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OPTIMASI EFEK ANALGETIK SIRUP EKSTRAK DAUN BELUNTAS (Pluchea Indica (L.) Less.) TERHADAP MENCIT JANTAN PUTIH (Mus Musculus) DENGAN METODE RANGSANG PANAS Listina, Osie
Usadha Vol 1 No 2 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Beluntas plants generally grow wild in dry areas and have enormous benefits in treatment such as eliminating body odor, increasing appetite, overcoming pain and reducing fever. Beluntas leaves contain flavonoids which help the process of relieving pain. Pain is an uncomfortable sensory and emotional feeling related to (threatening) tissue damage. This study aimed to determine whether there is an analgesic effect of beluntas leaves extract syrup. This study was experimental using 25 mice which were divided into 5 groups. The negative control group was given aquades, positive control group was given paracetamol, and 3 experimental groups were given beluntas leaves extract syrup, each with a dose of 150mg/kgBB, 300 mg/kgBB, and 600mg/kgBB. Testting of analgesic effect was conducted by giving pain to test animals, in the form of hot stimulus with temperature of 550C. The response of the mice observed was the licking of the feet and or jumping. Observations were made for 1 minute. Observations were made before giving the test substance, and then successively in the 30, 60, 90, and 120 minutes after administration of the test substance. The results showed the number of responses to pain stimuli in the group of mice given beluntas leaves extract syrup began to decline in the 30 minute and continued to give effect in the 60 minute. In the 90th minute the analgesic effect began to decline, but it still showed the analgesic effect.At the second and third concentrations (300mg/kgBW : 600mg/kgBW) syrup of beluntas leaf extract (Pluchea indica (L.) Less.) had the best analgesic effect.
Efektivitas Antibakteri Sediaan Susu Pembersih(Milk cleanser) Ekstrak Ranting Tanaman Patah Tulang (Euphorbia tirucalli) terhadap Propionibacterium acne Qomah, Isti; Rejeki, Desi Sri; Listina, Osie
KUNIR: JURNAL FARMASI INDONESIA Vol 2 No 1 (2024): JULI
Publisher : Program Studi Farmasi (S-1), Fakultas Ilmu Kesehatan, Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/kjfi.v2i1.590

Abstract

Ranting tanaman patah tulang (Euphorbia tirucalli) dapat dimanfaatkan sebagai antibakteri. Kandungan metabolit sekunder yang dimiliki ranting patah tulang meliputi flavonoid, steroid, dan tannin. Penelitian ini bertujuan untuk memformulasikan sediaan milk cleanser dengan ekstrak etanol ranting tanaman patah tulang dan menguji aktivitas antibakteri dengan konsentrasi 5,10, dan 15% terhadap pertumbuhan Propionibacterium acne. Metode penelitian aktivitas bakteri terhadap Propionibacterium acne dilakukan dengan metode sumuran. Hasil penelitian ranting tanaman patah tulang mengandung senyawa saponin, tannin, alkaloid dan flavonoid. Ekstrak memenuhi kadar air 4,5% dan kadar abu total 0,15%. Hasil aktivitas antibakteri milk cleanser ekstrak ranting tanaman patah tulang mampu menghambat pertumbuhan Propionibacterium acne dengan konsentrasi F1(5%) daya hambat sedang, konsentrasi F2 (10%) daya hambat kuat dan konsentrasi F3 (15%) daya hambat sangat kuat. Berdasarkan uji One Way Anova pada ekstrak ranting tanaman patah tulang memiliki nilai signifikansi 0,000 dimana nilai F hitung > F tabel atau 216,706 > 4,07. Sedangkan pada uji sediaan milk cleanser memiliki nilai signifikansi 0,000 dimana nilai F hitung > F tabel atau 568,300 > 4,07. Sehingga hipotesis diterima yang berarti ada pengaruh perbedaan daya hambat milk cleanser ekstrak ranting tanaman patah tulang.
PENGENALAN APOTEKER CILIK PADA SISWA SD SEKOLAH ALAN ANANDA MANDIRI KABUPATEN TEGAL Fahamsya, Arifina; Listina, Osie; Garna, Lailiana; Nida, Shofa Khoirun; Musrifah, Musrifah; Fahamsya, Arini
JABI: Jurnal Abdimas Bhakti Indonesia Vol 5 No 1 (2024): Juni
Publisher : UNIVERSITAS BHAMADA SLAWI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/jabi.v5i1.644

