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Hubungan Tingkat Pengetahuan Terhadap Sikap Orang dengan HIV/AIDS pada Oral Hairy Leukoplakia dan Kandidiasis Oral Radithia, Desiana; Ernawati, Diah Savitri; Surboyo, Meircurius Dwi Condro; Ayuningtyas, Nurina Febriyanti; Mahdani, Fatma Yasmin; Pratiwi, Aulya Setyo; Sismiyanti, Rossy; Kuntardjo, Yuhanna; Puspitasari, Yeni
Sinnun Maxillofacial Journal Vol. 6 No. 02 (2024): Oktober 2024
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/smj.v6i02.128

Abstract

Pendahuluan: HIV/AIDS telah menjadi masalah kesehatan masyarakat global. Infeksi HIV dapat menyebabkan gangguan kekebalan tubuh dan bermanifestasi di beberapa tempat baik secara sistemik maupun di rongga mulut. Manifestasi oral yang paling umum terkait dengan HIV/AIDS adalah Kandidiasis Oral dan Oral Hairy Leukoplakia. Sebagai orang yang hidup dengan HIV/AIDS (ODHIV) mungkin menemukan manifestasi tersebut, pengetahuan mereka dapat menentukan sikap mereka terhadap temuan tersebut.Tujuan Penelitian: Mengamati sikap ODHIV di kota Surabaya terhadap dua manifestasi oral HIV yang paling umum ditemukan, yaitu Oral Hairy Leukoplakia dan Kandidiasis Oral, serta menentukan hubungan antara pengetahuan dan sikap mereka terhadap hal tersebut. Bahan dan Metode: Sebanyak 30 responden diberikan kuesioner untuk menilai pengetahuan dan sikap mereka mengenai Oral Hairy Leukoplakia dan Kandidiasis Oral. Pengetahuan didefinisikan dengan kriteria baik, cukup, dan rendah. Sikap didefinisikan sebagai positif, netral, dan negatif. Hasil: Tingkat pengetahuan mengenai Oral Hairy Leukoplakia dan Kandidiasis  Oral menunjukkan hasil tinggi (33%), sedang (54%) dan rendah (13%). Responden menunjukkan sikap positif (30%) dan sikap tidak setuju (27%), sedangkan netral (43%). Terdapat hubungan positif yang signifikan antara tingkat pengetahuan responden dengan sikap mereka (p = 0,46). Kesimpulan: Terdapat hubungan antara pengetahuan yang baik dengan sikap positif pada masyarakat.
Knowledge and perception of dental profession students about the selection of mouthwash for recurrent aphthous stomatitis (RAS) therapy Ayuningtyas, Nurina Febriyanti; Surboyo, Meircurius Dwi Condro; Nagoro, Ayu Anggraini Broto; Hendrayanto, Shalma Maulidya; Rachmadanti, Zhafira Khansa
Enrichment: Journal of Multidisciplinary Research and Development Vol. 2 No. 9 (2024): Enrichment: Journal of Multidisciplinary Research and Development
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/enrichment.v2i9.236

Abstract

Recurrent aphthous stomatitis (RAS) is a recurring ulcer on the oral mucosa with no known cause and without association with systemic diseases. Dental profession students are expected to have adequate knowledge and positive perceptions regarding the use of mouthwash for RAS therapy. This study aimed to describe the levels of knowledge and perception of dental students about the selection and use of mouthwash for managing RAS. The study involved 90 students from the Dental Profession Study Programme at the Faculty of Dental Medicine, Universitas Airlangga, Surabaya. Data were collected through an online questionnaire comprising 18 questions, divided into two categories: (1) knowledge of mouthwash brands, active ingredients, usage duration, and timing, and (2) perceptions regarding the importance, safety, and effectiveness of mouthwash for RAS. The responses were tabulated and presented in percentages. The results revealed that 95.56% of respondents demonstrated good knowledge of mouthwash for RAS therapy. Perceptions of the importance, safety, and effectiveness of mouthwash were 87.78%, 98.89%, and 94.44%, respectively, with an overall positive perception rate of 92.22%. In conclusion, dental profession students at Universitas Airlangga possess a high level of knowledge and positive perceptions about the use of mouthwash for RAS therapy.
Effect of freeze-dried platelet-rich plasma on FGF-2 and type I collagen expression in traumatic ulcers of diabetes mellitus: An in vivo study Riskayanti, Ni Putu; Radithia, Desiana; Maharani, Annissaqiella; Hendarti, Hening Tuti; Rahayu, Retno Pudji; Surboyo, Meircurius Dwi Condro; Ernawati, Diah Savitri
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p361-366

Abstract

Background: Diabetes mellitus is a chronic disease characterized by the pancreas’s inadequate production of insulin or the body’s impaired utilization of insulin, resulting in dysregulation of blood sugar levels. Diabetes mellitus causes prolonged wound healing due to decreased growth factors, including fibroblast growth factor 2 (FGF-2) and type I collagen. Purpose: This research analyzes the effect of topical administration of freeze-dried platelet-rich plasma (FD-PRP) on the healing process of traumatic ulcers in diabetic Wistar rats by increasing FGF-2 and type I collagen expression. Methods: Allogenic FD-PRP was obtained from the blood of 35 Wistar rats and 2% carboxymethyl cellulose (CMC) was added to make a gel formulation. Diabetes was induced in 30 Wistar rats using streptozotocin, followed by the creation of traumatic ulcers on the lower labial mucosa using a hot burnisher. The traumatic ulcers were then topically treated with FD-PRP gel in the treatment group and 2% CMC gel in the control group. Analysis of FGF-2 and type I collagen expression was performed through indirect immunohistochemical methods following treatment for 3, 5, and 7 days. Results: The expression of FGF-2 and type I collagen in the FD-PRP was higher than in the control group (p < 0.05). Conclusion: Topical application of FD-PRP plays an important role, especially in increasing the FGF-2 and type 1 collagen expression, in the healing process of traumatic ulcers in diabetic Wistar rats.