Garuda - Garba Rujukan Digital

Pengaruh Konsumsi Alkohol terhadap jumlah Eritrosit dan Hemoglobin Mencit (Mus musculus) Raudhah Hayatillah; Widie Kemala Hapsari; Syukriah Syukriah
KLOROFIL: Jurnal Ilmu Biologi dan Terapan Vol 5, No 2 (2021): KLOROFIL: JURNAL ILMU BIOLOGI DAN TERAPAN
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30821/kfl:jibt.v5i2.10335

Alcohol is an organic compound that is often used in our life. In science research, alcohol is used as a solvent, fuel, and antiseptic. Alcohol if consumed in large quantities has side effects on the body that affect physiologically, one of which is nerve damage, liver and kidney damage, and affects the fetus if consumed by pregnant women. In addition, it is known that alcohol can affect erythrocytes and hemoglobin. In this study, alcohol was given to mice (Mus musculus) to see the effect on the number of erythrocytes and hemoglobin. This study used beer concentrations of 4% and 1% and distilled water as a control. The experimental animals used were 9 mice which would be induced by 1 mL of alcohol for 5 days. The parameters used were the number of erythrocytes and hemoglobin. Data collection was carried out 3 times after 5 days of alcohol induction. The result of this study is that alcohol can reduce the number of erythrocytes and hemoglobin in mice. Decreased erythrocytes and hemoglobin in mice Â have an impact on other body organ damage.

Pengaruh Konsumsi Alkohol terhadap jumlah Eritrosit dan Hemoglobin Mencit (Mus musculus) Raudhah Hayatillah; Widie Kemala Hapsari; Syukriah Syukriah
KLOROFIL: Jurnal Ilmu Biologi dan Terapan Vol 5, No 2 (2021): KLOROFIL : JURNAL ILMU BIOLOGI DAN TERAPAN
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30821/kfl:jibt.v5i2.10335

Alcohol is an organic compound that is often used in our life. In science research, alcohol is used as a solvent, fuel, and antiseptic. Alcohol if consumed in large quantities has side effects on the body that affect physiologically, one of which is nerve damage, liver and kidney damage, and affects the fetus if consumed by pregnant women. In addition, it is known that alcohol can affect erythrocytes and hemoglobin. In this study, alcohol was given to mice (Mus musculus) to see the effect on the number of erythrocytes and hemoglobin. This study used beer concentrations of 4% and 1% and distilled water as a control. The experimental animals used were 9 mice which would be induced by 1 mL of alcohol for 5 days. The parameters used were the number of erythrocytes and hemoglobin. Data collection was carried out 3 times after 5 days of alcohol induction. The result of this study is that alcohol can reduce the number of erythrocytes and hemoglobin in mice. Decreased erythrocytes and hemoglobin in mice have an impact on other body organ damage.

Review Artikel: Potensi Tenggek Burung (Melicope ptelefolia) sebagai Kandidat Obat Widie Kemala Hapsari; Raudhah Hayatillah
Jurnal Tadris IPA Indonesia Vol. 3 No. 1 (2023)
Publisher : Tadris IPA IAIN Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21154/jtii.v3i1.1572

Tenggek burung (Melicope ptelefolia) merupakan famili Rutaceae, merupakan tanaman herba yang dapat hidup setinggi 1-14 m, banyak ditemukan di daerah Riau, dan juga ditemukan di Malaysia, Vietnam dan China. Tenggek burung biasa dikonsumsi dan dimanfaatkan dalam kehidupan sehari-hari dan diyakini memiliki manfaat secara klinis. Tujuan penulisan artikel ini adalah untuk mengetahui potensi tenggek burung sebagai kandidat tanaman obat. Metode yang digunakan adalah studi literatur, literatur online didapat dari jurnal publikasi lokal maupun internasional yang diperoleh dari penyedia jurnal di internet menggunakan mesin pencari google. Hasil yang didapat menunjukkan bahwa tanaman tenggek burung memiliki kandungan metabolit alam yang dapat berperan sebagai antioksidan, tenggek burung diketahui memiliki senyawa bioaktif seperti fenolik, flavonoid, saponin dan senyawa bioaktif lainnya. Kandungan senyawa bioaktif tersebut dapat berperan sebagai penangkal radikal bebas untuk menggurangi terjadinya stres oksidatif, selain itu adanya kandungan bioaktif yang terkandung pada tanaman tenggek burung membuat tanaman ini memiliki potensi sebagai kandidat obat yang dapat dikembangkan dikemudian hari.

