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All Journal Publikasi Pendidikan JURNAL PENDIDIKAN TAMBUSAI Jurnal Kesehatan Jurnal Riset Kefarmasian Indonesia Jurnal Aisyah : Jurnal Ilmu Kesehatan Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Pengabdian Kepada Masyarakat Ungu ( Abdi Ke Ungu) Jurnal Ilmiah Pharmacy Jurnal Ilmiah Wahana Pendidikan JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Ners Akademika International Journal of Contemporary Sciences (IJCS)
Mida Pratiwi
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Optimization of Teak Leaf Extract (Tectona grandis L.F) and Carbopol in Hair Dye Formulation Using Factorial Design Method halimah, Sofiati; Rosanti, Afi Sania; Dwiningrum, Riza; Pratiwi, Mida
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4283

Abstract

Cosmetics are preparations intended for use on the external parts of the human body, and one commonly used type is hair dye. However, many hair dye products on the market still rely on synthetic dyes, which may pose health risks such as irritation or internal organ damage if used long-term. To reduce these risks, the use of natural dyes has become an increasingly popular alternative, especially due to their content of anthocyanins that can provide natural color. One such natural ingredient is teak leaves (Tectona grandis L.F), which are rich in anthocyanin pigments and other bioactive compounds. This study aims to determine the optimal hair dye gel formulation using a combination of teak leaf extract and Carbopol, utilizing the Factorial Design method. The research was conducted observationally by preparing several formulas with varying concentrations, followed by evaluating the physical properties of each formulation, including organoleptic tests, pH, homogeneity, spreadability, adhesion, viscosity, and protective ability. The results indicated that the optimal formula consisted of 15% teak leaf extract and 2% Carbopol, showing a pH of 6.1±0.80, adhesion time of 7.74±2.41 seconds, spreadability of 6.43±0.60 cm, and viscosity of 34,000±12,124 cps. The resulting gel appeared stable, homogeneous, and capable of protecting the scalp. Therefore, the combination of teak leaf extract and Carbopol can be formulated into a natural hair dye cosmetic product that meets quality standards, offers good stability, and is safe for use.
Formulation and Evaluation of Face Mist Preparation from Ethanol Extract of Agarwood Leaves (Aquilaria malaccensis L) as an Antioxidant trijayanti, mesi; Pratiwi, Mida; Daskar, Annajim; Safutri, Wina
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4311

Abstract

Skin damage due to UV exposure and pollution can trigger the formation of free radicals that accelerate the process of premature aging. The use of natural antioxidants in cosmetic products to combat free radicals serves as an alternative to synthetic antioxidants, which often cause side effects. Agarwood leaves (Aquilaria malaccensis L.) are known to contain groups of active compounds such as flavonoids, tannins, alkaloids, saponins, and terpenoids that have potential as antioxidants. This study aims to formulate and evaluate the face mist preparation of ethanol extract from agarwood leaves in three different concentration variations: FI (5%), FII (6%), and FIII (7%). The research was conducted experimentally in the laboratory, covering the stages of plant determination, maceration with 96% ethanol, phytochemical screening, formulation of preparations, physical evaluation (organoleptic, homogeneity, pH, specific gravity, spreadability, spray condition, drying time, protection, and stability through cycling tests), as well as antioxidant activity testing using the DPPH method with UV-Vis spectrophotometry. The results showed that all formulations had good physical characteristics and were stable using the cycling test method, except for FII which was unstable in the specific gravity test. The IC₅₀ values of each formulation were FI at 28.138 mg/L, FII at 21.871 mg/L, and FIII at 19.387 mg/L, categorized as very strong antioxidants and the three formulations had significant differences with a p-value of ˂0.05. The conclusion of this research is that the FIII formula (7%) is the best formula because it has high antioxidant activity, is stable physically and chemically, and has the potential as a natural cosmetic product that protects the skin from free radicals.
Synergistic Antihyperglycemic Effects of Soursop Leaves and Garlic in Alloxan-Induced Rats Suswidiantoro, Vicko; Safutri, Wina; Pratiwi, Mida; Putri, Diah Karika; Dwiningrum, Riza; Lestari, Fina Aulika
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 12 (2024): October 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i12.12038

