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All Journal Jurnal Kedokteran Brawijaya IPTEK Journal of Proceedings Series Journal of the Medical Sciences (Berkala Ilmu Kedokteran) e-Journal Pustaka Kesehatan Jurnal Keolahragaan Journal of Agromedicine and Medical Sciences Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) UNEJ e-Proceeding Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Al-sihah: The Public Health Science Journal JPSCR : Journal of Pharmaceutical Science and Clinical Research Supremasi Hukum: Jurnal Penelitian Hukum Jurnal Rekonstruksi dan Estetik Unram Journal of Community Service (UJCS) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Public Health and Preventive Medicine Archive Indonesian Journal of Biomedicine and Clinical Sciences
Ulfa Elfiah
Department Of Plastic Reconstructive And Aesthetic Surgery, Faculty Of Medicine, Universitas Jember, Jember, Indonesia
Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Effect of Robusta coffee extract gel on fibroblast and collagen during proliferative phase of IIB degree-burn on Long Evans rats Ulfa Elfiah; Muhammad Fahmi Naufal; Mochammad Amrun Hidayat
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 54, No 3 (2022)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005403202201

Abstract

IIB Degree-burn takes longer to heal because only a small epithelium component remains. It requires a topical agent that can accelerate the wound healing process. One of the wound healing signs is the increased collagen formation as an extracellular matrix produced by fibroblast in the proliferative phase. This study aimed to prove the effect of Robusta coffee extract gel as a topical agent on increasing the number of fibroblasts and collagen density in IIB degree-burn treatment on Long Evans rats. This study used 24 Long Evans rats which were divided into three groups, namely positive control (silver sulfadiazine), negative control (gel base), and treatment group (2.5% of Robusta coffee extract gel). The results showed a higher number of fibroblast (p<0.05) and a denser collagen density (p<0.05) of the Robusta coffee extract gel compared to the control group on day 8 and day 14. These results indicated that the number of fibroblasts and collagen increases that can scavenge free radicals and stimulate the release of cytokines that play a role in increasing fibroblast proliferation. Robusta coffee affects expanding the number of fibroblasts and collagen density to be an alternative topical agent of second-degree burns treatment.
PERLINDUNGAN HUKUM TERHADAP PASIEN COVID-19 PADA PELAYANAN KESEHATAN DI RUMAH SAKIT: SEBUAH LITERATURE REVIEW I Gede Widhiana Suarda; Fendi Setyawan; Ulfa Elfiah
Supremasi Hukum: Jurnal Penelitian Hukum Vol 32 No 1 (2023)
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/jsh.32.1.40-59

Abstract

Artikel ini merupakan tinjauan literatur awal yang bertujuan untuk menemukan arah penelitian yang tepat terkait dengan perlindungan hukum bagi pasien COVID-19 di Indonesia. Dalam upaya mencapai tujuan tersebut, kajian dalam artikel ini menggunakan metode literatur review dengan mengumpulkan data dari berbagai sumber literatur seperti buku dan jurnal untuk membandingkan hasil penelitian yang satu dengan yang lainnya. Langkah selanjutnya adalah melakukan identifikasi literatur yang relevan dengan topik yang dibahas. Dari proses tersebut, terdapat 6 penelitian yang relevan untuk di-review. Hasil kajian menunjukkan dua kesimpulan. Pertama, topik penelitian tentang perlindungan hukum terhadap pasien COVID-19 pada pelayanan kesehatan di Rumah Sakit merupakan sebuah topik yang perlu diteliti lebih lanjut mengingat topik tersebut belum dibahas dalam penelitian exisiting. Kedua, metode penelitian empiris maupun non doctrinal perlu dilakukan secara holistik dengan subyek utama adalah pasien COVID-19 termasuk para pihak yang berkaitan langsung dengan pelayanan terhadap pasien COVID-19 di rumah sakit, seperti tenaga kesehatan dan juga pihak pimpinan rumah sakit. Dengan demikian, hasil penelitian empiris tentang perlindungan hukum terhadap pasien COVID-19 pada playanan kesehatan di Rumah Sakit akan dapat memperkaya ilmu pengetahuan, baik untuk bidang ilmu-ilmu rumpun kesehatan, hukum, maupun ilmu-ilmu sosial.
ANALISIS KEJADIAN SUMBING BIBIR DAN LANGIT: STUDI DESKRIPTIF BERDASARKAN TINJAUAN GEOGRAFIS Elfiah, Ulfa; Kushariyadi; Wahyudi, Septa S
Jurnal Rekonstruksi dan Estetik Vol. 6 No. 1 (2021): Jurnal Rekonstruksi dan Estetik, Juni 2021
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (430.101 KB) | DOI: 10.20473/jre.v6i1.28230

