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All Journal Jurnal Gizi dan Pangan Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan VALENSI Jurnal Keteknikan Pertanian Pharmaciana: Jurnal Kefarmasian Agrointek Perspektif : Review Penelitian Tanaman Industri Jurnal Teknologi Pertanian Majalah Obat Tradisional Warta IHP (Warta Industri Hasil Pertanian) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology ANNALES BOGORIENSES Indonesian Food Science and TechnologyJournal Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Jurnal Ilmu Kefarmasian Indonesia Jurnal Mutu Pangan : Indonesian Journal of Food Quality Perspektif, Review Penelitian Tanaman Industri AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment) Policy Brief Pertanian, Kelautan, dan Biosains Tropika Halal Studies and Society Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research)

Puspo Edi Giriwono

Departemen Ilmu Dan Teknologi Pangan, Fakultas Teknologi Pertanian, Institut Pertanian Bogor Jl. Lingkar Akademik, Kampus IPB Darmaga, Bogor 16680, Indonesia

Author-ID : 2465078

Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences

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ANALISIS KOMPARATIF MINERAL MIKRO DAN ANTI NUTRISI PADA BERAS ANTARA PADI REKAYASA GENETIK DAN TETUANYA Enny Rimita Sembiring; Puspo Edi Giriwono; Satya Nugroho; Maggy Thenawidjaja Suhartono
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 8 No. 2 (2021): December 2021
Publisher : Balai Bioteknologi, Badan Pengkajian dan Penerapan Teknologi (BPPT)

Comparative analysis is important aspect in food safety of transgenic crops to determine the effect of transgene on nutritional and anti-nutritional contents. This research was aimed to determine the concentration of Fe, Zn, phytic acid, and anti-trypsin activity, then assess the equivalence between transgenic rice and non-transgenic rice. Fe and Zn concentration was carried out using energy-dispersive x-ray fluorescence spectrometry. Anti-nutritional phytic acid and anti-trypsin activity were performed using visible light spectrophotometry. The data obtained were statistically tested using Independent sample t-test. These results indicated that the concentration of Fe, Zn, phytic acid, and anti-trypsin activity in 6 transgenic rice events were equivalent to non-transgenic rice. In conclusion, the transgene did not affect Fe, Zn, phytic acid, and anti-trypsin activities in brown rice of 6 transgenic rice events carrying cry1B::cry1Aa fusion genes. Analisis komparatif adalah salah satu aspek penting dalam keamanan pangan tanaman produk rekayasa genetik (PRG) untuk mengetahui pengaruh transgen terhadap kandungan nutrisi dan anti nutrisi. Pada penelitian ini dilakukan analisis komparatif konsentrasi mineral mikro Fe, Zn, asam fitat, dan aktivitas anti tripsin pada beras pecah kulit dari 6 galur padi PRG pembawa fusi gen cry1B::cry1Aa terhadap padi non-PRG Rojolele tetuanya. Analisis konsentrasi mineral mikro Fe dan Zn menggunakan metode energy-dispersive x-ray fluorescence spectrometry (ED-XRF) dengan 3 ulangan. Analisis konsentrasi anti nutrisi asam fitat dan aktivitas anti tripsin dilakukan menggunakan metode spektrofotometri sinar tampak dengan 8 ulangan. Data yang diperoleh diuji secara statistik menggunakan Independent sample t-test. Hasil yang diperoleh menunjukkan konsentrasi mineral mikro Fe, Zn, asam fitat, dan aktivitas anti tripsin pada beras dari 6 galur padi PRG pembawa fusi gen cry1B::cry1Aa setara dengan padi non-PRG Rojolele tetuanya. Kesimpulannya bahwa transgen tidak mempengaruhi kandungan mineral mikro Fe, Zn, asam fitat, dan aktivitas anti tripsin pada beras dari 6 galur padi PRG pembawa fusi gen cry1B::cry1Aa.

