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Agnis Pondineka Ria Aditama
Akademi Farmasi Jember
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Education of Diabetic Medication for Type 2 Diabetes Mellitus Patients and Their Families in Ledokombo Village, Jember Regency: Edukasi kepada Keluarga dan Penderita Diabetes Melitus Tipe 2 tentang Cara Penggunaan Obat di Desa Ledokombo, Kabupaten Jember Pondineka Ria Aditama, Agnis; Maulani, Dyan; Nafisah, Luthfiyah; Puspitasari, Anggraini; Agung Abdurrahman Wahid, Dimas; Nur Ramadhani, Alfi
Journal of Community Empowerment for Multidisciplinary (JCEMTY) Vol. 2 No. 1 (2024): May (2024)
Publisher : KHD Production

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53713/jcemty.v2i1.199

Abstract

Diabetes Mellitus (DM) is a disease characterized by an abnormal increase in blood sugar levels. The most frequently encountered type of DM is Diabetes Mellitus type 2. Type 2 DM is a condition that lasts a lifetime, so it has an impact on reducing the quality of human life. This happens because the body cannot produce and use insulin effectively so that sugar levels continue to increase. Type 2 DM is experienced by several people in Ledokombo Village, Jember Regency. Type 2 DM sufferers need to change their behavior, namely their eating patterns, taking medication and regular check-ups to manage their disease. The aim of this activity is to increase knowledge about how to use type 2 DM medication among the community in Ledokombo Village, Jember Regency. The method used is to provide education to families or type 2 DM sufferers about how to use the drug. The results of the activity show an increase in public knowledge and understanding of how to use type 2 DM medication. Knowledge before being given education shows the lowest value of 17.39% and the highest 100%, while after being given education shows the lowest value of 43.48% and the highest 100%. Increased public knowledge about how to using type 2 DM medication can provide motivation for healthy living to manage the disease.
Efek Induksi Proliferasi Sel Osteoblas Tulang Trabekular Mencit Jantan oleh Ekstrak Etanol 96% Daun Semanggi (Marsilea crenata Presl.): Induction Effect of Proliferation of Osteoblas Cells Trabecular Bone Male Mice by 96% Ethanol Extract of Semanggi Leaves (Marsilea crenata Presl.) Agnis Pondineka Ria Aditama; Faisal Akhmal Muslikh; Izza Nailia Shirvi; Firsta Roisatul Islamiyah; Kurniawan Hidayat Perdana Putra; Fidia Rizkiah Inayatilah; Weka Sidha Bhagawan; Burhan Ma’arif; Asri Wido Mukti; Asti Rahayu
Jurnal Sains dan Kesehatan Vol. 3 No. 4 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i4.634

Abstract

Osteoporosis adalah kondisi penurunan kepadatan mineral tulang dan berisiko patah tulang yang disebabkan oleh defisiensi estrogen. Fitoestrogen adalah senyawa pada tanaman yang memiliki kemampuan berikatan dengan reseptor estrogen untuk menggantikan fungsi estrogen. Daun M. crenata Presl. diketahui mengandung senyawa fitoestrogen. Tujuan penelitian ini adalah untuk membuktikan ekstrak etanol 96% daun M. crenata Presl. dapat meningkatkan jumlah sel osteoblas tulang trabekular femur dan vertebra pada mencit yang mengalami osteoporosis. Penelitian ini dilakukan dengan pemberian ekstrak etanol 96% daun M. crenata Presl. dosis 1,2; 2,4; 4,8; dan 9,6/20 g BB mencit/hari. Analisis dilakukan dengan cara pemeriksaan histomorfometri menggunakan pewarnaan HE, dan pengamatan sel osteoblas menggunakan mikroskop cahaya Olympus dengan software optilab. Data dianalisis menggunakan metode one way ANOVA. Hasil yang didapat yaitu kelompok PIV dengan dosis 9,6/20g BB mencit/hari dapat meningkatkan jumlah rerata sel osteoblas dengan nilai tertinggi yaitu 224,60 pada tulang trabekular femur dan 540,11 pada trabekular vertebra. Nilai perhitungan ED50 ekstrak etanol 96% daun M. crenata Presl. yaitu 1,908 mg pada tulang trabekular femur dan 2,878 mg pada tulang trabekular vertebra
Efek Penghambatan Ekspresi ER? Bebas oleh Fraksi n-Butanol Daun Semanggi (Marsilea crenata Presl.) pada Sel hFOB 1.19: Inhibitory Effect of Free-ER? Expression by n-Butanol Fraction of Semanggi (Marsilea crenata Presl.) Leaves on hFOB 1.19 Cells Burhan Ma’arif; Agnis Pondineka Ria Aditama; Faisal Akhmal Muslikh; Dewi Perwito Sari; Ira Purbosari; Hening Laswati; Mangestuti Agil
Jurnal Sains dan Kesehatan Vol. 3 No. 4 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i4.635