Anti-Inflamasi Tanaman Kedondong (Spondias Dulcis G. Forst.): Review Raudhah Hayatillah; Widie Kemala Hapsari
Jurnal Sains dan Pendidikan Biologi Vol 2 No 1 (2023): April 2023
Publisher : Universitas Muslim Buton

Show Abstract | Download Original | Original Source | Check in Google Scholar

Technological developments are currently growing, this can be seen from the increasing lifestyle of people, one of which is the increased consumption of fast food or junk food, it is known that fast food has low nutritional content and high calories, so it can trigger inflammation in the body accompanied by the emergence of disease. which is harmful to the body if consumed for a long time. To minimize the occurrence of disease, in recent years scientists have been intensively conducting research on the discovery of new drugs derived from plants, one of the plants that has the potential as an anti-inflammatory is the kedondong plant. The purpose of writing this article is to find out the potential of the kedondong plant as an antioxidant and anti-inflammatory. Based on testing with several extraction methods and compound test methods, bioactive compounds were found, the compounds contained were phenolics, tannins, saponins and flavonoids which are a group of antioxidant compounds. These compounds were found in leaves, stems, fruits and roots, every part of the kedondong plant has bioactive compounds, through tests carried out. The bioactive compounds in kedondong are known to reduce the expression of iNOS, TLR4, Th1, interleukin (IL) and cytokines genes, these genes are expressed genes in the process of inflammation. So that the antioxidant content in the kedondong plant has the potential as an anti-inflammatory by inhibiting the genes that are expressed in the process of inflammation. The content of bioactive compounds contained is also influenced by the solvent in the extraction process carried out.

Pengaruh Konsumsi Alkohol terhadap Subkronik Hepar dan Keseimbangan Tubuh pada Mencit (Mus musculus) Hayatillah, Raudhah; Hapsari, Widie Kemala
Jurnal Jeumpa Vol 9 No 2 (2022): Jurnal Jeumpa
Publisher : Department of Biology Education, Faculty of Teacher Training and Education, Samudra University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Alkohol merupakan salah satu senyawa organik yang banyak digunakan dalam kehidupan sehari-hari, seperti dalam bidang penelitian digunakan sebagai bahan sterilisasi, antiseptik, pelarut senyawa, selain itu alkohol juga dapat dikonsumsi dalam jumlah dan kadar tertentu, jika alkohol dikonsumsi dalam jumlah yang berlebihan dan terus menerus, maka dapat merusak organ tubuh yang dapat mempengaruhi homeostasis. Untuk melihat pengaruh alkohol pada tubuh, maka dilakukan penelitian untuk mengamati kerusakan hepar subkronis dan keseimbangan akibat pemberian alkohol pada mencit, metode yang digunakan adalah mengamati morfologi hepar, indeks hepatosomatik, menghitung kadar serum glutamat piruvat transaminase (SGPT) dan uji berenang paksa. Hasil penelitian menunjukkan bahwa alkohol dapat menyebabkan kerusakan subronik pada hepar dan keseimbangan tubuh pada mencit, kerusakan hepar mencit dapat mempengaruhi metabolisme dan fungsi organ tubuh lainnya. Alkohol diketahui dapat mengativasi sel kupffer untuk memproduksi mediator toksik yang dapat menyebabkan kerusakan pada hepar, selain itu alkohol juga menyebabkan penghambatan neurotransmitter berupa sel GABA yang menghalangi penyampaian implus.