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels due to impaired insulin production. Natural remedies, such as soursop leaves (Annona muricata) (SL) and garlic (Allium sativum) (GAR), are known for their antihyperglycemic properties. This study aimed to investigate the effects of SL and GAR extracts, individually and in combination, on reducing blood glucose levels in alloxan-induced diabetic rats. A total of 24 male Wistar rats were divided into six groups, receiving treatments of either metformin, SL, GAR, or their combination for seven days following alloxan administration to induce hyperglycemia. Blood glucose levels were measured before and after induction, and post-treatment on day 15. The results showed that the combined extracts exhibited better antihyperglycemic activity compared to individual treatments, with the most effective dose being 26.3 mg/kg BW SL + 31.5 mg/kg BW GAR.
The Correlation between Knowledge Level and Gout Prevention Behavior among the Elderly in Kresnomulyo Village, Ambarawa District, Pringsewu Regency, Lampung Winabila, Putri; Safutri, Wina; Pratiwi, Mida; Dwiningrum, Riza
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 3 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i3.4307

Abstract

Gout is a purine metabolism disorder characterized by increased levels of uric acid in the blood, leading to the accumulation of uric acid crystals and joint pain, particularly among the elderly. Knowledge about gout prevention behavior in the elderly significantly affects the success of gout management. Gout management is essential to prevent long-term complications such as joint damage and kidney stones. This study aims to determine the relationship between knowledge level and gout prevention behavior among the elderly in Kresnomulyo Village, Ambarawa District, Pringsewu Regency, Lampung. This study was a descriptive quantitative study with a cross-sectional design. The sampling technique used purposive sampling based on inclusion and exclusion criteria, with a total of 110 respondents. The results showed that 31% of respondents had a moderate level of knowledge, while 79% had a low level of knowledge. In terms of behavior, 100% of respondents exhibited poor gout prevention behavior. The Chi-Square test results showed an Asymp. Sig value of 0.000 < 0.05, indicating a significant relationship between knowledge and gout prevention behavior among the elderly in Kresnomulyo Village, Ambarawa District, Pringsewu Regency, Lampung. Village administrators can actively contribute to enhancing community awareness about gout prevention by conducting educational initiatives and implementing practical programs. Furthermore, promoting sufficient water intake, regular physical activity, and a balanced diet through Posyandu or local community gatherings is essential.
Antibacterial Effectiveness Test on the Combination of Kersen Leaf (Muntingia calabura L.) and Jackfruit Leaf (Artocarpus heterophyllus L.) Extracts Against The Growth of Staphylococcus aureus Bacteria Mahendri, Adelia Citra; Suswidiantoro, Vicko; Pratiwi, Mida; Pisacha , Iga Mayola
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 3 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i3.4366

Abstract

Kersen leaves (Muntingia calabura L.) and jackfruit leaves (Artocarpus heterophyllus L.) are tropical plants that grow in Indonesia. The phytochemical content of kersen leaves and jackfruit leaves include flavonoids, tannins and saponins. Flavonoids have antibacterial properties because they can fight bacteria in several ways. These substances can interfere with the formation of bacterial genetic material (nucleic acids), damage cell membranes that maintain the contents of bacterial cells, and inhibit the processes used by bacteria to produce energy. This study aims to determine the effectiveness of secondary metabolite compounds against the growth of Staphylococcus aureus bacteria contained in kersen leaves and jackfruit leaves. The research method used is experimental. The sample in this study was a combination of 96% ethanol extract of kersen leaves (Muntingia calabura L.) and jackfruit leaves (Artocarpus heterophyllus. L). The yield of extracts obtained in kersen leaves amounted to 32.1% and avocado leaves 25.42%. Phytochemical screening showed that both samples contained secondary metabolites such as flavonoids, tannins and saponins. The combination of kersen leaf and jackfruit leaf extracts at a concentration ratio of 80:50% and has an average inhibition zone with high effectiveness of 11.10 mm which is classified as strong. This shows that there is a difference, the inhibition zone is better than ampicillin in inhibiting Staphylococcus aureus bacteria.
Formulation And Physical Evaluation Of Face Mist Containing Cucumber (Cucumis sativus L.) Extract As a Facial Moisturizer Putri, Elsa Claudia; Dwiningrum, Riza; Pratiwi, Mida; Safutri, Wina
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 3 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i3.4369

