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The potency of water leaves extract of bay (Syzygium polyanthum) and papaya (Carica papaya) as larvacides to filaria vector Culex queinquefasciatus (Diptera: Culicidae) Vella Rohmayani; Anindita Riesti Retno Arimurti; Rinza Rahmawati Samsudin
Bioma : Jurnal Ilmiah Biologi Vol. 11 No. 2: October 2022
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/bioma.v11i2.10587

Culex quenquefasciatus is a mosquito that acts as a vector of filariasis disease. In Indonesia filariasis is still one of the endemic diseases. This proves that the handling of vector Culex quenquefasciatus is still not done optimally. One way that can be done to control mosquito vectors one of them is to use larvacide. Larvacide which is widely used today is still synthetic. Although very efficient in causing mosquito mortality, larvacide synthesis harms the environment and can cause vectors resistance. Then another larvacide alternative is needed that is effective and does not cause negative effects. Plants can be a choice of larvacide from nature. The study aims to find out the potential of the water extract of bay leaves and papaya leaves in killing the larvae of the Cx. quenquefasciatus mosquito as well as the value of LC50 after 24-hour observation. The type of research used is experimental research. The concentration of the water extract of bay leaves and papaya leaves used is 10%, 30%, 50%, 70%, and 90% with trhee times replication. LC50 is calculated using the Finney formula (1971), the calculation is carried out using application SPSS statistical version 26. Based on the research conducted, the value of bay leaf water extract LC50 = 62.89 g/ml and papaya leaf water extract LC50 = 45.10 g/ml. So based on the LC50 value, ita can be concluded that papaya leaf water extract is more effective in causing mortality Cx. quenquefasciatus compared with bay leaf water extract.

Aktivitas Antioksidan Kulit Jeruk Pacitan (Citrus sinensis L.) Terhadap Kadar SGOT dan SGPT Rattus norvegicus Dengan Paparan Logam Berat Timbal (Pb) Baterun kunsah; Rinza Rahmawati Samsudin
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 7, No 3 (2022)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v7i3.60184

Timbal merupakan logam yang bersifat toksik apabila terakumulasi di dalam tubuh dalam jumlah tertentu. Timbal masuk ke dalam sirkulasi darah dan beresiko menyebabkan kerusakan hati dimana dapat dilihat dengan pemeriksaan SGOT dan SGPT. Pada kondisi stres oksidatif dapat mengakibatkan terjadinya kerusakan sel hati sehingga tubuh memerlukan antioksidan eksogen, yang bisa didapatkan dari ekstrak kulit jeruk pacitan. Tujuan penelitian adalah untuk mengetahui pengaruh pemberian Ekstrak kulit jeruk pacitan pada kadar SGOT dan SGPT Rattus norvegicus wistar yang diinduksi dengan menggunakan timbal asetat. Metode penelitian ini adalah quasi experimental dengan rancangan post test only control group design. Sampel dibagi menjadi 5 kelompok yaitu Kelompok (G1) Rattus norvegicus diberi ransum pakan standar dan aquadest; (G2) diberikan Pb asetat peroral 30 mg/kgBB/hari, (G3) diberikan Pb asetat peroral 30 mg/kgBB/hari dan ekstrak kulit jeruk pacitan dosis 100 mg/kgBB/hari; (G4) diberikan Pb asetat peroral 30 mg/kgBB/hari dan ekstrak kulit jeruk pacitan dosis 200 mg/kgBB/hari; (G5) diberikan 30 mg/kgBB/hari dan ekstrak kulit jeruk pacitan dosis 300 mg/kgBB/hari. Penelitian telah mendapatkan surat keterangan layak etik No.EA/KEPK-Poltekkes_Sby/V/2022. Hasil penelitian berupa besar prosentase penurunan kadar SGOT dari kelompok G2 dengan kelompok perlakuan G3, G4 dan G5 yaitu 16%, 33%, dan 57%. Sedangkan untuk hasil penurunan kadar SGPT dari kelompok G2 dengan kelompok perlakuan G3, G4 dan G5 yaitu 25%, 34%, 46%. Kesimpulan ekstrak kulit jeruk pacitan memberikan pengaruh yang signifikan terhadap kadar SGOT dan SGPT pada Rattus norvegicus yang diinduksi PbCH3COO dengan nilai signifikasi < 0,005.