ANALISIS KANDUNGAN AGAR, PROKSIMAT DAN PIGMEN RUMPUT LAUT Gracilaria sp. PADA PERAIRAN ULEE LHEUE KECAMATAN MEURAXA KOTA BANDA ACEH Haikal, Muhammad; Nasution, Reni Silvia; Yulian, Muammar; Hayatillah, Raudhah
KENANGA : Journal of Biological Sciences and Applied Biology Vol. 4 No. 2 (2024): Oktober 2024
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Ar-Raniry Banda Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/kenanga.v4i2.5525

Gracilaria sp. adalah salah satu spesies rumput laut yang memiliki kandungan agar, proksimat dan pigmen. Ketiga kandungan tersebut banyak digunakan dalam bidang industri, bioteknologi dan sebagai makanan yang baik dan sehat.Penelitian ini menggali potensi budidaya Gracilaria sp. di sepanjang pesisir Ulee Lheue, Kota Banda Aceh, berdasarkan kandungan agar, proksimat dan pigmen. Metode yang digunakan pada penelitian ini untuk analisis Agar adalah gravimetri dan dikarakterisasi menggunakan FTIR, untuk analisis proksimat mengacu pada metode standar Associationof Official Analytical Chemists (AOAC). Pengujian pigmen menggunakan metode maserasi tunggal serta dikarakterisasi menggunakan UV-Vis. Hasil yang diperoleh bahwa kadar agar rumput laut Gracilaria sp. sebesar 17,1%. Untuk kadar proksimat yaitu kadar abu 12,46 %, kadar air 11,04 %, kadar lemak 1.63 %, kadar protein 13.32%, dan kadar karbohidrat 61,55 %. Kadar pigmen rumput laut Gracilaria sp. diperoleh sebesar 5,28 %, kadar klorofil a 3,43 μg⁄g dan kadar karotenoid 1,6 μg⁄g.

PENGARUH PEMBERIAN AIR KELAPA (Cocos nucifera L.) DAN AIR CUCIAN BERAS TERHADAP PERTUMBUHAN TANAMAN BAWANG DAUN (Allium fistulosum L.) Nanda Raudhatul Jannah; Muslich Hidayat; Raudhah Hayatillah
KENANGA : Journal of Biological Sciences and Applied Biology Vol. 4 No. 1 (2024): April 2024
Publisher : Program Studi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri Ar-Raniry Banda Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

The scallion (Allium fistulosum L.) is a type of horticultural plant that is in great demand by the people. This study aims to identify the effects the growth of plants a scallion grow regulation (GR) with a combination of coconut water and leri water. The draft in this research is a random group rack consisting of 5 treatment by 5 repetition, the treatment consists of (P0 : control), (P1: 80% coconut water and 20% leri water), (P2 : 60% coconut water and 40% leri water), (P3: 40% coconut water and 60% leri water and (P4 : 20% coconut water and 80% leri water). Parameter observed in this study is leaf length number of leaves and a heavy wetness perpolybag. The result showed that the GR from the combination of coconut water and leri water affected the growth of leaf length, number of leaves and a heavy wetness perpolybag. The best GR combination treatment is the P4 treatment with a concentration of 20% coconut water and 80% rice washing water, namely leaf length (31.28 cm) and wet weight (5.8 g).

OPTIMALISASI MANAJEMEN HIPERTENSI PADA LANSIA DI WILAYAH PESISIR KAMPUNG MELAYU, AMPENAN NTB Rozikin, Rozikin; Adyana, Angga; Setyaningrum, Tri Wahyu; Widyaswara, Gravinda; Hapsari, Widie Kemala; Hayatillah, Raudhah
Jurnal Abdi Insani Vol 12 No 3 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i3.2208

