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All Journal Indonesian Journal of Pharmaceutical Science and Technology JURNAL PENGABDIAN KEPADA MASYARAKAT Journal of Islamic Pharmacy Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Journal of Islamic Medicine FITOFARMAKA: Jurnal Ilmiah Farmasi JFIOnline Indonesian Journal of Halal Research Science Midwifery Jurnal Ilmiah Medicamento Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Bioscientist : Jurnal Ilmiah Biologi Farmasis: Jurnal Sains Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian JURNAL PENGABDIAN PENDIDIKAN MASYARAKAT (JPPM) Medical Sains : Jurnal Ilmiah Kefarmasian
Novia Maulina
Program Studi Farmasi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Islam Negeri Maulana Malik Ibrahim Malang
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Efek Antiinflamasi Ekstrak dan Tablet Daun Kenitu (Chrysophyllum cainito L. ) pada Tikus Wistar (Rattus norvegicus) Ma'arif , Burhan; Sholekhah, Syafirda Arma'atu; Fuadi, Muhammad Nauval Nadhirul; Dianti, Meilina Ratna; Suryadinata , Arief; Maulina, Novia
FARMASIS: Jurnal Sains Farmasi Vol 5 No 1 (2024): Farmasis: Jurnal Sains Farmasi Vol 5. No. 1 (2024)
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v5i1.8614

Abstract

Pendahuluan : Inflamasi pada persendian akibat kerusakan tulang rawan merupakan ciri dari osteoarthritis (OA). Osteoarthtritis adalah suatu penyakit degeneratif terkait dengan rendahnya kadar estrogen dalam tubuh. Senyawa fitoestrogen memiliki struktur yang sama seperti estrogen, sehingga fitoestrogen dapat menjadi alternatif dalam meredakan inflamasi pada OA. Daun kenitu (Chrysophyllum cainito L.) salah satu tanaman yang memiliki kandungan senyawa fitoestrogen. Tujuan: Untuk membuktikan ekstrak etanol 70 persen (EDC) dan tablet (TDC) yang diformulasikan dari daun C. cainito  dapat mengurangi efek inflamasi pada tikus wistar jantan. Metode: Aktivitas antiinflamasi EDC dan TDC  kemudian diuji pada tikus menggunakan metode edema kaki tikus yang diinduksi karagenan dengan dosis 4,05, 8,1, dan 16,2 mg tiap 200gBB tikus per hari untuk EDC, sedangkan untuk TDC 24,3, 48,6, dan 97,2 mg tiap 200gBB tikus per hari. Setelah pemberian masing-masing sampel selama 30 menit, tikus diinduksi secara subplantar dengan karagenan 1 persen  kemudian diamati edema pada telapak kaki tikus selama 6 jam.  Hasil: EDC dan TDC menunjukkan aktivitas antiinflamasi, dengan dosis optimal untuk EDC adalah 4,05 mg tiap 200gBB sedangkan, dosis optimal untuk TDC adalah 48,6 mg tiap 200gBB, sehingga menghasilkan persentase penghambatan edema pada tikus. Kesimpulan: Hasil tersebut menunjukkan bahwa CLE dan CLT mempunyai efek anti inflamasi sehingga berpotensi untuk dikembangkan sebagai obat alternatif anti OA.
Overview of The Level of Outpatient Satisfaction with Pharmaceutical Services in The Pharmacy Room Jenggawah Sub-District Public Health Jember Regency Maulina, Novia; Sugihantoro, Hajar; Syahrir, Achmad; Pratiwi, Nurvita Cindy Dwi
Journal of Islamic Pharmacy Vol 8, No 2 (2023): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v8i2.24572

Abstract

Health is one of the important things for human life as a supporting factor of the quality of human life. Public health center is the first health facility for the community as an effort to improve health with several health services. One of the health services at the Public health center is pharmaceutical services whose activities are directly responsible for preventing the misuse of drugs against patients by providing the best service so that patient satisfaction arises. The purpose of this research was to determine the level of satisfaction of outpatients with pharmaceutical services in the pharmacy room of the Public health center at Jenggawah sub- district, Jember Regency. This type of research was descriptive research with a quantitative approach. The sampling method uses a nonprobability sampling method with purposive sampling techniques. Samples were obtained 100 respondents. This study refers to service quality (servqual) questionnaire instrument using a Likert scale satisfaction calculation and processed using SPSS 25. The results of the research on the level of patient satisfaction with pharmaceutical services on the pharmacy room's appearance were 78.95% (very satisfied), drug information services 80.33% (very satisfied), The pharmacist hospitality was 84.75% (very satisfied), the speed and accuracy of the officers were 80% (very satisfied), and at the indicators of drug availability 74.25% (medium). So that the majority of outpatient satisfaction with pharmaceutical services in the Pharmacy Room of the Public health center at Jenggawah Sub-district, Jember Regency is in the satisfied category.
Acute Toxicity of 70% Ethanol Extract of Kenitu (Chrysophyllum cainito L.) Leaves of Wistar Rats (Rattus norvegicus) Maulina, Novia; Fawzia, Rachma Izza; Firdausy, Alif Firman; Quintão, Roberto Doutel; Ma'arif, Burhan
Journal of Islamic Pharmacy Vol 9, No 1 (2024): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v9i1.27019

