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All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Ilmu Kefarmasian Indonesia Majalah Farmasetika Indonesian Journal of Dental Medicine Sinnun Maxillofacial Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Enrichment: Journal of Multidisciplinary Research and Development
Surboyo, Meircurius Dwi Condro
Faculty Of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Engineering Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Knowledge and perception of dental profession students about the selection of mouthwash for recurrent aphthous stomatitis (RAS) therapy Ayuningtyas, Nurina Febriyanti; Surboyo, Meircurius Dwi Condro; Nagoro, Ayu Anggraini Broto; Hendrayanto, Shalma Maulidya; Rachmadanti, Zhafira Khansa
Enrichment: Journal of Multidisciplinary Research and Development Vol. 2 No. 9 (2024): Enrichment: Journal of Multidisciplinary Research and Development
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/enrichment.v2i9.236

Abstract

Recurrent aphthous stomatitis (RAS) is a recurring ulcer on the oral mucosa with no known cause and without association with systemic diseases. Dental profession students are expected to have adequate knowledge and positive perceptions regarding the use of mouthwash for RAS therapy. This study aimed to describe the levels of knowledge and perception of dental students about the selection and use of mouthwash for managing RAS. The study involved 90 students from the Dental Profession Study Programme at the Faculty of Dental Medicine, Universitas Airlangga, Surabaya. Data were collected through an online questionnaire comprising 18 questions, divided into two categories: (1) knowledge of mouthwash brands, active ingredients, usage duration, and timing, and (2) perceptions regarding the importance, safety, and effectiveness of mouthwash for RAS. The responses were tabulated and presented in percentages. The results revealed that 95.56% of respondents demonstrated good knowledge of mouthwash for RAS therapy. Perceptions of the importance, safety, and effectiveness of mouthwash were 87.78%, 98.89%, and 94.44%, respectively, with an overall positive perception rate of 92.22%. In conclusion, dental profession students at Universitas Airlangga possess a high level of knowledge and positive perceptions about the use of mouthwash for RAS therapy.
Effect of freeze-dried platelet-rich plasma on FGF-2 and type I collagen expression in traumatic ulcers of diabetes mellitus: An in vivo study Riskayanti, Ni Putu; Radithia, Desiana; Maharani, Annissaqiella; Hendarti, Hening Tuti; Rahayu, Retno Pudji; Surboyo, Meircurius Dwi Condro; Ernawati, Diah Savitri
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p361-366

Abstract

Background: Diabetes mellitus is a chronic disease characterized by the pancreas’s inadequate production of insulin or the body’s impaired utilization of insulin, resulting in dysregulation of blood sugar levels. Diabetes mellitus causes prolonged wound healing due to decreased growth factors, including fibroblast growth factor 2 (FGF-2) and type I collagen. Purpose: This research analyzes the effect of topical administration of freeze-dried platelet-rich plasma (FD-PRP) on the healing process of traumatic ulcers in diabetic Wistar rats by increasing FGF-2 and type I collagen expression. Methods: Allogenic FD-PRP was obtained from the blood of 35 Wistar rats and 2% carboxymethyl cellulose (CMC) was added to make a gel formulation. Diabetes was induced in 30 Wistar rats using streptozotocin, followed by the creation of traumatic ulcers on the lower labial mucosa using a hot burnisher. The traumatic ulcers were then topically treated with FD-PRP gel in the treatment group and 2% CMC gel in the control group. Analysis of FGF-2 and type I collagen expression was performed through indirect immunohistochemical methods following treatment for 3, 5, and 7 days. Results: The expression of FGF-2 and type I collagen in the FD-PRP was higher than in the control group (p < 0.05). Conclusion: Topical application of FD-PRP plays an important role, especially in increasing the FGF-2 and type 1 collagen expression, in the healing process of traumatic ulcers in diabetic Wistar rats.
Oral field cancerization: Genetic profiling for a prevention strategy for oral potentially malignant disorders Puspasari, Karlina; Pasaribu, Togu Andrie Simon; Surboyo, Meircurius Dwi Condro; Ayuningtyas, Nurina Febriyanti; Santosh, Arvind Babu Rajendra; Ernawati, Diah Savitri
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p189-196

Abstract

Background: Oral cancer therapy, such as radiation or surgical treatment, has pernicious long-term effects that patients suffer throughout their life, the disability being considerable with delayed diagnosis. It is well known that many oral cancers develop from oral potentially malignant disorders (OPMDs). Patients diagnosed with OPMDs may have an increased risk of developing cancer anywhere in the oral cavity. Early detection and intervention could be essential prevention strategies to inhibit oral cancer progression. OPMDs may not immediately develop into carcinoma. However, this condition provides a "field” of specific abnormalities wherein evolving altered genetic cells can be explained with the "field cancerization” concept. Purpose: This review aims to describe the "field cancerization” concept in oral cancer and OPMD, which is expected to contribute to a better clinical management strategy for oral cancer prevention. Review: "Oral field cancerization” describes oral cancers that develop in multifocal areas of pre-cancerous changes. It can be found as histologically abnormal tissue surrounding the tumor, suggesting that oral cancer often consists of multiple independent lesions. Conclusion: The oral field cancerization concept should prompt healthcare professionals to remind their patients that frequent oral examination with histological studies and molecular testing is mandatory for those at high risk of developing malignancies.
Co-Authors Adiastuti Endah Parmadiati Anita Lukman Anita Lukman Ari Hapsari Tri Wardani BENNI ISKANDAR Chitipothu, Mani Deepthi Daniel Happy Putra Desiana Radithia, Desiana Desvia Nuzela Qurzani Hariyadi Diah Savitri Ernawati Fatma Yasmin Mahdani Femilian, Afryla Hendrayanto, Shalma Maulidya Hening Tuti Hendarti Imanu, Sherina Fatwa Ira Arundina Kuntardjo, Yuhanna Leginis, Shinadilla Naza Leny Leny Leny Leny Leny, Leny Maharani, Annissaqiella Nagoro, Ayu Anggraini Broto Nurina Febriyanti Ayuningtyas Okla Elfitri Pasaribu, Togu Andrie Simon Pratiwi, Aulya Setyo Puspasari, Karlina Puspitasari, Yeni Rachmadanti, Zhafira Khansa Raesa Tartilla Raesa Tartilla Retno Pudji Rahayu Riskayanti, Ni Putu Rona Syafira Safri Safri Safri Safri Saka Winias Santosh, Arvind Babu Rajendra Septi Muharni Sismiyanti, Rossy Sivanandham, Shamala Ummer, Hiba Winda Dwi Malinda Masuku