Claim Missing Document
Check
Articles

Found 27 Documents
Search

Aktivitas Afrodisiak in Vivo Ekstrak Etanol 70% Akar Lelak (Uvaria rufa Blume.) Pada Mencit (Mus musculus) Jantan Taek, Maximus M.; Muslikh, Faisal Akhmal; Maulina, Novia; Sawjana, Oashiva H.; Azzahra, Azizah; Aszari, Efendi H.; Prameswari, Fadila A.; Ma’arif, Burhan
Bioscientist : Jurnal Ilmiah Biologi Vol. 12 No. 2 (2024): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i2.13025

Abstract

Sexual arousal is an important aspect to achieve a harmonious sex life, but often disorders in normal sexual function disrupt the harmony of household relationships. One alternative natural ingredient that has the potential as an aphrodisiac agent is Lelak (Uvaria rufa) which is traditionally used by the people of East Nusa Tenggara (NTT), Indonesia, to overcome sexual dysfunction in men. This study aims to evaluate the safety and effectiveness of 70% ethanol extract of Uvaria rufa roots in vivo. This study is an experimental study to test the effectiveness of 70% ethanol extract of Uvaria rufa roots in vivo. This study was conducted with an initial stage, namely 70% ethanol extract of Uvaria rufa roots obtained through maceration, then the aphrodisiac activity was measured through the parameters of the number of leydig cells and the weight of the testes of male mice (Mus musculus).The results showed that the administration of the extract with an LD50 value of 2108 μg/ml which is included in the Relatively Harmless category, while group P2 with a dose of 0.85 mg/20g BB/day was stated as the optimal dose (p<0.05 against the negative control) for aphrodisiac activity in measuring testicular weight and the number of Leydig cells. Therefore, administration of 70% ethanol extract of Uvaria rufa roots at a dose of 0.85 mg/20g BW/day is the optimal dose for aphrodisiac activity.
Formulasi Sabun Mandi Cair Berbasis Virgin Coconut Oil (VCO): Optimalisasi Pemanfaatan Produk Lokal Untuk Perawatan Kulit dan Pencegahan Dehidrasi Maulina, Novia; Muslikh, Faisal Akhmal; Nastiti, Ginanjar Putri; Fadilla, Rahma Nur; Winayah, Mesri Ananta; Kamelin, Badira; Firdaus, Natasya Octavia Putri; Fricananta, Salma Salsabila; Dewi, Tanaya Jati Dharma
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 1 (2025): March
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i1.14160

Abstract

Skin dehydration is a common issue affecting 40–50% of the adult population, resulting in dry, rough, and dull skin, as well as itching, irritation, and premature aging. The "back to nature" trend has increased interest in natural skincare products that are more environmentally friendly and gentler on the skin. Virgin coconut oil (VCO) is a popular natural ingredient known for its ability to maintain skin moisture and provide protection. This study aims to develop a liquid soap formulation using VCO to address skin dehydration. The research methods included formulation and evaluation of liquid soap through organoleptic testing, foam stability, specific gravity, pH, as well as hedonic and irritation tests. The results showed that: (1) Formula III met all physical evaluation parameters, including organoleptic characteristics, foam stability and height, specific gravity, and pH, in accordance with SNI standards; (2) Formula III was the most preferred by panelists in the hedonic test and caused no skin irritation based on irritation test results. Therefore, Formula III can be concluded as the optimal formulation for VCO-based liquid bath soap.
SOSIALISASI DAN EDUKASI DAGUSIBU PADA KELOMPOK IBU RUMAH TANGGA DI KECAMATAN DAU Maulina, Novia; Hakim, Abdul; Fitriyani, Fitriyani; Ma'arif, Burhan
Jurnal Pengabdian Pendidikan Masyarakat (JPPM) Vol 4 No 1 (2023): Jurnal Pengabdian Pendidikan Masyarakat (JPPM)
Publisher : LPPM UNIVERSITAS MUHAMMADIYAH MUARA BUNGO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52060/jppm.v4i1.1056

