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Pengaruh Proporsi Tepung Sagu (Metroxylon sagu Rottb.) dan Tepung Sorgum (Sorghum bicolor L. Moench) terhadap Pati Resistan, Kandungan Gizi, dan Sifat Organoleptik Kukis untuk Diabetes Melitus Tipe 2: The Effect of Sago (Metroxylon sagu Rottb.) Flour and Sorghum (Sorghum bicolor L. Moench) Flour Proportion on Resistant Starch, Nutrient, and Organoleptic Properties of Cookies for Type 2 Diabetes Mellitus Lestari, Hana Tri; Fauziyah, A'immatul; Nasrulloh, Nanang
Amerta Nutrition Vol. 9 No. 1 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i1.2025.64-75

Abstract

Background: Basic Health Research (2018) reported that the prevalence of diabetes mellitus (DM) among individuals aged 15 years and older is 8.5%, with 90–95% of them being type 2 diabetes mellitus (DMT2). Therefore, corrective action through food modification is needed to control blood glucose. Sago and sorghum contain resistant starches that can enhance glycemic and insulin response. Objectives: To analyse the effect of the proportion of sago flour and sorghum flour on resistant starch, nutritional content, and organoleptic properties of cookies designated for T2DM. Methods: This study employed a Complete Randomised Design with 5 variations of sago flour and sorghum flour treatment, namely F1 (100%:0%), F2 (75%:25%), F3 (50%:50%), F4 (25%:75%), and F5 (0%:100%), each replicated twice. The analysis of resistant starch and nutritional content utilised a one-way ANOVA test, followed by the Duncan test for significant differences. Organoleptic properties were assessed using the Kruskal Wallis test. The best formulations were determined based on the De Garmo method. Results: The results revealed significant differences in resistant starch (p-value=0.002), protein (p-value<0.001), carbohydrate (p-value=0.012), and ash content (p-value=0.005). No significant differences were observed in fat (p-value=0.514), moisture content (p-value=0.881), colour (p-value=0.891), aroma (p-value=0.061), texture (p-value=0.164), and taste (p-value=0.421). The F2 formulation emerged as the best, containing 6.31% resistant starch, 7.34% protein, 23.69% fat, 50.95% carbohydrates, 16.19% moisture content, and 1.84% ash content. Conclusions: The proportion of sago flour and sorghum flour significantly affected the content of resistant starch, protein, carbohydrates, and ash content, but not fat, moisture content, and organoleptic properties.
Literature review dari randomized controlled trials (RCTs): Pengaruh prebiotik terhadap sistem kekebalan usus penderita diabetes mellitus tipe 2 Tiara Permatasari; A&#039;immatul Fauziyah
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3B (2024): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3B.1918

Abstract

Background: The gut microbiome, plays a crucial role in maintaining overall health. An imbalance in the microbiome (dysbiosis) can lead to various health issues, including type 2 diabetes. Prebiotics, as nutrients for gut microflora, have the potential to reduce dysbiosis and enhance gut immunity in type 2 diabetes patients. However, there is still limited research on the effects of prebiotics on gut immunity in individuals with type 2 diabetes.Objectives: To asses the effect of prebiotics on the gut immune system in patients with type 2 diabetes.Methods: A systematic literature review was conducted using the PRISMA method, including full-text RCT articles from 2014-2024. Databases searched included PubMed, Scopus, MDPI, and Elsevier.Results: Studies show prebiotics significantly influence gut microbiota composition, especially increasing Bifidobacterium in type 2 diabetes patients, though overall diversity remained unchanged due to short study durations.Conclusion: Prebiotics enhance gut microbiota, particularly Bifidobacterium, in type 2 diabetes patients. This increase, along with the production of SCFAs, plays a role in lowering gut pH, supporting the growth of beneficial bacteria, and inhibiting pathogens. These findings suggest the potential of prebiotics as part of type 2 diabetes management; however, further research is needed to confirm their clinical application. Healthcare institutions are encouraged to develop educational programs emphasizing the importance of gut microbiota and the role of prebiotics in the health of type 2 diabetes patients.
Literatur Review RCTs: Pengaruh probiotik terhadap sistem kekebalan tubuh pada pasien penyakit infeksi saluran pernapasan Dhiya Agis Ghazalah; A&#039;immatul Fauziyah
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3B (2024): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3B.1916