Abstract

Highlights: Angka kejadian kelainan sumbing bibir dan langit-langit di sepuluh wilayah Jember memiliki angka lebih dari 5 penderita. Profesi orangtua, penggunaan pestisida, dan pencemaran logam berat menjadi faktor resiko terjadinya bibir sumbing dan langit di Jember dimana geografisnya adalah perkebunan dan pertanian. Abstrak: Latar Belakang: Angka kejadian sumbing bibir dan langit-langit masih tinggi di Indonesia sedangkan proses penatalaksanaannya masih belum optimal.  Penelitian  ini  bertujuan  untuk  melakukan  analisis  kejadian sumbing bibir dan langit-langit berdasarkan tinjauan geografis sehingga dapat  menemukan  model  penanganan  yang  tepat  untuk  mengurangi angka kejadian sumbing bibir dan langit-langit. Metode: Penelitian  ini  merupakan  jenis  penelitian  deskriptif  dengan menggunakan  data  rekam  medis  di  salah  satu  rumah  sakit  di  provinsi Jawa  Timur  Indonesia.  Data  yang  digunakan  adalah  data  penderita sumbing  bibir  dan  langit-langit  antara  tahun  2017-2020.  Data  yang diperoleh kemudian dikelompokkan berdasarkan wilayah asal penderita yang  kemudian  dituangkan  dalam  sebuah  peta  untuk  memberikan gambaran  penyebaran  penderita  sumbing  bibir  dan  langit-langit. Sedangkan  karakteristik  penderita  seperti  angka  prevalensi,  jenis kelainan dan pekerjaan orang tua ditampilkan dalam bentuk tabel. Hasil: Penelitian menunjukkan  bahwa  kejadian  kelainan  sumbing  bibir dan  langit-langit  hampir  merata  di  seluruh  wilayah  Jember  bahkan terdapat  sepuluh  wilayah  yang  memiliki  angka  kejadian  lebih  dari  5 penderita.  Tingginya  angka  kejadian  ini  kemungkinan  berhubungan dengan  faktor-faktor  risiko seperti  pekerja  orang  tua  sebagai  petani, penggunaan  pestisida  dan  pencemaran  logam  berat  yang  banyak ditemukan di wilayah Jember yang secara geografis merupakan daerah perkebunan  dan  pertanian  sebagai  penyebab  kejadian  kelainan kongenital ini. Kesimpulan: Pemetaan penderita  secara  geografis  akan  memudahkan dalam menentukan prediksi angka kejadian dan faktor resiko terjadinya kelainan  sumbing  bibir  dan  langit-langit  serta  memudahkan  dalam membuat sistem penanganan penderita sesuai dengan kondisi wilayah masing-masing penderita.
The Antiallergic Potential of Quercetin Compared With Dexamethasone and Prednisolone against Histamine H1 Receptors in Vernal Keratoconjunctivitis Nugraha Wahyu Cahyana; Ulfa Elfiah; Heni Fatmawati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.9478

Abstract

Vernal keratoconjunctivitis is an ophthalmological condition that presents significant challenges, especially in children and adolescents, due to chronic inflammation of the conjunctiva and cornea. This inflammation leads to distressing symptoms such as itching, irritation, and photophobia, which severely impact the quality of life. Traditional treatments for this condition often involve antiallergic medications like dexamethasone, prednisolone, and quercetin. However, understanding the precise mechanisms and comparative effectiveness of these treatments is crucial for improving therapeutic outcomes. In this study, protein structure data for dexamethasone (4UDA), prednisolone (8CC1), and quercetin (1JUH) were sourced from the Protein Data Bank (PDB). The crystal structure of the Histamine H1 Receptor (8X5X) was also retrieved from PDB. In silico modeling was carried out using the Cluspro web server to simulate the interactions between these drugs and the receptor. The analysis revealed that quercetin exhibited the lowest Weighted Score of -1810 in cluster 2, outperforming dexamethasone (-1223) and prednisolone (-1372.4), indicating a higher binding potency to the Histamine H1 Receptor. These findings suggest that quercetin has superior potential compared to dexamethasone and prednisolone for binding to Histamine H1 Receptors in the context of vernal keratoconjunctivitis.
ANALYSIS OF RAT PLATELET COUNT AFTER ELECTRICAL EXPOSURE IN ACUTE AND SUBACUTE PHASE OF BURN INJURY F P H, Fransiska Nooril; Elfiah, Ulfa; Indreswari, Laksmi; Wisudanti, Desie Dwi
Jurnal Rekonstruksi dan Estetik Vol. 4 No. 1 (2019): Jurnal Rekonstruksi dan Estetik, June 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.759 KB) | DOI: 10.20473/jre.v4i1.24347

