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All Journal HAYATI Journal of Biosciences Jurnal Pengolahan Hasil Perikanan Indonesia Jurnal Ilmu Tanah dan Lingkungan (Journal of Soil Science and Environment) VALENSI Jurnal Bios Logos CHEMISTRY PROGRESS JURNAL KIMIA SAINS DAN APLIKASI JURNAL TEKNOLOGI LINGKUNGAN IPTEK Journal of Proceedings Series Jurnal Riset Kimia SEMIRATA 2015 Jurnal Kimia Mulawarman IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Science and Technology Indonesia Jurnal Penelitian Sains Chimica et Natura Acta Indonesian Journal of Pure and Applied Chemistry Sains Natural: Journal of Biology and Chemistry JURNAL PERTANIAN PRESISI (JOURNAL OF PRECISION AGRICULTURE) Jurnal Tanah dan Iklim
Charlena
Departemen Kimia,Fakultas Matematika Dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor Kampus IPB Dramaga Jl.Agatis Wing 2 Level 4, Bogor 16144, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics

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Journal : JURNAL KIMIA SAINS DAN APLIKASI

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Synthesis and Characterization of Fluorapatite-Copper(II) Oxide with Sol-Gel Method as an Antibacterial Biomaterial Manasye Erlangga; Charlena Charlena; Irma Herawati Suparto
Jurnal Kimia Sains dan Aplikasi Vol 27, No 4 (2024): Volume 27 Issue 4 Year 2024
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.27.4.174-181

Abstract

One of the calcium phosphate compounds that can be used as an antibacterial material for coating dental implants is fluorapatite (FAp). This research aims to synthesize FAp at three different sintering temperatures (600, 800, and 1000°C), copper(II) oxide (CuO), and fluorapatite-copper(II) oxide (FAp-CuO) using the sol-gel method, and test the antibacterial properties of the synthesized products. The sol-gel technique proved successful in synthesizing FAp, with optimal results observed at a sintering temperature of 1000°C, achieving a crystallinity level of 90%. Analyses conducted using X-ray diffractometer, Fourier-transform infrared spectrometer, and scanning electron microscope-energy dispersive X-ray spectrometer revealed FAp as the dominating phase, exhibiting Ca/P and P/F ratios of 1.84 and 4.67, respectively. In FAp-CuO, replacing Ca2+ with Cu2+ ions lowered the average crystallite size, crystallinity, and Ca/P ratio. FAp, CuO, and FAp-CuO all displayed antibacterial activities against S. aureus and E. coli, with FAp-CuO having the maximum average inhibitory zone diameters of 0.243 and 1.397 mm, respectively.
Biodegradation of the Ciprofloxacin Antibiotic by White Rot Fungus Trametes hirsuta D7 Ananda Novita Hi Pattu; Charlena Charlena; Dede Heri Yuli Yanto; Irma Herawati Suparto; Maulida Oktaviani
Jurnal Kimia Sains dan Aplikasi Vol 27, No 12 (2024): Volume 27 Issue 12 Year 2024
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.27.12.590-596

Abstract

This study highlights the potential of fungal microorganisms, particularly Trametes hirsuta D7, in addressing antibiotic contaminants, such as ciprofloxacin, in the environment. The degradation process was conducted at room temperature over 7 days, and the results demonstrated that laccase was predominant in the degradation capacity; this was evidenced by the laccase enzyme activity levels obtained, namely 93 U/L, 120 U/L, and 130 U/L, compared to manganese peroxide activity of 7 U/L, 16 U/L, and 13 U/L at concentrations of 100, 300, and 500 mg/L, respectively. Notably, the laccase enzyme of T. hirsuta D7 exhibited significant degradation of ciprofloxacin, with high degradation rates of 64% at 100 mg/L, 48% at 300 mg/L, and 26% at 300 mg/L. This indicates that laccase from T. hirsuta D7 effectively degraded ciprofloxacin at various concentrations. Furthermore, this study revealed that ciprofloxacin did not significantly affect the growth of T. hirsuta D7. This suggests that microorganisms can survive and function effectively in the presence of antibiotic contamination without being impaired by these compounds. In conclusion, this study presents a potential solution for environmental antibiotic contamination by utilizing fungal microorganisms, particularly T. hirsuta D7, and their laccase enzymes. The findings of this study provide valuable insights for developing more environmentally sustainable and efficient degradation methods for antibiotic contamination in the ecosystem.
Co-Authors Aditya, Muhammad Hafizh Agung Dhamar Syakti Ahmad Syahreza Akhiruddin Akhiruddin Maddu Aldes Lebani Ananda Novita Hi Pattu Armi Wulanawati Aslihati Aslihati Chonny Damayanti Daniel Putra Oktavianus Laia Dede Heri Yuli Yanto Dicky Iswara, Muhammad Dila Ardiansyah Dyah Iswantini Fadila, Rina Fitriana Fendy, Fendy Hanies Ambarsari Henny Purwaningsih Ida Ayu Putu Sri Widnyani Irma Herawati Suparto Irma Herawati Suparto Irma Herawati Suparto Iswandi Anas Iswandi Anas Iswara, Muhammad Dicky J. SRI ADININGSIH Joni Prasetyo, Joni Khefanny, Yemima Chellyne Khofiyatuzziyadah, Alif Aryan Komar Sutriah L.I NURHAYATI LADY R. WIDOWATI Manasye Erlangga Marita Soebrata, Betty Mas?ud, Zainal Alim Maulida Oktaviani Moch. Irgham Zuhfria Moh. Yani Nazriati Nazriati dkk. Niken Dyah Wanodyanti Nurmawan, Cucu Putri Nurul Afiati Aflakhah Purwaningsih, Henny Purwantiningsih Ravena Ravena Rohma, Fitria Ainun Rosdiana, Tina S. SRI DWININGSIH Sari, Nurwita Mukti Setyanto Tri Wahyudi Sianipar, Rut Novalia Rahmawati Sulistioso Giat Sukaryo Susi Sulistia, Susi Tatang Hidayat Tetty Kemala Tina Rosdiana Wisaeni Intannia Wulan Islamia Yadi Setiadi Yadi Setiadi Yessie Widya Sari Zahra, Imelda Zainal Alim Mas'ud Zainal Alim Mas’ud