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All Journal Jurnal Gizi dan Pangan Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan VALENSI Jurnal Keteknikan Pertanian Pharmaciana: Jurnal Kefarmasian Agrointek Perspektif : Review Penelitian Tanaman Industri Jurnal Teknologi Pertanian Majalah Obat Tradisional Warta IHP (Warta Industri Hasil Pertanian) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology ANNALES BOGORIENSES Indonesian Food Science and TechnologyJournal Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Jurnal Ilmu Kefarmasian Indonesia Jurnal Mutu Pangan : Indonesian Journal of Food Quality Perspektif, Review Penelitian Tanaman Industri AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment) Policy Brief Pertanian, Kelautan, dan Biosains Tropika Halal Studies and Society Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research)
Puspo Edi Giriwono
Departemen Ilmu Dan Teknologi Pangan, Fakultas Teknologi Pertanian, Institut Pertanian Bogor Jl. Lingkar Akademik, Kampus IPB Darmaga, Bogor 16680, Indonesia
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Torbangun (Plectranthus amboinicus (Lour.) Spreng) Leaf Extract Upregulates Expression of Lactation-Related Genes in Human Mammary Epithelial Cells MCF-12A Tafzi, Fitry; Andarwulan, Nuri; Giriwono, Puspo Edi; Dewi, Fitriya N.
Indonesian Food Science and Technology Journal Vol. 8 No. 1 (2024): Volume 8. Number 1, December 2024 |IFSTJ|
Publisher : Department of Technology of Agricultural product (THP) Jambi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/ifstj.v8i1.37364

Abstract

Torbangun (Plectranthus amboinicus (Lour). Spreng) leaf is a herbaceous plant capable of increasing breast milk, although the mechanism of bioactive compounds on the molecular level remains relatively unknown. Therefore, this study aimed to evaluate the effect of torbangun leaf extract on the expression of genes associated with alveologenesis and the formation of milk protein, namely prolactin receptor (PRLR), glucocorticoid receptor (GR), signal transducer, as well as activator of transcription 5A (STAT5A) and b-casein (CSN2). The result showed that the extract and fractions of torbangunleaf had IC50 values above 20 ug/ml against MCF-12A cells. Ethyl acetate fraction also enhanced the expression of gene GR, STAT5A, and CSN2. Water fraction of torbangun leaf enhanced expression of gene PRLR, GR, STAT5A, and CSN2. The bioactive compound was found to increase the expression of genes associated with proliferation, alveologenesis, and the formation of milk protein during gestation and lactation.
CONSUMPTION OF CARBONATED BEVERAGES AND THE RISK FOR GASTROINTESTINAL DISEASE: A SYSTEMATIC REVIEW Puspo Edi Giriwono; Nuri Andarwulan; Rimbawan Rimbawan; Deddy Muchtadi
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 37 No. 1 (2014)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v37i1.4010.69-76