Abstract

Health promotion is the process by which a community makes efforts to improve its ability to optimize the factors that affect health. In addition to positive impacts, advances in science and technology in the pharmaceutical industry also have negative impacts, one of which is obtaining, using, storing, and disposing of drugs in the wrong way. “Dapatkan, Gunakan, Simpan, Buang” (DAGUSIBU) is a Drug Awareness Family Movement initiated by the Indonesian Pharmacists Association (IAI) in an effort to provide public understanding and awareness of the correct use of drugs. This community service was carried out with the aim of socializing and educating the housewives' community group in Dau sub-district, Malang Regency, about DAGUSIBU. The method used is quantitative with a quasi-experimental design with a one-group pretest and posttest with active and participatory learning methods through door-to-door socialization activities with media leaflets. The results show that most respondents are aged 31–35 years (23.8%), and the distribution of DAGUSIBU drug knowledge among respondents has increased by 66.6% after socialization and education activities.
Optimasi Kombinasi Ramuan Etnomedisin Penumbuh Rambut Nusa Tenggara Timur Menggunakan Orthogonal Stimulus Response Method Pada Kepadatan Rambut Mencit (Mus musculus) Taek, Maximus M.; Megawati, Dewi Sinta; Subiyakto, Erlangga Sufi; Khoirunnisa, Zahra; Maulina, Novia; Muslikh, Faisal Akhmal; Ma’arif, Burhan
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 4 (2025): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i4.18301

Abstract

This study aimed to optimize a traditional ethnomedicinal formulation from East Nusa Tenggara (RENTT) as a natural hair-growth candidate and to evaluate its antioxidant activity and biological effectiveness using an alopecia model. A true experimental design was applied using the Taguchi–Orthogonal Stimulus Response Method (OSRM) to determine the optimal combination of five plant extracts, namely Aleurites moluccanus, Hibiscus rosa-sinensis, Ficus benjamina, Polyscias scutellaria, and Hibiscus tiliaceus. In vitro optimization was conducted using the DPPH radical scavenging assay with a Taguchi L27 orthogonal array design. The optimal formulation was subsequently evaluated in vivo using male mice (Mus musculus) with croton oil–induced alopecia. Hair growth effectiveness was assessed based on hair density percentage through histomorphometric analysis with hematoxylin–eosin staining. The results demonstrated that the optimal RENTT formulation exhibited very strong antioxidant activity with an IC₅₀ value of 27.46 ppm. Taguchi analysis identified F. benjamina as the most influential factor in determining formulation performance. In vivo evaluation showed that the RENTT-treated group achieved the highest hair density (49.45 ± 4.70), which was significantly higher than that of the positive control, negative control, and normal control groups. In conclusion, the optimized RENTT formulation demonstrates strong antioxidant properties and a significant stimulatory effect on hair growth, indicating its promising potential as a natural cosmeceutical product based on the local wisdom of East Nusa Tenggara.
The Influence of Perception of Halal Labels and Brand Image on Cosmetic Purchasing Decisions Among Millennials Hakim, Abdul; Sugihantoro, Hajar; Maulina, Novia; Nasichuddin, Achmad; Setiawan, Abdul Malik; Nicotiana, Diah Ayu
Indonesian Journal of Halal Research Vol. 6 No. 2 (2024): August
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ijhar.v6i2.37077

Abstract

The cosmetics industry consistently requires up-to-date research to develop effective marketing strategies that attract consumers and build their trust. This research aims to analyze how Millennials perceive halal labels and brand image in relation to their purchasing decisions for cosmetics. The study utilized an associative research method with a quantitative approach, employing purposive sampling and a questionnaire as its instrument. Data was processed using structural equation modeling-partial least squares (SEM-PLS) analysis. The findings indicate a strong positive correlation between the perception of halal labels and Millennials' purchasing decisions for cosmetics, as halal certification is a crucial factor for this demographic. Additionally, the study found that a positive brand image also significantly influences purchasing decisions, as consumers prefer products that are recognized for their quality, safety, and popularity. The practical implications for the cosmetics industry are evident: understanding the factors that drive purchasing decisions can help companies make the best strategic choices. It is recommended that companies consistently maintain halal certification on their products and focus on building a strong brand image, as both factors play a critical role in influencing consumer decisions.
SOSIALISASI DAN EDUKASI DAGUSIBU PADA KELOMPOK IBU RUMAH TANGGA DI KECAMATAN DAU Maulina, Novia; Hakim, Abdul; Fitriyani, Fitriyani; Ma'arif, Burhan
Jurnal Pengabdian Pendidikan Masyarakat (JPPM) Vol 4 No 1 (2023): Jurnal Pengabdian Pendidikan Masyarakat (JPPM)
Publisher : LPPM UNIVERSITAS MUHAMMADIYAH MUARA BUNGO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52060/jppm.v4i1.1056