Edukasi Dan Pelayanan Pemeriksaan Infeksi Jamur Kulit Pada Pekerja Kebersihan Universitas Di Surabaya Anindita Riesti Retno Arimurti; Fitrotin Azizah; Dita Artanti; Rinza Rahmawati Samsudin; Yeti Eka Sispita Sari; Nur Vita Purwaningsih; Vella Rohmayani; Ellies Tunjung Sari Maulidiyanti
Empowerment: Jurnal Pengabdian Masyarakat Vol. 2 No. 1 (2023): JANUARI 2023
Publisher : Pusat Riset Manajemen dan Publikasi Ilmiah Serta Pengembangan Sumber Daya Manusia Sinergi Cendikia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55983/empjcs.v2i1.361

Work that requires being in a humid area, can cause fungal infections. Skin fungal infections in humans can be divided into two, namely dermatophytosis and non-dermatophytosis. Dermatophytosis is a superficial fungal infection that attacks the keratinized parts of the skin, nails and hair and is caused by 3 genera, namely Microsporum, Epidermophyton, and Trichophyton. While non dermatophytosis is a fungal infection of the outer skin or this type of fungal infection does not reach the keratin tissue. Non-dermatophyte fungi include Aspergillus sp., Malessezia furfur. Due to dermatophyte and non-dermatophyte fungal infections, namely itching of the skin or earlobe. This activity aims to increase the understanding of cleaning workers at one of the universities in Surabaya about the dangers of fungus on the skin, so that they can prevent and anticipate early spread. The method used in this community service activity is the presentation and discussion of the dangers of skin fungal infections. To measure the level of understanding of the participants regarding the dangers of toxoplasmosis, a pretest was conducted at the beginning and at the end of the activity. This activity was attended by 22 janitors, both male and female. The average pretest score is 49,63 points, while the average posttest score is 71,48 points. These results indicate that there is an increase in the knowledge of cleaning workers at one of the universities in Surabaya about the causes, dangers, modes of transmission and methods of preventing skin fungal diseases. Educational activities are expected to be sustainable so that the community can apply steps to prevent skin fungal infections.

Hubungan Konsumsi Ikan Laut Terhadap Kadar Kolestrol Total Pada Nelayan Di Desa Tamberu Timur Waras Budiman; Ellies Tunjung S. Maulidiyanti; Rahma Widyastuti; Rinza Rahmawati Samsudin
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 7 No 1 (2024): The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v7i1.23602

Konsumsi ikan laut yang mempunyai kandungan yang kaya akan protein dan omega-3 serta berkualitas tinggi dan bagus bagi kesehatan, akan tetapi jika mengkonsumsi secara berlebihan dapat menyebabkan lemak jenuh serta dapat meningkatkan kadar kolesterol yang tinggi. Tiap harinya nelayan menghasilkan ikan, hasil tangkapan itu sebagian dijual dan sebagian dikonsumsi sehari-hari. Berdasarkan hasil wawancara dengan nelayan, mereka bekerja sebagai nelayan dalam waktu lebih dari 5 tahun. Kebiasaan nelayan tersebut yaitu tiap hari mengkonsumsi ikan hasil tangkapan, sebanyak lebih dari 3 kali dalam sehari. Tujuan penelitian ini adalah untuk mengetahui hubungan konsumsi ikan laut dengan kadar kolesterol total pada nelayan di desa tamberu timur. Metodeyang digunakan yaitu metode kuantitatif dengan jenis penelitian observasional analitik dengan desain cross sectional. Populasi yang dalam penelitian ini adalah nelayan di Desa Tamberu Timur. Teknik sampling yang digunakan pada penelitian ini adalah menggunakan probability sampling didapatkan 33 responden yang memenuhi syarat kriteria inklusi dan eksklusi. Hasil yang didapat kadar kolesterol yang tinggi yaitu terdapat 20 responden (60.7%), sedangkan kadar kolesterol yang normal sebanyak 13 orang (39.3%). Setelah dilakukan analisis data dengan SPSS didapatkan hasil kadar kolesterol sebesar 0,005< 0,05 sehingga dapat disimpulkan bahwa H1 diterima yang berarti terdapat hubungan antara mengkonsumsi ikan laut dengan kadar kolesterol pada nelayan di Desa Tamberu Timur. Kata kunci : Kolestrol total, Konsumsi Ikan laut

The Effect of Storage Time for Pooled Sera on Freezers on the Quality of Clinical Chemical Examination: Pengaruh Lama Penyimpanan Pooled Sera pada Freezer Terhadap Mutu Pemeriksaan Kimia Klinik Maulidiyanti, Ellies Tunjung Sari; Purwaningsih, Nur Vita; Widiyastuti, Rahma; Samsudin, Rinza Rahmawati; Arimurti, Anindita Riesti Retno
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1613