Abstract

ABSTRACTIssues of different effects of carbonated soft drinks to human health have been circulated and analyzed in both scientific and non-scientific approaches. However, there is few publications discussing the specific effect of carbonation on human health and, more often than not, studies have largely concentrated on the effect of sugar or calorie content in carbonated beverages in affecting our health. Thus the effect of carbonation itself on human health is then lost in arguments contradicting or reaffirming the effect of carbonated soft drinks. We conducted this systematic review to specifically observe current findings on the effect of carbonation in beverages on human health. This systematic review was conducted using Scirus search engine to list articles relevant with keywords such as CO2, carbonated beverage, carbonation, sparkling water, gastrointestinal, gastro-esophageal and adenocarcinoma. Next, articles were obtained from numerous databases and screened for their relevance and context. Finally, peer reading and discussion were conducted for the writing of this article. The results of this systematic review observed three major article subjects currently correlated with exclusive effect of carbonation on gastrointestinal health. Published studies indicate that oral cavity/dental health, gastro-esophageal reflux and most recently esophageal adenocarcinoma are discussed frequently and observed in population studies in different countries consuming significant quantities of carbonated beverages. Eight articles (40%) discussed dominant factors not correlated with carbonation which significantly affect dental erosions. Six (33%) articles observed no clear clinical significance carbonation promotes or exacerbate gastro-esophageal reflux. Interestingly, five (27%) articles reported insignificant correlation, even inversed, of carbonation on esophageal carcinoma.Currently available scientific studies on populations in multiple countries show that the effect of carbonation in beverages has non-significant (statistically) effect on the health of the gastrointestinal tract.Keywords: Carbonated beverages, gastrointestinal, GERD, esophageal adenocarcinoma*ABSTRAKIsu mengenai dampak karbonasi pada minuman ringan terhadap kesehatan, terutama kesehatan saluran pencernaan, telah banyak beredar beserta pembahasannya, baik secara ilmiah maupun tidak. Efek kesehatan dari unsur karbonasi pada minuman ringan sangat jarang dibahas dan dipublikasikan pada jurnal ilmiah. Melakukan systematic review status ilmiah terkini khusus mengenai dampak karbonasi dalam berbagai produk minuman terhadap kesehatan saluran pencernaan. Scirus search engine digunakan untuk melacak artikel ilmiah dengan kata kunci khusus, yakni CO2, carbonated beverage, carbonation, sparkling water, gastrointestinal, gastro-esophageal and adenocarcinoma. Tahap ini dilanjutkan dengan penapisan (screening) untuk kesesuaian subjek artikel dan akses. Tahap terakhir adalah focus group discussion bersama peer/ahli dalam bidang gizi, kesehatan dan keamanan pangan. Hasil dari systematic review memperlihatkan bahwa terdapat tiga kelompok pembahasan utama yang berhubungan dengan efek karbonasi terhadap kesehatan saluran pencernaan, yaitu kesehatan pada gigi/rongga mulut, refluks esofagus dan kanker esofagus. Hasil skrining menunjukkan 40 persen published articles membahas dental health, 33 persen membahas gastro-oestrophageal health dan 27 persen membahas esophageal adenocarcinoma. Delapan artikel yang membahas dental health menunjukkan erosi yang dapat terjadi disebabkan oleh faktor lain di luar karbonasi. Enam artikel yang membahas gastro-oestrophageal health menunjukkan tidak ada korelasi antara faktor karbonasi dengan refluks ataupun refluks kronis yang terjadi. Sementara 5 artikel memperlihatkan observasi yang berkorelasi terbalik dengan risiko munculnya kanker esofagus. Systematic review menunjukkan bahwa saat ini berbagai artikel ilmiah relevan yang sudah dipublikasikan menyimpulkan dampak karbonasi pada minuman terhadap kesehatan saluran pencernaan tidak signifikan secara statistik klinis. [Penel Gizi Makan 2014, 37(1): 69-76]Kata kunci: Minuman berkarbonasi, penyakit saluran pencernaan, GERD, esophageal adenocarcinoma
RISIKO PAPARAN KADMIUM DARI COKELAT BATANG PADA KONSUMEN DI INDONESIA Dias Erfan; Lilis Nuraida; Puspo Edi Giriwono
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 44 No. 2 (2021): PGM VOL 44 NO 2 TAHUN 2021
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v44i2.5056

