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Pengembangan Logistic Center Di Indonesia Sitorus, Panal
Warta Penelitian Perhubungan Vol. 22 No. 6 (2010): Warta Penelitian Perhubungan
Publisher : Sekretariat Badan Penelitian dan Pengembangan Perhubungan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25104/warlit.v22i6.1098

Abstract

Same problems of mrgo nwuement in Indonesin, among others not yet just in time sennces, not doorto door deliven;, the process of loading and unlonding at the port 5.5 clm;s, congestion, warehousingis Jar and spread mum; from the locntion of ports, industries and is still managed in conventional.Indonesw is in a position not competiti11e in tenns of Li:Jgistic Performance Index, which in 2007occupied the position 43 (score 3.01) from 150 countries. Research metlwds to obtain an opinion orperception of respondents with sampling techniques are purposively. Instntment of analysis is Importanceand Performance Analysis. Results of analysis showed that logistic cent.er meet the criteria.,connected 1mth the transportation SIJSfems, should the wide land area located near the harbor, connectedto the container terminals, high container slzip capacihj, minilnbilihJ of prinzan; commodities,advanced of infomzation and communication teclznologies.Keywords: wgistic cent.er development.
Hepatoprotective Activity of Ethanol Extract of Mobe Leaves (Artocarpus lacucha Buch-Ham.) on Total Bilirubin, ALT, and AST Levels, and Macropathology of Liver in Rats Induced by Carbon Tetrachloride Lubis, Meiva Amelia; Dalimunthe, Aminah; Sitorus, Panal; Satria, Denny; Lubis, Arga
Viva Medika Vol 17 No 3 (2024)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i3.1490

Abstract

This study evaluates the hepatoprotective effects of ethanol extract of mobe leaves (Artocarpus lacucha Buch-Ham.) in rats induced with carbon tetrachloride (CCl4). The objective was to determine the extract's efficacy in reducing liver damage markers, specifically total bilirubin, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) levels, and to assess liver macropathology. The ethanol extract was prepared by maceration using 96% ethanol. Results showed that administering 400 mg/kg body weight (BW) of the extract significantly reduced total bilirubin, ALT, and AST levels in CCl4-induced rats. Additionally, liver macropathology observations indicated improved liver conditions in the treatment group. Phytochemical screening revealed bioactive compounds like flavonoids, alkaloids, tannins, saponins, triterpenoids, and glycosides, which are potential antioxidants and hepatoprotective agents. The significant contribution of this research is providing a scientific basis for using mobe leaf extract as a natural hepatoprotective agent, highlighting its potential for safe and effective herbal medicine. Further research and clinical trials are recommended to validate these findings and explore the extract's therapeutic applications.
Evaluation of Antyhipercholesterolemic Effect of Allium cepa L. var cepa in Atherogenic Induced Rats Lumban Gaol, Nurahmi; Yuandani; Sitorus, Panal
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 4 No. 1 (2021): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v4i1.5381

Abstract

Fermented onion is a type of onion that produced by heating onion bulbs at high temperature for 15 days by fermenter machine. This research is expected to produce new alternatives therapy for reducing cholesterol from onions especially Allium cepa L. var cepa. In this experimental laboratory used 25 male white rats that divided into five groups, group I: negatif control, group II: positif control (Atorvastatin), group III: 100 mg/Kg body weight (bw) of fermented onion extact, group IV: 200 mg/Kg bw of fermented onion extract and group V: 300 mg/Kg bw of fermented onion extract. The Rats was feeding by an atherogenic diet to makes them hypercholesterolemia before treatment for 7th days, 14th days and 21st days. All of data were analyzed by ANOVA method (significant 0,05). The result concludes that of all the doses tested, fermented onion extract of Allium cepa L. var cepa with a dose of 200 mg/Kg bw has the highest effect in decreasing total cholesterol levels of hypercholesterolemia rats (Rattus novergicus).
Aktivitas Antibakteri Ekstrak Etanol Herba Cyperus Rotundus L. Terhadap Escherichia Coli dan Staphylococcus Aureus Sunariati, Sunariati; Masfria, Masfria; Sitorus, Panal
Jurnal Ners Vol. 10 No. 1 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.52125

Abstract

Rumput teki (Cyperus rotundus L.) family Cyperaceae dikenal sebagai gulma yang mengandung metabolit sekunder yang berpotensi sebagai antibakteri. Data ilmiah pada bagian herba rumput teki masih terbatas. Penelitian ini menganalisis aktivitas antibakteri ekstrak etanol terhadap Escherichia coli dan Staphylococcus aureus. Ekstraksi herba rumput teki (Cyperus rotundus L.) dilakukan dengan cara maserasi menggunakan pelarut etanol. Uji aktivitas antibakteri dilakukan secara in vitro menggunakan metode difusi dengan konsentrasi 400, 300, 200, 100, 50, 40, 30, 20, 10, 5, 2.5, dan 2 mg/mL serta penentuan konsentrasi hambat minimum (KHM). Hasil menunjukkan kadar air pada simplisia herba rumput teki (Cyperus rotundus L.) sebesar 6,63%. Skrining fitokimia menunjukkan ekstrak etanol mengandung alkaloid, flavonoid, saponin, tanin, glikosida, serta steroid/triterpenoid. Hasil uji menunjukkan ekstrak etanol herba rumput teki memiliki aktivitas antibakteri yang efektif pada konsentrasi 400 mg/mL dengan zona hambat 14.6 ± 0.07 mm untuk Escherichia coli dan 13.2 ± 0.07 mm untuk Staphylococcus aureus. Konsentrasi hambat minimum (KHM) ekstrak etanol herba rumput teki terhadap terhadap Escherichia coli dan Staphylococcus aureus diperoleh pada konsentrasi 2,5 mg/mL. Penelitian ini mendukung bahwa herba rumpu teki (Cyperus rotundus L.) berpotensi sebagai sumber antibakteri alami.