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Analisa Hasil Pemeriksaan Dahak Suspek TB dengan Genexpert (TCM) dan Pewarnaan Ziehl Neelsen di Rumah Sakit Umum Daerah Pandan Suventy Safrina Ginting; Penny Ariani; Viktor Edyward Marbun; Nadya Juliesti
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 1 (2025): Juni 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i1.11965

Abstract

Tuberkulosis (TB) merupakan penyakit menular dengan prevalensi tinggi di Indonesia. Diagnosis masih banyak menggunakan metode Ziehl Neelsen yang kurang sensitif, sedangkan GeneXpert (TCM) lebih akurat dan cepat. Penelitian ini bertujuan membandingkan hasil pemeriksaan dahak suspek TB dengan GeneXpert dan Ziehl Neelsen di RSUD Pandan. Penelitian deskriptif potong lintang ini menggunakan 30 sampel dahak pasien suspek TB pada Januari–Juni 2024. Hasil GeneXpert menunjukkan MTB Not Detected 76,7%, Low 6,7%, Medium 10%, High 6,7%. Sementara Ziehl Neelsen menunjukkan negatif 83,3%, positif 2 sebanyak 10%, dan positif 3 sebanyak 6,7%. Kesimpulan: GeneXpert lebih sensitif dalam mendeteksi Mycobacterium tuberculosis dibandingkan Ziehl Neelsen
PENGARUH PEMBERIAN INFORMASI OBAT TERHADAP KEPATUHAN PENGGUNAAN OAT PADA PASIEN TB PARU DI RUMAH SAKIT TK III IM 07.01 LHOKSEUMAWE Anggun Syafitri; Viktor Edyward Marbun; Hazimah Fitriyah Mardatilah; Mezz Nazly Siti Rofieqoh
Jurnal Penelitian Farmasi & Herbal Vol. 9 No. 1 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/5vh2rb33

Abstract

Pulmonary tuberculosis (TB) is a contagious disease that requires long-term treatment using anti-tuberculosis drugs (OAT). Non-adherence to OAT treatment can lead to treatment failure, drug resistance, and an increase in morbidity and mortality rates. One important strategy to improve treatment outcomes is the proper provision of drug information (PIO) to patients. This study aimed to determine the effect of drug information provision on adherence to OAT use in pulmonary TB patients. This research employed a quantitative method with a quasi-experimental design involving two groups of patients: those who received drug information and those who did not. Adherence levels were measured using the MMAS-8 questionnaire. The results showed a significant difference in adherence levels between the two groups, with the PIO group demonstrating a higher level of adherence. It can be concluded that drug information provision by pharmaceutical personnel has a positive effect on improving patient adherence to OAT. The study recommends integrating PIO into routine clinical pharmacy services in healthcare facilities to support the success of TB treatment.