Abstract

The postmenopausal phase, which results in a lack of estrogen levels and is one of the triggers of menopausal symptoms, contributes to the elderly's cognitive function decline. This condition can also cause joint and bone pain, bladder and urinary tract disorders, and sexual problems. Based on several studies, it is known that kenitu (Chrysophyllum cainito L.) contains phytoestrogen compounds with a structure similar to the hormone estrogen, so kenitu has the potential as an alternative treatment for disease conditions with risk factors for estrogen deficiency. The study was conducted to determine the estimated lethal dose 50 (LD50) value based on the Globally Harmonized System (GHS) classification as well as macroscopic (physical, behavioral, and average weight gain per day) and microscopic (liver and kidney histology) values in Wistar rats against the administration of 70% ethanol extract of kenitu leaves at a dose of 2000 mg/kg body weight (BW). The Up-and-Down Procedure (UDP) acute toxicity test method was used for this study. The maximum dose was 2000 mg/kg BW of ethanol extract from 70% kenitu leaves. The study found that the 70% ethanol extract of kenitu leaves had more than 2000 mg/kg BW LD50 value against Wistar rats. Based on the classification of the GHS, it can be concluded that 70% ethanol extract of kenitu leaves against Wistar rats is classified as low toxicity.
Pengaruh Tingkat Pengetahuan terhadap Perilaku dalam Menggunakan Produk Kosmetik Berlabel Halal pada Mahasiswa Teknik Arsitektur UIN Malang Maulina, Novia; Silmy, Nur Fairus; Sugihantoro, Hajar; Syahrir, Achmad
Journal of Islamic Pharmacy Vol 9, No 2 (2024): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v9i2.26879

Abstract

Indonesia sebagai negara dengan mayoritas penduduk muslim, sepatutnya memenuhi kebutuhan yang mengarah pada keadaan kehalalan suatu produk, salah satunya penggunaan kosmetik yang banyak digunakan masyarakat terutama mahasiswa. Kesadaran dalam menggunakan kosmetik halal ini merupakan akibat dari pemahaman agama yang baik serta edukasi produsen terkait sertifikat halal pada produknya, sehingga masyarakat lebih selektif pada pemilihan produk yang digunakan. Pengetahuan tentang kosmetik halal ini akan mempengaruhi perilaku dalam menggunakan produk kosmetik halal. Tujuan penelitian ini adalah untuk mengetahui tingkat pengetahuan dan perilaku mahasiswa Teknik Arsitektur UIN Malang tentang produk kosmetik halal, serta mengetahui pengaruh tingkat pengetahuan terhadap perilaku dalam menggunakan kosmetik berlabel halal pada mahasiswa Teknik Arsitektur UIN Malang. Metode penelitian bersifat deskriptif kuantitatif. Teknik pengambilan sampel menggunakan non probability sampling yaitu teknik purposive sampling. Hasil analisis data pada 104 responden menunjukkan pada tingkat pengetahuan 73 mahasiswa (70%) memiliki pengetahuan tinggi, 30 mahasiswa (29%) memiliki pengetahuan cukup, dan 1 mahasiswa (1%) memiliki pengetahuan rendah. Pada tingkat perilaku 62 (60%) mahasiswa memiliki perilaku tinggi, 27 mahasiswa (26%) memiliki perilaku cukup, dan 15 mahasiswa (14%) memiliki perilaku rendah. Pengetahuan kosmetik halal berpengaruh signifikan (0,006) terhadap perilaku dalam menggunakan produk kosmetik berlabel halal dengan kekuatan pengaruh sedang 0,388 dan arah positif. Kesimpulan penelitian ini adalah terdapat pengaruh antara pengetahuan tentang kosmetik halal dengan perilaku dalam menggunakan produk kosmetik berlabel halal dengan kekuatan pengaruh tinggi dan arah hubungan yang positif.
Consumer Behavior Analysis as a Form of Pre-market Survey for the Black Pule (Alstonia spectabilis) Antimalarial Tablet Prototype: Analisis Perilaku Konsumen Sebagai Bentuk Survei Pre-market Tablet Prototipe Antimalaria Pule Hitam (Alstonia spectabilis) Taek, Maximus Markus; Ma'arif, Burhan; Maulina, Novia; Muslikh, Faisal Akhmal; Lalong, Paulus Risan Funan
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16986