Abstract

Background: Probiotics are bacteria that can be immunomodulators and interact with the body's immune system. There is a lack of information regarding the relationship between probiotics and the immune system in individuals who experience illness, especially respiratory infections.Objectives: This article complements the current information contained in several journals about the relationship between probiotics and the immune system in patients with respiratory tract infections.Methods: This descriptive study used a systematic literature review method and was conducted from February to May 2024. Literature from publication years 2014–2024 was obtained from PubMed, Google Scholar, Research Gate, and ScienceDirect. Data collection and analysis used the Preferred Reporting Items for Systematic Reviews (PRISMA) guidelines. A total of 71 articles were collected and selected in stages based on predetermined inclusion criteria. Four articles were successfully selected and then analyzed to find similarities, differences, and perspectives. The data was presented in the form of an extraction table for the population of all age ranges who experienced respiratory infectious diseases. The samples taken were those experiencing respiratory infectious diseases and taking probiotics.Results: Probiotics affect the immune system in patients with respiratory infections by increasing the size and number of plasma cells that produce immunoglobulin-A (IgA) and T cells..Conclusion: Probiotics affect the immune system of infectious disease patients by modulating the innate immune system as well as their antiviral properties. This is in line with previous research information where probiotics are effective in reducing the effects of respiratory infections and improving the immune system.KeywordsRespiratory Infectious Diseases, Probiotics, and the Immune System
Tinjauan sistematis: Korelasi vitamin D terhadap Sel T regulator pada penderita lupus eritematosus sistemik Sherly Permata; Aimmatul Fauziyah
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3B (2024): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3B.1922

Abstract

Background: Vitamin D is linked to immunity and autoimmune diseases, including systemic lupus erythematosus (SLE). Autoimmune diseases often involve impaired regulation of regulatory T cells (Tregs). Despite numerous studies exploring the relationship between vitamin D and Tregs in SLE, the findings remain inconclusive.Objectives: To determine whether there is a relationship or correlation between vitamin D and regulatory T cells in patients with systemic lupus erythematosus based on existing research articles employing different research methods.Methods: We conducted a systematic literature review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines from February to May 2024. We sourced articles from Google Scholar, PubMed, and MDPI, focusing on research published between 2014 and 2024. Inclusion criteria were relevance to the topic and availability in full text, while exclusions were animal studies, research older than ten years, and articles not available in full text. Seven articles met the criteria and were reviewed.Results: Out of the seven articles reviewed, five found a correlation between vitamin D levels and the ratio and function of Tregs in SLE patients. Specifically, higher levels of vitamin D were associated with increased suppression of Tregs.Conclusion: The results of studies on vitamin D levels and Tregs in SLE patients are inconsistent. Further evaluation and additional research are required to determine the potential clinical benefits of vitamin D management in SLE therapy. 
Low Sun Exposure as a Dominant Risk Factor of Hypertension Among Adolescents in SMPN 21 South Tangerang Novita Harumsari; Firlia Ayu Arini; Aimmatul Fauziyah; Utami Wahyuningsih
Jurnal Ilmu Kesehatan Masyarakat Vol. 14 No. 2 (2023): Jurnal Ilmu Kesehatan Masyarakat (JIKM)
Publisher : Faculty of Public Health, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26553/jikm.2023.14.2.223-238

Abstract

Hypertension is a global health problem that can occur in adolescents. According to Riskesdas 2018, the national prevalence of hypertension is 34.1%. In Banten Province, it stands at 29.4%, and in South Tangerang City, it’s 27.5%. This study was aimed to determine the association between age, sex, vitamin D intake, fat intake, and sun exposure with the incidence of hypertension among adolescents at SMPN 21 South Tangerang and the dominant factor among these variables that is a risk factor of hypertension. This study used a cross-sectional design with a sample of 102 respondents taken using a stratified random sampling technique. Data were collected through blood pressure measurements, the Sun Exposure Questionnaire (SEQ), and the Semi Quantitative Food Frequency Questionnaire (SQ-FFQ). Association analysis was conducted using the chi-square test and Fisher's exact test, showing that there was an association between sun exposure (<0.05; OR = 7.902) with the incidence of hypertension, and there were no association between age (p = 0.556), sex (p = 0.386), vitamin D intake (p = 0.760), and fat intake (p = 1.000) with the incidence of hypertension among adolescents at SMPN 21 South Tangerang. The result of multivariate analysis using the regression logistic test showed that sun exposure was the most correlated factor of hypertension among adolescents at SMPN 21 South Tangerang (p = <0.05; OR = 7.949). Respondents should have more sun exposure to prevent hypertension.