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All Journal Jurnal Penelitian Farmasi Indonesia Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Majalah Obat Tradisional Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Pharmacology and Clinical Pharmacy Research Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Manajemen Rekayasa (Journal of Engineering Management) Jurnal Medika: Medika Jurnal Bakti Nusantara Medical Sains : Jurnal Ilmiah Kefarmasian
Deni Anggraini
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Other

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Formulasi Sabun Cair dari Ekstrak Batang Nanas (Ananas comosus. L ) untuk Mengatasi Jamur Candida albicans Anggraini, Deni; Rahmides, Wiwik Sri; Malik, Masril
Jurnal Penelitian Farmasi Indonesia Vol 1, No 01 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

A study on antifungal effect of liquid soap formulation of extract of pineapple stem (Ananas comosus L) has been carried out towardsCandida albicans. Three different concentrations of extract 3; 5 and 7%, were formulated as liquid soap using TEA, stearic acid andglycerine as its soap bases. Several evaluations were examined on the liquid soap formulation including organoleptic examination, determinationof relative density, viscosity, foam test, pH test, and skin irritation test. While antifungal effect test of the obtained formulations was testedon PDA medium. The result revealed that extract of pineapple stem was successfully formulated and physically stable in liquid soap form.The antifungal effect test showed that formula with 7% concentration of extract demonstrated the strongest effect with 21.3 mm diameterof inhibition towards Candida albicans.
Formulasi Gel Antijerawat dari Ekstrak Etil Asetat Gambir Anggraini, Deni; Rahmawati, Noveri; Hafsah, Siti
Jurnal Penelitian Farmasi Indonesia Vol 1, No 2 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

The formulas of antiacne gel preparation of ethyl acetate extract of gambir have been formulated by using carbopol 940P as its bases. In thisstudy, five difference gel formulas F1, F2, F3, F4 and F5, were prepared with 0.5; 1; 2; 4 and 6% of concentration of extract, respectively.The result showed that organoleptic of al formulas was found unstable, while the appearance of gel F1 and F2 were homogeneous and stableat room temperature as well as cooling process. In addition, all formulas exhibited stable value in pH evaluation and did not irritate the skin.
Pembuatan dan Uji Sifat Fisikokimia Pati Beras Ketan Kampar yang Dipragelatinasi Lukman, Anita; Anggraini, Deni; Rahmawati, Noveri; Suhaeni, Nani
Jurnal Penelitian Farmasi Indonesia Vol 1, No 2 (2013)
Publisher : Jurnal Penelitian Farmasi Indonesia

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Abstract

Glutinous rice contains 99.7% of amilopectin. The amilopectin does not swell in cold water and it could retard the desintegration anddissolution of drug. Physical modification of glutinous rice by pregelatization can enhance the swelling power of starch in cold water. In thisstudy, glutinous rice used as sample was collected from three difference places which are kecamatan Air Tiris, Rumbio Jaya dan Salo kabupatenKampar, Riau province. Sample was subjected to pregelatization process manually as well as by using Spray Dryer. The result showed thatpregelatized glutinous rice starch gave the higher swelling power than glutinous rice. Glutinous rice from Rumbio Jaya showed the highestswelling power of 343.87%. This value indicated that it could be potential candidate as sustained release agent.
Physicochemical Properties of Phosphate Pregelatinized Musa balbisiana Starch as Pharmaceutical Excipient Anggraini, Deni; Lukman, Anita; Teruna, Hilwan Y.
Pharmacology and Clinical Pharmacy Research Vol 1, No 3
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (676.153 KB) | DOI: 10.15416/pcpr.v1i3.15398

