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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) IJMS - Indonesian Journal on Medical Science Indonesian Journal of Community Services Jurnal Riset Kefarmasian Indonesia Jurnal Farmasi dan Sains Indonesia (JFSI) PROFICIO: Jurnal Pengabdian Masyarakat Pharmademica: Jurnal Kefarmasian dan Gizi JAFP (Jurnal Akademi Farmasi Prayoga) Indonesian Journal on Medical Science (IJMS) Media Farmasi Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Margareta Retno Priamsari
Sekolah Tinggi Ilmu Farmasi Nusaputera
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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AKTIVITAS ANTIBAKTERI EKSTRAK PERASAN DAUN MENGKUDU (Morinda citrifolia L.) TERHADAP Escherichia coli SECARA IN VITRO Priamsari, Margareta Retno; Wibowo, Agastia Cicilia
Jurnal Riset Kefarmasian Indonesia Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v2i1.66

Abstract

Noni juice can inhibit the growth of Escherichia coli bacteria. Noni juice extraction needs concentration to extract so that the preparation is more stable in the storage process. The purpose of this study was to determine the antibacterial activity and the amount of the minimum inhibitory concentration of noni juice extract from E. coli bacteria in vitro. This type of experimental research with a completely randomized one-way design. The extract was obtained by concentrating the Noni leaf extract. Extract quality control parameters include organoleptic, yield, drying shrinkage, and qualitative tests of flavonoid and anthraquinone compounds. Antibacterial activity test using the disc diffusion method with an extract concentration of 1.56%; 3.12%; 6.25%; 12.5%; and 25% with 3 replications. Positive control of amoxicillin and negative control of distilled water. Inhibition is known from the zone formed around the paper disc. The data obtained were statistically analyzed using Kruskall Wallis followed by Mann Whitney with a 95% confidence level. The results showed that the variation in the concentration of the noni juice extract had a significant effect (p <0.05). The biggest inhibitory zone was seen at 25% concentration of 10.16 mm and included in the strong category. The minimum inhibitory power was produced at a concentration of 3.12% at 2.50 mm with a weak treatment category.
Formulation of Spinach Leaf Extract (Amaranthus tricolor L.) Shampoo and Antifungal Activity Test Against Pityrosporum ovale Margareta Retno Priamsari; Marcia Angelica Vidigal Loi Pinto; Nanda Dwi Akbar
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol. 22 No. 2 (2025): Jurnal Ilmu Farmasi dan Farmasi Klinis
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v22i2.14276

Abstract

Red spinach leaves contain flavonoid, tannin, alkaloid, saponin and terpenoid that have potential as antifungal compounds. This research is  experimental. The purpose of this reserach is is to find out extract red spinach leaves can inhibit the growth of Pityrosporum ovale and to find out that red spinach leaf extract can be formulated in shampoo. Extraction was carried out using the remaceration method with 70% ethanol solvent and then tested for phytochemical content. Antifungal activity testing of red spinach leaf extract using concentrations of 15; 30; 45; 60 and 75% using the well method with PDA media incubated at 37 for 3x24 hours. The results showed the average inhibition zone activity against Pityrosporum ovale at a concentration of 75% of 19.17 mm statistically showed a significant difference. Formulation of shampoo preparations was carried out on red spinach leaf extract at a concentration of 15% with variations in the formula of Cocamide DEA and CMC-Na. The physical characteristics of the shampoo preparation include organoleeptic test, homogeneity, pH, viscosity, adhesion, spreadability and foam height. The results of testing the antifungal activity of shampoo preparations in formula 1 (17.5 mm); formula 2 (17.83 mm); and formula 3 (16.83 mm), based on statistical tests of antifungal shampoo preparations with a p-value (> 0.05) variations in the concentration of Cocamide DEA and CMC-Na have no significant effect on antifungal activity.
PEMBERDAYAAN PKK PEDURUNGAN LOR UNTUK DAUR ULANG MINYAK JELANTAH DAN SEREH MENJADI SABUN Retno Sri Iswari; Suwarni, Sri; Wahyu Setyaningsih; Margareta Retno Priamsari
Jurnal Pengabdian Masyarakat FKIP UTP Vol 7 No 2 (2026): PROFICIO : Jurnal Abdimas FKIP UTP
Publisher : Fakultas Keguruan dan Ilmu Pendidikan Universitas Tunas Pembangunan Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36728/jpf.v7i2.7080

Abstract

Penggunaan minyak goreng secara berulang masih sering dilakukan oleh masyarakat karena keterbatasan pengetahuan mengenai dampaknya terhadap kesehatan. Minyak jelantah yang digunakan kembali sebagai media menggoreng berpotensi menghasilkan senyawa oksidatif yang berbahaya, sedangkan pembuangannya secara langsung dapat mencemari lingkungan. Di sisi lain Kelurahan Pedurungan Lor memiliki potensi berupa Tim Penggerak PKK yang aktif serta hasil urban farming berupa sereh yang dapat dimanfaatkan sebagai bahan tambahan produk sabun. Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan dan keterampilan Tim Penggerak PKK Kelurahan Pedurungan Lor dalam mengolah minyak jelantah menjadi sabun ramah lingkungan berbasis sereh hasil urban farming. Metode yang digunakan meliputi observasi, penyuluhan, pelatihan, pendampingan, serta evaluasi menggunakan pretest dan posttest. Sebagai media pembelajaran berkelanjutan, disusun video edukasi mengenai pemurnian minyak jelantah, pembuatan minyak sereh, dan proses pembuatan sabun. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan peserta mengenai bahaya penggunaan minyak jelantah, pengelolaan limbah rumah tangga, serta keterampilan dalam memproduksi sabun ramah lingkungan. Program ini mengimplementasikan konsep Green Pharmacy dan Circular Economy melalui pemanfaatan limbah minyak jelantah dan sereh hasil urban farming menjadi produk non-pangan yang aman dan bernilai ekonomi. Kegiatan ini diharapkan dapat meningkatkan kesehatan masyarakat, mengurangi pencemaran lingkungan, serta mendukung pemberdayaan ekonomi keluarga berbasis potensi lokal.
Co-Authors Akbar, Nanda Dwi Aminah, Icha Yuliska Ayu Ina Solichah Bulu, Atalia Tamo Ina Catur Hana Kristanti Dwi Setyonugroho Eka Aprilia Nuraida Icha Yuliska Aminah Kamila, Iffa Maharani, Zahra Febriana Marcia Angelica Vidigal Loi Pinto Maria Mira Susanti Maria Mita Susanti Nada Kurnia Firdaus Nanda Dwi Akbar Nanda Dwi Akbar Odilia Dea Christina Pitarisa, Agustina Putri Pujiastuti, Anasthasia Putri Marsela Danti Retno Sri Iswari Riana Riana, Riana Riana Sesilia Rina Ayu Krismonikawati Sandi Mahesa Yudhantara Sawal, Rizky Ardian Hartanto Sesilia, Riana Setyani, Oky Solichah, Ayu Ina Sri Suwarni Subarjo, Nonik Triliana Warianti Susanti, Maria Mita WAHYU SETYANINGSIH Wahyuningtiastuti, Ananta Wibowo, Agastia Cicilia