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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Media Dermato-Venereologica Indonesiana
Regitta Indira Agusni
Department Of Dermatology And Venereology, Faculty Of Medicine Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, Surabaya
Health Professions Immunology & microbiology Public Health

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Diagnosis and Management of Leprosy Medhi Denisa Alinda; Silvani Geani; Regitta Indira Agusni; Bagus Haryo Kusumaputra; Novianti Rizky Reza; Cita Rosita Sigit Prakoeswa; Muhammad Yulianto Listiawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 2 (2020): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.2.2020.149-157

Abstract

Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which tends to attack peripheral nerves and skin. The diagnosis of leprosy is based on the presence of one of three cardinal signs. Early diagnosis of leprosy is critical and is made through clinical examination and investigation. Purpose: To discuss the diagnosis, laboratory examination, and treatment of leprosy, considering that early diagnosis and appropriate treatment are the key elements in breaking the chain of transmission and preventing leprosy patients' disabilities. Review: Leprosy is a chronic granulomatous infectious disease caused by the Mycobacterium leprae. Based on clinical appearance, histopathology findings, and immunological, leprosy is grouped into six forms using the Ridley-Jopling classification, namely Tuberculoid (TT), Borderline Tuberculoid (BT), Borderline-borderline Mid-borderline (BB), Borderline-lepromatous (BL), Subpolar Lepromatous (LLs), and Polar Lepromatous (LLp). Based on the treatment category, leprosy is grouped into paucibacillary (PB) and multibacillary (MB). Leprosy is often diagnosed clinically, and skin scraping smear remains the preferred laboratory method. The negative results of smear skin scraping may not necessarily exclude leprosy. Therefore, a higher sensitivity test might be needed to detect M. leprae. Treatment with Multi-Drug Therapy (MDT) is adjusted based on the type of leprosy, whether it belongs to the PB or MB group. Treatment of PB type, regimens are rifampicin and dapsone, while in MB type, the patients received rifampicin, dapsone, and clofazimine regimens. Conclusion: A proper diagnosis for leprosy, both through physical examination and laboratory examination, is required to determine an effective MDT treatment and break the chain of disease transmission.
The Effectiveness of 5% Tea Tree Oil cream, 10% Tea Tree Oil cream, and 5% Permethrin Cream for Scabies Treatment in Pediatric Patients Chesia Christiani Liuwan; Muhammad Yulianto Listiawan; Dwi Murtiastutik; Evy Ervianti; Sawitri Sawitri; Cita Rosita Sigit Prakoeswa; Linda Astari; Farhat Surya Ningrat; Kurniati Kurniati; Endang Wahyu Fitriani; Irmadita Citrashanty; Regitta Indira Agusni; Iskandar Zulkarnain
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 3 (2020): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.3.2020.200-205

Abstract

Background: Scabies, an infectious disease caused by Sarcoptes scabiei mites, is still one of the most common skin diseases found in developing countries, including Indonesia. The 5% permethrin cream for scabies treatment has been investigated as having 2–3 time to cure scabies. Tea Tree Oil (TTO) is one of the agents that has been proven to have acaricidal potential as an anti-inflammatory, antibacterial, and antipruritic agent. It has minimal side effects in topical use. Purpose: To evaluate the effectiveness of 5% TTO cream and 10% TTO cream in scabies treatment of pediatric patients. Methods: This was an experimental, analytical study with controlled clinical trial methods, and a double-blind, parallel design comparing 5% TTO cream (treatment 1), 10% TTO cream (treatment 2), with 5% permethrin cream (control) to children with scabies. Result: The 5% TTO cream gave a cure rate of 61.5% and was significantly different from the 5% permethrin cream groups with a p-value = 0.044 in the first week of the study. The 5% permethrin cream gave a cure rate of 15.4%, and the cure rate of 10% TTO cream was 53.8% in the first week of the study. Conclusion: There was a significant difference between the 5% TTO cream and 5% permethrin cream in the first week of the study. The highest and fastest cure rates were found in the 5% TTO cream treatment group.
Epidemiology of Leprosy in Indonesia: a Retrospective Study Lubis, Ramona Sari; Anum, Qaira; Argentina, Fifa; Menaldi, Sri Linuwih; Gunawan, Hendra; Yuniati, Renni; Mulianto, Nur Rachmat; Siswati, Agnes Sri; Widasmara, Dhelya; Rusyati, Luh Made Mas; Mamuaja, Enricco Hendra; Muchtar, Vitayani; Cita Rosita Sigit Prakoeswa; Agusni, Regitta Indira; Bagus Haryo Kusumaputra; Medhi Denisa Alinda; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.29-35

Abstract

Background: According to WHO data, the number of new cases of leprosy has decreased in 2019. However, Indonesia continues to provide a significant number of cases. According to statistics, India, Brazil, and Indonesia account for 79 percent of all instances. Purpose: This study aims to describe the profile of leprosy patients, and involves all Dermatology and Venereology Academic Hospitals in Indonesia. Methods: This study was a retrospective study of 2461 patients from Dermatology and Venereology Outpatient Clinic at 13 Academic Hospitals in Indonesia between January 2018 and December 2020. Result: Subjects in this study were dominated by males (66.8%) and aged > 14 years (95.3%). The most common type of leprosy was multibacillary (MB) (86.2%), and erythema nodosum leprosum (ENL) was the most leprosy reaction (20.3%). Majority of the subjects experienced disability in the hands (26.6%), in grade 1. Conclusion: Leprosy cases in Indonesia are mostly experienced by adult males. The most common type of leprosy is MB, with ENL being the most common leprosy reaction. Grade 1 disability is the most prevalent, therefore proper education is necessary to keep patients from progressing to grade 2 disability.
Sexually Transmitted Infections among Human Immunodeficiency Virus Patients in a Tertiary Hospital in Surabaya, Indonesia Suryanegara, Jose; Pilar, Nissa Avina; Riswanto, Cintya Dipta; Agusni, Regitta Indira; Sari, Maylita; Astindari; Widyantari, Septiana; Nurul Hidayati, Afif; Murtiastutik, Dwi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 2 (2025): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.2.2025.119-124