Abstract

Highlights: In the acute phase of electric burn injury, there was a significant change in platelet count. Contrarily, no significant change in platelet count was observed during the subacute phase of electric burn injury. Abstract: Introduction: Electrical burns are one of the causes of important health burdens throughout the world with incidences varying between 4–18% of all burns. In electrical burns, blood vessels are the heavily damaged tissue characterized by endothelial erosion, followed by adhesion and aggregation of platelets to form a hemostatic plug. The screening test for assessing the formation of a hemostatic plug is platelet count. Platelet count monitoring is very important during the resuscitation phase and treatment periods in severe burns, namely in acute and subacute phases of burns. The purpose of this study is to determine and analyze the changes in the platelet count of rats after electrical exposure in the acute and subacute phases of burns. Methods: This is a quasi-experimental study in vivo with post-test-only group design. The control group in this study was not given electrical exposure and the rat's blood was taken directly after the adaptation process. In the other five groups, P1, P2, P3, P4, and P5 were exposed to 140 V for 17 seconds, then their blood was taken for platelet counts on days 0, 3, 7, 10, and 14 post-exposure. Results : The result of this study based on a Post Hoc LSD test showed that there was a change of platelet number after exposure in the acute phase of burn injury and there was no change of platelet number after exposure in the burning subacute phase. Conclusions: Platelet count difference in acute phase of electric burn injury and no difference in platelet count difference in subacute phase of electric burn injury.
A CASE REPORT: RISK OF ELECTRIC INJURY ON DELAYED INITIAL TREATMENT Elfiah, Ulfa; Suryani, Dissa Yulianita
Jurnal Rekonstruksi dan Estetik Vol. 4 No. 1 (2019): Jurnal Rekonstruksi dan Estetik, June 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (537.597 KB) | DOI: 10.20473/jre.v4i1.24349

Abstract

Highlights: Electric injuries are aggressive burns that can lead to severe tissue necrosis, rhabdomyolysis, and a range of complications, including acute kidney injury (AKI). A multidisciplinary approach and early identification of potential complications in electric injury cases are crucial for reducing the risk of Acute Kidney Injury (AKI) and improving patient outcomes. Abstract: Introduction: Electric Injury is a very aggressive burn injury with severe functional and aesthetic consequences caused by progressive and prolonged tissue necrosis. Necrosis that attacks the skeletal muscle can lead to rhabdomyolysis which results in complications if not treated properly. Case Illustration: A complicated case of electric injury in Dr. Soebandi Jember General Hospital, a 26 years old man came to the emergency room with complaints of severe shortness of breath and urinary disorders. The patient had a history of having an electric shock in his right hand when turning on the fan a week prior of admission. The examination showed that the patient had bilateral pulmonary effusion, generalized edema and acute tubular necrosis (ATN) which was characterized by oliguria and even anuria accompanied by hematuria. Other symptoms experienced by patients are anterior uveitis, subconjunctival hemorrhage, and hematemesis. Discussion: Electric injuries can have a wide range of effects on the body, and their management requires a multidisciplinary approach to address the various complications that may arise. Treatment of electric injuries often involves various surgical procedures, including skin grafts, flaps, or amputation, depending on the severity of the injury. Conclusions: Early identification of potential complications in electric injury cases and effective patient follow-up can reduce the risk of Acute Kidney Injury (AKI) occurrence in patients with electric injuries.
A COMBINATION OF CHEEK FLAP, CARTILAGE INSERTION, AND FAT TRANSFER ON POST-TRAUMA LOWER EYELID ECTROPION RECONSTRUCTION Elfiah, Ulfa; Aprinova, Dicky Primadika
Jurnal Rekonstruksi dan Estetik Vol. 9 No. 2 (2024): Jurnal Rekonstruksi dan Estetik, December 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jre.v9i2.59646

