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Nicotine-free vape liquids containing essential oils of peppermint, lavender, and tangerine: safety and efficacy profiles Prasetya, Rahmad Aji; Arifiyana, Djamilah; Syulthoni, Zain Budi
Pharmaciana Vol. 14 No. 3 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i3.30005

Abstract

Despite low nicotine levels, cigarettes and vape liquids can cause addiction, which makes quitting smoking difficult owing to withdrawal syndrome. Hence, we created a nicotine-free liquid vape using essential oils (EOs) like peppermint (Mentha piperita), lavender (Lavandula latifolia), and tangerine (Citrus reticulata) to substitute the nicotine in inducing relaxation without addiction. Thus, this study aimed to examine (1) the safety profile of this nicotine-free liquid vape by observing chemical characteristics using gas chromatography-mass spectrometry (GC-MS) and (2) its efficacy in reducing short-term anxiety in healthy volunteers who had previously used nicotine vape. The most complicated vape liquid formula (F4), containing propylene glycol, vegetable glycerin, with those three EOs, was injected into GC-MS, and the mass spectra were compared to the Wiley mass spectral library to identify the compound name. For the efficacy test, subjects who met inclusion criteria and fulfilled informed consent were randomly assigned to five groups (four groups received test liquids formula (F1-F4) while one group received placebo). Before and after using the vape liquid, subjects were asked to complete the State-Trait Anxiety Inventory (STAI) questionnaire to assess its anxiety-reduction effects. The result showed that nicotine-free vape liquids containing three EOs did not show any foreign substances that had never been encountered before, which means our product is safer than nicotine-containing vape liquids. This safety was also supported by all study subjects who did not report any adverse effects. The efficacy test showed that subjects who used vape liquids with essential oils (F1-F4) experienced a significant decrease in heart rate and systolic blood pressure. At the same time, 50% had a lower post-test STAI score, indicating a decrease in anxiety, although it was not statistically significant.
Adsorption Performance of Turmeric as Biosorbent for Free Fatty Acid Removal in Used Cooking Oil Devianti, Vika Ayu; Arifiyana, Djamilah; A’yuni, Qurrota
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.10201

Abstract

Repeated use of cooking oil produces hazardous compounds such as free fatty acids, carbonyls, and peroxides. This study aims to examine the effectiveness of turmeric as a bio-adsorbent in reducing free fatty acid levels, peroxide numbers, and water content in used cooking oil, and determine the appropriate adsorption isotherm model. Turmeric is one of the biopharmaceutical plants whose availability is quite abundant in Indonesia. Adsorption was carried out with variations in adsorbent mass and contact time. The result showed that turmeric is effective in reducing free fatty acid levels, peroxide value, and water content with adsorption efficiency of up to 54.02, 48.78, and 42.89%, respectively. The adsorption isotherm analysis suggested that the adsorption of free fatty acids followed the Freundlich model rather than the Langmuir model. This study reveals that turmeric has the potential to be a viable bio-adsorbent for enhancing the quality of used cooking oil.