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All Journal CHEMPUBLISH JOURNAL Majalah Farmaseutik Pharmasipha Jurnal Kreativitas PKM Jurnal Farmasi dan Sains Indonesia (JFSI) Gemakes: Jurnal Pengabdian Kepada Masyarakat Jurnal Teknik Kimia dan Lingkungan PCJN Pharmaceutical and Clinical Journal of Nusantara Parahyangan Economic Development Review (PEDR)
Putri, Amalia Eka
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Energy Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Uji Efektivitas Antioksidan Moisturizer Ekstrak Daun Randu (Ceiba Pentandra (L.) Gaertn.) dengan Metode DPPH Muadifah, Afidatul; Tilarso, Dara Pranidya; Putri, Amalia Eka; Sowe, Momodou Salieu
Chempublish Journal Vol. 8 No. 1 (2024): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v8i1.33234

Abstract

Dry skin can often cause psychological discomfort. Moisturizer is a preparation that is used to improve dry skin. Kapok plant (Ceiba pentandra L. Gaertn) can be used as an active ingredient of moisturizer and can be used as a treatment, where the chemical content in kapok leaves are flavonoids, saponins, alkaloids, phenolic compounds, tannins and terpenoids as antioxidants. This study aims to determine the antioxidant activity of kapok leaf extract and moisturizer preparations with DPPH method using UV-Vis spectrophotometer, physical quality of preparations and antioxidant activity of moisturizer preparations using DPPH method. Kapok leaf extract was made in various concentrations, namely 20 ppm, 40 ppm and 60 ppm. The IC50 value of kapok leaf extract is 67.4007 ppm which has strong antioxidant activity. Then variations in the concentration of kapok leaf extract were put into the formulation of moisturizer preparations, the results of moisturizer preparations of kapok leaf extract and vitamin C met the requirements of the physical quality test. The moisturizer preparation was continued and tested for antioxidant activity using the DPPH method with ascorbic acid as a comparison. The results of the IC50 value on the kapuk leaf extract moisturizer preparation are 110.065 ppm which is classified as having moderate antioxidant activity and while the vitamin C moisturizer preparation is 9.8417 ppm which is classified as having very strong antioxidant activity.
Penguatan Kualitas Kesehatan Masyarakat dan Perekonomian di Desa Wates Tulungagung Berbasis Kearifan Lokal Berupa Jamu Brotowali Martha, Rahma Diyan; Danar, Danar; Putri, Amalia Eka; Setyaningrum, Dyah; Nurin, Wachidatun; Fadila, Natasya Nurul; Widodo, Wimbuh Tri
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 11 (2024): Volume 7 No 11 (2024)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i11.17122

Abstract

ABSTRAK Kegiatan ini dilakukan di Desa Wates, Kecamatan Sumbergempol, Kabupaten Tulungagung, untuk menangani minimnya pemanfaatan tanaman herbal, khususnya brotowali, yang memiliki potensi besar sebagai obat tradisional. Tujuan kegiatan ini adalah untuk mengevaluasi dampak program pemberdayaan masyarakat terkait pemanfaatan tanaman herbal ini. Metode penelitian meliputi penyuluhan, pelatihan, dan pendampingan dalam pembuatan jamu, serta penanaman tanaman herbal di pekarangan rumah. Hasil penelitian menunjukkan peningkatan signifikan dalam pengetahuan dan minat masyarakat tentang tanaman herbal dan pembuatan jamu. Sebelum program, 40% responden memiliki tanaman herbal di pekarangan rumah, sedangkan setelah program, 100% responden melaporkan adanya tanaman herbal di pekarangan mereka. Keinginan untuk menanam tanaman herbal juga meningkat dari 80% menjadi 100%. Kesimpulan dari penelitian ini adalah bahwa program pemberdayaan masyarakat berhasil meningkatkan pengetahuan, keterampilan, dan motivasi masyarakat dalam memanfaatkan tanaman herbal. Kata Kunci: Pemberdayaan Masyarakat, Tanaman Herbal, Brotowali, Pembuatan Jamu  ABSTRACT This activity was carried out in Wates Village, Sumbergempol District, Tulungagung Regency, to address the minimal use of herbal plants, especially brotowali, which has great potential as a traditional medicine. The aim of this activity is to evaluate the impact of community empowerment programs related to the use of this herbal plant. Research methods include counseling, training and assistance in making herbal medicine, as well as planting herbal plants in the home yard. The research results show a significant increase in people's knowledge and interest about herbal plants and making herbal medicine. Before the program, 40% of respondents had herbal plants in their yard, while after the program, 100% of respondents reported having herbal plants in their yard. The desire to plant herbal plants also increased from 80% to 100%. The conclusion of this research is that the community empowerment program has succeeded in increasing people's knowledge, skills and motivation in using herbal plants.  Keywords: Community Empowerment, Herbal Plants, Brotowali, Making Herbal Medicine.
Pengaruh Ekspektasi Kebijakan Fiskal terhadap Peningkatan Efektivitas Ekspektasi Kebijakan Moneter dalam Pengendalian Inflasi di Indonesia Putri, Amalia Eka
PARAHYANGAN ECONOMIC DEVELOPMENT REVIEW Vol 3 No 2 (2024): Parahyangan Economic Development Review
Publisher : Jurusan Ilmu Ekonomi Universitas Katolik Parahyangan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26593/yfvprm97

