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Riga Riga
Universitas Negeri Padang
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JAMUR ENDOFITIK BS-1 DARI BUNGA SAMBILOTO (Andrographis paniculata) PADA MEDIA PERTUMBUHAN KACANG HIJAU: SKRINING FITOKIMIA DAN AKTIVITAS ANTIOKSIDAN Aisyah, Siti; Oktria, Wandi; Silvani, Mauline Adia; Riga, Riga
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 13 No 2 (2024): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v13i2.319

Abstract

Sambiloto (Andrographis paniculata) is a medicinal plant in the Acanthaceae family. A. paniculata is known to synthesize active compounds with potent antioxidant properties that effectively hinder the activity of free radicals. Further studies of the antioxidant activity of this plant can be elaborated using its endophytic fungi. This research aims to analyze phytochemicals and measure the antioxidant activity (IC50) of the endophytic fungus BS-1 in flower of sambiloto. The results of the phytochemical screening of the ethyl acetate extract (EtOAc) of the BS-1 endophytic fungus were declared positive for containing steroid, terpenoid, phenolic and alkaloid compounds. The antioxidant test results indicated a very strong free radical inhibition ability with an IC50 value = 34.61 ppm.
Skrining Fitokimia dan Uji Aktivitas Antioksidan Jamur AS-3 yang Diisolasi dari Akar Sambiloto: Phytochemical Screening and Antioxidant Activity of Fungus AS-3 Isolated from The Root of Sambiloto Riga, Riga; Dewita, Febby Octavia; Yuranda, Fitri; Agustini, Dewi Meliati; Sagia, Randi
Jurnal Sumberdaya Hayati Vol. 11 No. 2 (2025): 2025
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.11.2.49-54

Abstract

Sambiloto, often referred to as the “Raja Pahit”, is a plant belonging to the Acanthaceae family. This plant is known to produce secondary metabolite compounds with various biological benefits, including antioxidant properties. Antioxidant compounds have been shown to counteract the formation of free radicals that are harmful to the body. The antioxidant activity of the Sambiloto plant can be evaluated using endophytic fungi associated with it. This study aimed to identify secondary metabolite compounds and evaluate the antioxidant activity of AS-3 Fungus isolated from the Sambiloto roots. Phytochemical analysis revealed that the ethyl acetate extract of AS-3 contained terpenoids, flavonoids, and alkaloids. In addition, the antioxidant activity test showed promising results, with an IC50 value of 10.225 ppm, indicating high antioxidant potential. This is the first report on the phytochemical screening and antioxidant activity test of the ethyl acetate extract of AS-3 fungus isolated from Sambiloto roots.
Co-Authors Adia Silvani, Mauline Agustini, Dewi Meliati Ahmad Raisan R.P Anes Vanesa Bali Yana Fitri Desi Kurniawati Desy Kurniawati DESY KURNIAWATI Desy Kurniawati Dewi Meliati Agustini Dewita, Febby Octavia Dina Agustina Dwi Rahma Doni, Deani Edi Nasra Edwina Zainal Euis Holisotan Hakim Eva Selviana Fajriah Azra Ferdi Henfi Pratama Firda Febria Iryani Iryani Isra Yeni Khairiyah, Ghina Luqiyatur Rohmah M. Iqbal S.G MARIAM ULFAH ULFAH Mauline Adia Silvani Mauline Adia Silvani Melisa Yolanda Muhammad Habibul Ikhsan Muhammad Habibul Ikhsan Mulia, Melindra Nur Meisinca, Dzulhijjah Oktavia Dewita, Febby Oktria, Wandi Rafigha Gusjelita Absa Rani Aulia Suhanah Rani Aulia Suhanah Rizka Purwanti Romy Dwipa Yamesa Away Sagia, Randi Sari Purbaya Silvani, Mauline Adia Siti Aisyah Sri Benti Etika Sukma Amelia Suryani, Okta Suryelita . Syamsi Aini Syamsi Aini Tessa Faradilla Trisna Kumala Sari Varel Anshar Al Khairi Wandi Oktria Yeni, Isra Yuranda, Fitri Yusnita, Rani Zonalia Fitriza