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RESISTENSI INSULIN TERKAIT OBESITAS: MEKANISME ENDOKRIN DAN INTRINSIK SEL Mira Dewi
Jurnal Gizi dan Pangan Vol. 2 No. 2 (2007)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (72.482 KB) | DOI: 10.25182/jgp.2007.2.2.49-54

Abstract

The number of obese individuals worldwide has reached 2.1 billion and this will lead to explosion of obesity-related morbidity and mortality. Obese individuals will develop re­sistance to celluler action of insulin. The obesity related insulin resistance is the major risk factor of cardiovascular diseases and Type 2 Diabetes Mellitus, the disease which number has reached epidemic proportion. The association between obesity and insulin resistance seem to be cause and effect relation because studies on human and animal has indicated that the increase or decrease of body weight correlates with insulin sensitivity.  Among of many mechanisms proposed, the most often proposed mechanisms are endocrine and cell in­trinsik mechanism. The increase of fatty acid plasma concentration, dysregulation of adi­pokines and ectopic fat storage are proposed to be the endocrin mechanism that lead to obesity related insulin resistance while oxidative stress and mitochondria dysfunction are the cell intrinsic mechanisms that play role to the disease. Understanding the molecular mechanisms of obesity related insulin resistance will provide valuable information to search for interventions that help to prevent or treat Type 2 Diabetes Mellitus and cardiovascular diseases and its related pathologies.
POLA AKTIVITAS, KONSUMSI PANGAN, STATUS GIZI DAN KESEHATAN ANAK JALANAN DI KOTA BANDUNG Nur'aini Nur'aini; Mira Dewi
Jurnal Gizi dan Pangan Vol. 4 No. 2 (2009)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.902 KB) | DOI: 10.25182/jgp.2009.4.2.100-108

Abstract

The objective of the research was to analyze activity pattern, dietary consumption, nutritional status and health of street children in Bandung. Cross sectional design was used in this study to elaborate activity pattern, food consumption, nutritional status and health of street children in Bandung. Samples of street children was recruited by purposive sampling from eight NGOs in Bandung with following criterias: 1) 5-18 years old 2) spend time on the street at least four hours a day 3) work for living on the street, commonly as singers, beggars, shoe-polisher, porters etc. The result showed that most of the street children worked as singers, spend 4-8 hours a day and 4-6 days a week. The average energy and protein adequacy level of street children was in light deficit category, iron and vitamin Cwere in low category and vitamin A was in sufficient category. Almost all of the street children had normal nutritional and health status and good personal hygiene. There was no correlation between activity and duration of street children with nutrition adequacy level. There was no correlation between personal hygiene and nutritional status with health status.
INTERVENSI ISOFLAVON KEDELAI TIDAK BERPENGARUH TERHADAP STATUS INFLAMASI DAN IMUNITAS PADA REMAJA DENGAN KEGEMUKAN Mira Dewi; Ali Khomsan; Dadang Sukandar
Jurnal Gizi dan Pangan Vol. 5 No. 1 (2010)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.396 KB) | DOI: 10.25182/jgp.2010.5.1.1-5

Abstract

Overweight/obesity is a condition that has been proven to be interrelated with chronic inflammation and compromised immune system due to disregulation of adipocytokine. The aim of the present study was to evaluate the effect of soy isoflavone on the markers of inflammation and immunity of overweight or obese teenagers. Eighteen overweight or obese teenagers, 9 boys and 9 girls each sex were randomized to one of three  intervention groups; 0 ml, 150 ml and 300 ml soy milk, equal to 0 g, 25 g and 50 mg isoflavone everyday for 30 days. The data collected were food consumption, plasma isoflavone concentration, plasma IL6 as indicator of inflammation, and lymphocyte and NK cell count as indicator of immunity. The study showed that nutrient intake of samples were still relatively low. The soy milk intervention significantly increased plasma isoflavone concentration, but not significantly had contribution to the plasma IL6 concentration and lymphocyte and NK cell count. Several kind of food consumed by samples had contribution to the plasma isoflavone concentration, and lymphocyte count. Based on the results, it was suggested that soy isoflavone intervention does not affect the inflammation status and immunity of overweight/obese teenagers.
EFEKTIVITAS PEMBERIAN CGF 40% DALAM MEMPERCEPAT PENINGKATAN TROMBOSIT PADA PENDERITA DEMAM BERDARAH DENGUE Adi Teruna Effendi; M Sediono; HS Suksmono; B Erwanto; Yekti Hartati Effendi; Mira Dewi; Darwin Karyadi
Jurnal Gizi dan Pangan Vol. 5 No. 3 (2010)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.694 KB) | DOI: 10.25182/jgp.2010.5.3.130-138