Peranan Teknologi Proses Pengolahan Pangan dalam Penurunan Alergenisitas Kerang-kerangan: Meta-analisis Andi Nadya Tita Alia; Nurheni Sri Palupi; Puspo Edi Giriwono
Jurnal Ilmu Pertanian Indonesia Vol. 28 No. 3 (2023): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18343/jipi.28.3.491

Shellfish is widely consumed globally, one of the main reasons is because it contains good nutrition for health. The increased consumption also leads to adverse health problems such as food allergy. Food allergy is hypersensitivity reaction of the immune system caused by consumption or exposure to food. Various food processing methods has been proven to alter shellfish allergenicity with different effectiveness. This study aims to determine the most effective processing method to reduce shellfish allergenicity through meta-analysis. In total of 19 articles were obtained using PRISMA diagram, with publication year range 2006-2020. Data were analyzed to determine Standardized Mean Difference (SMD) with 95% confidence interval. Moist heating, high hydrostatic pressure, irradiation, and ultrasound processing have significant effect (p < 0,05) in reducing shellfish allergenicity. Meanwhile, boiling and roasting processing did not have a significant effect. Based on the results of the meta-analysis, high hydrostatic pressure is the most effective method in reducing shellfish allergenicity because it has the highest effect size value with -7,25 (95% CI: -9,11 s.d. -5,4; p < 0,00001). Keywords: allergenicity, food processing, meta-analysis, shellfish

Sintesis Minyak Makan Kaya Diasilgliserol dari RBDP Olein dengan Metode Gliserolisis Enzimatis serta Pemurniannya Sari Apriliana; Nur Wulandari; Puspo Edi Giriwono
Warta Industri Hasil Pertanian Vol 40, No 1 (2023)
Publisher : Balai Besar Standardisasi dan Pelayanan Jasa Industri Agro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32765/wartaihp.v40i1.7728

ABSTRAK: Terjadinya masalah gizi terkait konsumsi minyak dan lemak, telah mendorong masyarakat untuk menggunakan minyak yang memiliki dampak positif bagi kesehatan (minyak sehat), seperti minyak makan yang kaya kandungan diasilgliserol (DAG). Penelitian ini bertujuan untuk mensintesis minyak makan kaya DAG dari refined bleached deodorized palm (RBDP) olein melalui metode gliserolisis enzimatis, serta meningkatkan kadar DAG pada minyak makan tersebut melalui proses pemurnian. Sintesis minyak makan kaya DAG secara gliserolisis enzimatis dilakukan dengan mereaksikan RBDP olein dan gliserol 2:1 (mol/mol) menggunakan katalis enzim lipase TL IM 10% (b/b) pada suhu 60 oC selama 26 jam. Proses tersebut mampu meningkatkan kadar DAG minyak makan secara signfikan, yaitu semula 9,41%+0,03 menjadi 47,85%+0,09. Tahap pemurnian selanjutnya dengan metode P2 (saponifikasi menggunakan NaOH 10%) dapat meningkatkan kandungan DAG minyak makan dari 47,85%+0,09 menjadi 54,68%+0,27. Sintesis dan proses pemurnian yang diterapkan dalam penelitian ini telah mampu meningkatkan kadar DAG pada minyak makan 5,8 kali lipat lebih tinggi dibandingkan bahan baku RBDP olein. Sifat fisikokimia minyak makan kaya DAG hasil pemurnian mengalami perubahan dibandingkan RBDP olein, terutama dari bentuk fisiknya yang menjadi semipadat, serta bilangan Iod-nya yang lebih rendah.

Estimasi Risiko Migrasi Bisfenol A (BPA) Dari Kemasan Logam Pangan Olahan Di Indonesia Nugraha Edhi Suyatma; Sentani Chasfila; Puspo Edi Giriwono
Jurnal Keteknikan Pertanian Vol. 11 No. 2 (2023): Jurnal Keteknikan Pertanian
Publisher : PERTETA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19028/jtep.011.2.253-267