Abstract

ABSTRACT Cadmium (Cd) is a common contaminant found in cocoa derivative products such as chocolate bars because it is carried away from cocoa beans. The popularity of chocolate bars among Indonesian consumers may pose a health risk due to Cd content in chocolate bars. The present study aimed to estimate the risk of dietary exposure on Cd from chocolate bars to the Indonesian population. The data of chocolate bars consumption in 1324 respondents were obtained from Individual Food Consumption Survey in 2014. Samples of 10 different variants of chocolate bars were collected from markets in Indonesia from the provinces of DKI Jakarta and West Java. All samples were analyzed for their Cd content using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). The results show the highest average consumption of chocolate bars was found in adolescence (13-18 years), followed by a toddler (6-59 months) and children (5-12 years). Cd content in chocolate bars ranged between 0.00012 mg/kg to 0.12 mg/kg with the highest content was found in one variant of sweet dark chocolate bar. None of the samples contained Cd above the maximum limits of Cd (0.5 mg/kg in chocolate bar products) as regulated by NADFC. The highest average exposure to Cd from chocolate bars was found in toddlers (6-59 months), 0.09336 µg/kg BW/day. The average, maximum, and P95th exposures to Cd from chocolate bars in all age groups did not exceed its Provisional Tolerable Monthly Intake (PTMI), indicating that the exposure to Cd through chocolate bar products do not pose any potential risk to human health. ABSTRAK Kadmium (Cd) merupakan kontaminan yang umum ditemukan pada produk turunan kakao seperti coklat batang karena terbawa dari biji kakao. Popularitas cokelat batang di kalangan konsumen Indonesia dapat menimbulkan risiko kesehatan akibat kandungan Cd dalam cokelat batang. Penelitian ini bertujuan untuk memperkirakan risiko tingkat paparan Cd dari cokelat batang pada populasi di Indonesia. Data konsumsi cokelat batang pada 1324 responden diperoleh dari Survei Konsumsi Makanan Individu tahun 2014. Sebanyak 10 sampel batang cokelat dari varian yang berbeda dikumpulkan dari pasar di Indonesia dari provinsi DKI Jakarta dan Jawa Barat. Seluruh sampel dianalisis kandungan Cd-nya menggunakan metode Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). Hasil penelitian menunjukkan bahwa rata-rata konsumsi cokelat batang tertinggi ditemukan pada kelompok remaja (13-18 tahun), diikuti oleh balita (6-59 bulan) dan anak-anak (5-12 tahun). Kadar Cd pada seluruh cokelat batang berkisar antara 0,00012 mg/kg sampai 0,12 mg/kg dengan kadar Cd tertinggi terdapat pada salah satu varian coklat batang hitam manis. Tidak ada sampel yang mengandung Cd di atas batas maksimum Cd (0,5 mg/kg pada produk cokelat batang) sebagaimana diatur oleh BPOM. Rata-rata paparan Cd dari cokelat batang tertinggi ditemukan pada kelompok balita (6-59 bulan) yaitu sebesar 0,09336 µg/kg bb/hari. Nilai paparan rata-rata, maksimum dan P95 untuk Cd dari cokelat batang di kelompok seluruh umur tidak melebihi Provisional Tolerably Monthly Intake (PTMI) yang menunjukkan bahwa paparan Cd melalui produk cokelat batang tidak menimbulkan risiko potensial bagi kesehatan manusia. [Penel Gizi Makan 2021, 44(2):59-70]
Variasi lama waktu fermentasi terhadap karakteristik kimia teh kombucha: meta-analisis Rina Dias Agustin; Puspo Edi Giriwono; Endang Prangdimurti
AGROINTEK Vol 18, No 3 (2024)
Publisher : Agroindustrial Technology, University of Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/agrointek.v18i3.19200

Abstract

One type of beverage that has functional effects and has been known for a long time is kombucha tea, a fermented drink made with tea leaves, sugar, and Symbiotic Culture of Bacteria and Yeast (SCOBY). Kombucha tea tastes sourly like apple vinegar, sparkling contains polyphenol compounds, organic acids, other biomolecules, and probiotics. The fermentation time is a factor that needs to be considered in making kombucha tea. Much research has been done on kombucha tea, but the variation in duration of the fermentation process is very diserve, so a meta-analysis is needed to obtain valid and informative conclusions from a comprehensive study about the effect of fermentation time on the kombucha tea chemical characteristics. The PRISMA flowchart and the effect size of Standardized Mean Difference (SMD) in the form of Hedges'd were choosen as  a quantitative synthesis method of meta-analysis. The results showed that the fermentation process conducted for 8-14 days had a strong effect on all parameters (flavonoid, ethanol, acetic acid levels, total phenolic, total acidity, and antioxidant activity) with SMD values 0.8, p values 0.001 to 0.732, and heterogeneity values of 57,62% to 89,40%. Kombucha tea, with a fermentation time of 7 days had significantly higher antioxidant activity. The length of the fermentation process has the strongest effect on the acetic acid levels of kombucha tea.
Development of halal assurance system for shoyu production Tanaka, Darren; Kusnandar, Feri; Giriwono, Puspo Edi
Halal Studies and Society Vol. 1 No. 2 (2024): May 2024
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/hass.1.2.43-49

Abstract

Muslim population in Indonesia was predicted to reach 214 million by 2019, making it a lucrative market from a business perspective. Muslims have the right to obtain and consume halal food products. Food and beverages must be manufactured from raw halal materials and processed in a manner that retains halal status. For instance, shoyu, a Japanese soy sauce widely consumed by Indonesians, traditionally contains a mixture of wheat and soybean fermented in two stages. Non-halal soy sauce may contain brewery or khamr alcohol and pork-derived substances as flavoring ingredients. Therefore, halal assurance system (HAS) 23000 was developed by LPPOM MUI (Food, Drug and Cosmetic Research Institute of Indonesian Ulema Council) and aimed at ensuring a product is free from contamination by haram or najis. HAS development for halal shoyu product line at Kamada Soy Sauce Inc. included conducting a preliminary audit using the gap analysis method. The development was considered complete once all 11 principles of HAS 23000 had been fulfilled. A post-audit was then performed using the same gap analysis method to compare the conditions before and after development. Subsequently, a risk analysis using failure mode and effect analysis (FMEA) was performed based on audit results and brainstorming sessions with the company. Construction of a fishbone diagram was carried out using the calculated risk probability number during FMEA risk analysis.
Utilization of Suji Leaves Extract (Pleomele Angustifolia N.E Brown) in Inhibiting Carrageenan-Induced Inflammation on Rats Koja, Reni; Prangdimurti, Endang; Giriwono, Puspo Edi
AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment) Vol. 8 No. 1 (2024)
Publisher : Asia Pacific Network for Sustainable Agriculture, Food and Energy (SAFE-Network)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29165/ajarcde.v8i1.371