Abstract

Aim of this study was to evaluate the effectiveness of CGF 40% in hastening the recuperation, as indicated by reduced length of hospital stay, improvement in clinical status, increase in platelets, and reduction in the hemoconcentration. The study group comprised of 84 consecutive DHF patients, 42 male and 42 female subjects, who were randomized into the control group receiving the WHO standard therapy and the intervention group receiving CGF 40% and the standard therapy. Hemoglobin, hematocrite and thrombocyte counts were taken daily until the subjects were free of the symptoms and signs of DHF, and the thrombocyte count read >100.000. The results were analyzed statistically, student t test and quadratic regression, using SPSS 16 software. The average length of recuperation time in the intervention and control groups were 2.76 days and 4.43 days respectively (p=0.000). Recuperation times of subjects with thrombocyte counts <50,000 and >50,000 of the intervention group (3,09 and 2,37 days) and the control group (4,2 and 4,5 days) were different significantly (p=0.016 and 0.000). When analized specifically in the treatment group, the recuperation time of those with thrombocyte counts <50,000U (2.37 days) did not differ to those with >50,000 (3.09 days) with p=0.112. Using quadratic regression, the increase in thrombocytes, reduction in hemoglobin concentrations and hematocrite were faster in the intervention group when compared to the control group, with R2 almost reaching 1. The study disclosed that administration of CGF 40% could reduce the recuperation time and improved the hemoconcentration, which presumably demonstrated the concept of regenerative medicine as indicated by the repairmen of vascular permeability.
NUTRIENTS INTAKE AND NUTRITIONAL STATUS OF STREET CHILDREN IN BANDUNG Rita Patriasih; Isma Widiaty; Mira Dewi; Dadang Sukandar
Jurnal Gizi dan Pangan Vol. 5 No. 3 (2010)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.465 KB) | DOI: 10.25182/jgp.2010.5.3.178-184

Abstract

The objectives of this research were to analyze food habits and nutrients intake, and health and nutritional status of street children. The research was carried out in the City of Bandung, West Java; Indonesia. A sample of 324 street children was selected randomly. The sample consisted of 232 boys and 92 girls. The data obtained from questionnaires. Means, standard deviation, frequency and proportion were calculated with a combination of software applications:  Microsoft Excel and Statistical Analysis System. The result showed the level of consumption adequacy did not meet the recommended dietary allowances i.e. with the shortage of 10-15%, this is an indication that the street children should be aware of their daily food consumption. The most common diseases suffered by the respondents were acute respiratory infections (ARI) (47%). In addition, 22.7 % and 18.4 % of them suffered from diarrhoea and skin diseases, respectively. Blood haemoglobin status of street children shows that the incidence of anemia was 29.3%. Based on the classification of nutritional status, 42.7% and 80.4 % of street children were underweight and stunted, respectively.
NILAI INDEKS GLIKEMIK BEBERAPA JENIS PENGOLAHAN JAGUNG MANIS (Zea mays saccharata Sturt) Sri Nur Amalia; Rimbawan Rimbawan; Mira Dewi
Jurnal Gizi dan Pangan Vol. 6 No. 1 (2011)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.077 KB) | DOI: 10.25182/jgp.2011.6.1.36-41

Abstract

The implementation of glycemic index can be used as basis for selecting carbohydrate food source to enhance and or to maintain health.The objective the following study was to analyze the glycemic indices of sweet corn with three different cooking methods.  Glycemic index values of boiled, sauted and grilled sweet corn were 41.22, 31.08 and 55.31 respectively. Based on those results, grilled sweet corn was classified as food with medium glycemic index, whereas both of boiled and sauted sweet corn were classified as food with low glycemic index.
HUBUNGAN STATUS GIZI DAN TEKANAN DARAH DENGAN KADAR C-REACTIVE PROTEIN DARAH PADA SUBJEK DISLIPIDEMIA Mira Dewi; Rimbawan Rimbawan; Agustino Agustino
Jurnal Gizi dan Pangan Vol. 8 No. 1 (2013)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.012 KB) | DOI: 10.25182/jgp.2013.8.1.17-24

