Elli Arsita
Department of Internal Medicine, Faculty of Medicine, University of Indonesia Dr. Cipto Mangunkusumo General National Hospital, Jakarta

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Journal : Jurnal MedScientiae

Relations Between Stress Level and the Occurrence of Constipation to Medical Students Arsita, Elli; Wician, Fendra; Mamudi, Chrispian Oktafbipian; Mahonny, Glorie Libertikha
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3069

Abstract

Stress can be experienced by anyone. The number of events is increasing every year. This isevidenced from the results of Basic Health Research in 2013 and 2018, namely an increase in theprevalence of mental emotional disorders in Indonesian population aged ≥ 15 years from 6percent to 9.8 percent. Stress can have a negative impact on the human body both physically andpsychologically. One of the effects of stress on the body is constipation. Unfortunately not muchliterature discusses stress and constipation in more detail. This study aims to determine whetherthere is a relationship between stress levels and constipation in the seventh semester students ofthe 2016 Faculty of Medicine and Health Sciences at Ukrida. This research uses analytic studymethod with cross-sectional approach. Sampling is done by consecutive sampling method. Thestudy was conducted in December 2019 at the Ukrida’s medical campus. 150 out of 206 studentsof 2016 from Ukrida Faculty of Medicine and Health Sciences who are in their seventh semester,are included in the inclusion criteria. The research material is primary data in the form of aConstipation Scoring System questionnaire and Perceived Stress Scale. The results showed arelationship between stress levels and constipation. This was obtained from the Chi Square testcalculation which was calculated using the SPSS computer program, where the p value was 0.01(p <0.05).
Peran Vitamin D Dalam Menurunkan Risiko Penyakit Kardiovaskular Lim, Audi; Arsita, Elli
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3138

Abstract

Cardiovascular disease is the main cause of death in the world. Vitamin D is known to have an influence on the cardiovascular system through the role of the vitamin D receptor (VDR) expressed by vascular endothelial smooth muscle cells and cardiomyocytes. This literature review analyze the role of vitamin D in relation to the risk of cardiovascular disease through a study of scientific articles from Google Scholar and Pubmed. The results showed that patients with severe vitamin D deficiency (serum 25(OH) levels <10 ng/ml) had an increased risk of myocardial infarction with OR 4.5 (95% CI 2.2–9.2), and increased risk of PAD with OR 3.872 (95% CI: 1.168–12.841), while vitamin D deficiency (serum 25(OH) levels <20 ng/ml) caused an increased risk of acute ischemic stroke with OR 16.64 (95% CI: 5 .66–42.92; p < 0.001). Administration of 1x 600,000IU or 2x300,000IU intramuscular vitamin D in coronary heart disease patients with deficiency showed significant reduction in the inflammatory marker hsCRP and improved endothelial function. However, in clinical trials, significant but inconsistent results were obtained due to differences in the cut off value for Vit D deficiency, diversity in age, gender, variations in polymorphisms, smoking habits, physical activity, body weight, and various comorbidities suffered by patients.
Perbandingan Efektivitas Injeksi Agen-Agen Anti-Vegf pada Pengobatan Age-Related Macular Degeneration Nahak, Petronela Bhoko; Arsita, Elli; Wastitiamurti, Ritsia Anindita
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3143

Abstract

Age-related macular degeneration (AMD) is one of the leading causes of blindness in people >60 years of age in developed countries. The pathogenesis of neovascular AMD involves increased choroidal vascular permeability, leading to hypoxia and the production of pro-inflammatory and pro-angiogenic factors, particularly vascular endothelial growth factor (VEGF). Treatment of neovascular AMD involves anti-VEGF therapy, which inhibits abnormal blood vessel growth. Numerous studies have demonstrated the effectivity and side effects of each Anti-VEGF agent. Based on this background, the author is interested in conducting a literature review that summarizes the effectivity and side effects of each Anti-VEGF agent. The method used was Literature Review. Journals were collected using GoogleScholar or Google Scholar, PubMed and Proquest within the last 10 years. A total of 10 journals that met the inclusion-exclusion criteria were reviewed and tested for eligibility with the Ottawa score. The results of this literature review showed that anti-VEGF agents including bevacizumab, ranibizumab, aflibercept, pegaptanib sodium, brolucizumab and abicipar pegol have been shown to be equally effective in improving vision and maintaining stable vision in neovascular AMD patients. However, these anti-VEGF treatments can also cause side effects such as intraocular inflammation, increased intraocular pressure and vascular problems.
Infection in Burn Wound Patient Septrilla, Gladys; Arsita, Elli
Jurnal MedScientiae Vol. 3 No. 3 (2024): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3494

