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All Journal Medicina Jurnal Kimia (Journal of Chemistry) Buletin Udayana Mengabdi Jurnal Farmasi Udayana E-Jurnal Medika Udayana Jurnal Veteriner ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico Bali Anatomy Journal
I Gusti Ayu Dewi Ratnayanti
Department Of Histology, Faculty Of Medicine, Udayana University, Bali, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Veterinary

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PROFIL KADAR KREATININ DAN ASAM URAT SEBAGAI PENANDA FUNGSI GINJAL PADA PENDUDUK LANSIA DI DESA KETEWEL I.N. Wande; I.G.A.D. Ratnayanti; I.G.K.N. Arijana; N.M. Linawati; P.P.A.P. Dewi
Buletin Udayana Mengabdi Vol 22 No 2 (2023): Buletin Udayana Mengabdi
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/BUM.2023.v22.i02.p06

Abstract

Background. Elderly is a group of population aged 46 years and over based on the age category according to the Ministry of Health of the Republic of Indonesia 2009. The function of the body's organs of the elderly population will decrease over time, especially kidney function. Several laboratory tests that can be used to assess kidney function are measuring the glomerular filtration rate or measuring levels of non-protein nitrogen such as creatinine and uric acid. Objectives. To determine kidney health in the elderly population in Ketewel Village by measuring blood creatinine and uric acid levels and providing education to keep the kidneys healthy. Implementation method. Elderly residents were given information about free kidney function tests, namely uric acid and blood creatinine, then directed to the Mantra Medika Clinical Laboratory for blood collection to avoid crowds due to the Covid-19 pandemic situation. Examination of blood creatinine and uric acid with the Erba XL100® device. Results. There were 22 elderly residents of Ketewel Village who did free creatinine and blood uric acid test. A total of 11 elderly men and 11 elderly women who participated in this program. The average age of the elderly who underwent examination was 59.95 ± 9.04 years. The mean systolic blood pressure was 127 ± 15 mmHg. The mean diastolic blood pressure was 76 ± 9.5 mmHg. The mean blood creatinine level was 0.95 ± 0.2 mg/dl. The average blood uric acid level was 5.42 ± 0.92 mg/dl. Conclusion. Free examination Creatinine and blood uric acid levels in the elderly population in Ketewel Village are within normal limits which can indicate kidney function of the elderly population is still within normal limits. Keywords: Creatinine, uric acid, elderly, Ketewel Villag
DISTRIBUSI GOLONGAN DARAH ABO-RH SISWA SDN 3 KETEWEL SUKAWATI GIANYAR N.M. Linawati; I.G.K.N. Arijana; I.N. Wande; I.W. Sugiritama; I.G.N.S. Wiryawan; I.G.A.D. Ratnayanti; I.A.I. Wahyuniari; D.A.A.S. Laksmi
Buletin Udayana Mengabdi Vol 21 No 4 (2022): Buletin Udayana Mengabdi
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/BUM.2022.v21.i04.p02

Abstract

Blood group is one of the identification parameters of a person's identity. Blood group is important to know in relation to medical and non-medical problems. However, there are still many blood group data that are not known to students in Ketewel village. This activity aims to determine the ABO-Rhesus blood group in children at SDN 3 Ketewel. The activity was carried out after coordinating with the Village Head, the headmaster of SDN 3 and also Mantra Medika Clinical Laboratory in Ketewel. Implementation of activities in August 2021 by complying with health protocols during the pandemic of Covid-19. The results of the activity were obtained as many as 65 students consisting of 35 male and 30 female which was 100% positive Rhesus. The distribution of ABO blood typing in male students was 14% A, 25% B, 62% O and 3% AB. Meanwhile, distribution of ABO blood type in female students is 13% A, 33% B and 47% O. From the activity, it can be concluded that the distribution of ABO-Rhesus blood group in SDN 3 Ketewel students is mostly O, the least blood group is AB which were all students Rhesus positive. Keywords: Identification, ABO-Rhesus blood group, SDN 3 Ketewel
MASKER GEL EKSTRAK KULIT MANGGIS MENCEGAH PENINGKATAN UKURAN KELENJAR SEBASEA KULIT TIKUS WISTAR YANG DIPAPAR SINAR UVB Arijana, I Gusti Kamasan Nyoman; Dewi Ratnayanti, I Gusti Ayu; Sri Wiryawan, I Gusti Nyoman; Dewi Wijayanti, Ni Putu Ayu
E-Jurnal Medika Udayana Vol 12 No 5 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i05.P10