Abstract

Starch is among the important pharmaceutical excipient, which is particularly used as filler in the tablet formulation and suspending agent. Starch from natural source has a potential to be developed as pharmaceutical excipient with comparable characteristics, including starch from Musa balbisiana (M. balbisiana). This study aimed to synthesize and evaluate physicochemical properties of phosphate pregelatinized M. balbisiana starch. We isolated the starch from M. balbisiana and performed pregelatinization. Since pregelatinized starch still could experience retrogradation which cause syneresis, chemical modification of pre-gelatinized starch was conducted using 5% of sodium tripolyphosphate at pH of 9-10. Physicochemical properties of phosphate pregelatinized starch were then investigated. It included the assessment of its organoleptic, pH, water content, particle size distribution, angle of repose, swelling power, amylose content, adsorbs isotherm, and particle analysis using Scanning Electron Microscope (SEM). Phosphate-pregelatinized M. balbisiana starch had low swelling power, better flow properties and viscosity. It can be used particularly in the formulation of slow released tablets and suspending agents in suspension formula.Keywords: pregelatinized starch, Musa balbisiana, psychochemical properties, excipients
Efektifitas Krim Papain Kasar Getah Buah Pepaya (Carica Papaya.L) yang Diolah Dengan Metode Freeze Drying Terhadap Penyembuhan Penebalan Kulit (Callus) Anggraini, Deni
Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Vol 6, No 1 (2020): Pharmauho
Publisher : Fakultas Farmasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/pharmauho.v6i1.10407

Abstract

Telah dilakukan penelitian uji efektivitas krim papain kasar getah buah papaya (Carica papaya L) yang diolah dengan metode freeze drying terhadap penyembuhan penebalan kulit (Callus). Penelitian ini bertujuan untuk mengetahui efektivitas proteolitik  dari papain kasar dalam penyembuhan Callus yang diolah dengan metode freeze drying. Formula dibuat dengan memvariasikan konsentrasi papain kasar getah buah papaya (Carica papaya L) 10%, 15%, dan 20% dengan pemilihan tipe krim A/M. Evaluasi sediaan krim yang dilakukan meliputi organoleptis, homogenitas, pH, stabilitas suhu, daya tercuci krim, daya menyebar dan uji iritasi kulit. Dari hasil penelitian diperoleh papain kasar getah buah papaya (Carica papaya L) dapat diformulasi dalam bentuk krim untuk penyembuhan penebalan kulit (Callus). Hasil pengurangan diameter Callus pada konsentrasi 10% yaitu A 0,65 cm, B 0,65 cm, C 0,35 cm, konsentrasi 15% yaitu A 0,4 cm, B 0,6 cm, C 0,6 cm, dan konsentrasi 20% yaitu A 1,25 cm, B 0,5 cm, C 0,7 cm. Krim papain kasar getah buah papaya (Carica papaya L) konsentrasi 20% dibandingkan dengan kontrol positif krim asam salisilat 20% belum memberikan efektivitas cukup baik.
FORMULASI KRIM SERBUK GETAH BUAH PEPAYA (Carica papaya L) SEBAGAI ANTI JERAWAT Deni Anggraini; Masril Malik; Maria Susiladewi
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Peranan dan Kontribusi Herbal dalam Terapi Penyakit Degeneratif"
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (51.038 KB) | DOI: 10.31942/jiffk.v0i0.378

Abstract

Telah dilakukan penelitian tentang formulasi krim serbuk getah buah pepaya (Carica papaya) sebagai anti jerawat. Formulanya dibuat dengan memvariasikan konsentrasi serbuk getah buah papaya dalam bentuk sediaan krim. Evaluasi sediaan krim dilakukan terhadap organoleptis, homogenitas, pH, stabilitas fisik, pemeriksaan distribusi ukuran partikel, iritasi kulit, daya tercuci, dan daya menyebar. Uji efektifitas krim dilakukan pada sukarelawan/panelis dengan cara mengoleskan tipis sediaan krim pada wajah yang terkena jerawat. Dari hasil penelitian diperoleh bahwa krim dengan konsentrasi 4% dengan tipe minyak-air M/A memberikan hasil yang lebih efektif dibandingkan dengan konsentrasi 2% dan 3%.   Kata kunci : Carica papaya, krim, jerawat
PEMANFAATAN PATI PISANG KEPOK (Musa balbisiana L.) TERPRAGELATINASI POSPAT SEBAGAI SUSPENDING AGENT SUSPENSI KLORAMFENIKOL Deni Anggraini; Anita Lukman; Delvi
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1321