Abstract

Malaria is a disease caused by the protozoan parasite Plasmodium with a high incidence of spread that is still found in remote tropical places, especially areas around gardens, swamps, forests, and mines such as eastern Indonesia. The commonly used antimalarial drug chloroquine has experienced resistance, encouraging researchers to look for effective alternative treatments. Formulation development of Standardized Herbal Medicine (OHT) from black pule was carried out as a potential new alternative treatment as an antimalarial. Objectives: The purpose of this study was to determine the level of liking and quality assessment or characteristics of the prototype of antimalarial OHT tablets. Methods: The method used in this research is descriptive quantitative which aims to describe 57 panelists' perspective on the product and to analyze product marketing. In this research method includes hedonic test and hedonic quality test which is a series of organoleptic tests and consumer acceptance tests by tasting and observing the product followed by filling out a form according to what is felt and observed. Results: The results obtained from this research, namely the preference test of the overall characteristics of the prototype of antimalarial black pule tablets (Alstonia spectabilis) showed a good sensory impression and characteristics. The positive results obtained from all aspects have illustrated that the panelists have considerable interest in the prototype sample and assess that the prototype tablets are suitable for dissemination to the public. Conclusions: Based on the research, it can be concluded that the prototype of black pule (Alstonia spectabilis) tablets tested through hedonic and hedonic quality tests produced overall good results, characterized by the tendency of panelists to choose "Like" in the hedonic test of sensory impressions and positive values in the hedonic quality test.
Cost-Effectiveness Analysis Penggunaan Antidiabetik Oral pada Pasien Diabetes Melitus Rawat Jalan di RSU Haji Surabaya Rahmadanita, Fathia Faza; Maulina, Novia; Sugihantoro, Hajar; Muhimmah, Ilmiyatul; Saputra, Azian F.
Pharmaceutical Journal of Indonesia Vol. 8 No. 1 (2022)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2022.008.01.5

Abstract

ABSTRAK Pendahuluan: Diabetes melitus adalah penyakit kronis akibat proses metabolisme dalam tubuh yang tidak normal yang ditandai dengan adanya peningkatan kadar glukosa darah melebihi batas normal dalam tubuh. Diabetes melitus membutuhkan perawatan medis secara terus-menerus sehingga biaya medis yang dikeluarkan besar. Tujuan: Untuk mengetahui dan menganalisis efektivitas biaya penggunaan antidiabetik oral pada pasien diabetes melitus tipe 2 rawat jalan di RSU Haji Surabaya. Metode: Penelitian ini adalah penelitian deskriptif observasional dengan data retrospektif berupa rekam medis dan biaya pengobatan pasien rawat jalan dengan penyakit diabetes melitus tipe 2 di RSU Haji Kota Surabaya Periode Juni-November 2021. Analisis data dilakukan menggunakan rumus Average Cost-Effectiveness Ratio (ACER) dan Incremental Cost-Effectiveness Ratio (ICER). Hasil: Didapatkan 70 pasien diabetes melitus tipe 2 dengan penyakit penyerta yang memenuhi kriteria inklusi. Penggunaan terapi antidiabetik oral monoterapi ditemukan pada 11 pasien dan pada terapi antidiabetik oral kombinasi sebanyak 59 pasien. Antidiabetik oral monoterapi yang paling banyak digunakan adalah glimepiride (8,57%), sedangkan pada antidiabetik oral kombinasi adalah kombinasi metformin dan glimepiride (17,14%). Terapi antidiabetik oral monoterapi yang paling cost-effective adalah gliklazid dengan nilai efektivitas sebesar 100%, nilai ACER sebesar Rp 1.331,15. dan nilai ICER Rp. -641,70 dan Rp. -714.52. Sedangkan terapi antidiabetik oral kombinasi yang paling cost-effective adalah kombinasi pioglitazone, metformin dan glimepiride dengan nilai efektivitas 55,56%, nilai ACER sebesar Rp 3.266,34 dan nilai ICER Rp. 1.491,54 dan Rp. 1.654,43. Kesimpulan: Berdasarkan parameter ACER dan ICER, antidiabetik oral monoterapi yang paling cost-effective adalah gliklazid. Sedangkan antidiabetik oral kombinasi yang paling cost-effective adalah kombinasi pioglitazone, metformin dan glimepiride. Kata Kunci: Diabetes melitus, Cost-effectiveness Analysis, ACER, ICER
O-CITRI Soap: Antibacterial Paper Soap Made from Orange Peel (Citrus sinensis L.) and Basil (Ocimum sanctum L.) Fitriyani, Fitriyani; Bustomi, Mochammad Y. A.; Maulina, Novia; Kinasih, Larasati S.; Arriziq, Muhammad A.
Indonesian Journal of Pharmaceutical Science and Technology Vol 11, No 2 (2024)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v11i2.52344