Logam merupakan salah satu jenis kemasan pangan yang banyak digunakan, untuk mencegah korosi. Logam biasanya dilapisi dengan pelapis epoksi resin seperti bisfenol A (BPA). BPA dapat mempengaruhi sistem endokrin dan dapat menyebabkan kerusakan pada berbagai jaringan serta organ. Penelitian ini bertujuan untuk mengetahui kandungan migrasi BPA pada kemasan kaleng sarden dan kornet serta paparannya pada penduduk Indonesia. Sampel yang digunakan adalah kemasan kaleng kosong untuk sarden dan kornet masing-masing 12 buah kemudian dianalisis menggunakan HPLC-UV Vis. Hasilnya menunjukkan bahwa konsetrasi migrasi BPA dalam kemasan kaleng sarden (menggunakan simulan etanol 20%) berkisar antara 0,005 – 0,05 mg/kg. Sedangkan dalam kemasan kaleng kornet (menggunakan simulan etanol 10%) sebesar 0,005 mg/kg. Rerata estimasi paparan perhari migrasi BPA dari konsumsi sarden dalam kaleng tertinggi terdapat pada usia 24-59 bulan yaitu 0,0546 µg/kgBB, sedangkan estimasi paparan perhari migrasi BPA dari konsumsi kornet dalam kaleng tertinggi terdapat pada usia anak 5-12 tahun yaitu sebesar 0,0066 µg/kgBB. Nilai risiko P95 untuk paparan migrasi BPA dari konsumsi sarden dalam kaleng pada seluruh kelompok usia sebesar 2,3883% sedangkan nilai risiko paparan dari konsumsi kornet dalam kaleng pada seluruh kelompok usia sebesar 0,3846%. Nilai risiko tersebut tidak melebihi asupan harian yang dapat ditoleransi sementara (tTDI), yang mengindikasikan bahwa paparan migrasi BPA melalui kemasan kaleng sarden dan kornet akibat mengkonsumsi sarden dan kornet tidak menimbulkan risiko bahaya terhadap kesehatan manusia di Indonesia.

Utilization of Suji Leaves Extract (Pleomele Angustifolia N.E Brown) in Inhibiting Carrageenan-Induced Inflammation on Rats Reni Koja; Endang Prangdimurti; Puspo Edi Giriwono
AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment) Vol. 8 No. 1 (2024)
Publisher : Asia Pacific Network for Sustainable Agriculture, Food and Energy (SAFE-Network)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29165/ajarcde.v8i1.371

Suji leaf (Pleomele angustifolia N.E. Brown) has long been used as an ingredient for traditional medicines. This study seeks to evaluate the anti-inflammatory activity of suji leaf extract in terms of its ability to reduce oedema in the hind paws of rats. Six groups were treated: negative control, positive control given diclofenac sodium as anti-inflammatory medication, two groups of suji leaf extract powder (SEP) with doses of 300 and 800 mg/kg, acetone extract of suji leaf (AES), and a group of acetone extract of SEP (EA-SEP) at a dose of 500 mg/kg with oral administration. Injections of 1% carrageenan suspension into the right hind paw of rats induced inflammation. The results demonstrated that SEP administered at a dose of 800 mg/kg has an inflammatory capacity (80.56%), AES (56.94%), and AE-SEP (75.7%). Chlorophyll, total phenol, and antioxidant capacity in SEP (9.0809 mg /g sample; 3.7354 mg GAE/g sample; 3.04 mg AAE/g sample), AES (4.6471 mg /g sample; 0.9994 mg GAE/g sample; 3.26 mg AAE/g sample), and AE-SEP (6.4912 mg /g sample; 2.1703 mg GAE/g sample; 2.55 mg AAE/g sample). According to qualitative test results, Suji extract contains bioactive compounds of the flavonoid group, saponins, steroids, and triterpenoids. It is believed that phenolic compounds function as anti-inflammatory agents.

Risiko Paparan Formaldehida dari Beberapa Jenis Ikan pada Masyarakat di Kecamatan Dramaga, Bogor, Jawa Barat Wihardi, Alfin Maulana; Giriwono, Puspo Edi; Indrasti, Dias
Jurnal Mutu Pangan : Indonesian Journal of Food Quality Vol. 10 No. 2 (2023): Jurnal Mutu Pangan
Publisher : Department of Food Science and Technology (ITP), Faculty of Agricultural Technology, Bogor Agricultural University (IPB) in collaboration with the Indonesian Food and Beverage Association (GAPMMI), the National Agency of Drug and Food Control, and th

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jmpi.2023.10.2.108

Residual formaldehyde compounds may be found in fish either naturally or intentionally added. Exposure of formaldehyde from food can cause damage to the gastrointestinal tract, liver, kidney, and is carcinogenic in humans. This study aims to estimate the risk value of formaldehyde exposure level due to fish consumption in the community population in Dramaga Subdistrict with deterministic approach. Fish consumption data was obtained from a consumption survey using a semi food frequency questionnaire (FFQ). The fish consumption survey was conducted on 505 respondents with an age range of 5-60 years and over. Formaldehyde analysis was conducted on four types of fish that are popular and often consumed by the community, namely salted peda fish, salted anchovy rice fish, salted japuh fish, and fresh anchovy fish. The results showed that formaldehyde levels in four types of fish range from 8.30 – 105.09 mg/kg. The average daily consumption of salted peda, salted anchovy rice, salted japuh, and fresh anchovy was 11.58±8.32; 8.85±4.93; 7.72±4.51; and 9.85±6.45 (g/day). The average daily exposure values of formaldehyde in salted peda, salted anchovy rice, salted japuh, and fresh anchovy were 0.0025; 0.0088; 0.0146; and 0.0014 (mg/kg bw/day). The overall of daily exposure value is still below the maximum oral exposure limit of 0.2 (mg/kg bb/day). The value of exposure risk with hazard quotient (HQ) in four types of fish is 0.007–0.073. The HQ was found to be below 1, indicating risk level of exposure to formaldehyde in the community in Dramaga Subdistrict is still within safe limits.