Abstract

Penelitian ini bertujuan untuk menganalisis peran kebijakan fiskal dalam meningkatkan efektivitas kebijakan moneter dalam pengendalian inflasi. Analisis penelitian ini dilakukan menggunakan metode ordinary least square (OLS) pada data kuartalan periode 2004Q1-2022Q4. Hasil penelitian menunjukkan bahwa variabel independent yang digunakan berpengaruh terhadap inflasi sebesar 86,8307% (ditunjukkan oleh nilai R-squared). Secara spesifik, ditemukan bahwa ekspektasi inflasi dan output gap berpengaruh positif dan signifikan terhadap inflasi, berbeda dengan tingkat suku bunga riil yang menunjukkan pengaruh positif namun tidak signifikan terhadap pengendalian inflasi. Lalu ekspektasi inflasi dari kebijakan fiskal menunjukkan pengaruh positif namun tidak signifikan terhadap inflasi. Sementara itu, interaksi antara kebijakan moneter dan kebijakan fiskal menegaskan pentingkan kedua kebijakan tersebut berkoordinasi dalam mengelola stabilitas harga. Namun, hasil penelitian ini masih memiliki keterbatasan dimana belum sepenuhnya interaksi kebijakan moneter dan kebijakan fiskal terhadap pengendalian inflasi dibahas dan dianalisis secara mendalam menggunakan teknik analisis yang sesuai.
Permintaan Uang dengan Mempertimbangkan Endogenous Money di Indonesia Jonathan, Brian; Butarbutar, Glen Oloan; Putri, Amalia Eka; Sukma, Davit Dirgantara
PARAHYANGAN ECONOMIC DEVELOPMENT REVIEW Vol 4 No 1 (2025): Parahyangan Economic Development Review
Publisher : Jurusan Ilmu Ekonomi Universitas Katolik Parahyangan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26593/trj1cg14

Abstract

Dalam penelitian ini penulis bertujuan untuk melihat sisi endogenous money pada money demand di Indonesia. Terdapat perbedaan dari ekonomi yang memiliki endogenous money dengan yang tidak berdasarkan dari pemenuhan permintaan uang dari kredit. Kami memakai OLS dan menemukan bahwa di Indonesia tidak terdapat endogenous money dikarenakan peraturan perbankan. Penelitian ini juga menunjukkan model money demand yang sudah disederhanakan agar dapat diregresikan. Penelitian ini memiliki implikasi dari periode waktu hingga kurangnya tinjauan literatur.
In Vitro Antibacterial Activity and Minimum Inhibitory Concentration of Citrus aurantifolia Lime Peel Ethanolic Extract against Propionibacterium acnes Putri, Amalia Eka; Negara, Sri Bintang Sahara Mahaputra Kusuma
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 1 No. 03 (2023): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v2i02.18

Abstract

Propionibacterium acnes (syn. Cutibacterium acnes) is the principal gram-positive anaerobe implicated in acne vulgaris through lipolysis, follicular obstruction, and pro-inflammatory cytokine induction. Rising antibiotic resistance among P. acnes strains necessitates plant-derived alternatives. This study evaluated the in vitro antibacterial activity and minimum inhibitory concentration (MIC) of Citrus aurantifolia lime peel ethanolic extract against P. acnes ATCC 6919 using the Kirby-Bauer disc diffusion method on Muller Hinton Agar (MHA). The extract was prepared by maceration with 96% ethanol from lime peels collected in Tulungagung, East Java, Indonesia. Fourteen concentrations (0.5–150 mg/mL) were tested in triplicate. The MIC was established at 1 mg/mL with an inhibition zone of 7.23 ± 0.15 mm. Inhibition zones increased proportionally with concentration, reaching 12.20 ± 0.10 mm at 150 mg/mL. Positive control (tetracycline 30 µg) produced 31.13 ± 0.38 mm. Antibacterial activity is attributed to multi-target mechanisms of flavonoids, tannins, alkaloids, and saponins acting on the cell wall, membrane, DNA, and virulence enzymes of P. acnes. These findings support the development of lime peel extract as a natural anti-acne ingredient.
Suppression of Staphylococcus epidermidis Skin Wound Infection by Citrus aurantifolia Lime Peel Ethanolic Extract: A Concentration-Response Analysis Putri, Amalia Eka; Santoso, Arif; Ginaris, Rifkarosita Putri
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 2 No. 01 (2023): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v2i03.56

