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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Medical Journal of Indonesia Journal of General Procedural Dermatology and Venereology Indonesia JOURNAL LA MEDIHEALTICO eJournal Kedokteran Indonesia Media Dermato-Venereologica Indonesiana Journal of General-Procedural Dermatology & Venereology Indonesia Bali Dermatology Venereology and Aesthetic Journal Jurnal MedScientiae Jurnal Kedokteran Meditek
Lili Legiawati
Department Of Dermatology & Venereology, Faculty Of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Hospital, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Journal : Jurnal Kedokteran Meditek

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Perbaikan Klinis Green Nail Syndrome yang Signifikan pada Lanjut Usia dengan Terapi Kombinasi: Sebuah Serial Kasus Marizki Ramadhani, Reinanda; Nadia Yusharyahya, Shannaz; Legiawati, Lili; Astriningrum, Rinadewi; Gunardi, Keiko Yolanda; Reshinta, Reisa
Jurnal Kedokteran Meditek Vol 31 No 2 (2025): MARCH
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i2.3383

Abstract

Introduction: Green nail syndrome is a common bacterial infection of the nails and is characterized by green discolouration of the nail plate caused by Pseudomonas aeruginosa. It frequently occurs in people who are exposed to constant water and due to mechanical trauma, especially in elderly patients. Case Illustration: We reported 2 cases treated with a combination therapy of oral ciprofloxacin, 1% acetic acid dressing, gentamicin ointment and showed a significant clinical improvement. There are two cases: a 67-year-old man and a 64-year-old woman complained of black-greenish discolouration on his right big toenail, which has been accompanied by changes in the shape of the nail for 3 months. Both patients have a history of frequent and prolonged contact with water—dermoscopy results in greenish-black discolouration in the nail plate.  The culture results of both patients, Pseudomonas aeruginosa was found. Combination treatment showed significant clinical improvement in both patients. Discussion: Dressing of 1% acetic acid was useful as an adjuvant to improve the ointment penetration, inhibiting the formation of Pseudomonas aeruginosa biofilms. Gentamicin and ciprofloxacin are effective against aerobic gram-negative bacterial infections, such as Pseudomonas aeruginosa. Conclusion: The use of ciprofloxacin is recommended, especially in elderly patients. Combination therapy with oral ciprofloxacin, 1% acetic acid dressing, and gentamicin ointment is an effective option for patients with green nail syndrome
Co-Authors Adistri, Kara Andhira, Vega Astriningrum, Rinadewi Barros, Terlinda Batubara, Irwan Bianti, Marsha Chairista, Inadia Putri Chandrakesuma, Vivianne Endi Novianto Evita H. Effendi Fauziah, Siti Nurani Fifi Mifta Huda Gunardi, Keiko Yolanda Halim, Dionisius Ivan Yonathan Hartanto, David Dwiadiputra Hoemardani, Aida SD Huda, Fifi Mifta Imelda Wihadi Indah Widyasari Irawan, Yudo Jonlean, Reganedgary Keumala Budianti, Windy Krisanti, Roro Inge Ade Krisanti, RR Inge Ade Kusmarinah Bramono Kusumawardhani, Dina Larisa Paramitha Marizki Ramadhani, Reinanda Marsha Bianti Melody Febriana Andardewi Miranda, Eliza Muhammad, Parikesit Nadia Yusharyahya, Shannaz Nadia, Department of Dermatology and Venereology, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital Jakarta, Indonesia Shannaz, Yusharyahya Nugraheni Pasaribu, Uly Aanda Maria Pandjaitan-Sirait, Sondang MHA Priyanto, Mufqi Handaru Rahadi Rihatmadja Rahadi Rihatmadja Reshinta, Reisa Rheza, Agung Mohamad Rinadewi Astriningrum Rosdiana, Dewi Selvina Sampurna, Adhimukti T Sandra Widaty Shannaz Nadia Yusharyahya Sirait, Sondang P. Siskawati, Yulia Siti Nurani Fauziah Sitohang, Irma Bernadette Sitohang, Irma Bernadette Simbolon Sondang P Sirait Sri Adi Sularsito Sri Adi Sularsito Sri Adi Sularsito Sri L. Menaldi Sujudi, Yufanti Suseno, Lis Surachmiati Terlinda Barros Vivianne Chandrakesuma Wahyudi, Danang T Wardani, Amanda Nandi Widyasari, Indah Wihadi, Imelda Windy Keumala Budianti Wresti Indriatmi B. Makes Yudo Irawan Yudo Irawan