Kadar Bioaktif dan Aktivitas Antioksidan Seduhan Kopi Arabika dengan Variasi Metode Penyeduhan Liguori, Christian; Giriwono, Puspo Edi; Herawati, Dian
Jurnal Mutu Pangan : Indonesian Journal of Food Quality Vol. 11 No. 1 (2024): Jurnal Mutu Pangan
Publisher : Department of Food Science and Technology (ITP), Faculty of Agricultural Technology, Bogor Agricultural University (IPB) in collaboration with the Indonesian Food and Beverage Association (GAPMMI), the National Agency of Drug and Food Control, and th

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jmpi.2024.11.1.11

Coffee contains abundant bioactive compounds related to health, among which are phenolic acids and diterpenes. This study aimed to investigate phenolic acids and diterpenes content in Arabica Gayo coffee, and its in-vitro antioxidant activities due to different brewing methods. The manual brewing methods used were tubruk (steeping), V60 drip, and hanging drip bag. The analysis conducted was determination of phenolic acid content as chlorogenic acid isomers (as 3-caffeoylquinic acid (3-CQA), 4-caffeoylquinic acid (4-CQA), and 5-caffeoylquinic acid (5-CQA)), diterpenes content (as cafestol and kahweol), and antioxidant activity using DPPH and FRAP method. The result showed that tubruk brew had 3-CQA, 4-CQA, and 5-CQA content of 0.38, 0.45, and 1.11 mg/mL, respectively, while V60 brew contained 0.39, 0.45, and 1.18 mg/mL, respectively. They were significantly higher than those in the drip bag, 0.25, 0.33, and 0.85 mg/mL, respectively. Cafestol and kahweol content in tubruk were significantly higher, reaching 3.03 and 7.86 mg/L consecutively, as in V60 were 0.40 and 1.02 mg/L and in drip bag were 0.46 and 0.85 mg/L. DPPH result displayed no significant difference per sample volume (918.45-921.17 mg ascorbic acid equivalent/L). FRAP result showed tubruk brew has the highest activity with 635.12 mg gallic acid equivalent/L, compared to V60 and drip bag brew at 560.91 and 551.10 mg gallic acid equivalent/L, consecutively. The results revealed that brewing methods affect the bioactive content of the final brew, in this research were phenolic acids and diterpenes. Various methods may differ in the variety and amount of other extracted bioactive compounds, so which affects the antioxidant activities of coffee brew.

Standar Mutu Cpo Untuk Minyak Makan dan Penerapan Cara Produksi Minyak Sawit Yang Baik Di Indonesia: Suatu Keniscayaan Andarwulan, Nuri; Hariyadi, Purwiyatno; Giriwono, Puspo Edi; Faridah, Didah Nur
Policy Brief Pertanian, Kelautan, dan Biosains Tropika Vol 4 No 1 (2022): Policy Brief Pertanian, Kelautan dan Biosains Tropika
Publisher : Direktorat Kajian Strategis dan Reputasi Akademik IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agro-maritim.0401.245-248

Minyak sawit merupakan komoditas non paling strategis di Indonesia. Ekspornya mendapatkan rintangan dikarenakan kandungan kontaminan 3 MCPDE dan GE yang tidak memenuhi syarat mutu sebagai ingredien pangan di Eropa. Kontaminan terbentuk sebagai hasil proses pemurnian yang menggunakan suhu tinggi dan terdapatnya precursor kontaminan. Senyawa prekursor kontaminan dan parameter mutu pada CPO yang menjadi faktor faktor pembentukan kontaminan belum menjadi standar CPO. Usulan standar mutu CPO untuk diproses minyak nabati dari sawit merupakan usulan baru . CPO yang memenuhi syarat mutu, dapat menghasilkan minyak makan dengan kandungan kontaminan memenuhi persyaratan mutu minyak nabati Eropa dan menjamin keamanan pangan untuk konsumen dalam negeri. CPO tersebut dapat diperoleh dengan penerapan Proses Pengolahan Minyak Sawit yang Baik. Panduan ini dapat mengadopsi CXC 79 2019. Sesuai penerapan PP No 86 tahun 2019,instansi yang terlibat dalam penyusunannya adalah Kementerian Pertanian, Kementerian Perindustrian dan BPOM dengan koordinasi oleh Kementerian Koordinator Bidang Perekonomian. Panduan ini dapat menjadi materi diplomasi perdagangan ekspor dan untuk diimplementasikan oleh industri sawit Indonesia.