Abstract

Staphylococcus epidermidis is a coagulase-negative Staphylococcus (CoNS) that causes a spectrum of superficial skin infections including wound infections, folliculitis, and burn-associated skin sepsis, particularly through its capacity to form highly resistant biofilms. The emergence of methicillin-resistant S. epidermidis (MRSE) with polysaccharide intercellular adhesin (PIA)-mediated biofilm has severely limited available therapeutic options. This study assessed the concentration-dependent bacteriostatic activity and minimum inhibitory concentration (MIC) of Citrus aurantifolia lime peel ethanolic extract against S. epidermidis ATCC 12228 using the Kirby-Bauer disc diffusion method on Muller Hinton Agar (MHA). Extract from lime peels sourced in Tulungagung, East Java was prepared by ethanol maceration. Fourteen concentrations (0.5–150 mg/mL) were tested in triplicate. The MIC was 1 mg/mL (inhibition zone 6.73 ± 0.06 mm). Inhibition zones increased progressively from 6.73 mm (MIC, 1 mg/mL) to 11.60 ± 0.35 mm (150 mg/mL), with the very strong threshold (>10 mm) first crossed at 70 mg/mL. Concentration-response linearity was confirmed (R² > 0.97). The positive control (tetracycline 30 µg) produced 28.17 ± 0.59 mm. These findings establish a pharmacological basis for incorporating lime peel extract into wound care and topical antiseptic formulations targeting S. epidermidis.
Minimum Inhibitory Concentration of Ethanol Extract of Vernonia amygdalina Delile. against Escherichia coli, Salmonella typhi, Staphylococcus aureus, and Bacillus cereus by Disc Diffusion Putri, Amalia Eka; Ginaris, Rifkarosita Putri; Indrayati, Lyna Lestari
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 4 No. 01 (2025): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v3i03.146

Abstract

Diarrhea remains a major global health challenge caused by pathogenic bacteria including Escherichia coli, Salmonella typhi, Staphylococcus aureus, and Bacillus cereus. African leaf (Vernonia amygdalina Delile.) contains bioactive compounds such as flavonoids, saponins, tannins, and alkaloids with recognized antibacterial properties. This study determined the Minimum Inhibitory Concentration (MIC) of ethanol extract of V. amygdalina prepared by Ultrasonic-Assisted Extraction (UAE) at three extraction times (5, 15, and 30 minutes) against four diarrhea-causing bacteria using the disc diffusion method. Extraction yields were 8.8%, 10.45%, and 11.9% for UAE at 5, 15, and 30 minutes, respectively. Antibacterial testing at concentrations ranging from 300 to 1.56 mg/mL demonstrated predominantly moderate inhibition zones (5–10 mm), with some concentrations reaching the strong category (10–20 mm). The MIC for B. cereus and S. aureus was 1.56 mg/mL across all extraction times. For S. typhi, the MIC was 1.56 mg/mL (5 and 30 min UAE) and 12.5 mg/mL (15 min UAE). For E. coli, the MIC was 6.25 mg/mL (5 min UAE) and 1.56 mg/mL (15 and 30 min UAE). One-way ANOVA confirmed statistically significant differences among concentrations (p < 0.05). The 30-minute UAE produced the highest yield and generally superior antibacterial activity, supporting its selection as the optimal extraction condition. These findings highlight the potential of V. amygdalina ethanol extract as a natural antibacterial agent for diarrheal disease management.
Co-Authors Andini, Mita Uly Andita, Jessica Shierly Arif Santoso Butarbutar, Glen Oloan Choirul Huda Danar Danar Danar, Danar Dyah Setyaningrum, Dyah Fadila, Natasya Nurul Ima, Ernisa Afidatul Jonathan, Brian Lyna Lestari Indrayati Muadifah, Afidatul Muadifah, Afidhatul Nana Dyah Siswati, Anwar Zain and Mohammad Nurcholis, Fachrul Nurin, Wachidatun Nurjanah, Mutia Hariani Rahma Diyan Martha Rahmawati, Desti Linda Dwi Rifkarosita Putri Ginaris Salsabila, Luqyana Sandi Mahesa Yudhantara Sari, Trianita Sowe, Momodou Salieu Sri Bintang Sahara Mahaputra Kusumanegara Sukma, Davit Dirgantara Suprihatin Suprihatin Tiara Aninditha Tilarso, Dara Pranidya Wimbuh Tri Widodo ‘Alimah, Erlisa Maratul