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Sosialisasi Bahaya Konsumsi Gula Berlebihan dan Dampaknya bagi Kesehatan Masyarakat di Kota Pekan Baru Anggraini, Deni; Sinata, Novia; Agistia, Nesa; Almurdani, M.; Sandra, Alya Dwi; Al-Fadillah, Annsisya Shafira; Azhar, Gustika; Yadi, Hervi; Kurnia, Lisa; Nadia, Putri; Astaharie, Shinta Angelia; Adela, Syarifah Nur; Pratiwi, Wulan Iska; Zikrinnissa, Zikrinnissa
Jurnal Bakti Nusantara Vol. 2 No. 2 (2024): Jurnal Bakti Nusantara
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/jbn.v2i2.70

Abstract

Telah dilakukan sosialisasi bahaya konsumsi gula berlebihan dan dampaknya bagi kesehatan masyarakat di Kota Pekan Baru. Kegiatan yang melibatkan peserta berjumlah 60 orang dilakukan di Stadion Utama Riau. Metode yang digunakan dalam sosialisasi ini adalah demonstrasi dan diskusi serta pembagian leaflet kepada masyarakat. Pengukuran efektivitas kegiatan sosialisasi ini dilakukan dengan memberikan tes berbentuk kuisoner yang diberikan sebelum kegiatan sosialisasi sebagai tes awal (pretest) dan tes akhir setelah sosialisasi (post-test). Hasil yang diperoleh dari kegiatan ini adalah telah terjadi peningkatan pemahaman peserta tentang bahaya konsumsi gula berlebihan dan dampaknya bagi kesehatan setelah kegiatan dilaksanakan. Analisis sosiodemografi yang melihat kategori umur, jenis kelamin, tingkat pendidikan, status pekerjaan, dan penghasilan peserta menunjukkan bahwa kenaikan pengetahuan yang signifikan terjadi pada peserta yang berusia 17-25 tahun, peserta jenis kelamin perempuan, peserta yang berpendidikan tinggi, peserta yang bekerja, dan berpenghasilan tinggi. Pengetahun yang baik akan bahaya konsumsi gula berlebihan dan dampaknya bagi kesehatan masyarakat akan dapat membantu mengurangi jumlah kasus penyakit degeneratif yang semakin banyak terjadi.
IMPROVED SOLUBILITY NOVEL MULTICOMPONENT CRYSTALS OF FENOFIBRIC ACID-ACETYLSALISYLIC ACID Anggraini, Deni; Novita, Gressy; Wulandari, Intan
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1690

Abstract

Solubility is an important physicochemical property of active pharmaceutical ingredients. Poor water solubility of active pharmaceutical ingredients leads to low bioavailability; therefore, efforts are needed to improve the solubility of active pharmaceutical ingredients. The goal of this study was to prepare and characterize novel multicomponent crystals of fenofibric acid (FA) using acid acetylsalicylic (ACE) as a coformer and to evaluate the solubility enhancement when prepared for multicomponent crystal formation.  Solid characterization of the novel multicomponent crystals was performed using powder X-ray diffraction (XRD), differential scanning diffraction (DSC), Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), polarized microscopy, and solubility tests. Multicomponent crystals were prepared by the solvent drop grinding method using a few drops of an ethanol pro analyzer. The results showed that the solubility of multicomponent crystalline fenofibric acid was 4.7 times greater than that of pure fenofibric acid. Differential Scanning Calorimetry characterization results show the novel multicomponent crystals  with a sharp endothermic peak at 136,65 oC. The PXRD diffractograms show no new diffraction peaks and a decrease  in intensity. FT-IR spectroscopic analysis showed no new functional groups, and most of the transmittance peaks of the multicomponent crystals were superimposed between the peaks of fenofibric acid and acetylsalicylic acid. The novel multicomponent crystals fenofibric acid with acetylsalicylic acid as a coformer can improve the solubility of fenofibric acid  Keywords: Acetylsalicylic acid ; Fenofibric acid ; Multicomponent crystals ; Solubility  
Edukasi Penggunaan Tanaman Herbal Terhadap Penderita Diabetes di Desa Empat Balai, Kampar Rasyid, Wildan; Pratiwi, Wirahma Indah; Djohari, Meiriza; Anggraini, Deni; Mora, Enda; Almurdani, M.; Ikhtiarudin, Ihsan; Harpirabi, T.; Jasma, Jasma; Tami, Tami; Sukma, Sukma
Jurnal Medika: Medika Vol. 4 No. 3 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/w8yeem10

Abstract

Diabetes mellitus is a public health problem that continues to increase, especially in rural areas that have limited access to modern health services. The use of herbal plants as alternative therapy is increasingly receiving attention because of its abundant availability and relatively low cost. In order to increase public awareness of the importance of prevention and treatment, especially with herbal ingredients for this degenerative disease, there needs to be ongoing counseling, one of which is through community service. This community service activity aims to provide education on the use of herbal plants that have the potential to lower blood sugar levels to the people of Empat Balai Village, Kuok District, Kampar Regency. The activities include counseling, interactive discussions, and demonstrations of the use of local herbal plants such as insulin leaves (Costus igneus), Moringa leaves (Moringa oleifera), Belimbing Wuluh (Averrhoa bilimbi), Pare (Momordica charantia), sambiloto, and mahkota dewa. The research method uses a qualitative approach with counseling techniques and leaflets given to 50 respondents. The results of the study showed an increase in public knowledge or insight about the use of herbal plants for diabetes sufferers with significance (p <0.5). The results of this Community Service activity show the importance of educating the community about managing diabetes naturally and increasing interest in implementing the use of herbs as a treatment support. Therefore, further efforts need to be made to increase insight and prevention related to Diabetes Mellitus by using herbal plants holistically.
IMPROVED SOLUBILITY NOVEL MULTICOMPONENT CRYSTALS OF FENOFIBRIC ACID-ACETYLSALISYLIC ACID Anggraini, Deni; Novita, Gressy; Wulandari, Intan
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 1 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i1.1690

Abstract

Solubility is an important physicochemical property of active pharmaceutical ingredients. Poor water solubility of active pharmaceutical ingredients leads to low bioavailability; therefore, efforts are needed to improve the solubility of active pharmaceutical ingredients. The goal of this study was to prepare and characterize novel multicomponent crystals of fenofibric acid (FA) using acid acetylsalicylic (ACE) as a coformer and to evaluate the solubility enhancement when prepared for multicomponent crystal formation.  Solid characterization of the novel multicomponent crystals was performed using powder X-ray diffraction (XRD), differential scanning diffraction (DSC), Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), polarized microscopy, and solubility tests. Multicomponent crystals were prepared by the solvent drop grinding method using a few drops of an ethanol pro analyzer. The results showed that the solubility of multicomponent crystalline fenofibric acid was 4.7 times greater than that of pure fenofibric acid. Differential Scanning Calorimetry characterization results show the novel multicomponent crystals  with a sharp endothermic peak at 136,65 oC. The PXRD diffractograms show no new diffraction peaks and a decrease  in intensity. FT-IR spectroscopic analysis showed no new functional groups, and most of the transmittance peaks of the multicomponent crystals were superimposed between the peaks of fenofibric acid and acetylsalicylic acid. The novel multicomponent crystals fenofibric acid with acetylsalicylic acid as a coformer can improve the solubility of fenofibric acid  Keywords: Acetylsalicylic acid ; Fenofibric acid ; Multicomponent crystals ; Solubility