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All Journal HAYATI Journal of Biosciences Jurnal Neutrino : jurnal fisika dan aplikasinya MPI (Media Pharmaceutica Indonesiana) Jurnal Kimia Riset JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya Jurnal Penelitian Pendidikan IPA (JPPIPA) Stigma : Jurnal Matematika dan Ilmu Pengetahuan Alam Unipa Pharmaceutical Sciences and Research (PSR) Jurnal Tumbuhan Obat Indonesia Jurnal Sains dan Kesehatan
Budipramana, Krisyanti
Department Of Pharmaceutical Biology, Faculty Of Pharmacy, University Of Surabaya, Surabaya 60293, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health

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The Antibacterial Activities of Piper betle and Allium cepa Extracts Against Staphylococcus aureus Setiawan, Vendra; Triono, Nathanel; Agustina, Astrid Karindra; Moira, Lovely Anastasia; Biutifasari, Verna; Budipramana, Krisyanti
Jurnal Penelitian Pendidikan IPA Vol 11 No 9 (2025): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i9.10850

Abstract

Indonesia rich in biodiversity, both animals and plants. This is known as ethnobotany. Local people learn to use natural herbs to meet their daily needs, and some commonly used herbs are Piper betle (betel leaf) and Allium cepa (red onion). They often use P. betle or A. cepa to cure various skin infections, one of which is furuncles. This study aimed to explore ethanol extracts of P. betle, A. cepa, and their combination against Staphylococcus aureus, the main bacterial cause of furuncles, using petri dish. The inhibition zones in petri dishes were measured using a caliper to evaluate the antibacterial efficacy. Each sample was tested with 3 replicates and kanamycin was used as positive control. The P. betle extract exhibited the strongest inhibitory effect with an inhibition zone of 17.70 ± 0.30 mm, followed by P. betle and A. cepa with ratio 1:1 produced an inhibition zone of 15.63 ± 0.58 mm. The ethanol extract of A. cepa showed the lowest inhibition zone only 14.38 ± 0.35 mm and this inhibition zone was similar to that of kanamycin as positive control.
A Review of Fungal-Derived Natural Dyes: Chemical Diversity and Multifaceted Health Benefits Budipramana, Krisyanti; Setiawan, Vendra; Ratih, Ratih; Budi Pramana, Yanatra
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 2 (2024): December 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i2.1047

Abstract

Various industrial sectors, from food and drug production to textiles, have widely used pigments or dyes as coloring agents. Generally, we can distinguish between two types of coloring agents: synthetic and natural. Currently, the use of synthetic colorings is a topic of debate due to their potential health risks, toxicity, and environmental pollution. This prompts a deeper exploration of natural resources as a more secure substitute for coloring agents. Plants, animals, microbes, and fungi can all provide natural coloring agents. Besides animals and microbes, some challenges in developing plants as major sources of natural coloring agents include variations in production or harvest times, strongly influenced by season, weather, and the intensity of sunlight. These factors influence not only the stability of the produced color but also its physicochemical properties, such as solubility and pH.  Moreover, overexploitation of plants has an impact on ecosystem imbalances and leads to extinction. Among natural resources, pigments or dyes from fungi have shown their potential to address these challenges. This review focuses on the potential of various microfungi that produce natural dyes, especially from Monascaceae, Trichocomaceae, and Nectriaceae, as well as the classification based on their chemical structure. Furthermore, we describe their diverse biological impacts as antioxidants, antibiotics, antidiabetics, anticancer agents, and anti-cholesterol agents, along with their health advantages.
Effect of Tween 20 on the Electrochemical Synthesis and Properties of Nickel Hydroxide Nanoparticles Pramana, Yanatra Budi; Asranudin; Budipramana, Krisyanti
Jurnal Kimia Riset Vol. 10 No. 2 (2025): December
Publisher : Universitas Airlangga, Campus C Mulyorejo, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkimris.v10i2.76614

Abstract

Nickel (II) hydroxide (Ni(OH)₂) nanoparticles have attracted significant research interest due to their potential in applications such as supercapacitors, batteries, and electrocatalysis. However, conventional synthesis methods often face challenges related to high costs and complex instrumentation. This study presents a simple, low-cost, and controllable approach for synthesizing Ni(OH)₂ nanoparticles using a surfactant-assisted electrochemical method. The synthesis was conducted through electrolysis at 100°C in an aqueous solution containing sodium citrate, with Tween 20 employed as a structure-directing agent, Tween 20 was effective in producing smaller, dispersed, quasi-spherical particles while preventing severe agglomeration. The resulting nanoparticles were characterized using various analytical techniques, including UV-Vis and FTIR spectroscopy, X-ray Diffraction (XRD), Thermal Gravimetric Analysis (TGA), and electron microscopy (TEM/SEM). UV-Vis analysis showed a characteristic absorption peak at 387 nm, confirming nanoparticle formation. XRD analysis validated the synthesis of a nanocrystalline hexagonal Ni(OH)₂ phase. Electron microscopy revealed a hierarchical, flower-like morphology composed of nanosheets and demonstrated that Tween 20 was effective in producing smaller, dispersed, quasi-spherical particles while preventing severe agglomeration. Furthermore, the thermal decomposition of Ni(OH)₂ into highly crystalline cubic, NiO via calcination was confirmed by TGA, XRD, and FTIR analyses, with the main decomposition occurring at approximately 335°C. This research demonstrates an effective and economical route for producing Ni(OH)₂ nanoparticles with controlled morphology, enhancing their potential for practical applications.
Co-Authors Adang Firmansyah Agustina, Astrid Karindra Amelia Lorensia Amilia, Eva Anita Purnamayanti Asranudin Ayu Titisari, Manik Biutifasari, Verna Bramianto Setiawan Budi Pramana, Yanatra Djoko Adi Walujo Elfahmi Elfahmi, Elfahmi Fauziatul Fajaroh Frangky Sangande Huda, Miftakul Indah Nurhayati Marisca Evalina Gondokesumo, Marisca Evalina Marthy Meliana Ariyanti Jalmav Moira, Lovely Anastasia Pramana, Yanatra Budi Pratama, Anggara Martha Prihono Prihono, Prihono Putranti, Astridani Rizky Raharjo, Dian Natasya ratih ratih Rissyelly Rissyelly Setiawan, Vendra Subandowo, Marianus Sukrasno Sukrasno Suryadinata, Rivan Virlando Syaikhul Aziz Triono, Nathanel Wardani, Mariani Ika Wijaya, Yeremia Tanu Yanatra Budi Pramana Yitno Utomo Yodha, Agung Wibawa Mahatva Zulfikar Ainunsidiq, Mohammad