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Integrating a Mobile App into Pharmacist-Led Patient Education to Enhance Insulin Pen Self-Administration: A Pre-Experimental One-Group Pretest–Posttest Study Muhammad Thesa Ghozali; Bagas Dwi Nugroho; Anita Agustina Styawan; Satibi Satibi; Gerhard Fortwengel
Journal of Public Health and Pharmacy Vol. 6 No. 2 (2026)
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i2.7365

Abstract

Introduction: Objectives This study was conducted to assess the impact of adding mobile health (mHealth) application on pharmacist-mediated patient counseling to improve accuracy of insulin pen self-administration skills among diabetic patients. Introduction Every day, diabetes mellitus (DM) remain one of the worlds biggest health problems where insulins therapy acts among the mainstay in treating type 1 and ineffective treatment for type 2 diabetes mellitus (T2DM). Insulin pens have increased convenience and adherence to insulin therapy compared with traditional vials and syringes; however, administration errors are still prevalent. These errors typically due to incorrect priming, wrong injection angle or failure to discharge air bubbles can lead to hypoglycemia, hyperglycaemia, and loss of glycemic control, with consequent negative impact on therapeutic outcomes. Although the results provide evidence of substantial improvement in dosing accuracy of insulin, causal inference and generalizability are limited by the single-group pretest–posttest design. Controlled studies moving forward are required to validate these results. The goal of this study was to determine if the addition of these mHealth technologies in pharmacist-led education could help us fill this important procedural gap. Methods: Between December 2023 and May 2024, this study took place in the outpatient clinic of PKU Muhammadiyah Gamping Hospital, Yogyakarta, Indonesia as a pre-experimental, one-group pretest–posttest study. Hundred adult diabetic patients were selected. Structured questionnaires and direct observations based on a standardized insulin pen checklist were used to collect the data. Ethics approval was obtained from Health Research Ethics Committee of PKU Muhammadiyah Gamping Hospital, and all individuals provided written informed consent. Results: At baseline, 29% of participants achieved high proficiency but post-intervention all (100%) achieved this level. Mean accuracy score significantly improved, from 10.28 (SD = 1.36) to 14.12 (SD = 1.03) (p <0.001). Procedural enhancements were to mix insulin and remove air bubbles. Conclusion: Pharmacist-led education with mHealth integration, the application of mobile technology in health monitoring, represents a novel and potentially generalisable approach in efforts to improve practices of insulin self-administration.
The Effect of Differences in Growing Altitude on the Total Flavonoid Content Single Clove Garlic (Allium sativum Linn) Anita Agustina Styawan; Rayhantana Rizky Putra
Journal of Food and Pharmaceutical Sciences Vol 14, No 2 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.25924

Abstract

Single garlic belongs to the Amaryllidaceae family and contains flavonoid compounds with antioxidant activity. However, the use of herbal ingredients often shows inconsistent effects because differences in growing locations, such as soil and climate conditions, can influence the amount of flavonoids produced. The purpose of this study was to determine the difference in total flavonoid content of single garlic (Allium sativum Linn) based on the influence of growing locations in Boyolali Regency and Karanganyar Regency. This study used 2 kg of single garlic (Allium sativum Linn) samples, which were then extracted using the maceration method with 96% ethanol solvent. The total flavonoid content was determined using the UV-Vis spectrophotometry method. The results showed that the quantitative test using UV-Vis spectrophotometry obtained a maximum wavelength of 426 nm with a curve equation of y=0.0151x – 0.0033. The average total flavonoid content from Boyolali Regency was 0.5867 mgQE/g and from Karanganyar Regency was 0.5867 mgQE/g and 0.1495 mgQE/g. Based on statistical test data, it was found that the significance value was 0.002, where the result had a P<0.05 value, which means that there was a significant difference in total flavonoid content based on the growing location.
ANALYSIS OF THE EFFECT OF EXTRACTION METHODS ON TOTAL PHENOLIC CONTENT OF BANGLE RHIZOMES (Zingiber purpureum Roxb.) Styawan, Anita Agustina; Narasia, Narasia; Nurhaini, Rahmi; Arrosyid, Muchson
Journal of Fundamental and Applied Pharmaceutical Science Vol. 7 No. 1 (2026): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v7i1.29242

Abstract

Bangle (Zingiber purpureum Roxb.) is a medicinal plant from the Zingiberaceae family widely used in traditional medicine due to its bioactive compounds, particularly phenolic compounds with anti-inflammatory, antibacterial, and antioxidant properties. The phenolic content of plant materials is strongly influenced by the extraction method; however, comparative studies on Bangle rhizomes using different extraction techniques remain limited. This experimental analytical study aimed to compare the total phenolic content of Bangle rhizomes extracted using maceration and steam distillation methods. Powdered dried rhizomes were extracted by maceration using 96% ethanol, while fresh rhizomes were subjected to steam distillation to obtain essential oil. Total phenolic content was determined by UV–Vis spectrophotometry with Folin–Ciocalteu reagent at a maximum wavelength of 743 nm and an operating time of 60 minutes, expressed as mg gallic acid equivalent (GAE)/g extract. The results showed that the ethanol extract obtained by maceration exhibited a significantly higher total phenolic content (105.03 mg GAE/g) than the distillation product (83.57 mg GAE/g). Statistical analysis using an independent t-test revealed a significant difference between the two extraction methods (p < 0.05). In conclusion, the maceration method using 96% ethanol is more effective than steam distillation in extracting phenolic compounds from Bangle rhizomes.