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Comparison Of Polyphenol Antioxidant Levels In Fig Plant Leaves, Skin, And Flesh Using The DPPH Method Annisa Ancha; Rachmat Faisal Syamsu; Iin Widya Ningsi; Armanto Makmun; Andi Millaty Halifah Dirgahayu Lantara
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

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Abstract

Fig plants (Ficus carica) are known to have potential as a source of antioxidants, especially from the polyphenol content found in the leaves, skin, and fruit flesh. This study aims to compare the antioxidant activity of polyphenols in three parts of the fig plant using the DPPH (2,2-diphenyl-1-picrylhydrazyl) test method to measure free radical inhibition. Extraction was carried out using 96% ethanol, and antioxidant activity was tested at concentrations of less than 100 ppm. The results showed that fig leaves had the highest antioxidant activity with an inhibition percentage of 75.991%, followed by fig flesh at 56.559%, and fig skin at 48.925%. ANOVA test analysis showed significant differences between the three parts of the plant with a significance value of p of 0.004 (<0.05), which confirmed that fig leaves have higher antioxidant potential than the skin and fruit flesh. This study provides useful information for the development of fig-based health products.
The Effect Of Atypical Antipsychotic Administration On Weight Changes In Patients With Mood Disorders At Dadi Regional Special Hospital, South Sulawesi Province Lianda Gustisa; Rachmat Faisal Syamsu; Ilma Khaerina Amaliyah; Muh.Alim Jaya; Muh.Wirasto
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

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Abstract

Antipsychotic medications are often used to treat mood disorders. Atypical antipsychotics are currently the first-line treatment for patients with mood disorders. However, they can have side effects, significant metabolic side effects, such as central adiposity and weight gain. This study was conducted with the aim of analyzing the Effect of Atypical Antipsychotic Administration on Weight Change in Mood Disorder Patients at the Dadi Regional Special Hospital, South Sulawesi Province. Using descriptive research design with cross sectional method, with a sample of 27 informants. The results of the study. The results showed a significant difference between body weight before and after treatment, the provision of atypical antipsychotic therapy for 1 month showed significant changes in weight measurements of patients with mood disorders on average 0.5 kg - 2 kg. Giving atypical antipsychotic therapy for 2 months showed significant changes in weight measurements of patients with mood disorders on average 2 kg - 5 kg.
Effect of Bandotan (Ageratum conyzoides Linn) leaf extract and wild honey provision on cut wound healing in mice Vivi Chairun Nisa; Syamsu Rijal; Marzelina Karim; Rachmat Faisal Syamsu; Dzul Ikram
International Journal of Health Science and Technology Vol. 6 No. 3 (2025): April
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v6i3.3963

Abstract

Cuts are a common form of injury caused by trauma from sharp objects such as knives, razor blades, or other sharp objects. In Indonesia, traditional wound treatment is still widely used, one of which is by using Bandotan leaves (Ageratum conyzoides Linn), which is known to have the ability to stop bleeding and accelerate wound healing. In addition, wild honey from Apis dorsata bees also contains various active compounds that can be significant for the wound healing process. Data from Riskesdas (Riset Kesehatan Dasar - Basic Health Research) showed that the prevalence of cut/slash/stab wound cases in South Sulawesi in 2018 reached 27.76%, so an effective and natural alternative treatment is needed. This study aims to determine the content of phytochemical compounds in Bandotan leaf extract and wild honey; and compare their effectiveness on cut healing in mice (Mus musculus), both macroscopically and histologically. This study employed a quantitative experimental method with a Pretest-Posttest Control Group Design. The results show that Bandotan leaf extract contains alkaloids, flavonoids, steroids, and saponins; while wild honey contains flavonoids and saponins. Macroscopically, wild honey is more effective in accelerating wound healing than the other groups. However, microscopically, the Bandotan leaf group shows higher epidermal thickness. Complete re-epithelialization occurs in all groups, while keratinization does not only occur in the negative control group. In conclusion, wild honey is more clinically effective in accelerating wound healing, while Bandotan leaves show potential for tissue regeneration based on histology.
Penanganan dan Preventif Sindrom Stevens Johnson di Masyarakat Hermiaty; Rachmat Faisal Syamsu; Nur Akhsan Diana
Cerdika: Jurnal Ilmiah Indonesia Vol. 1 No. 5 (2021): CERDIKA: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v1i5.80

Abstract

Abstrak: AbsSindrom Stevens-Johnson (SSJ) merupakan sindrom yang mengenai kulit, selaput lendir di orifisium, dan mata dengan keadaan umum yang bervariasi dari ringan hingga berat. SSJ merupakan bentuk minor dari toxic epidermal necrolysis (TEN) dengan pengelupasan kulit kurang dari 10% luas permukaan tubuh. Penyakit ini bersifat akut dan pada bentuk yang berat dapat menyebabkan kematian, oleh karena itu penyakit ini merupakan salah satu kegawat daruratan dari penyakit kulit. Etiologi SSJ dan NET digolongkan menjadi empat kategori, antara lain infeksi, obat, berhubungan dengan keganasan, serta idiopatik, namun penyebab utama adalah paparan obat.Di Indonesia obat yang diperkirakan paling sering menyebabkan SJS adalah antipiretik dan analgetik.Penanganan utama pada SSJ-NET adalah dengan menghentikan penggunaan obat yang dicurigai sebagai penyebab. Terapi lain yang dapat diberikan masih kontroversial, seperti pemberian kortikosteroid, IVIG, plasmaferesis dan cyclosporine.