Abstract

Suji leaf (Pleomele angustifolia N.E. Brown) has long been used as an ingredient for traditional medicines. This study seeks to evaluate the anti-inflammatory activity of suji leaf extract in terms of its ability to reduce oedema in the hind paws of rats. Six groups were treated: negative control, positive control given diclofenac sodium as anti-inflammatory medication, two groups of suji leaf extract powder (SEP) with doses of 300 and 800 mg/kg, acetone extract of suji leaf (AES), and a group of acetone extract of SEP (EA-SEP) at a dose of 500 mg/kg with oral administration. Injections of 1% carrageenan suspension into the right hind paw of rats induced inflammation. The results demonstrated that SEP administered at a dose of 800 mg/kg has an inflammatory capacity (80.56%), AES (56.94%), and AE-SEP (75.7%). Chlorophyll, total phenol, and antioxidant capacity in SEP (9.0809 mg /g sample; 3.7354 mg GAE/g sample; 3.04 mg AAE/g sample), AES (4.6471 mg /g sample; 0.9994 mg GAE/g sample; 3.26 mg AAE/g sample), and AE-SEP (6.4912 mg /g sample; 2.1703 mg GAE/g sample; 2.55 mg AAE/g sample). According to qualitative test results, Suji extract contains bioactive compounds of the flavonoid group, saponins, steroids, and triterpenoids. It is believed that phenolic compounds function as anti-inflammatory agents.
Effect of Locally Produced Ready-to-Use Therapeutic Food on Children under Five Years with Severe Acute Malnutrition: A Systematic Review Rimbawan, Rimbawan; Nasution, Zuraidah; Giriwono, Puspo Edi; Tamimi, Kharisma; Fadly, Khaerul; Noviana, Astrid
Jurnal Gizi dan Pangan Vol. 17 No. 2 (2022)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.62 KB) | DOI: 10.25182/jgp.2022.17.2.123-138

Abstract

This review assessed the effect of Ready-to-Use Therapeutic Food (RUTF) on children under five years with Severe Acute Malnutrition (SAM). The reviewed studies were obtained from six databases. Using the search strategy, 3,521 studies were selected. After title and abstract screening, 75 studies were obtained for further full article screening. The inclusion criteria were types of study (RCT, quasi-RCT, or crossover), participants (SAM children aged 6−60 months with no complications), interventions (locally produced RUTF and standard RUTF), and outcome measures (recovery rate, mortality rate, weight gain rate, height gain rate, length of stay, weight-for-age z score, height-for-age z score, weight-for-length z score, anemia status, blood iron status, serum albumin, plasma amino acid level, adverse effects and acceptability of RUTF). A total of 33 studies were included in this review. Nine out of twenty-two studies that used standard RUTF had positive effects on recovery outcomes in children with SAM. The alternative RUTF produced from local protein sources showed slightly lower positive effects on SAM treatment than those of standard RUTF. Since the studies used different methods to assess the outcome, no formula could be selected as the best formula and selection should be made based on individual research objectives. In conclusion, both standard and the alternative locally produced RUTF can be applied for treatment of SAM by considering the local preferences, ingredients availability, production sustainability and product safety.
Product Formulation of Ready to Use Fish Food (RUFF) from Snakehead Fish Flour (Channa striata) Giriwono, Puspo Edi; Haryanto, Safira P.A; Saraswati, Saraswati
Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Vol. 14 No. 6 (2025): December 2025
Publisher : The University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtepl.v14i6.2017-2025