Abstract

Pengenalan Apoteker sebagai salah satu profesi di bidang kesehatan yang memiliki keahlian pada obat dan informasi obat, namun masyarakat banyak yang belum mengetahui profesi tersebut. Pengabdian dilakukan dengan metode sosialisasi dan edukasi beserta dengan alat peraga kepada siswa kelas 3 dan 4 SD Sekolah Alam Ananda Mandiri. Materi yang disampaikan berupa materi pengenalan profesi apoteker dan pengenalan bentuk sediaan obat. Kegiatan ini bertujuan untuk memperkenalkan profesi apoteker dan memastikan obat-obatan diminum dengan benar sehingga dapat menangani penyakit dengan baik dan meningkatkan kualitas hidup. Hasil pengabdian menunjukkan bahwa siswa sangat antusias dan aktif dalam mengikuti kegiatan ini sehingga terjadi perubahan pengetahuan siswa terkait profesi apoteker dan penggunaan obat. Edukasi seperti ini perlu dilakukan peningkatan dengan jumlah peserta yang lebih banyak dari berbagai macam sekolah sehingga akan memberikan dampak positif semakin banyak siswa tingkat sekolah dasar mengetahui cara penggunaan obat dengan tepat.
PENDAMPINGAN KADER PPKBD DAN KELOMPOK MASA PRAKONSEPSI DESA SURAJAYA KECAMATAN PEMALANG MEWUJUDKAN GENERASI BEBAS STUNTING Listina, Osie; Cahyanta, Agung Nur; Oktiawati, Anisa; Ayundari, Sukma Marifat; Azam, Rizki Restiana
JABI: Jurnal Abdimas Bhakti Indonesia Vol 5 No 2 (2024): Desember
Publisher : UNIVERSITAS BHAMADA SLAWI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/jabi.v5i2.738

Abstract

Permasalahan utama mitra adalah bagaimana bentuk pendampingan Kader PPKBD (Pembantu Pembina Keluarga Berencana Desa) terkait upaya percepatan penurunan angka stunting dan bagaimana cara memberikan edukasi dan konseling kepada kelompok masa prakonsepsi di Desa Surajaya dalam menyiapkan kehamilan yang sehat untuk mencegah stunting. Tujuan kegiatan ini adalah melakukan pendampingan Kader PPKBD terkait upaya percepatan penurunan angka stunting khususnya di Desa Surajaya dengan mengolah dan memproduksi, makanan tambahan yang kaya gizi untuk balita stunting dan memberikan edukasi serta konseling dengan melakukan “Kampanye Keluarga Hebat” kepada kelompok masa prakonsepsi atau remaja calon pengantin. Metode yang dilakukan dengan lima tahapan kegiatan yaitu sosialisasi, pelatihan, penerapan teknologi (pelatihan dan edukasi), pendampingan dan evaluasi kegiatan, serta keberlanjutan program. Hasil analisis data diperoleh bahwa konsep stunting vs faktor risiko melahirkan anak stunting memiliki sig 0.000 (artinya kurang dari 0,05) menandakan bahwa ada hubungan antara pengetahuan terkait stunting dengan pengetahuan responden terhadap pertanyaan terkait konsep stunting, faktor risiko melahirkan anak stunting, perencanaan kehamilan, dan sanitasi dan higienitasi setelah dilakukan penyuluhan.
FORMULASI SEDIAAN BODY SCRUB KOMBINASI EKSTRAK KULIT JERUK BALI (Citrus maxima Merr.) DENGAN CANGKANG TELUR AYAM SEBAGAI AGEN EKSFOLIASI Aisy, Syifa Rihadatul; Alfiraza, Ery Nourika; Listina, Osie
Usadha Journal of Pharmacy Vol. 3 No. 3 (2024): Agustus
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v3i3.394

Abstract

Body scrub adalah salah satu produk kosmetik dengan bahan agak kasar yang digunakan untuk merawat, membersihkan kotoran kulit, dan mengangkat sel kulit mati. Penelitian ini bertujuan untuk mengetahui karakteristik uji stabilitas fisik body scrub kombinasi ekstrak kulit jeruk bali (Citrus maxima Merr.) dengan cangkang telur ayam serta mengetahui sediaan tersebut tidak mengiritasi kulit. Body scrub dibuat empat formulasi yang meliputi F0 (tanpa ekstrak), FI (ekstrak 15%), FII (ekstrak 12,5%) dan FIII (ekstrak 10%). Hasil dari penelitian uji fisik menunjukan bahwa uji organoleptis, uji pH, uji homogenitas, uji daya sebar dan uji daya lekat memenuhi syarat, sedangkan pada uji tipe emulsi F0 menunjukan A/M (air dalam minyak) dan pada FI, FII dan FIII menunjukan M/A (minyak dalam air). Kemudian hasil dari uji stabilitas menggunakan metode cycling test F0, FI, FII dan FIII tidak menunjukan adanya pemisahan antara fase minyak dan fase air serta pH stabil selama 6 siklus. Setelah dilakukan uji iritasi hasil dari F0, FI, FII dan FIII tidak menimbulkan iritasi sehingga sediaan aman digunakan pada kulit manusia. Data yang diperoleh dianalisis dengan menggunakan One Way Anova pada program SPSS 29.
Analisis Keputusan Pemilihan Penggunaan Obat Herbal dan Obat Konvensional di Kalangan Usia Produktif Kecamatan Pangkah Khoirunnisa, Dhea Ayu; Listina, Osie; Alfiraza, Ery Nourika
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 1 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i1.5350