Abstract

Highlights: This study introduces an innovative approach for post-traumatic ectropion reconstruction in children by combining Mustarde rotational cheek flap, cartilage insertion, and fat transfer. This method effectively addresses the challenges of cicatricial ectropion caused by injuries or burns, leading to improved, durable, and cost-effective outcomes in restoring eyelid function and volume. Abstract: Introduction:Ectropion correction surgery is a procedure designed to restore the anterior lamella to its anatomical position. This study aims to propose a combination of cheek flap and fat transfer as a method for post-traumatic ectropion reconstruction surgery. Case Illustration:A 10-year-old girl presented with ectropion caused by scar formation and volume loss in the infraorbital region following a traumatic incident seven years prior. The procedures performed in this case included a Mustarde rotational cheek flap to reconstruct the scar tissue in the infraorbital region that led to the ectropion, pure ear cartilage insertion to repair the damaged tarsal plate or tarsus, and fat transfer to address the volume loss in the infraorbital area. The donor fat was harvested from the inguinal region Discussion: The rationale for using the Mustarde rotational cheek flap, cartilage insertion, and fat transfer was based on the wide donor area, particularly in cases where the vertical dimension exceeds the horizontal dimension. This approach is believed to yield better outcomes compared to other methods, such as skin grafts. In this case, fat transfer was employed to restore the volume lost beneath the scar tissue following trauma. This combination technique is thought to be more durable and to provide superior results compared to alternative methods, while also being economically advantageous. Conclusion: The combination of the Mustarde rotational cheek flap, cartilage insertion, and fat transfer is believed to improve the outcomes of the reconstruction procedure following scar tissue release and correction of volume loss beneath the scar.
Improving Knowledge of Family Nutrition Fulfillment as an Effort to Prevent Congenital Disorders in Couples of Reproductive Age in Rambipuji District, Jember Elfiah, Ulfa; Shinta Rumastika, Nindya; Surya Wahyudi, Septa; Krisno Adji, Novan; Aisyah Amini, Stefia; Faa'is Artama, Alfila; Nadiyatul Husna, Fella; Sahazra Chakra Firdaussaid, Jihad; Nur Hidayah, Siti
Unram Journal of Community Service Vol. 6 No. 2 (2025): June
Publisher : Pascasarjana Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ujcs.v6i2.951

Abstract

The global prevalence of congenital defect reaches 0.992 per 1,000 live births, with a high incidence rate also observed in Jember Regency, particularly in Rambipuji District. Nutrition intake, including protein, is essential to prevent congenital defect, but many sufferers come from families with poor nutritional intake. To prevent congenital defect through education and assistance in planting healthy crops for family nutrition and mapping cases in Jember Regency as a promotive and preventive measure. This study design is a quasi-experimental using pretest and posttest. Participants consisted of 30 married couples aged 14-49 years. The intervention included two educational sessions on congenital defect and the management of healthy crops to be processed into nutritious food. A healthy food recipe book was provided, followed by a cooking demonstration by each participant. The knowledge of couples of reproductive ages increased from pretest to posttest with an average increase of 22.5. Statistical analysis using Wilcoxon showed a significant difference in the knowledge of couples of reproductive ages after the intervention (p=0.000). Providing education and training effectively increases knowledge and skills in managing food for family nutrition among couples of reproductive ages. Similar studies with a larger population can be conducted to review the effectiveness more comprehensively.
Improving Knowledge of Family Nutrition Fulfillment as an Effort to Prevent Congenital Disorders in Couples of Reproductive Age in Rambipuji District, Jember Elfiah, Ulfa; Shinta Rumastika, Nindya; Surya Wahyudi, Septa; Krisno Adji, Novan; Aisyah Amini, Stefia; Faa'is Artama, Alfila; Nadiyatul Husna, Fella; Sahazra Chakra Firdaussaid, Jihad; Nur Hidayah, Siti
Unram Journal of Community Service Vol. 6 No. 2 (2025): June
Publisher : Pascasarjana Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ujcs.v6i2.951