Torbangun (Plectranthus amboinicus (Lour.) Spreng) Leaf Extract Upregulates Expression of Lactation-Related Genes in Human Mammary Epithelial Cells MCF-12A Tafzi, Fitry; Andarwulan, Nuri; Giriwono, Puspo Edi; Dewi, Fitriya N.
Indonesian Food Science and Technology Journal Vol. 8 No. 1 (2024): Volume 8 Number 1, December 2024 |IFSTJ|
Publisher : Department of Technology of Agricultural product (THP) Jambi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/ifstj.v8i1.37364

Torbangun (Plectranthus amboinicus (Lour). Spreng) leaf is a herbaceous plant capable of increasing breast milk, although the mechanism of bioactive compounds on the molecular level remains relatively unknown. Therefore, this study aimed to evaluate the effect of torbangun leaf extract on the expression of genes associated with alveologenesis and the formation of milk protein, namely prolactin receptor (PRLR), glucocorticoid receptor (GR), signal transducer, as well as activator of transcription 5A (STAT5A) and b-casein (CSN2). The result showed that the extract and fractions of torbangunleaf had IC50 values above 20 ug/ml against MCF-12A cells. Ethyl acetate fraction also enhanced the expression of gene GR, STAT5A, and CSN2. Water fraction of torbangun leaf enhanced expression of gene PRLR, GR, STAT5A, and CSN2. The bioactive compound was found to increase the expression of genes associated with proliferation, alveologenesis, and the formation of milk protein during gestation and lactation.

CONSUMPTION OF CARBONATED BEVERAGES AND THE RISK FOR GASTROINTESTINAL DISEASE: A SYSTEMATIC REVIEW Puspo Edi Giriwono; Nuri Andarwulan; Rimbawan Rimbawan; Deddy Muchtadi
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 37 No. 1 (2014)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v37i1.4010.69-76