A common problem in clinical laboratories is maintaining the stability of serum analytes during sample storage. Samples are usually stored in the door (4–8°C) of the refrigerator for a short period of time or in the freezer (-20°C) for a longer period of time (pre-analytical stage) and subsequently, during post-analysis sample handling (storage time and temperature). This study aims to analyze the stability in this case is the storage time of pooled sera in the freezer at temperatures up to -18º C and in the refrigerator at temperatures up to 4°C for 3 months with the inspection parameters, namely cholesterol and triglycerides. This type of research is experimental, with a research design that is time series control group design. The sample in this study was a control serum in the form of pooled sera stored in the freezer and refrigerator which was checked for cholesterol and triglyceride levels every 2 weeks for 3 months or for 12 weeks. The results showed that the average calculation of cholesterol levels in pooled sera stored in the freezer was 142.07 mg/dL and the average cholesterol level examination stored in the refrigerator was 161.89 mg/dL then the average the examination of triglyceride levels in pooled sera stored in the freezer is 112.89 mg/dL and the average examination of triglyceride levels stored in the refrigerator is 140.46 mg/dL. Based on the analysis of the research results, it can be concluded that, there is an effect of storage time in the freezer on the stability of cholesterol levels and triglyceride levels.

Kadar Glukosa Darah Pada Pasien Covid-19 Lanjut Usia Widyastuti, Rahma; Tunjung, Ellies Tunjung; Purwaningsih, Nur vita; Samsudin, Rinza Rahmawati
Indonesian Academia Health Sciences Journal Vol 4 No 1 (2023): Indonesian Academia Health Sciences Journal
Publisher : Universitas Muhammadiyah Surabaya

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COVID-19 (Coronaviruses Disease 2019) is a disease caused by a new type of corona virus, namely Sars-CoV-2, was first reported in Wuhan, China on December 31 2019. The death rate in elderly patients continues to increase, accounting for 21.9% . COVID-19 risk assessments show that assessing blood glucose levels has the potential to better identify people at risk of adverse outcomes. Blood sugar levels are affected by a number of factors, including gender and age. At this point, elderly patients experience many physical and mental changes, especially the decline in individual functions and abilities in general. This study aims to describe the results of examining blood glucose levels in elderly COVID-19 patients at Brawijaya Hospital, Surabaya. This type of research is descriptive research with secondary data from the laboratory using total sampling technique. The sample in this study were 65 elderly patients who tested positive for COVID-19 who had blood glucose checked at the clinical pathology laboratory in the September- December 2020 period at Brawijaya Hospital, Surabaya. Variables are then grouped and then tabulated and displayed descriptively in percentage form. The results of this study were obtained from 65 elderly COVID-19 patients who had normal fasting blood glucose levels (<100 mg/dl) which was 6.15%, while those who had abnormal glucose levels (>100 mg/dl) were 93.85%. . These results indicate that the majority of elderly COVID-19 patients have abnormal blood glucose levels

Analisis Siklamat Berbagai Merk Kopi Sachet Yang Di Jual Di Pasar Keputih Surabaya Kartikorini, Nastiti; Ariana, Diah; Samsudin, Rinza Rahmawati; Mardiyah, Siti; Kunsah, Baterun
Indonesian Academia Health Sciences Journal Vol 4 No 1 (2023): Indonesian Academia Health Sciences Journal
Publisher : Universitas Muhammadiyah Surabaya

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Coffee is a type of plant that contains caffeine and can be processed into a delicious drink. In the process of making coffee usually used artificial sweeteners and natural sweeteners. People prefer artificial (synthetic) sweeteners because they are relatively cheap and easy to obtain. The artificial sweetener that is often used by traders is cyclamate. Cyclamate is highly soluble in water and has a sweetness level of 30 times that of sugar. According to research conducted by Indoforum, 2008 in Sebayang, et.al. 2015, Artificial sweeteners (cyclamate) can have negative effects on human health. This study aims at Cyclamate Analysis of Various Brands of Coffee Sachets Sold at Pasar Keputih Surabaya. This type of research is descriptive with a total sample of 30 samples, with qualitative analysis. Using the deposition reaction test method, namely if there is a white precipitate of BaSO4, it means that the sample contains cyclamate / the sample is positive. The results of the cyclamate analysis study on 30 samples of sachet packaged coffee drinks taken from the Surabaya keputih market were not detected or did not contain cyclamate, this was because no white precipitate of BaSO4 was formed when analyzed with the BaCl2 reaction. It can be concluded that the 30 samples of coffee drinks that were The cyclamate has been examined and does not contain artificial sweeteners (cyclamate).