Abstract

The objective of this study was to analyze the association of nutritional status (Body Mass Index, waist circumference, waist-hip ratio, and body fat mass) and blood pressure with inflammation status which was assessed by blood C-reactive protein level in dyslipidemic subjects. The study design was cross sectional survey involving 81 dyslipidemic subjects in Bogor. The study showed that there were significant correlations between BMI, waist-hip ratio, body fat mass, and diastolic blood pressure with blood CRP level (p<0.05). In conclusion, the higher percentage of over nutritional status, body fat mass, and diastolic blood pressure, the higher status of inflammation.Keywords:
ASUPAN KALSIUM, STATUS GIZI, TEKANAN DARAH DAN HUBUNGANNYA DENGAN KELUHAN SENDI LANSIA DI PANTI WERDHA BANDUNG Nining Tyas Triatmaja; Ali Khomsan; Mira Dewi
Jurnal Gizi dan Pangan Vol. 8 No. 1 (2013)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.736 KB) | DOI: 10.25182/jgp.2013.8.1.25-32

Abstract

The objective of this study was to determine the relationship of calcium intake, nutritional status, and blood pressure to joint pain among elderly in nursing homes in Bandung. The study design was cross-sectional study. Subjects were consisted of 12 elderly men and 69 elderly women from four nursing homes in Bandung. Most subjects had joint pain (59.3%), hypertension (30.9%), and were overweight (39.5%). There was no significant relationship between frequency of consumption of calcium food sources and nutritional status, blood pressure, joint pain, and the level of joint pain (p>0.05). There was no significant relationship between joint pain and the level of joint pain with blood pressure and nutritional status.
HUBUNGAN ASUPAN SERAT DENGAN STATUS GIZI DAN PROFIL LIPID DARAH PADA ORANG DEWASA DISLIPIDEMIA Lilik Kustiyah; Maya Utami Widhianti; Mira Dewi
Jurnal Gizi dan Pangan Vol. 8 No. 3 (2013)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.516 KB) | DOI: 10.25182/jgp.2013.8.3.195-200

Abstract

The objective of this study was to analyze the association of fiber consumption with nutritional status and blood lipid profile in dyslipidemic adults. The design study was cross sectional survey involving 79 subjects. The results showed that there were significant correlations between energy intake with High Density Lipoprotein (HDL) cholesterol and total cholesterol, fat intake with BMI (Body Mass Index), and BMI with Low Density Lipoprotein (LDL) cholesterol and total cholesterol (p<0.05). There was no significant correlation between consumption of fiber with nutritional status and blood lipid profile (p>0.05). In conclusion, most of the dyslipidemia subjects were obese. Dyslipidemia subjects should keep their intake of energy and fat in recommended ranges in order not to be obese and keep the BMI in normal range to avoid abnormalities of blood lipid profile.
PENGARUH INTERVENSI PENAMBAHAN FITOSTEROL PADA MINYAK GORENG SAWIT TERHADAP PROFIL LIPID SUBJEK DENGAN SINDROMA METABOLIK Naufal Muharam Nurdin; Rimbawan Rimbawan; Drajat Martianto; Mira Dewi
Jurnal Gizi dan Pangan Vol. 9 No. 2 (2014)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.618 KB) | DOI: 10.25182/jgp.2014.9.2.%p

Abstract

The objective of this study was to evaluate the effect of addition of phytosterol on palm oil among metabolic syndrome (MetS) subject. This study was a clinical trial with randomized double blind controlled design. Thirty adult subject (age 40—60) with MetS are divided into 2 groups. Intervention group were given palm oil enriched with 6.5% phytosterol and used as cooking oil for habitual use for 8 week. The control group were given palm oil without phytosterol. Nutrition intake was assesed by recalls every 2 weeks. Blood lipid profile, blood glucose and anthropometry were analyzed at pre and post intevention. After 8 week intervention, estimated total palm cooking oil and phytosterol consumption on intervention group were 46±23 g/day and 2±1 g/day. There were no significant change of the LDL-choleseterol level (p>0.05) but there were a significant reductiton of serum total cholesterol and triglyceride level compared the control group (respectively p=0.007 and p=0.027). In conclusion with high level palm cooking oil intake, estimated phytosterol intake had reached the target and there are slight improvement of the lipid profile on MetS subject.