Abstract

Wanita pascamenopause dapat menyebabkan berbagai macam masalah kesehatan, diantaranya adalah osteoporosis yang diakibatkan karena gangguan produksi hormon estrogen dalam tubuh. Salah satu alternatif yang muncul dan berpotensi untuk menggantikan hormon estrogen adalah fitoestrogen. Daun M. crenata diketahui mengandung senyawa fitoestrogen. Tujuan dari penelitian ini adalah untuk mengetahui fraksi n-Butanol daun M. crenata dalam meningkatkan aktivitas osteoblas pada proses pembentukan tulang terhadap sel hFOB 1.19. Penelitian ini menggunakan metode ICC dengan bantuan instrumen CLSM. Penelitian ini dilakukan dengan pemberian fraksi n-Butanol dengan varian konsentrasi62,5; 125; dan 250 ppm, serta pemberian genistein sebagai kontrol positif pada sel hFOB 1.19. Hasil dari penelitian ini menunjukkan bahwa fraksi n-Butanol daun M. crenata memiliki kandungan senyawa estrogenik sebagai agen untuk meningkatkan aktivitas osteoblas melalui penurunan ekspresi ER? bebas sel hFOB 1.19 dan konsentrasi 62,5 ppm sebagai konsentrasi optimal dengan nilai ekspresi 594.108 AU.
Identification of The Chemical Compound from Ethyl Acetate and Ethanol Fraction of Banana Peel Extract (Musa Acuminata Colla) Hadi Barru Hakam Fajar, Siddiq; Denok Risky Ayu , Paramita; Agnis Pondineka Ria, Aditama; Rosida, Rosida
Indonesian Chimica Letters Vol. 4 No. 1 (2025)
Publisher : Department of Chemistry, Faculty of Mathematics and Natural Sciences, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/icl.v4i1.5688

Abstract

Bananas are broadly utilized as an alternative nourishment, whereas banana peels, as squander, are right now as it were utilized as creature nourish added additives. Banana peel contains flavonoids, saponins, glycosides, alkaloids, tannins, and catechins. Flavonoids are phenolic compounds (phenolic hydroxyl) that can act as cancer prevention agents and are by and large found in plants. This inquiry will recognize the chemical compounds of the ethyl acetic acid derivation division and the ethanol division of the banana peel extract (Musa acuminata Colla). This sort of investigation is a test research facility investigation with a Quasi-Experimental Plan investigate plan. In this consider, two sorts of fractionation were performed on the banana peel extract, specifically ethanol fractionation and ethyl acetate extraction fractionation. Besides, the formation of the fractionation was analyzed utilizing the LC-HRMS strategy. The comes about appears that the ethanol division of the banana peel extract contained different chemical compounds, including 4-methoxycinnamaldehyde, choline, and catechin. Within the ethyl acetic acid derivation division, the banana peel extract contained a few chemical compounds, including 5-hydroxymethyl-2-furaldehyde, diisobutylphthalate, and pyrogallol. These compounds appear in a huge region within the scope of HPLC-MS investigation.
Penyuluhan Pembuatan Gummy Candies Daun Kelor untuk Pencegahan Stunting di Desa Slateng Kabupaten Jember Mikhania Christiningtyas Eryani; Denok Risky Ayu Paramita; Agnis Pondineka Ria Aditama; Kukuh Judy Handojo
Jurnal Pengabdian UNDIKMA Vol. 4 No. 2 (2023): May
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v4i2.7457

Abstract

This service activity aims to increase the knowledge and skills of mothers in Slateng village, Jember, regarding making Moringa Leaves Gummy Candies to prevent stunting in toddlers. The method of implementing this service used interactive counseling. The instrument for evaluating this service was a questionnaire, which was analyzed descriptively, qualitatively, and quantitatively. The results of this service showed that the knowledge and skills of mothers as extension participants increased. It was evidenced by the data before the service process was carried out, the average participant knowledge was 66.25, and after the service was carried out, it became 70.62, so that there was a 4.37% increase in knowledge participants
Formulasi Dan Evaluasi Sifat Fisik Pasta Ekstrak Binahong (Anredera cordifolia (Ten) Steenis) Dan Cangkang Telur Ayam Dengan CMC Na Sebagai Pengikat Eryani, Mikhania Christiningtyas; Aditama , Agnis Pondineka Ria
Journal of Agropharmacy Vol. 1 No. 2 (2024)
Publisher : Faculty of Pharmacy, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/joa.v1i2.1265

Abstract

Binahong (Anredera cordifolia (Ten) Steenis) is a natural ingredient that can prevent tooth decay due to plaque. The purpose of this study was to formulate and evaluate the physical properties of binahong extract paste and chicken egg shells with various concentrations of CMC Na as a binder. The paste was formulated with various concentrations of CMC Na, namely 1.5% (F1), 2% (F2) and 2.5% (F3). The physical properties of the paste studied included organoleptic, homogeneity, pH, viscosity, spreadability and foam height. The results showed that variations in the concentration of CMC Na affected the organoleptic physical properties of color, viscosity and foam height of the paste. However, variations in the concentration of CMC Na had no effect on the pH and spreadability of the paste.
Co-Authors Agung Abdurrahman Wahid, Dimas Anies Rohman Dwijayanti Asri Wido Mukti Asti Rahayu Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Denok Risky Ayu , Paramita Denok Risky Ayu Paramita Efyn Novianti Putri Eryani, Mikhania Christiningtyas Faisal Akhmal Muslikh Fidia Rizkiah Inayatilah Firsta Roisatul Islamiyah Hadi Barru Hakam Fajar Siddiq Hening Laswati Putra Izza Nailia Shirvi Kukuh Judy Handojo Kurniawan Hidayat Perdana Putra Mangestuti Agil Maulani, Dyan Nafisah, Luthfiyah Nur Ramadhani, Alfi Purbosari, Ira Puspitasari, Anggraini Rosida Rosida Sari, Dewi Perwito Weka Sidha Bhagawan