Antioxidant Activity Of The Peel Citrus sinensis. L On The Histological Features Of Second Degree Burned Mus musculus Samsudin, Rinza Rahmawati; Arimurti, Anindita Riesti Retno; Puspitasari, Renny Novi
Al-Hayat: Journal of Biology and Applied Biology Vol. 7 No. 2 (2024)
Publisher : Fakultas Sains dan Teknologi, UIN Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/ah.v7i2.17580

Burns are damage to the tissue that does not only occur on the surface of the skin, but can occur under the skin. Globally, burns are the fourth most common type of injury, after traffic accidents, falls and physical abuse. The cost of treating burns is relatively expensive according to the area of the burn, the larger the area of the burn, the higher the cost of treatment. Research for the treatment of burns using herbal ingredients has begun to be carried out by many researchers. One of the typical Indonesian herbal plant ingredients is the Pacitan orange (Citrus sinensis) L Osbeck. This type of research is an experimental research with the aim of looking at the formation of epithelial cells, fibroblasts, and collagen which are formed after being given Pacitan orange peel extract (Citrus sinensis) treatment. The sample of this study used 20 white rats which were divided into 4 groups, namely Group 1 (K1) the burn group without treatment, Group 2 (K2) the burn rats with bioplacenton treatment, Group 3 (K3) the burn rats with NaCl treatment 0.9%, Group 4 (K4) burnt rats treated with extra 100% Pacitan orange peel. From the research results obtained, it can be concluded that the administration of Pacitan Orange Peel extract is proven to accelerate the healing process of second degree burns on the skin of white rats viewed microscopically, namely from increased collagen production, epithelial thickness, and fibroblasts.Keywords: Pacitan orange peel extract, Burns, Mus musculus, histopathology

Identification of Soil Egg Transmitted Helminth on The Nails of Cleaning Workers At TPS Wonocolo District Surabaya City Damayanti, Chiara Shabrina; Artanti, Dita; Ariana, Diah; Samsudin, Rinza Rahmawati
Mukhtabar Journal of Medical Laboratory Technology Vol 3 No 1 (2025): Mukhtabar: Journal of Medical Laboratory Technology (April 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/mjmlt.v3i1.706

Background & Objective: In Indonesia, worm infections are still a big problem in public health because the prevalence is still high, namely 45-65%. even in certain areas that have poor environmental sanitation, high heat, and humidity, the prevalence of worm infections can reach 80%. Worm infections can cause a decline in the health condition, nutrition, and productivity of sufferers, resulting in economic losses, due to a decrease in carbohydrates, protein, and blood, which has an impact on reducing the quality of human resources, one of which is transmission through the nails. This study aims to determine whether or not there are Soil Transmitted Helminth (STH) worm eggs in the nails of cleaning workers in Wonocolo District, Surabaya City. Method: The research method used was deposition (sedimentation) centrifugation using 0.25% NaOH solution, which was analyzed descriptively. The sampling technique used was purposive sampling by taking nail samples from 30 waste cleaning officer respondents. Result: The results of the research showed that 17% of the fingernails of waste cleaners were contaminated with Soil Transmitted Helminth (STH) worm eggs, while 83% of nail samples that were not contaminated with Soil Transmitted Helminth (STH) worm eggs were contaminated. Conclusion: Based on the research results, it can be concluded that there are still cleaning workers in Wonocolo District, Surabaya City, who are contaminated with Soil Transmitted Helminth (STH) worm eggs. This happens because their awareness about personal hygiene, sanitation, Clean and Healthy Living Behavior (CHLS), and the use of Personal Protective Equipment (PPE) while working is still lacking.

Antioxidant Activity Of The Peel Citrus sinensis. L On The Histological Features Of Second Degree Burned Mus musculus Samsudin, Rinza Rahmawati; Arimurti, Anindita Riesti Retno; Puspitasari, Renny Novi
Al-Hayat: Journal of Biology and Applied Biology Vol. 7 No. 2 (2024)
Publisher : Fakultas Sains dan Teknologi, UIN Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/ah.v7i2.17580

Burns are damage to the tissue that does not only occur on the surface of the skin, but can occur under the skin. Globally, burns are the fourth most common type of injury, after traffic accidents, falls and physical abuse. The cost of treating burns is relatively expensive according to the area of the burn, the larger the area of the burn, the higher the cost of treatment. Research for the treatment of burns using herbal ingredients has begun to be carried out by many researchers. One of the typical Indonesian herbal plant ingredients is the Pacitan orange (Citrus sinensis) L Osbeck. This type of research is an experimental research with the aim of looking at the formation of epithelial cells, fibroblasts, and collagen which are formed after being given Pacitan orange peel extract (Citrus sinensis) treatment. The sample of this study used 20 white rats which were divided into 4 groups, namely Group 1 (K1) the burn group without treatment, Group 2 (K2) the burn rats with bioplacenton treatment, Group 3 (K3) the burn rats with NaCl treatment 0.9%, Group 4 (K4) burnt rats treated with extra 100% Pacitan orange peel. From the research results obtained, it can be concluded that the administration of Pacitan Orange Peel extract is proven to accelerate the healing process of second degree burns on the skin of white rats viewed microscopically, namely from increased collagen production, epithelial thickness, and fibroblasts.Keywords: Pacitan orange peel extract, Burns, Mus musculus, histopathology

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