High blood pressure, also known as hypertension, is a medical condition that affects blood pressure and can lead to complications such as stroke and heart disease. Hypertension is suffered by many people living in coastal areas due to an unhealthy lifestyle and consuming salty fish. To reduce the number of people with hypertension in coastal areas, community service activities related to hypertension management were carried out. The methods used in the community service were problem identification with the Delbecq (non-scoring method) method, data collection through interviews with questionnaires and observations of 70 participants, problem intervention through poster counseling and tension checks, data analysis using univariate analysis. The results of the community service were dominated by 55 women (79%) and middle-aged (45-59 years) 46 people (66%). The results of the questionnaire search showed that as many as 60 people (86%) respondents had heavy physical activity, 39 people (56%) respondents had a good level of knowledge and hypertension management, 42 people (60%) were known to often consume salted fish and 48 people (69%) were found to have hypertension. The high rate of hypertension sufferers in the coastal area of Kampung Melayu is due to the lack of counseling that focuses on dietary management and increasing public awareness about the risk of hypertension related to the consumption of high-sodium foods.

Teratogenic Test of Jamblang Fruit Extract (Syzygium cumini) on the Fetus Mice (Mus musculus) Dewi, Cut Nur Kemala; Sari, Ayu Nirmala; Hayatillah, Raudhah
Biodidaktika : Jurnal Biologi dan Pembelajarannya Vol 20, No 2 (2025)
Publisher : Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/biodidaktika.v20i2.29255

Jamblang fruit (Syzygium cumini) is used to treat diabetes mellitus, pain, inflammation, ulcers, and diarrhea, and in recent research, it has been proven to be used as a chemopreventive, radioprotective, and antineoplastic. Jamblang fruit contains several ingredients, namely: alkaloids, saponins, tannins, triterpenoids, flavonoids, polyphenols, and buchard. However, it is necessary to ensure whether jamun is safe for consumption by pregnant women, and a teratogenic test is needed. This research aims to determine the effect of jamblang fruit extract on maternal weight, number of fetuses, fetal length, fetal weight, hemorrhage, and morphological abnormalities in the fetus. This research is included in quantitative research using experimental methods with a Completely Randomized Design (CRD), which consists of 4 treatments and 5 replications. The experimental animals used were 20 female mice (Mus musculus) of the Balb/C strain, healthy mice aged 2 months, weighing 27-30 grams, and the mice were mature and ready to mate. Mice were divided into 4 treatment groups, namely the control group, the 100 mg/kgBB dose group, the 200 mg/kgBB dose group, and the 300 mg/kgBB dose group. Treatment doses of jamun fruit extract 70% ethanol are given on days 6 to 17 of pregnancy. Data analysis using SPSS showed that ethanol 70 % extract of jamblang fruit had no effect on maternal weight and fetal weight in mice (>0.05), but did affect fetal length, number of fetuses, hemorrhage, and morphological abnormalities in the form of open eyelids (p<0.05). Based on the research results, it can be concluded that administration of jamblang fruit ethanol extract can reduce fetal length and the number of fetuses. The 200 mg/kgBB and 300 mg/kgBB dose groups are doses that can cause teratogenic effects such as hemorrhage and open eyelids.

Potensi Bunga Cempaka Kuning Magnolia champaca (L.) Baill. Ex Pierre Sebagai Antiinflamasi Hayatillah, Raudhah; Hapsari, Widie Kemala
Samota Journal of Biological Sciences Vol 3 No 1 (2024): Samota Journal of Biological Sciences
Publisher : University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjbios.v3i1.3774

Yellow champaca is a family of Magnoliaceae, which is designated as the identity of the Nanggroe Aceh Darusalam area, known as Bungong Jeumpa. Yellow champaca contains phytochemicals which can act as antioxidants and can act as an anti-inflammatory, so yellow champaca is widely used as a medicinal plant. Compounds contained in yellow chrysanthemum such as tannins, flavonoids, alkaloids, saponin, sterols and others can act as anti-inflammatories by inhibiting the action of inflammatory media which play a role in the process of inflammation. Yellow champaca is scientifically proven to have anti-inflammatory benefits. Present studi is a compilation of several aspects the indicate that Yellow champaca has potential as an anti-inflammatory which was tested based on content of secondary metabolite compounds.

Title

Found 13 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 13 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 13 Documents
Search