ABSTRACTIssues of different effects of carbonated soft drinks to human health have been circulated and analyzed in both scientific and non-scientific approaches. However, there is few publications discussing the specific effect of carbonation on human health and, more often than not, studies have largely concentrated on the effect of sugar or calorie content in carbonated beverages in affecting our health. Thus the effect of carbonation itself on human health is then lost in arguments contradicting or reaffirming the effect of carbonated soft drinks. We conducted this systematic review to specifically observe current findings on the effect of carbonation in beverages on human health. This systematic review was conducted using Scirus search engine to list articles relevant with keywords such as CO2, carbonated beverage, carbonation, sparkling water, gastrointestinal, gastro-esophageal and adenocarcinoma. Next, articles were obtained from numerous databases and screened for their relevance and context. Finally, peer reading and discussion were conducted for the writing of this article. The results of this systematic review observed three major article subjects currently correlated with exclusive effect of carbonation on gastrointestinal health. Published studies indicate that oral cavity/dental health, gastro-esophageal reflux and most recently esophageal adenocarcinoma are discussed frequently and observed in population studies in different countries consuming significant quantities of carbonated beverages. Eight articles (40%) discussed dominant factors not correlated with carbonation which significantly affect dental erosions. Six (33%) articles observed no clear clinical significance carbonation promotes or exacerbate gastro-esophageal reflux. Interestingly, five (27%) articles reported insignificant correlation, even inversed, of carbonation on esophageal carcinoma.Currently available scientific studies on populations in multiple countries show that the effect of carbonation in beverages has non-significant (statistically) effect on the health of the gastrointestinal tract.Keywords: Carbonated beverages, gastrointestinal, GERD, esophageal adenocarcinoma*ABSTRAKIsu mengenai dampak karbonasi pada minuman ringan terhadap kesehatan, terutama kesehatan saluran pencernaan, telah banyak beredar beserta pembahasannya, baik secara ilmiah maupun tidak. Efek kesehatan dari unsur karbonasi pada minuman ringan sangat jarang dibahas dan dipublikasikan pada jurnal ilmiah. Melakukan systematic review status ilmiah terkini khusus mengenai dampak karbonasi dalam berbagai produk minuman terhadap kesehatan saluran pencernaan. Scirus search engine digunakan untuk melacak artikel ilmiah dengan kata kunci khusus, yakni CO2, carbonated beverage, carbonation, sparkling water, gastrointestinal, gastro-esophageal and adenocarcinoma. Tahap ini dilanjutkan dengan penapisan (screening) untuk kesesuaian subjek artikel dan akses. Tahap terakhir adalah focus group discussion bersama peer/ahli dalam bidang gizi, kesehatan dan keamanan pangan. Hasil dari systematic review memperlihatkan bahwa terdapat tiga kelompok pembahasan utama yang berhubungan dengan efek karbonasi terhadap kesehatan saluran pencernaan, yaitu kesehatan pada gigi/rongga mulut, refluks esofagus dan kanker esofagus. Hasil skrining menunjukkan 40 persen published articles membahas dental health, 33 persen membahas gastro-oestrophageal health dan 27 persen membahas esophageal adenocarcinoma. Delapan artikel yang membahas dental health menunjukkan erosi yang dapat terjadi disebabkan oleh faktor lain di luar karbonasi. Enam artikel yang membahas gastro-oestrophageal health menunjukkan tidak ada korelasi antara faktor karbonasi dengan refluks ataupun refluks kronis yang terjadi. Sementara 5 artikel memperlihatkan observasi yang berkorelasi terbalik dengan risiko munculnya kanker esofagus. Systematic review menunjukkan bahwa saat ini berbagai artikel ilmiah relevan yang sudah dipublikasikan menyimpulkan dampak karbonasi pada minuman terhadap kesehatan saluran pencernaan tidak signifikan secara statistik klinis. [Penel Gizi Makan 2014, 37(1): 69-76]Kata kunci: Minuman berkarbonasi, penyakit saluran pencernaan, GERD, esophageal adenocarcinoma

Co-Authors Afif Arwani Aliwikarta, Kuswanto Andi Nadya Tita Alia Andini Giwang Kinasih Antung Sima Firlieyanti Apon Zaenal Mustopa Apon Zaenal Mustopa Ayu Puspitalena RTR Betty Sri Laksmi Jenie Cesar Welya Refdi Christian Liguori, Christian Citta, Eleonora Pradnya Nirmala DAHRUL SYAH Dahrul Syah Dahrul Syah Deddy Muchtadi Dedi Fardiaz Dewi, Fitriya N. Dian Herawati Dias Erfan Dias Indrasti Eko Hari Purnomo Elsera Br Tarigan Elsera Br Tarigan, Elsera Br Endang Prangdimurti Enny Rimita Sembiring Farida, Eko Feri Kusnandar FITRY TAFZI Fransiska R. Zakaria Fransiska Rungkat FRANSISKA RUNGKAT ZAKARIA FRANSISKA RUNGKAT ZAKARIA Handayani, Yani Hanifah Nuryani Lioe Harsi D. Kusumaningrum Hartati Chairunnisa Hartuti, Wiwi Haryanto, Safira P.A Iftita Rakhma Ikrima Indrayana, Stefanus Kartika Sari Khaerul Fadly Kharisma Tamimi Kusmajadi Suradi Kusmajadi Suradi Kuswanto Aliwikarta Lidwina Lidwina Lilis Nuraida Maggy Thenawidjaja Suhartono Masayu Nur Ulfa Nasution, Zuraidah Noviana, Astrid Nugraha Edhi Suyatma Nur Wulandari Nuri Andarwulan Palupi, Nurheni Sri Pamungkas, Joko Purwiyatno Hariyadi Ratna Sari Listyaningrum Reni Koja Rimbawan , Rimbawan Rimbawan Rina Dias Agustin RTR, Ayu Puspitalena SARASWATI SARASWATI Sari Apriliana Satya Nugroho Sentani Chasfila Sri Yadial Chalid Stefanus Indrayana Suyanto Suyanto Tanaka, Darren Wahid Yulianto Wendry Setiyadi Putranto Wihardi, Alfin Maulana Winiati Pudji Rahayu Zakaria Zakaria

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