The results showed that in a post-hoc test, namely the administration of Phaleria macrocarpa flavonoid extract at a dose of 11.25 mg/mice/day and 15 mg/mice/day showed that it could increase the dilation of the aortic diameter of mice model menopause. The study concludes that the flavonoid fruit extract from Phaleria Macrocarpa has the ability to increase the width of the aorta in mice with a menopause condition. In future studies, it is recommended to investigate various variables in order to identify the factors that contribute to the narrowing of the aorta. Additionally, it is suggested to perform further research specifically focusing on women going through menopause.
Pelatihan Relawan Ambulan Desa dalam Menghadapi Gawat Darurat Sehari-hari dan Bencana Nagara, Aurick Yudha; Dewi, Rose Khasana; Meisani, Diah Royani; Mann, Rajveer Singh; Harjayanti, Nofita Dwi; Dhuha, Nur Syamsu; Rangkuty, Muhammad Rayyan Doli; Sallvia, Jessica Anna
Kreasi: Jurnal Inovasi dan Pengabdian kepada Masyarakat Vol. 6 No. 1 (2026): April
Publisher : BALE LITERASI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58218/kreasi.v6i1.2474

Abstract

Pre-hospital emergency care is a critical component of the Emergency Medical Services (SPGDT) to mitigate mortality and disability rates. However, village ambulance volunteers, acting as Community First Responders (CFR), frequently encounter a discrepancy between their significant responsibilities and limited clinical competencies, compounded by logistical deficits. This community service initiative aims to enhance the basic medical competence of village ambulance volunteers through structured training interventions. The implementation utilized a collaborative approach with an emphasis on hands-on practice and real-world scenarios. Data were qualitatively analyzed using Reflexive Thematic Analysis based on observations and focused discussions. The analysis identified three primary themes: (1) clinical skill deficits posing risks of evacuation malpractice (improper lifting), (2) logistical gaps in standard ambulance equipment, and (3) the efficacy of practice-based and simulation training methods. The training significantly improved participants' knowledge, technical skills (CPR, spinal stabilization, triage), and self-confidence. These findings underscore the necessity of standardizing ambulance logistics through village budgets and developing a Training of Trainers (ToT) model to ensure the sustainability of community-based health resilience.
Co-Authors Agustin Iskandar Aina Angelina Ani Khoirinda Arianto, Onni Dwi Aurick Yudha Nagara Berlian Anggraeni Putri Dhani, Fauzan Kurniawan Dhuha, Nur Syamsu Diah Prabawati Edy Mustofa Ekaputra, Aditya Airlangga Ery Olivianto Eviana Norahmawati Fabrianta, Dio Mafazi Fadilah, R. A. Rahmawati Nurul Hardika, Arif Satria Harjayanti, Nofita Dwi Harun Al Rasyid Hendy Setyo Yudhanto Hery Susilo Holipah Holipah Ihda Dian Kusuma Kenty Wantri Anita Kenty Wantri Anita, Kenty Wantri Khoirinda, Ani Kurnia Penta Seputra Mann, Rajveer Singh Meisani, Diah Royani Nurseta , Tatit Putri, Anggie Sasmita Kharisma R. A. Rahmawati Nurul Fadilah Rambe, Annisa Fadhila Aurelia Rangkuty, Muhammad Rayyan Doli Retnani, Diah Prabawati Rofifa, Amira Fithri Sallvia, Jessica Anna Sutrisno Sutrisno Sutrisno, Sutrisno Taufiq Nur Budaya Teguh Prihantoro Widodo, Robby Rinaldi Yahya Irwanto Yahya Irwanto