Abstract

Basil (Ocimum sanctum L.) have a dominant content of citral compounds with antibacterial activity. Another plant suspected to contain antibacterial bioactive components is orange peel. Orange peel (Citrus sinensis L) contains phenolic compounds (phenolic acids, flavonones, and polymethoxylated flavones), carotenoids, and ascorbic acid. Phenolic compounds are known to have several activities such as antimicrobial, antioxidant, anticancer, anti-inflammatory, and anti- allergic. The aim of this research is to prove that the combination of orange peel and basil extracts has antibacterial effects against Staphylococcus aureus, which can be formulated as paper soap which is named O-Citri. This research method is experimental, involving the physical and chemical evaluation of the formulation, as well as antibacterial activity testing. The research results show that the combination of orange peel and basil extracts in the paper soap formulation has antibacterial effects. The highest concentration combination for antibacterial activity is F1 with a ratio of orange peel and basil extract at 5%:15%.
Eksplorasi Hubungan Tingkat Pengetahuan Terhadap Kepatuhan Terapi Pasien Hipertensi di UPT Puskesmas Tanjung Batu Kabupaten Karimun Maulina, Novia; Luthfi, Fitrati Hasanah; Inayatilah, Fidia Rizkiah; muslikh, Faisal akhmal
Journal of Islamic Medicine Vol 9, No 1 (2025): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2025
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v9i1.25921

Abstract

Background: Hypertension is a condition where blood pressure exceeds normal levels (120/80mmHg), with systolic blood pressure above 140 mmHg and diastolic blood pressure above 90mmHg. Termed as the "silent killer," hypertension often manifests without symptoms and is a leading cause of death in Indonesia. The prevalence of hypertension in the Riau Islands Province reached 25.85% in 2018, with Karimun Regency ranking second. Objectif: This study aims to assess the relationship between knowledge and adherence to antihypertensive medication among hypertensive patients at UPT Puskesmas Tanjung Batu, Karimun, in 2022. Methods: This observational study employs a Cross-sectional design. Data were collected from March to May 2022 from 90 respondents using a questionnaire. The sampling method used was consecutive sampling. Data analysis involved univariate and bivariate analyses with the Spearman rank test (significance level 0.005). Results: The majority of respondents were female (71%), aged 46-55 years (43%), with an educational background of elementary school (62%). On average, they had suffered from hypertension for less than 5 years (56%), and the primary source of information was from doctors (81%). Knowledge level was sufficient (49%), while medication adherence was low (83%). Statistical analysis indicated a significant relationship (p=0.001) and alignment between knowledge and adherence among hypertensive patients at UPT Puskesmas Tanjung Batu, Karimun, with a moderate correlation (r=0.343). Conclusion: There is a significant relationship between knowledge and adherence to antihypertensive medication among hypertensive patients.
Hubungan Faktor Sosiodemografi dengan Perilaku Swamedikasi Obat Analgesik pada Masyarakat Kota Malang Yusuf, Muhammad Faishal; Sugihantoro, Hajar; Hakim, Abdul; Maulina, Novia; Ummah, Syifaul Khoiro
Jurnal Ilmiah Medicamento Vol 11 No 2 (2025): Jurnal Ilmiah Medicamento (In progress)
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i2.10708

