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All Journal Dentika Dental Journal Pro-Life Jurnal Pengabdian UntukMu NegeRI Best Journal (Biology Education, Sains and Technology) Journal of Functional Food and Nutraceutical Journal of Pharmaceutical and Health Research International Journal Of Science, Technology & Management (IJSTM) Jurnal Sains dan Teknologi Herbal Medicine Journal
Denny Satria
Department Of Pharmaceutical Biology, Faculty Of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Veterinary

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Immunostimulant Effect Test Of Curcuminoid Extract From Turmeric Rhizome (Curcuma Domestica Val.) In VCO On Rats Induced Cyclophosphamide Againts An Increasing Total Leukocytes And Leukocyte Differential Damayanti Damayanti; Yuandani Yuandani; Denny Satria
International Journal of Science, Technology & Management Vol. 4 No. 4 (2023): July 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i4.852

Abstract

Turmeric (Curcuma domestica Val.) is a traditional Indonesian plant that has many benefits. Curcuminoids are turmeric compounds known to have effects as immunomodulators and have been proven in several in vivo tests. Immunosuppressive drugs such as cyclophosphamide are widely given to improve clinical symptoms in autoimmune patients and cancer treatment which can cause susceptibility to infection.Therefore,this study aimed to determine the immunostimulating effect of curcuminoid extract from turmeric rhizome on cyclophosphamide-induced white rats. Proof of the immunostimulating effect of curcuminoid extracts was by testing the total leukocytes and leukocytesdifferential. The test results showed that curcuminoid extracts of 1 mL, 0.5 mL, and 0.25 mL increased total leukocytes and leukocyte differential (lymphocytes, neutrophils, monocytes, basophils, eosinophils) with a significant difference (p<0.05) to the Na group CMC 0.5% as a negative control. Therefore, curcuminoid extract had the potential to have an effect as an immunostimulant. The test results showed that curcuminoid extracts of 1 mL, 0.5 mL, and 0.25 mL increased total leukocytes and leukocyte differential (lymphocytes, neutrophils, monocytes, basophils, eosinophils) with a significant difference (p<0.05) to the Na group CMC 0.5% as a negative control. Therefore, curcuminoid extract had the potential to have an effect as an immunostimulant.
A Review on The Benefits of Probiotics as Fermented Food against Several Diseases Nasri, Nasri; Silalahi, Jansen; Kaban, Vera Estefania; Satria, Denny
Journal Akademik Universitas Swiss German Vol 5. No. 1 (Aug 2023)
Publisher : Swiss German University & Perhimpunan Penggiat Pangan Fungsional dan Nutrasetikal Indonesia (P3FNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33555/jffn.v5i1.110

Abstract

Fermentation is a natural process when microorganisms such as yeast and bacteria convert carbohydrates such as starch and sugar into alcohol or acid. Some fermented products from microorganisms can be processed into foods that can be consumed and provide good health effects for the body. Fermented foods such as kefir, tempeh, natto, and kimchi are foods that produce probiotic bacteria, which are good bacteria that have a beneficial effect on the host when consumed in sufficient quantities (about 108–1011 CFU/mL). If probiotics are consumed in combination with prebiotics, they will have a synergistic effect called "synbiotics" and will increase the benefits of probiotics. Several in vitro, in vivo, and clinical studies have shown that probiotics can help with diseases like diarrhea, high cholesterol, diabetes, colon cancer, and dyslipidemia
Co-Authors Avi Syafitri Cintya, Henni Damayanti Damayanti Effendy De Lux Putra, Effendy De Lux Hari Purnomo Hariyadi Dharmawan Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Henni Cintya Jansen Silalahi Kasta Gurning M. Fauzan Lubis Mahatir Muhammad Muhammad Fauzan Lubis Nasri N Nasri Nasri Nasri Nasri Olivia Avriyanti Hanafiah Panal Sitorus Rosidah, Rosidah Syukur Berkat Waruwu Urip Harahap Vera Estefania Kaban Yuandani Ziza Putri Aisyia Fauzi Zulmai Rani