Abstract

Face mist is a skin-refreshing product that primarily functions to hydrate the facial skin and is effective in maintaining skin moisture, as well as preventing skin damage caused by free radicals from air pollution. One plant known as a source of antioxidants is cucumber (Cucumis sativus L.), which contains antioxidants, vitamins, minerals, and phytochemical compounds such as flavonoids, terpenoids, and saponins that nourish and help retain skin moisture.This study aims to determine the optimal concentration of cucumber extract in a face mist formulation that provides the best moisturizing effect on facial skin. The research employed an experimental method by formulating cucumber extract face mist, followed by evaluation of its physical properties, including organoleptic test, homogeneity test, pH test, specific gravity test, spray dispersion test, spray condition test, drying time test, protection ability test, stability test, preference test, and moisturizing test.Results indicated that cucumber extract contains flavonoids, saponins, and terpenoids with potential moisturizing properties. The face mist formulations with concentrations F0 (0%), F1 (1%), F2 (3%), and F3 (5%) demonstrated good physical stability both before and after the stability test over the designated time period. F0 (0%) and F1 (1%) were the most preferred by panelists for colour and absorption properties, while F1 (1%) was the most preferred in terms of aroma. In the moisturizing test, the increase in skin moisture levels before and after treatment were F0: 10.6%, F1: 10.2%, F2: 10.9%, and F3: 11.3%. The conclusion of this study is that the best results were obtained at concentrations F5 and F1 which provided stable physical properties and a good level of panellist preference, so that this face mist preparation has he the potential to be used as a natural facial moisturizer.
FORMULASI DAN UJI EVALUASI FISIK SEDIAAN GEL PEEL-OFF SEBAGAI MASKER WAJAH DARI SARI WORTEL (DAUCUS CAROTA L.) Alensia Putri, Nofellia; Dwiningrium, Riza; Suswidiantoro, Vicko; Pratiwi, Mida
Jurnal Riset Kefarmasian Indonesia Vol. 7 No. 3 (2025): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/v7i3.792

Abstract

Carrots (Daucus carota L.) are rich in beta-carotene, vitamins A, C, and E, which possess antioxidant activity and potential for use as active ingredients in cosmetic formulations. This study aimed to formulate and evaluate the physical characteristics of peel-off gel mask preparations containing carrot juice at varying concentrations. A laboratory-based experimental design was used to develop three formulations containing 5 %, 10 %, and 15 % carrot juice. Physical evaluations included organoleptic properties, homogeneity, pH, drying time, spreadability, adhesiveness, protective effect, and skin moisture. All formulations demonstrated acceptable physical stability. The 10% concentration formula showed the most ideal drying time, balanced spreadability and adhesiveness, and the most significant increase in skin moisture. These findings indicate that carrot juice can be effectively used as a single active ingredient in peel-off gel mask formulations, with 10 % identified as the most optimal concentration. For future development, further studies are recommended to include long-term stability testing, dermatological evaluations on human subjects, and exploration of combinations with other natural ingredients to enhance effectiveness and support broader applications in herbal-based cosmetic industries.
Co-Authors Alensia Putri, Nofellia Ayu, Fadillah Bastian, Arif Alexander Bayu Satriawan, Ahmad Damayanti Abdul Karim, Dewi Daskar, Annajim Dwiningrium, Riza Eka Pratiwi Yunianti Em Sutrisna Fadia Zahra, Alya Gustianing, Defy halimah, Sofiati Katika Putri, Diah Lestari, Fina Aulika Mahendri, Adelia Citra Marsanda, Adelia Mayola Pisacha, Iga Munawaroh, Iis Hapson Mustika, Nabila P, Fadillah Ayu S.W. Pisacha , Iga Mayola Puspita, Cici Chandra Putri, Diah Karika Putri, Diah Kartika Putri, Elsa Claudia Riza Dwiningrum, Riza Rosanti, Afi Sania Safitri, Indah Sania Rosanti, Afi Sari, Yuhana Satriawan, Ahmad Bayu Septiana, Elen Setyani, Elsa Dewi Suswidiantoro, Vicko Syaifurrahman, Amir Syamsuri, Eddy Syamsuri, Edy trijayanti, mesi Uswatun Hasanah Wati, Desti Ambar Wina Safutri Winabila, Putri Wisnu Probo Wijayanto Wiwi Febriani Yanti, Erna Yulianti Yulianti Yulinda, Gita Yuniyarti, Lisa