Abstract

Background: Human immunodeficiency virus (HIV) remains a significant global public health concern. One of its primary modes of transmission is sexual contact, leading to frequent co-infection with other sexually transmitted infections (STIs). Understanding the profile of STIs among HIV patients is essential for improving management and prevention strategies. Purpose: This study aims to describe the prevalence, types, and basic demographic characteristics (age and sex) of STIs among HIV patients treated at a tertiary referral hospital in Indonesia, to enhance understanding and optimize patient care. Methods: A retrospective observational study was conducted at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Researchers analyzed the medical records of HIV patients who had coexisting STIs and visited the dermatology and venereology outpatient clinic between January 2021 and December 2022. Data collected included patient demographics, STI diagnoses, and clinical characteristics. Result: A total of 222 HIV patients with STIs were included, with a male predominance (85.6%) and a mean age of 28.64 years. The most common STIs were anogenital warts (47.7%), latent syphilis (18.0%), unspecified syphilis (10.8%), secondary syphilis (10.4%), and molluscum contagiosum (7.7%). The findings highlight the variations in STI prevalence based on sex and age distribution among HIV patients. Conclusion: This study points out that there are integrated management and prevention strategies targeting both HIV and STIs. Although our study did not specifically assess sexual orientation, previous research highlights men who have sex with men (MSM) as a key high-risk population.
PERKEMBANGAN GLOBAL PENELITIAN DERMATOLOGI ANAK DALAM DUA DEKADE TERAKHIR: Perkembangan Global Penelitian Dermatologi Anak Kinanti, Hapsari; Agusni, Regitta Indira; Nurasrifah, Dewi; Widia, Yuri; Reza, Novianti Rizky; Alinda, Medhi Denisa; Damayanti, Damayanti; Hidayati, Afif Nurul
Media Dermato-Venereologica Indonesiana Vol 52 No 3 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i3.456

Abstract

Pendahuluan: Penelitian di bidang dermatologi anak terus berkembang sejak tahun 1986. Jumlah penelitian yang terus meningkat menimbulkan tantangan bagi tenaga kesehatan dalam mengikuti dan memahami seluruh perkembangan ilmu pengetahuan. Penelitian ini bertujuan menyajikan perkembangan terkini dalam bidang dermatologi anak yang dapat digunakan sebagai dasar untuk menentukan arah penelitian lebih lanjut. Metode: Kajian bibliometrik menggunakan data dari Scopus dianalisis menggunakan Biblioshiny dan VOSviewer untuk memberikan gambaran mengenai produktivitas dan tren topik penelitian. Hasil: Dalam dua dekade terakhir, terdapat peningkatan jumlah produksi artikel mengenai dermatologi anak setiap tahunnya. Negara yang paling produktif menghasilkan artikel didominasi oleh negara maju. Dua topik yang paling banyak diteliti adalah dermatitis atopik dan psoriasis, aspek keamanan terapi biologis, dan terapi target agar dapat digunakan pada populasi anak sedini mungkin. Penanganan hemangioma infantil dan erupsi obat pada anak menggunakan agen sistemik dan biologis sedang gencar diteliti pada dekade terakhir. Teledermatologi dan artificial intelligence menjadi gambaran pelayanan dermatologi anak di masa yang akan datang. Hal ini menunjukkan bahwa penelitian di bidang dermatologi anak masih terus berkembang. Kesimpulan: Diperlukan kolaborasi antara peneliti di negara berkembang dan negara maju untuk memperluas subjek penelitian dan menciptakan hasil penelitian dengan dampak yang lebih besar. 
Co-Authors Afif Nurul Hidayati, Afif Nurul Agnes Sri Siswati Anum, Qaira Astindari Bagus Haryo Kusumaputra Bagus Haryo Kusumaputra Chesia Christiani Liuwan Cita Rosita Sigit Prakoeswa Damayanti Damayanti Dhelya Widasmara Dwi Murtiastutik Endang Wahyu Fitriani Evy Ervianti Farhat Surya Ningrat Fifa Argentina Irmadita Citrashanty Iskandar Zulkarnain Jayawarsa, A.A. Ketut Kinanti, Hapsari Kurniati Kurniati Linda Astari, Linda Lubis, Ramona Sari Luh Made Mas Rusyati M. Yulianto Listiawan Mamuaja, Enricco Hendra Maylita Sari, Maylita Medhi Denisa Alinda, Medhi Denisa Muchtar, Vitayani Mulianto, Nur Rachmat Novianti Rizky Reza Nurasrifah, Dewi Nurul Hidayati, Afif Pilar, Nissa Avina Renni Yuniati Reza, Novianti Rizky Riswanto, Cintya Dipta Sawitri Sawitri Silvani Geani Sri L. Menaldi Suryanegara, Jose Widyantari, Septiana Yuri Widia, Yuri