Abstract

Herbal medicine and conventional medicine are two primary treatment options commonly used by the productive age population in addressing health issues. This study aims to determine the percentage of medicine preference, the dominant factors influencing decision-making, as well as the knowledge of medicinal plants and attitudes of the productive age community toward the use of herbal and conventional medicines. The research employed a mixed-methods using questionnaires and interviews through stratified random sampling. The results showed that 61% of respondents preferred conventional medicine, while 39% chose herbal medicine. The dominant factor influencing the use of herbal medicine was its minimal side effects, whereas the main reason for choosing conventional medicine was its effectiveness in treating diseases. Descriptive analysis concluded that the productive age population tends to prefer conventional medicine over herbal medicine for daily treatment.
Paparan Sampah Elektronik dan Organik pada Pekerja Informal: Laporan Kasus dengan Implikasi Kesehatan, Lingkungan, dan Keselamatan Kerja Listina, osie; Subekti, Agung Tyas
Bhamada Occupational Health and Safety Environment Journal Vol 3 No 2 (2025): Volume 3 No 2 Desember
Publisher : LPPM Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/bohsej.v3i2.882

Abstract

This report presents an anonymous case of an informal waste picker in an urban area who was referred to a healthcare facility with complaints suggestive of hazardous exposure: chronic cough, dermatitis on the hands, mild hearing impairment, and mild neurocognitive symptoms (fatigue, difficulty concentrating). The case highlights the complex health risks associated with waste management and the urgent need to integrate occupational safety, environmental protection, and recycling policies. The investigation revealed daily work involving manual separation of electronic waste (e-waste) and organic waste without adequate protective equipment, frequent open burning of waste, and a history of chemical contact. Management included symptomatic treatment, referral to occupational health services, preventive education, and policy recommendations for improving local recycling practices and protecting informal workers. This case underscores the urgent need to protect informal workers within waste management systems. Cross-sectoral policies are required to prevent long-term health and environmental impacts.
Pola Penggunaan dan Rasionalitas Terapi Obat pada Pasien Gagal Jantung Kongestif Angkasa, Adelya Putri; Wulandari, Prihastini Setyo; Listina, Osie
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5470

Abstract

Congestive Heart Failure (CHF) is one of the cardiovascular diseases with high prevalence and significant morbidity and mortality rates, including in RSUD dr. Soeselo Tegal Regency. Rational pharmacotherapy management is crucial to reduce hospitalization rates and improve patient quality of life. This study aims to evaluate the use of drugs in hospitalized CHF patients based on the parameters of correct diagnosis, correct indication, correct drug, and correct dose. The design of this study was descriptive observational with a retrospective approach, using medical record data of CHF patients treated at RSUD Dr. Soeselo Tegal Regency during the period July-December 2023. The samples analyzed were 79 patients. The results showed that the most widely used drug classes were loop diuretics (furosemide), beta-blockers (bisoprolol, carvedilol), aldosterone antagonists (spironolactone), ARBs (candesartan), and ACE-I (ramipril, captopril). The majority of patients received therapy at doses appropriate for standard CHF therapy and the longest inpatient stay was 7 days. The evaluation showed that all patients had received therapy that met the four indicators of rational use of drugs (100% correct diagnosis, 100% correct indication, 100% correct drug, and 100% correct dose). The conclusion of this study indicates that the use of CHF drugs in hospitalized patients at RSUD Dr. Soeselo Tegal Regency has been carried out rationally and in accordance with national therapeutic guidelines
Pengukuran Quality of Life Menggunakan Kuesioner SF-36 pada Pasien Hipertensi Fahamsya, Arifina; Listina, Osie; Maulinda, Yanda Rizqi
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5485

Abstract

A rise in arterial blood pressure of 140/90 mmHg or higher is referred to as hypertension. One statistic used to assess how well health services are being prevented and treated is quality of life. Determining the characteristics of hypertension patients at the Talang Community Health Center, assessing their quality of life there, and identifying the factors affecting their quality of life were the goals of this study. This kind of study was quantitative, descriptive, and employed a cross-sectional technique. There were eighty responders in the study sample. Non-probability sampling using a successive sampling method was the sampling strategy used. The findings of the bivariate analysis indicated that the physical component summary was significantly correlated with age, gender, and duration of suffering, whereas the mental component summary was correlated with education and duration of suffering (p <0.05). The multivariate analysis's findings indicated that the physical component summary was influenced by age, gender, and length of suffering. On the other hand, the mental component summary was influenced by the length of suffering. Neither the mental nor the physical components were impacted by education. With physical component summary scores of 42.23 and mental component summary scores of 43.10, respondents with hypertension at the Talang Health Center experienced a low quality of life.