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Journal : JURNAL GIZI INDONESIA

Pengaruh variasi pemberian Snack bar ubi jalar kedelai hitam terhadap Kadar Superoksida Dismutase (SOD) darah Ayustaningwarno, Fitriyono; Sabuluntika, Novita
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.591 KB) | DOI: 10.14710/jgi.3.1.109-114

Abstract

Background: Snack bar from sweet potatoes and black soybeans is low GI, fat and calorie snack which haveantioxidant content, such as β-carotene, anthocyanin, isoflavone, and antioxidant activity, so can be an alternativesnack for patients with DM type 2. Antioxidants intake can prevent the oxidative stress that lead micro- and macrovascularcomplications in DM type 2. Antioxidant intake may preserve endogen antioxidant capacity, which is can bedetermined by analyzing SOD concentration.Objective: analyze effect variety of Snack bar from sweet potatoes and black soybeans consume to SOD concentration.Methods: experimental post-pretest research used 3 varieties of sweet potato’s color (red, yellow, and purple)interventions. SOD concentration was analyzed by colorimetric. Statistic data was analyzed by dependent t-test andOne Way Anova.Results: No different between groups interventions Snack bar from purple, yellow or red sweet potatoes (p=0,122).Group with snack bar from purple sweet potatoes intervention has lowest SOD decreasing percentage among otherintervention groups.Conclusion: Consume snack bar form purple sweet potatoes and black soybeans can preserve SOD concentrationbetter than consume snack bar form yellow or red sweet potatoes and black soybeans
Effect of leunca (Solanum nigrum) on inflammatory status in rats induced by high-fat and high-sucrose diet Gunawan, Sekar Ayu Putri; Muis, Siti Fatimah; Anjani, Gemala; Noer, Etika Ratna; Ayustaningwarno, Fitriyono
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.99-104

Abstract

Background: Consumption of foods that are high in calories over a long period of time is a cause of obesity and can increase proinflammatory cytokines. Leunca fruit contains various phytochemicals that act as anti-inflammatory, antioxidant, and antiobesity but not many people utilize leunca fruit as daily food.Objective: To analyze the effect of leunca fruit on TNF-α and IL-6 levels in rats induced by high fat and sucrose diet (HFSD).Methods: The research design was Randomized Post Test Only Control Group Design. The sample was 30 male Sparague Dawley rats and divided into 5 groups, namely group K1 which was given standard feed, group K2 which was induced by HFSD, group P1 which was induced by HFSD and leunca 0.8g/200gBW, group P2 which was induced by HFSD and leunca 1.6g/200gBW, and group P3 which was induced by HFSD and leunca 2.4g/200gBW. The research was conducted at the Nutrition Laboratory of the Center for Food and Nutrition Studies of Gadjah Mada University (PSPG PAU UGM) Yogyakarta in January-March 2024. Testing TNF-α and IL-6 levels through rat blood serum using the ELISA method. Data were analyzed by ANOVA and Post Hoc test.Results: There was a significant difference in TNF-α and IL-6 levels between experimental groups (p=0.00). The levels of TNF-α and IL-6 in the P1, P2, and P3 groups that received HFSD + leunca were lower than in the K2 group that received HFSD only.Conclusion: Leunca fruit can reduce proinflammatory cytokine levels (TNF-α and IL-6) in HFSD-induced rats.