Abstract

Kepok banana (Musa balbisiana L.) natural starch easily undergoes syneresis due to starch retrogradation which can reduce the stability and viscosity of a suspension preparation, so it is necessary to modify starch to overcome this problem. One of the starch modification technologies is chemical modification with crosslinks. Utilization of kepok banana phosphate pregelatinated starch (Musa balbisiana L.) as a suspending agent in chloramphenicol palmitate suspension has been carried out and evaluated for its physicochemical properties and stability during storage. The method of making the suspension is the dispersion method. F1 used 5% kepok banana phosphate pregelatinated starch, F2 (7.5%) and F3 (10%). The results showed that the best formula was F3 with observations of organoleptic, viscosity and flow properties, degree of sedimentation, redispersibility, density, and pH which met the requirements during 4 weeks of storage.
Formulation of Microemulsion of Cayenne Pepper (Capsicum Frutescens L.) Ethanol Extract and Hair Growth Activity Test Anggraini, Deni; Sandi, Nofri Hendri; Djohari, Meiriza
Majalah Obat Tradisional Vol 29, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.87206

Abstract

Cayenne pepper contains capsaicin, which exhibits properties that promote hair growth. Microemulsion is an oil and water dispersion system with a particle size of 10-200 nm which can be used topically as a drug delivery system through the scalp to stimulate hair growth. The microemulsion was made with olive oil and tween 80 as surfactants and stirred using a magnetic stirrer at 1000 rpm for 3 minutes. The ethanol extract of cayenne pepper was prepared in microemulsions at three different concentrations: 0.1%, 0.2%, and 0.3%. Microemulsion tests included organoleptic tests, specific gravity, pH, viscosity, freezing and thawing stability tests, and hair growth activity tests on rabbits. The results showed that the microemulsion of cayenne pepper ethanol extract at concentrations of 0.1%, 0.2%, and 0.3% was quite stable with a clear appearance and a particle size ranging from 27.7 nm to 167.8 nm. The microemulsion of cayenne pepper ethanol extract at a concentration of 0.2% was the most effective in enhancing hair growth, achieving a hair growth length of 1.27 over a 30-day period. A two-way ANOVA statistical test showed that the hair length of rabbits using microemulsion was significantly different from the hair length of negative control animals at p<0.05.
PENTINGNYA NUTRISI DI 1000 HARI PERTAMA KEHIDUPAN UNTUK MENCEGAH STUNTING PADA ANAK DI DESA KUAPAN Anggraini, Deni; Sinata, Novia; Agistia, Nesa; Almurdani, M.; Indriana, Annisa Chika Ayu; Melanie, Claudy Friesta; Azli, Echa Saskia; Suwinda, Elia; Mulyani, Fitri; Wulandari, Lydia Tri; Audina, Mia; Nabela, Nabela; Azizah, Nur Rahmi; Suhada, Zikra
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 6 (2023): Volume 4 Nomor 6 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i6.22531

Abstract

Masalah balita pendek (stunting) merupakan salah satu permasalahan gizi yang menjadi fokus di negara-negara berkembang, seperti Indonesia. Stunting merupakan bentuk kegagalan pertumbuhan (growth faltering) akibat akumulasi ketidakcukupan nutrisi yang berlangsung lama mulai dari kehamilan sampai usia 24 bulan. Keadaan ini diperparah dengan tidak terimbanginya kejar tumbuh (catch up growth) yang memadai. Di Indonesia, berdasarkan Riskesdas 2013 terjadi peningkatan anak stunting dari 36,8% pada tahun 2010 menjadi 37,2% pada tahun 2013. Selama 20 tahun terakhir, penanganan masalah stunting sangat lambat. Secara global, persentase anak-anak yang terhambat pertumbuhannya menurun hanya 0,6 persen per tahun sejak tahun 1990. WHO mengusulkan target global penurunan kejadian stunting pada anak dibawah usia lima tahun sebesar 40 % pada tahun 2025, namun diprediksikan hanya 15-36 negara yang memenuhi target tersebut. Kegiatan pengabdian ini dilakukan dengan tujuan untuk melihat pengetahuan masyarakat tentang stunting dan mengedukasi cara mencegah terjadinya stunting pada anak dimasa pertumbuhan. Untuk mencapai tujuam tersebut dilakukan beberapa kegiatan yaitu pelaksanaan pre-test, penyuluhan, dan post-test terkait stunting dan cara pencegahan stunting. Kegiatan ini dilakukan terhadap 50 responden di Desa Kuapan Kab. Kampar. Berdasarkan hasil analisis Bivariat diketahui bahwa pemberian perlakuan berupa edukasi masyarakat (pre test) mengenai stunting menunjukkan adanya pengaruh signifikan dibandingkan (Post Test) dengan ada kuisioner dengan pertanyaan yang sama dengan skor (pre test) dari 50 orang yaitu 30 orang 60%, 17 orang 34% dan 3 orang 6% dan (post test) dari 50 orang 100%.
PENGARUH PEMBANGUNAN JEMBATAN BAHTERAMAS TELUK KENDARI TERHADAP KELANCARAN DISTRIBUSI BARANG PT. MITRA INTERTRANS FORWARDING (MIF) Anggraini, Deni; Kadir, Abdul; Putra, Adris Ade
Jurnal Manajemen Rekayasa (Journal of Engineering Management) Vol 5, No 2 (2023): Oktober Tahun 2023
Publisher : Pascasarjana Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/jmr.v5i2.47445