Abstract

The global prevalence of congenital defect reaches 0.992 per 1,000 live births, with a high incidence rate also observed in Jember Regency, particularly in Rambipuji District. Nutrition intake, including protein, is essential to prevent congenital defect, but many sufferers come from families with poor nutritional intake. To prevent congenital defect through education and assistance in planting healthy crops for family nutrition and mapping cases in Jember Regency as a promotive and preventive measure. This study design is a quasi-experimental using pretest and posttest. Participants consisted of 30 married couples aged 14-49 years. The intervention included two educational sessions on congenital defect and the management of healthy crops to be processed into nutritious food. A healthy food recipe book was provided, followed by a cooking demonstration by each participant. The knowledge of couples of reproductive ages increased from pretest to posttest with an average increase of 22.5. Statistical analysis using Wilcoxon showed a significant difference in the knowledge of couples of reproductive ages after the intervention (p=0.000). Providing education and training effectively increases knowledge and skills in managing food for family nutrition among couples of reproductive ages. Similar studies with a larger population can be conducted to review the effectiveness more comprehensively.
An Extension Form of Chiari 1 malformation: A Case Report Wiryaning Putri, Komang Yunita; Novan Krisno Adji; Ulfa Elfiah; Muhammad Yuda Nugraha
Journal of Agromedicine and Medical Sciences Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i3.53709

Abstract

The updated classification of Chiari malformation includes Chiari 1.5 malformation, which explicitly denotes the tonsillar herniation characteristic of Chiari 1 malformation, accompanied by an extended brainstem and a dilated fourth ventricle. We present a Chiari 1 malformation characterized by significant downward herniation of the tonsils and the development of syringomyelia, with no indication of elongation of the fourth ventricle. This example represents an extension of Chiari 1 malformation, which is currently not classified as Chiari 1.5 malformation. A 27-year-old female exhibited cephalic and cervical discomfort for two years. The initial MRI indicated a fall of the cerebellar tonsil beneath the foramen magnum. The midsagittal MRI assessed the degree of tonsillar herniation beneath the foramen magnum. Tonsillar herniation was observed at the C2 level; a spinal MRI revealed syringomyelia affecting the C2 to C3 levels. The patient received a suboccipital craniectomy and C1-C2 laminectomy. There was dural sac pulsation at the C2 level. The patient's cervical discomfort resolved entirely following the surgical procedure. This case represents an extension of Chiari 1 malformation, which is currently not classified as adenotes explicitly 1.5 malformation. 
Co-Authors Adelia Handoko Agnellia Maulidya Utami Aisyah Amini, Stefia Anik Nurmalikah Annisa Sarfina Djunaedy Aprinova, Dicky Primadika Apryanita, Hudayah Ardhina Mahadica Nugroho Arif Arif Aziz, Ayu Munawaroh Candra Agung Wibisana Cicih Komariah D. S. Perdanakusuma Desie Dwi Wisudanti Diana C. Mufida Dini Agustina Duriyanto Oesman Dwita Aryadina Rachmawati Elly Nurus Sakinah, Elly Nurus Ema Fawziyah Ulfah ENNY SUSWATI F P H, Fransiska Nooril Faa'is Artama, Alfila Fajar Kurniawan Hidayat Fajar Kurniawan Hidayat Fajar Kurniawan Hidayat, Fajar Kurniawan Fatimatuzzahra Fatimatuzzahra Fatmalia Fhierziandrini Nuzuliana Fendi Setyawan Heni Fatmawati Hilda Nur Achfidawati I Gede Widhiana Suarda Kirana Nadyatara Krisno Adji, Novan Kristianningrum Dian Sofiana Kushariyadi Kushariyadi Kushariyadi Laksmi Indreswari Luh Putu Ratna Sundari Luluk Mauludyahwati M. R. Hutagalung Meytika Fauziah Sugiartanti Misnawi Misnawi Mochammad Amrun Hidayat Mochammad Amrun Hidayat Muhammad A. Shodikin Muhammad Fahmi Naufal Muhammad Izat Fuadi Muhammad Yuda Nugraha Nadiyatul Husna, Fella Nikmatul Maula Nur Rahmadani Nindya Shinta Rumastika Novan Krisno Adji Nugraha Wahyu Cahyana Nur Hidayah, Siti Phill T Koesbandriati Ramadhani, Alfiyah Rena Normasari Rosanti, Maidy Frista Sahazra Chakra Firdaussaid, Jihad Satmoko, Valentino Yosarian Sheila Rachmania Shinta Rumastika, Nindya Surya Wahyudi, Septa Suryani, Dissa Yulianita Wahyu Rachmadi Akbar Wahyudi, Septa S Waskito Setiaji Winaspita Aulia Putri Windharto, Agus Wiryaning Putri, Komang Yunita Yuli Hermansyah