Abstract

Kelemahan daya saing industri kosmetik estetik dalam negeri terhadap produk asing terutama disebabkan kurangnya data ilmiah mengenai efikasi produk untuk mendukung daya jualnya. Salah satu produk kosmetika yang sedang dikembangkan adalah masker gel ekstrak kulit manggis. Penelitian sebelumnya menunjukkan potensi masker ini untuk mencegah penuaan dini kulit akibat sinar matahari. Pada penelitian ini ingin diketahui pengaruhnya terhadap kelenjar sebaseus kulit. Rancangan penelitian eksperimental post test only control group dilakukan pada 27 tikus Wistar yang dipapar sinar UVB 840mJ selama 28 hari. Sampel dibagi ke dalam tiga kelompok, yaitu P0 (kontrol normal), P1 (dipapar sinar UVB dan dioles plasebo), dan P2 (dipapar sinar UVB dan dioles masker). Sampel kulit tikus kemudian diproses untuk pengecatan HE lalu ukuran kelanjar sebaseus dianalisis dengan software image raster. Setelah dilakukan analisis dengan anova satu jalan didapatkan perbedaan bermakna (p<0,05) ukuran kelenjar sebaseus antara kelompok P2 (11,51%) dengan kelompok P0 (3,77%) dan P1 (5,04%), sedangkan P0 dan P1 tidak menunjukkan perbedaan bermakna (p>0,05). Penelitian membuktikan bahwa masker gel ekstrak kulit manggis dapat mencegah peningkatan ukuran kelenjar sebasea akibat paparan sinar matahari. Kata kunci : pembesaran kelenjar sebaseus., UVB., penuaan kulit., masker gel kulit manggis
PENGARUH PEMBERIAN EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUS) SEBAGAI FITOESTROGEN TERHADAP STEATOSIS HEPAR TIKUS MODEL MENOPAUSE Hernowo, Elliana Freya; Arijana, IGK Nyoman; Sugiritama, I Wayan; Ratnayanti, IGA Dewi
E-Jurnal Medika Udayana Vol 12 No 6 (2023): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2023.V12.i06.P17

Abstract

Latar belakang: Wanita menopause akan mengalami penurunan hormon estrogen. Hormon estrogen diketahui memiliki sifat hepatoprotektif yang mampu mencegah terjadinya perlemakan pada hepar. Penurunan kadar estrogen bisa digantikan dengan senyawa fitoestrogen. Kulit buah naga merah (Hylocereus polyrhizus) diketahui memiliki banyak kandungan antosianin yang terbukti memiliki aktivitas sebagai fitoestrogen. Tujuan: Mengetahui adakah perubahan steatosis hepar tikus model menopause dengan pemberian ekstrak etanol kulit buah Hylocereus Polyrhizus. Metode: Penelitian ini merupakan penelitian randomized post-test control group design dengan menggunakan tiga kelompok sampel yang sudah melalui prosedur ovariektomi. Ketiga kelompok adalah kelompok P0 sebagai kontrol tanpa intervensi, P1 dengan intervensi ekstrak etanol kulit buah naga merah dosis 60mg/200grBB, dan P2 dengan intervensi ekstrak etanol kulit buah naga merah dosis 90mg/200grBB. Hasil: Didapatkan rerata jumlah sel steatosis per 100 sel hepar tikus model menopause pada kelompok P0, P1, dan P2 adalah 59,1259 ± 10,0087; 53,0435 ± 14,0674; 41,5001 ± 10,5814. Hasil One Way ANOVA menemukan adanya perbedaan yang bermakna dengan nilai p = 0,013. Hasil uji Post Hoc LSD menemukan perbedaan rerata antara kelompok P2 dengan P0 ditemukan bermakna (p = 0,004) dan P2 dengan P1 juga bermakna (p = 0,047). Sedangkan P0 dan P1 tidak bermakna (p = 0,247). Simpulan: Ekstrak etanol kulit buah Hylocereus Polyrhizus memiliki pengaruh terhadap steatosis hepar tikus model menopause. Didapatkan steatosis hepar terendah pada kelompok intervensi 90mg/200grBB. Kata kunci : Hylocereus polyrhizus, steatosis, menopause, fitoestrogen
Co-Authors A. A. D. Lestari Arijana, IGK Nyoman C.M.A. Putri, D.A.A.S. Laksmi Dewa Ayu Agus Sri Laksmi Dewi Wijayanti, Ni Putu Ayu Dinesh Tanabbal Dyta Putri Aryo Eswariy Chandramogan Fedik Abdul Ratam Gede Wirata Hernowo, Elliana Freya I A. G. Pradnyani I Dewa Ayu Eka Widiari Putri I Dewa Ayu Inten Primayanti I Dewa Gede Angga Triadi Nata I G. A. P. Y. Artha I Gusti Kamasan I Gusti Kamasan Arijana I Gusti Kamasan Nyoman Arijana I Gusti Ngurah Mayun I Gusti Nyoman Sri Wiryawan I Nyoman Wande I Wayan Sugiritama I.G.N.S. Wiryawan I.N. Wande I.W. Sugiritama Joshua Ezra Ronaldo Bayak K. Widnyani Astuti Komang Jegek Triangga Apsari Linawati N.M M.A. Wardhana Mayun G.N N. P. A. D. Wijayanti N.M. Linawati N.P.A.D. Wijayanti Ni Made Linawati Ni Made Mertaniasih Ni Nyoman Sri Budayanti Ni Putu Candra Paramita Ni Putu Sriwidyani NKA Maya Damayanti Nyoman Pratiwi Hapsari Dewi P.P.A.P. Dewi Ruthirar Kalaichelvam Tarvin Jit Singh Gill Yogarani V.C Rajappan Z. Aini,