Abstract

Tujuan penelitian ini untuk : (1) Menganalisis pengaruh positif dan signifikan distribusi terhadap Kepuasan pengguna PT Mitra Intertrans Forwarding (MIF) setelah adanya jembatan Bahteramas (2) Menganalisis pengaruh positif dan signifikan transportasi terhadap Kepuasan pengguna PT Mitra Intertrans Forwarding (MIF) setelah adanya jembatan Bahteramas (3) Menganalisis distribusi dan transportasi secara bersama-sama berpengaruh positif dan signifikan terhadap Kepuasan pengguna PT Mitra Intertrans Forwarding (MIF) setelah adanya jembatan Bahteramas. Penelitian ini bersifat deskriptif kuantitatif dengan jumlah populasi penelitian sebanyak 20 orang sehingga metode penentuan sampel menggunakan tehnik sampel jenuh yaitu menjadikan semua anggota populasi menjadi sampel. Variabel penelitian adalah distribusi (X1) dan tranportasi (X2) sebagai variabel bebas serta kepuasan pengguna adalah variabel terikat (Y). Analisis yang digunakan adalah analisis regresi berganda. Hasil penelitian menunjukkan bahwa Distribusi berpengaruh positif dan signifikan terhadap kepuasan pengguna pada taraf α = 5%. Kesimpulan ini mengandung makna bahwa distribusi yang sangat baik memiliki arah yang positif dan nyata dalam meningkatkan kepuasan pengguna setelah adanya jembatan Bahteramas, Transportasi berpengaruh positif dan signifikan terhadap kepuasan pengguna pada taraf α = 5%. Kesimpulan ini mengandung makna bahwa transportasi yang sangat baik memiliki arah yang positif dan nyata dalam meningkatkan kepuasan pengguna setelah adanya jembatan Bahteramas dan Distribusi dan transportasi berpengaruh positif dan signifikan secara bersama-sama terhadap kepuasan pengguna pada taraf α = 5%. Kesimpulan diatas dapat dimaknai bahwa distribusi dan transportasi memiliki arah yang positif dan nyata dalam meningkatkan kepuasan pengguna. melalui distribusi yang efektif dalam mengirimkan dan meyalurkan barang ke pengguna setelah adanya jembatan Bahteramas. Kata Kunci: Distribusi, transportasi dan kepuasan pengguna
Co-Authors Abdul Kadir Adela, Syarifah Nur Adris Ade Putra Agistia, Nesa Al-Fadillah, Annsisya Shafira Anita Lukman Anita Lukman Astaharie, Shinta Angelia Azhar, Gustika Azizah, Nur Rahmi Azli, Echa Saskia Delvi Enda Mora Fitri Mulyani, Fitri Gressy Novita Harpirabi, T. Ihsan Ikhtiarudin Indriana, Annisa Chika Ayu Jasma, Jasma Kurnia, Lisa M Almurdani Maria Susiladewi Masril Malik Meiriza Djohari, Meiriza Melanie, Claudy Friesta Mia Audina, Mia Nabela, Nabela Nadia, Putri Nani Suhaeni Nofri Hendri Sandi Noveri Rahmawati Pratiwi, Wirahma Indah Pratiwi, Wulan Iska Rasyid, Wildan Sandra, Alya Dwi Sinata, Novia Siti Hafsah Suhada, Zikra Sukma, Sukma Suwinda, Elia Tami, Tami Teruna, Hilwan Y. Wiwik Sri Rahmides Wulandari, Intan Wulandari, Lydia Tri Yadi, Hervi Zikrinnissa, Zikrinnissa