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All Journal Indonesian Journal of Tropical and Infectious Disease Science and Technology Indonesia Jurnal Biologi Tropis Jurnal Abadimas Adi Buana Cendana Medical Journal Jurnal Veteriner Nusantara Jurnal Pengabdian Masyarakat dan Riset Pendidikan JURNAL FLOBAMORATA MENGABDI
Audrey Gracelia Riwu
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Veterinary Other

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Journal : Science and Technology Indonesia

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Determination of (+)-Catechin and Antioxidant Activity in Faloak (Sterculia quadrifida R. Br) Stem Bark Infusion Audrey Gracelia Riwu; Jusak Nugraha; Djoko Agus Purwanto; Erwin Astha Triyono
Science and Technology Indonesia Vol. 8 No. 1 (2023): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2023.8.1.59-65

Abstract

Oxidative stress is a condition that can damage human cells and tissues and has been linked to a number of illnesses, including cancer, cardiovascular disease, autoimmune disorders, and neurological diseases. Oxidative stress conditions can be brought on by pollution, radiation exposure, and an unhealthy lifestyle. Antioxidants are substances that can be used to both prevent and treat oxidative stress. This study aimed to identify and quantify (+)-catechin levels and antioxidant activity of the stem bark of Sterculia quadrifida R. Br extracted by the infusion method, a method similar to traditional medicine processing generally in the community. Determination of (+)-catechin and antioxidant activity of S. quadrifida were evaluated by HPLC and DPPH assay, respectively. Quantification of (+) catechin content by HPLC system with wavelength 280 nm and antioxidant activity by spectrophotometry method with wavelength 517 nm. The results show that the mean value of (+)-catechin level was 7.786% and the IC50 value of the antioxidant activity was 51.5 ug/mL having a moderate antioxidant activity category. S. quadrifida stem bark infusion can be utilized as a medication candidate for the prevention or treatment of a variety of disorders caused by oxidative stress.
Co-Authors Asa, Halena Meldy Djoko Agus Purwanto Dwita Anastasia Deo Erwin Astha Triyono Jannah, Insani Fitrahulil Jusak Nugraha Kale, Maria Laurenci Fanny Permata Kale, Maria Laurenci Fany Permata Koamesah, Sanggwana Marthen Jacobus Kolobani, Mathias Nathaniel Loe, Fhady Rischky Loe, Fhady Risckhy Muhajirin Dean Nugaraha, Jusak Nurul Azizah Nurul Azizah Nurul Azizah Nurul Fatmawati Pua Upa Pandango, Dominggus R.K.U.W Pua Upa, Nurul Fatmawati Purnasari, Cahyani Rante, Su Djie To Rini, Desi Indria Riwu, Katty Hendriana Priscilia Simarmata, Yohanes TRMR Syahrir Syahrir Tenis, Linus Chaesarandy Tunggal, Deif Upa, Nurul Fatmawati Pua Wardani, Nimas Prita Rahajeningtyas Kusuma Woda, Rahel Rara Wuhan, Yustinus Oswin Primajuni Yoes Prijatna Dachlan