Abstract

The prevalence of self-medication among the population of Malang City reached 64.35% in 2022. This figure indicates a considerable potential risk, particularly related to inappropriate medication practices. Analgesics are among the most used drugs for pain relief through self-medication. Improper use of analgesics may lead to adverse effects, including gastrointestinal disturbances, hypersensitivity reactions, and damage to the kidneys and liver. This study aims to examine self-medication behavior involving analgesics and to analyze the relationship between respondents’ sociodemographic factors and such behavior. The research employed quantitative analytic observational design with a cross-sectional approach and survey method. Sampling was conducted using a non-probability sampling technique, involving 100 respondents who met the inclusion and exclusion criteria. Data analysis was performed using non-parametric statistical tests, namely the Chi-Square test for gender, occupation, and residence variables, and the Spearman Rank test for age, income, and education level. The results showed that the self-medication behavior with analgesics among the people of Malang City was categorized as “moderate,” with a prevalence of 72%. Statistical analysis revealed significant associations between age, income, education level, and residential area with analgesic self-medication practices. Conversely, gender and occupation did not show statistically significant relationships. These findings provide a foundation for developing targeted educational strategies and public health policies to promote safer and more rational self-medication practices.
The effect of providing educational videos on the level of knowledge and attitudes of the Batu City community regarding the use of halal-labeled medicines Maulina, Novia; Syahrir, Ach; Lestari, Ludy Wiji; Rahmandhani, Farhana Rezi Gita
Science Midwifery Vol 12 No 2 (2024): June: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i2.1529

Abstract

Indonesia is the country with the largest Muslim population in the world. For a Muslim, consuming halal products is a necessity and obligation as a form of faith in Allah SWT. However, the awareness of the Muslim community in paying attention to the halalness of medicinal products still needs to be increased. Education regarding halal-labeled medicines is an effort that can be made to increase public knowledge about halal-labeled medicines. Increasing a person's knowledge can form a positive attitude so that public awareness about the importance of halal-labeled medicines can increase. This research aims to find out whether providing educational videos affects the level of knowledge and attitudes of the people of Batu City regarding the use of halal-labeled medicines. This research is a pre-experimental quantitative research with a one-group pretest-posttest design. The research sample was taken using a purposive sampling technique, and the number of research respondents was 100. The results of the research on the normality test showed that the data on the knowledge and attitude variables were not normally distributed, so the Wilcoxon test was carried out, which showed that there were differences in the level of knowledge and attitudes of respondents before and after being given the educational video with a significance value (p-value ˂ 0.05). This research concludes that providing educational videos influences the knowledge and attitudes of the people of Batu City regarding halal-labeled medicines.
Co-Authors Abdul Hakim Abdul Hakim Abdul Malik Setiawan Abdul Wafi Almay Abidzar Elpasha Andayani, Nurita Arief Suryadinata Arriziq, Muhammad A. Aszari, Efendi H. Azzahra, Azizah Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Bustomi, Mochammad Y. A. Cindy Natasya Dhani Wijaya Dian Ratih Laksmitawati Fadilla, Rahma Nur Fahrul Rizki Faisal Akhmal Muslikh Fathia Faza Rahmadanita Fawzia, Rachma Izza Fidia Rizkiah Inayatilah Firdaus, Natasya Octavia Putri Firdausy, Alif Firman Fitriyani Fitriyani Fricananta, Salma Salsabila Fuadi, Muhammad Nauval Nadhirul Ginanjar Putri Nastiti Humaira Ramzi Hurriyatul Zulfa Kamelin, Badira Khoirunnisa, Zahra Kinasih, Larasati S. Lalong, Paulus Risan F. Lestari, Ludy Wiji Luthfi, Fitrati Hasanah M. Yogi Riyantama Isjoni Ma'arif , Burhan Ma'arif, Burhan Ma’arif, Burhan Mangestuti Agil Ma’arif, Burhan Meilina Ratna Dianti Mohammad Alfin Sammah Muhammad Husnul Wafa Muhimmah, Ilmiyatul Nabila Asha Rahmita Nasichuddin, Achmad Nicotiana, Diah Ayu Nurwijayanti Prameswari, Fadila A. Pratiwi, Nurvita Cindy Dwi Quintão, Roberto Doutel Rahmandhani, Farhana Rezi Gita Rani Azzahara Sampurno Sampurno Saputra, Azian F. Sawjana, Oashiva H. Sholekhah, Syafirda Arma'atu Silmy, Nur Fairus Subiyakto, Erlangga Sufi Sugihantoro Sugihantoro Syahrir, Ach Syahrir, Achmad Taek, Maximus M. Taek, Maximus Markus Tanaya Jati Dharma Dewi Ummah, Syifaul Khoiro Winayah, Mesri Ananta Yuan Tamara Yusuf, Muhammad Faishal