Abstract

RUFF (ready-to-use fish food) is a nutrient and calorie-dense food with high protein and energy consumed by children under five years of age who suffer from severe acute malnutrition. RUFF in this study was designed to be the alternative product for RUTF (ready-to-use therapeutic food) using snakehead fish flour as skim milk substitute. This study aims to determine the suitability of snakehead fish flour as an animal protein alternative, obtain the RUFF formula that meets FAO and WHO standards, and determine the consumer acceptance. The research investigated different amount of snakehead fish flour in the RUFF formulation. There were 3 formulas with different snakehead fish flour, i.e. 20% (F1), 22% (F2), and 24% (F3). The results of the analysis showed that the highest protein content was found in formula F3 (14.35 ±0.72)% with moisture content of 2.32 ± 0.06%, ash content of 2.56 ± 0.04%, fat content of 29.39 ± 0.24%, and carbohydrate content of 51.37 ± 0.94%. All three RUFF formulations meet the nutritional standards set by the FAO and WHO. The hedonic rating test results and ranking showed that the most preferred formula by the panelist was formula F1 containing 20% snakehead fish flour with an average rate of 7.46 (like). Formula F1 is the formula of RUFF with the highest rate of consumer acceptance.
Probabilistic Estimation of Bromate Exposure from the Consumption of Bottled Drinking Water Distributed in the Bogor Region Handayani, Yani; Giriwono, Puspo Edi; Herawati, Dian
Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Vol. 14 No. 6 (2025): December 2025
Publisher : The University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jtepl.v14i6.2057-2068

Abstract

Bottled drinking water is a source of human exposure to bromate, a disinfection by-product (DBP) with adverse health effects and carcinogenic potential. Little is known about bromate exposure levels and risk characterization, particularly in Bogor, Indonesia. The study aimed to obtain data on bromate concentrations in bottled drinking water, estimate bromate exposure levels based on individual consumption, and assess the risk characterization. Bromate exposure were calculated based on bromate concentrations and individual consumption, across five age groups. Bromate exposure and risk characterization were estimated probabilistically using Monte Carlo simulation. In this study, 37 bottled drinking water samples were collected from large and small manufacturers and retailers in Bogor and analyzed for bromate content. Bromate was detected in 30 samples, with 5 samples exceeding the Indonesian national standard of 10 µg/L. The average concentration was 6.88±8.88 μg/L. Exposure estimates indicate that, for all age groups, the average and 95th percentile values are 0.1086±0.0484 µg/kg BW/day and 0.4044 µg/kg BW/day in Bogor and 0.1492±0.2820 µg/kg BW/day and 0.5495 µg/kg BW/day in Indonesia, respectively. Values below the tolerable daily intake (TDI) limit for non-cancer risk, so the risk characterization for all age groups can be considered as safe.
Co-Authors Afif Arwani Aliwikarta, Kuswanto Andi Nadya Tita Alia Andini Giwang Kinasih Antung Sima Firlieyanti Apon Zaenal Mustopa Apon Zaenal Mustopa Ayu Puspitalena RTR Betty Sri Laksmi Jenie Cesar Welya Refdi Christian Liguori, Christian Dahrul Syah DAHRUL SYAH Dahrul Syah Deddy Muchtadi Dedi Fardiaz Dewi, Fitriya N. Dian Herawati Dias Erfan Dias Indrasti Eko Hari Purnomo Elsera Br Tarigan Elsera Br Tarigan, Elsera Br Endang Prangdimurti Enny Rimita Sembiring Fadly, Khaerul Farida, Eko Feri Kusnandar FITRY TAFZI Fransiska R. Zakaria Fransiska Rungkat FRANSISKA RUNGKAT ZAKARIA FRANSISKA RUNGKAT ZAKARIA Handayani, Yani Hanifah Nuryani Lioe Harsi D. Kusumaningrum Hartati Chairunnisa Haryanto, Safira P.A Iftita Rakhma Ikrima Indrayana, Stefanus Kartika Sari Kharisma Tamimi Kusmajadi Suradi Kusmajadi Suradi Kuswanto Aliwikarta Lidwina Lidwina Lilis Nuraida Maggy Thenawidjaja Suhartono Masayu Nur Ulfa Nasution, Zuraidah Noviana, Astrid Nugraha Edhi Suyatma Nur Wulandari Nuri Andarwulan Palupi, Nurheni Sri Pamungkas, Joko Purwiyatno Hariyadi Ratna Sari Listyaningrum Reni Koja Rimbawan , Rimbawan Rimbawan Rina Dias Agustin RTR, Ayu Puspitalena SARASWATI SARASWATI Sari Apriliana Satya Nugroho Sentani Chasfila Sri Yadial Chalid Stefanus Indrayana Suyanto Suyanto Tanaka, Darren Wahid Yulianto Wendry Setiyadi Putranto Wihardi, Alfin Maulana Winiati Pudji Rahayu Wiwi Hartuti Zakaria Zakaria