Fibryanto, Eko
Departemen Konservasi Gigi, Fakultas Kedokteran Gigi, Universitas Trisakti, Jakarta, Indonesia

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Journal : Odonto dental journal

THE EFFECT OF 17% ETHYLENEDIAMINETETRA-ACETIC ACID AS A MAIN IRRIGATION ON APICAL ROOT CANAL CLEANLINESS (ex vivo) Eko Fibryanto
Odonto : Dental Journal Vol 7, No 2 (2020): December 2020
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (908.105 KB) | DOI: 10.30659/odj.7.2.117-124

Abstract

Background: The root canal wall becomes coated with a smear layer predominantly composed of organic and inorganic matter, debris and bacteria during root canal instrumentation. Sodium hypochlorite (NaOCl) and ethylenediaminetetra-acetic acid (EDTA) are effective in removing the smear layer and they perform as lubricants during root canals instrumentation. The aim of this study was to analyze the efficacy of NaOCl and EDTA as lubricant during root canal preparation on apical third of root-canal wall.Method: Thirty-two premolars were all decoronated. All samples were randomly divided into 2 groups. All groups were instrumented with rotary instrument from #10.04 to #35.04 file. One group was irrigated with 17% EDTA and the other with 5.25% NaOCl. Then the teeth were dried, split into 2 halves and evaluated by 2 examiners under scanning electron microscopy (SEM) at the apical third of the root-canal wall at 1000x magnifications. Data was statistically analyzed using Mann-Whitney test.Result: The result showed that 17% EDTA produced significantly higher cleanliness on apical third of root-canal wall compared to 5.25% NaOCl (p < 0.05).Conclusion: EDTA 17% was able to clean apical third of root-canal wall better than NaOCl 5,25%.
pH And Antibiofilm Analysis Of Elephant Ginger (Zingiber Officinale Var. Officinale) Mouthwash Formulations Against Streptococcus Mutans – An In Vitro Study Fibryanto, Eko; Stefani, Rosita; Santoso, Lidia
Odonto : Dental Journal Vol 12, No 1 (2025): April 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.1.7-18

Abstract

Background: Caries is the most common oral disease. Streptococcus mutans is the main microorganism in caries etiology due to its ability to form biofilm. Biofilm can be eliminated using mouthwash. Elephant ginger (Zingiber officinale var. officinale) can be developed as a herbal mouthwash because it is able to inhibit S. mutans. This study aimed to analyze pH and antibiofilm effect in vitro of elephant ginger mouthwash formulations on S. mutans. Method: Elephant ginger was macerated with 96% ethanol, then formulated into 2.5%, 5%, 10%, and 15% mouthwash formulations, underwent pH measurement for 28 days, and their antibiofilm effect on S. mutans were measured using microplate reader for 1h (therapeutic assay) and 24h (preventive assay). Result: All formulations showed pH values ranging from 6.42-6.87, changing significantly within 28 days. All formulations were able to reduce S. mutans biofilm adherence for 1h better than commercialized herbal mouthwash and similar to 0.1% CHX. Furthermore, 5% and 10% mouthwash formulations showed similar effectivity to 0.1% CHX and commercialized herbal mouthwash in inhibiting S. mutans biofilm formation for 24h, while 15% mouthwash formulation was more effective than 0.1% CHX and similar to commercialized herbal mouthwash, and 2.5% mouthwash formulation was less effective than 0.1% CHX and commercialized herbal mouthwash. Conclusion: Elephant ginger mouthwash formulations showed pH values that were likely to decrease for 28 days and had the potential as an herbal mouthwash due to its antibiofilm effect on S. mutans.