Abstract

Health promotion is the process by which a community makes efforts to improve its ability to optimize the factors that affect health. In addition to positive impacts, advances in science and technology in the pharmaceutical industry also have negative impacts, one of which is obtaining, using, storing, and disposing of drugs in the wrong way. “Dapatkan, Gunakan, Simpan, Buang” (DAGUSIBU) is a Drug Awareness Family Movement initiated by the Indonesian Pharmacists Association (IAI) in an effort to provide public understanding and awareness of the correct use of drugs. This community service was carried out with the aim of socializing and educating the housewives' community group in Dau sub-district, Malang Regency, about DAGUSIBU. The method used is quantitative with a quasi-experimental design with a one-group pretest and posttest with active and participatory learning methods through door-to-door socialization activities with media leaflets. The results show that most respondents are aged 31–35 years (23.8%), and the distribution of DAGUSIBU drug knowledge among respondents has increased by 66.6% after socialization and education activities.
Orthogonal Stimulus Response Method Optimization of Essential Oil Combinations from Magnolia alba, Cryptocarya massoia, and Melaleuca alternifolia for Antioxidant and Anti-Cutibacterium acnes Activities Ayudianti, Prida; Rahmayanti, Mayu; Maulina, Novia; Muslikh, Faisal Akhmal; Aluzia, Aufary Naurah; Azzahra, Fatimah; Ma’arif, Burhan
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 1 (2026): March
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i1.20029

Abstract

This study aimed to optimize a combination of white champaca oil (Magnolia alba), massoia bark oil (Cryptocarya massoia), and tea tree oil (Melaleuca alternifolia) as antibacterial and antioxidant agents using the Orthogonal Stimulus Response Method (OSRM) with a Taguchi L4 (2³) design. Antibacterial activity was evaluated using the well diffusion method against C. acnes, while antioxidant activity was assessed using the DPPH radical scavenging assay. The results demonstrated that all variations of the CMT oil combinations exhibited moderate antibacterial activity and strong antioxidant activity, with IC₅₀ values ranging from 50 to 100 µg/mL. Based on the Taguchi analysis, the optimal combination for antibacterial activity was obtained at concentrations of 6% champaca oil, 0.4% massoia oil, and 5% tea tree oil. Meanwhile, the most optimal and stable antioxidant activity was achieved with the combination at concentrations of 75:100:100 ppm. In both assays, champaca oil was identified as the most influential factor affecting the observed biological responses. These findings indicate that the CMT oil combination has promising potential as a multifunctional therapeutic candidate for cosmetic and pharmaceutical applications, particularly as a topical nanoemulsion face mist for the management of acne while simultaneously preventing skin damage caused by free radicals.
Co-Authors Abdul Hakim Abdul Hakim Abdul Malik Setiawan Abdul Wafi Almay Abidzar Elpasha Aluzia, Aufary Naurah Andayani, Nurita Arief Suryadinata Arriziq, Muhammad A. Aszari, Efendi H. Azzahra, Azizah Burhan Ma&#039;arif Burhan Ma'arif Burhan Ma'arif Bustomi, Mochammad Y. A. Cindy Natasya Dhani Wijaya Dian Ratih Laksmitawati Fadilla, Rahma Nur Fahrul Rizki Faisal Akhmal Muslikh Fathia Faza Rahmadanita Fatimah Azzahra Fawzia, Rachma Izza Fidia Rizkiah Inayatilah Firdaus, Natasya Octavia Putri Firdausy, Alif Firman Fitriyani Fitriyani Fricananta, Salma Salsabila Fuadi, Muhammad Nauval Nadhirul Ginanjar Putri Nastiti Humaira Ramzi Hurriyatul Zulfa Kamelin, Badira Khoirunnisa, Zahra Kinasih, Larasati S. Lalong, Paulus Risan F. Lestari, Ludy Wiji Luthfi, Fitrati Hasanah M. Yogi Riyantama Isjoni Ma'arif , Burhan Ma'arif, Burhan Ma’arif, Burhan Mangestuti Agil Mayu Rahmayanti Ma’arif, Burhan Meilina Ratna Dianti Mohammad Alfin Sammah Muhammad Husnul Wafa Muhimmah, Ilmiyatul Nabila Asha Rahmita Nasichuddin, Achmad Nicotiana, Diah Ayu Nurwijayanti Prameswari, Fadila A. Pratiwi, Nurvita Cindy Dwi Prida Ayudianti Quintão, Roberto Doutel Rahmandhani, Farhana Rezi Gita Rani Azzahara Sampurno Sampurno Saputra, Azian F. Sawjana, Oashiva H. Sholekhah, Syafirda Arma'atu Silmy, Nur Fairus Subiyakto, Erlangga Sufi Sugihantoro Sugihantoro Syahrir, Ach Syahrir, Achmad Taek, Maximus M. Taek, Maximus Markus Tanaya Jati Dharma Dewi Ummah, Syifaul Khoiro Winayah, Mesri Ananta Yuan Tamara Yusuf, Muhammad Faishal