Abstract

Infection is a major cause of increased morbidity and mortality in burns. It is known that about 67% of wound swab cultures are positive for bacterial infection. Burn infection occurs when the skin as the first line of defense is disturbed so that it becomes a good ground for bacterial growth. Literature review by searching through electronic databases such as PubMed, ProQuest, and Google Scholar with the keywords. Bacteria that are often found to cause burn infection are Pseudomonas aeruginosa (24.95%), Staphylococcus aureus (24.05%), Acinetobacter sp (17.09%), and Klebsiella sp (15.19%). Factors causing infection are age, degree of burn, hospitalization of more than 10 days, drug resistance, and inadequate wound management. The most common pathogen causing burn infection is Pseudomonas aeruginosa, because it can grow in a humid environment. The proper use of definitive antibiotics to fight infection is very important. Piperacillin-Tazobactam, Imipenem, Colistin, and Polymyxin B have high sensitivity to gram-negative bacteria, while Vancomycin and Linezolid are effective against gram-positive bacteria and also in treating MRSA.
Perbandingan Efektivitas Penurunan Berat Badan pada Pasien Gastric Bypass & Gastric Sleeve RS EMC Alam Sutera 2021-2023 Agnes Caitlyn Kapito; Suhuyanly, Nella; Arsita, Elli
Jurnal MedScientiae Vol. 4 No. 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3609

Abstract

Background: Obesity is a growing global health issue. According to WHO data from 2022, one in eight people worldwide lives with obesity, and 21.8% of the adult population in Indonesia suffers from obesity. Bariatric surgery approaches, typically gastric sleeve and gastric bypass have become one of the options to address this problem. Objective: This study aims to compare the efficacy of weight loss in patients undergoing bariatric surgery at EMC Alam Sutera Hospital between 2021 and 2023. Methods: This research is an analytical descriptive study with a retrospective cohort approach. The sample size was determined using purposive sampling technique, with a total of 70 samples. Data were obtained from medical records at EMC Alam Sutera Hospital from 2021 to 2023. Results: Out of 70 patients with an average age of 37.1 years, 88.6% were female and 11.4% were male. No significant differences were found in the variables (p > 0.05). The average weight loss for both surgeries was 5.9 kg, with no statistically significant difference. A higher correlation was observed for gastric sleeve (0.996) compared to gastric bypass (0.985). Conclusion: It can be concluded that both gastric bypass and gastric sleeve are proven effective in reducing weight. Both methods show strong correlations, although gastric sleeve has a slightly higher correlation. There is no significant difference in effectiveness between the two methods, with p > 0.05 for all measured parameters.
Prediktor Mortalitas Pasien Sindrom Koroner Akut di Rumah Sakit X Jakarta Periode September 2023-2024 Rante Tiku, Ristha Monica; Arsita, Elli; Oktavia, Eva
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3721

Abstract

Acute coronary syndrome (ACS) is the leading cause of death from heart disease worldwide. Several studies have identified risk factors that increase mortality among ACS patients, including advanced age, type 2 diabetes mellitus, and chronic kidney disease. This study aims to evaluate the association between these risk factors and mortality in ACS patients at Hospital X Jakarta between September 2023 and September 2024. Contains This study used a retrospective cohort design with analysis of medical record data of patients with ACS. Statistical analysis was performed using chi-squared and Fisher's exact tests to determine the association of age, type 2 diabetes mellitus, and chronic kidney disease with mortality in patients with ACS. Contains A total of 84 patients with a mean age of 59.49 years met the study criteria. The majority of patients had NSTEMI (61.9%) and 56% had type 2 diabetes mellitus. Mortality occurred in 4.8% of the patients. The results of the analysis showed that advanced age (≥60 years) was significantly associated with mortality in SCA patients (p=0.047; RR=4.50). Chronic kidney disease was also significantly associated with mortality (p=0.011; RR=8.16). However, type 2 diabetes mellitus did not show a significant association with mortality (p=0.092). Advanced age and chronic kidney disease were significant predictors of mortality in patients with ACS, whereas type 2 diabetes mellitus was not significantly associated with mortality.